Click here to switch to the map view.

The map label for this gene is qseC [H]

Identifier: 238896534

GI number: 238896534

Start: 4514854

End: 4516203

Strand: Direct

Name: qseC [H]

Synonym: KP1_4721

Alternate gene names: 238896534

Gene position: 4514854-4516203 (Clockwise)

Preceding gene: 238896533

Following gene: 238896535

Centisome position: 86.02

GC content: 63.78

Gene sequence:

>1350_bases
ATGAAACGACTTGCCCGCCTGAGCCTGCGCCTGCGCCTGACGCTGCTGTTTGCCGTACTGACCACCGCCGCCTGGGGGAT
GGCCAGCGTTATCGCCTGGCAGCAGACCAGCAAAAAGCTGGATAAGCTGTTCGATACCCAGCAGCTGCTGTTCGCTCGCC
GCCTGAGCGTCATGCATTTCGATGAACTGCGCGCCCCGCCCGCCTTGCTCGGGGAAAAGAAAAAGGTACGCCACGGGCAC
ATCGACGACGACGCGCTGGCGTTCGCCATCTTCACCCGCGACGGCAAAATGGTGCTTAATGACGGCGAGAACGGAGAGGA
TATTCAGTGGAATTCGCAGCGCGAGGGATTCAGCGATGGCTATCTGCGTGACGACGATGACGAGTGGCGTTTCCTGTGGT
TAACCACCGCCGACGGCCGCTACCGCATCGCCGTCGGCCAGGAGTGGGATTACCGGCGCGAAATGGCGATGGATATCGTG
ACCTCGCAGCTCACCCCGTGGATGGTTGCCCTGCCGCTGATGTTCGTGCTGCTCATCGTGCTGTTAAGCCGCGAGCTGGC
GCCATTGAAAAATCTGGCGCGCACGCTGCGCCTGCGCGCGCCGGACTCGGCGGATTCGCTCAGCGTGGAGAAGATCCCCG
CCGAAGTTCGCCCGCTGGTCGAAGCGCTGAATCAGCTGTTCCGACGCACTCACGACGCCATGCTGCGCGAGCGTCGGTTT
ACCTCTGATGCCGCCCATGAGCTACGCAGCCCGCTGGCGGCGCTGAAGGTGCAGACCGAAGTCGCCCAACTCTCCCTGGA
CGATCCCGAAGGGCGTGAGAAAGCGTTGGATCAGCTCCACCAGGGGATCGATCGCGCCACCCGACTGGTGGATCAGCTGC
TGACGCTGTCGCGGCTGGACTCGCTCGCCCAACTGGATGATGTGCAGCAGGTCGCCATCGCCGATCTGCTGCAGTCGGCA
GTGATGGAGATGTATCACCCGGCGCAGCAGTCCGGGATTGAGCTGCGCCTGCATCTTAATGCCAGCCATATCGTCCGCAC
CGGCCAGCCGCTGCTGCTCAGTATGCTGGTGCGTAATCTGCTGGATAACGCCGTACGCTATAGCCCGCGCGGCAGCCAGG
TCGATATCACGCTCAACGCCCGCGAGTTCCGGGTGCGCGATAACGGCCCAGGCATTAGCCCGCAGGCGCTCTCGCGCATT
GGCGAGCGTTTTTATCGTCCGCCGGGGCAGGAGGCGCCGGGCAGCGGCCTGGGCTTGTCGATCGTCCGGCGCATCGCCTC
GCTGCACGGCATGCAGGTTGATTTTGCCAACGCGCGCGACGGCGGCTTCGAGGCCCGCGTGTACTGGTAG

Upstream 100 bases:

>100_bases
CCAGCAACGCCGTGGAAGTTCACGTCCATCATCTGCGCCGCAAGCTCGGCAGCGACTTTATCCGTACCGTCCACGGCATC
GGCTATACCCTGGGTGACGC

Downstream 100 bases:

>100_bases
CGAGATTATTGCTCATTTGGCAAAAGACTTTGCACATTTTGCTCATTTTACTGCCCCGCTTCGCGGGGTAAGATCGTCGG
CAAATTTTCATATATGAGGG

Product: sensor protein QseC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MKRLARLSLRLRLTLLFAVLTTAAWGMASVIAWQQTSKKLDKLFDTQQLLFARRLSVMHFDELRAPPALLGEKKKVRHGH
IDDDALAFAIFTRDGKMVLNDGENGEDIQWNSQREGFSDGYLRDDDDEWRFLWLTTADGRYRIAVGQEWDYRREMAMDIV
TSQLTPWMVALPLMFVLLIVLLSRELAPLKNLARTLRLRAPDSADSLSVEKIPAEVRPLVEALNQLFRRTHDAMLRERRF
TSDAAHELRSPLAALKVQTEVAQLSLDDPEGREKALDQLHQGIDRATRLVDQLLTLSRLDSLAQLDDVQQVAIADLLQSA
VMEMYHPAQQSGIELRLHLNASHIVRTGQPLLLSMLVRNLLDNAVRYSPRGSQVDITLNAREFRVRDNGPGISPQALSRI
GERFYRPPGQEAPGSGLGLSIVRRIASLHGMQVDFANARDGGFEARVYW

Sequences:

