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The map label for this gene is mdaB [H]

Identifier: 238896536

GI number: 238896536

Start: 4516666

End: 4516890

Strand: Direct

Name: mdaB [H]

Synonym: KP1_4723

Alternate gene names: 238896536

Gene position: 4516666-4516890 (Clockwise)

Preceding gene: 238896535

Following gene: 238896537

Centisome position: 86.06

GC content: 51.56

Gene sequence:

>225_bases
ATGCTTTCTCTGACCTGGAACGCGCCGATGGAAGCCTTCACCGACAAAGACCAGTTCTTCCACGGCGTCGGCGTTGACGG
CGTTTACCTGCCGTTCCATAAAGCCAATCAGTTCCTCGGCATGGAGGCATTGCCGACCTTTATCGCCAACGACGTGATTA
AAATGCCTGATGTCCCACGGTATATCGCAGAATATCGCAAGCATCTGGCGGAAATTTTTGGTTAA

Upstream 100 bases:

>100_bases
TTACCGAAGGCCACGGCTCGCTGTACGCCAGCGATGGCCGTACCCGCTCCGACGCCAGCAAAAAATATGGCTCCGGCGGC
CTGGTGCAGGGGAAAAATAT

Downstream 100 bases:

>100_bases
CTAGGGGTCTATGCTCTACATATTTCGAGTTATTGGAACCTGGAGTATGACAAGATCCACACAGAAGGAGTTGAGTTAAC
CATGTTAACAGTGATTGCAG

Product: modulator of drug activity B

Products: NADP; a reduced quinone; reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 74; Mature: 74

Protein sequence:

>74_residues
MLSLTWNAPMEAFTDKDQFFHGVGVDGVYLPFHKANQFLGMEALPTFIANDVIKMPDVPRYIAEYRKHLAEIFG

Sequences:

>Translated_74_residues
MLSLTWNAPMEAFTDKDQFFHGVGVDGVYLPFHKANQFLGMEALPTFIANDVIKMPDVPRYIAEYRKHLAEIFG
>Mature_74_residues
MLSLTWNAPMEAFTDKDQFFHGVGVDGVYLPFHKANQFLGMEALPTFIANDVIKMPDVPRYIAEYRKHLAEIFG

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To H.influenzae HI_0648 and S.pombe SPAC5H10.05c [H]

Homologues:

Organism=Escherichia coli, GI1789406, Length=74, Percent_Identity=93.2432432432432, Blast_Score=148, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: NA

Molecular weight: Translated: 8462; Mature: 8462

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLTWNAPMEAFTDKDQFFHGVGVDGVYLPFHKANQFLGMEALPTFIANDVIKMPDVPR
CCCCCCCCCHHHHCCHHHHHCCCCCCCEECCHHHCCHHCCHHHHHHHHHHCCCCCCCCCH
YIAEYRKHLAEIFG
HHHHHHHHHHHHCC
>Mature Secondary Structure
MLSLTWNAPMEAFTDKDQFFHGVGVDGVYLPFHKANQFLGMEALPTFIANDVIKMPDVPR
CCCCCCCCCHHHHCCHHHHHCCCCCCCEECCHHHCCHHCCHHHHHHHHHHCCCCCCCCCH
YIAEYRKHLAEIFG
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH; a quinone; Acceptor; NADPH [C]

Specific reaction: NADPH + a quinone = NADP + a reduced quinone Acceptor + NADPH = reduced acceptor + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]