>Translated_449_residues
MKRLARLSLRLRLTLLFAVLTTAAWGMASVIAWQQTSKKLDKLFDTQQLLFARRLSVMHFDELRAPPALLGEKKKVRHGH
IDDDALAFAIFTRDGKMVLNDGENGEDIQWNSQREGFSDGYLRDDDDEWRFLWLTTADGRYRIAVGQEWDYRREMAMDIV
TSQLTPWMVALPLMFVLLIVLLSRELAPLKNLARTLRLRAPDSADSLSVEKIPAEVRPLVEALNQLFRRTHDAMLRERRF
TSDAAHELRSPLAALKVQTEVAQLSLDDPEGREKALDQLHQGIDRATRLVDQLLTLSRLDSLAQLDDVQQVAIADLLQSA
VMEMYHPAQQSGIELRLHLNASHIVRTGQPLLLSMLVRNLLDNAVRYSPRGSQVDITLNAREFRVRDNGPGISPQALSRI
GERFYRPPGQEAPGSGLGLSIVRRIASLHGMQVDFANARDGGFEARVYW
>Mature_449_residues
MKRLARLSLRLRLTLLFAVLTTAAWGMASVIAWQQTSKKLDKLFDTQQLLFARRLSVMHFDELRAPPALLGEKKKVRHGH
IDDDALAFAIFTRDGKMVLNDGENGEDIQWNSQREGFSDGYLRDDDDEWRFLWLTTADGRYRIAVGQEWDYRREMAMDIV
TSQLTPWMVALPLMFVLLIVLLSRELAPLKNLARTLRLRAPDSADSLSVEKIPAEVRPLVEALNQLFRRTHDAMLRERRF
TSDAAHELRSPLAALKVQTEVAQLSLDDPEGREKALDQLHQGIDRATRLVDQLLTLSRLDSLAQLDDVQQVAIADLLQSA
VMEMYHPAQQSGIELRLHLNASHIVRTGQPLLLSMLVRNLLDNAVRYSPRGSQVDITLNAREFRVRDNGPGISPQALSRI
GERFYRPPGQEAPGSGLGLSIVRRIASLHGMQVDFANARDGGFEARVYW

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=449, Percent_Identity=66.369710467706, Blast_Score=603, Evalue=1e-174,
Organism=Escherichia coli, GI1786783, Length=360, Percent_Identity=26.6666666666667, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790551, Length=286, Percent_Identity=32.1678321678322, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788279, Length=297, Percent_Identity=26.5993265993266, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1786600, Length=215, Percent_Identity=30.6976744186047, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1786912, Length=213, Percent_Identity=32.8638497652582, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788393, Length=272, Percent_Identity=31.6176470588235, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790861, Length=242, Percent_Identity=29.7520661157025, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790346, Length=241, Percent_Identity=28.6307053941909, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787894, Length=233, Percent_Identity=25.7510729613734, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789149, Length=237, Percent_Identity=22.7848101265823, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789808, Length=245, Percent_Identity=23.265306122449, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87082128, Length=271, Percent_Identity=26.9372693726937, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50882; Mature: 50882

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLARLSLRLRLTLLFAVLTTAAWGMASVIAWQQTSKKLDKLFDTQQLLFARRLSVMHF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DELRAPPALLGEKKKVRHGHIDDDALAFAIFTRDGKMVLNDGENGEDIQWNSQREGFSDG
HHHCCCHHHHCCCHHHCCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCC
YLRDDDDEWRFLWLTTADGRYRIAVGQEWDYRREMAMDIVTSQLTPWMVALPLMFVLLIV
CCCCCCCCEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LLSRELAPLKNLARTLRLRAPDSADSLSVEKIPAEVRPLVEALNQLFRRTHDAMLRERRF
HHHHCHHHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
TSDAAHELRSPLAALKVQTEVAQLSLDDPEGREKALDQLHQGIDRATRLVDQLLTLSRLD
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLAQLDDVQQVAIADLLQSAVMEMYHPAQQSGIELRLHLNASHIVRTGQPLLLSMLVRNL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEEECHHHHHHCCCHHHHHHHHHHH
LDNAVRYSPRGSQVDITLNAREFRVRDNGPGISPQALSRIGERFYRPPGQEAPGSGLGLS
HHHHHEECCCCCEEEEEEECEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHH
IVRRIASLHGMQVDFANARDGGFEARVYW
HHHHHHHHCCCEEEECCCCCCCCEEEEEC
>Mature Secondary Structure
MKRLARLSLRLRLTLLFAVLTTAAWGMASVIAWQQTSKKLDKLFDTQQLLFARRLSVMHF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DELRAPPALLGEKKKVRHGHIDDDALAFAIFTRDGKMVLNDGENGEDIQWNSQREGFSDG
HHHCCCHHHHCCCHHHCCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCC
YLRDDDDEWRFLWLTTADGRYRIAVGQEWDYRREMAMDIVTSQLTPWMVALPLMFVLLIV
CCCCCCCCEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LLSRELAPLKNLARTLRLRAPDSADSLSVEKIPAEVRPLVEALNQLFRRTHDAMLRERRF
HHHHCHHHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
TSDAAHELRSPLAALKVQTEVAQLSLDDPEGREKALDQLHQGIDRATRLVDQLLTLSRLD
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLAQLDDVQQVAIADLLQSAVMEMYHPAQQSGIELRLHLNASHIVRTGQPLLLSMLVRNL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEEECHHHHHHCCCHHHHHHHHHHH
LDNAVRYSPRGSQVDITLNAREFRVRDNGPGISPQALSRIGERFYRPPGQEAPGSGLGLS
HHHHHEECCCCCEEEEEEECEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHH
IVRRIASLHGMQVDFANARDGGFEARVYW
HHHHHHHHCCCEEEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]