| Definition | Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome. |
|---|---|
| Accession | NC_012731 |
| Length | 5,248,520 |
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The map label for this gene is hypF [H]
Identifier: 238896168
GI number: 238896168
Start: 4139037
End: 4141271
Strand: Reverse
Name: hypF [H]
Synonym: KP1_4314
Alternate gene names: 238896168
Gene position: 4141271-4139037 (Counterclockwise)
Preceding gene: 238896169
Following gene: 238896167
Centisome position: 78.9
GC content: 66.89
Gene sequence:
>2235_bases ATGAACGGGGTGCAAATCCGCATTCGCGGTAAAGTGCAGGGGGTCGGTTTCCGCCCCTTTGTCTGGCAGCTGGCCCGGGC GCAGGCCCGCTGCGGCGATGTCTGTAACGACGGCGACGGCGTACTGGTGCGGCTGGTCGGGGGCGACGACGGTTTTACTG CCGCTCTGGCTGACCACTGCCCGCCGCTGGCGCGGATCGACAGTACCGCCTGCATTCCCTATCGCTGGACGGCCATGCCG CAGGATTTCACCATCCGCGAGAGCGGGAAGGGACGGATGCGCACTCAGATCGTGCCCGATGCCGCGACCTGCCCGGCGTG CCTCGCGGAGATGAACGATCCCCGGGCGCGCCGCTACCGCTATCCTTTTATCAACTGCACCCACTGCGGGCCGCGGCTGA CCATTATTCGCGCCATGCCCTACGACCGGCCCTTCACCGCAATGGCGCCGTTCCCGCTCTGTTCCCCTTGTGAAGCGGAA TTCCGCGATCCTGCCGATCGCCGTTTTCACGCCCAGCCGGTGGCCTGCCCCGACTGCGGGCCGCGACTGGAATGGCGGGC AGAGGGGGAAGCGCTGGACGGCGAGGCGGCGCTGCAGGCGGCTATCGCCCGGCTGGCGGCGGGCGACATCGTGGCGATAA AAGGCATCGGCGGCTTTCATCTGGCCTGCGATGCCGGTAACCCCGCTGCCGTTGCCACGCTGCGGGCGCGAAAACACCGC CCGGCAAAACCGCTGGCGGTAATGCTGCCGACGGCAACGGGCTTACCCGCCGCCGCCGCGGCGCTGATGGGCTCCCCGGC GGCGCCCATCGTACTGATTGCCAAAGCGCAGGTCTCCGGCCTGTGCGACGAAATAGCGCCAGGGCTTGCGGAAGTTGGGG TGATGCTGCCGTCTAATCCGCTGCAGCATTTGCTTCTGCAGGGCCTGGCGCGCCCCATCGTAATGACCTCCGGCAATCTT AGCGGCCGTCCGCCGGCGTTAAGTAATGCTCAGGCGCTCAATGAGTTAGCCGACATTGCCGACGGCTTTCTCTTGCATAA TCGCGACATCGTACAGCGGATGGATGATTCACTGGTGCGCTCAAGCGGTGAAATGCTGCGCCGCGCCCGGGGCTACGTCC CGGACGCGCTGCCGCTGCCGCCAGGGCTAGGAGACATCCCGCCGCTGCTGGCTCTCGGCGCGGATATGAAAAATACTTTC TGCCTGGCGCGCGGCAGCGAAGCGGTGCTGAGCCAGCACTTTGGCGATCTTGGCGAGGAAGGTGTTGAACAGCAGTGGCG CAGCGCCCTGCAGCTGATGCAGAGCATTTACGCGTTTGTGCCGCAGCGGGTGGTGGTTGATGCCCATCCCGGCTATCGCT CAACGCAGTGGGCGGCCTCCCTGCCCCTGCCGCTGGAGACAGTGCTGCATCACCATGCCCACGCCGCGGCGTGCCTGGCG GAGCACCGCTGGCCGCTTGACGGCGGGGACGTTATCGCCCTGACACTCGACGGTATTGGTATGGGGGAGAACGGCGCGCT GTGGGGCGGGGAGTGCCTGCGGGTCAACTATCGCGAATGCGAACATCTTGGCGGGCTGCCGGCCGTCGCGCTGCCAGGGG GGGACCTGGCGGCACGCCAGCCGTGGCGAAATTTGCTGGCCCACTGTCTGGCGTTTGTCCCTGACTGGCAGGATTATCCG CAGGCCGCCACCCTGCGCCAGCGCAACTGGCCGCTGCTGGCGCAGGCCATCGAGCGCGGGATTAACGCGCCGCGCGCTTC ATCCTGCGGACGGCTGTTTGATGCCGTTGCCTGCGCCCTGGATTGCGCGCCGGAGAGTCTGAGCTATGAAGGCGAAGCGG CCTGTCGGCTGGAGGCGCTGGCCGCCAGCTGCCCCGGCGTCAGCCACCCGGTTACGCTGCCTTGGCGCGACGACGCGCTG GATTTAGCGACCTTCTGGCGGCAATGGCTGAGCTGGCAGGCGACTCCGGCGCAGAAAGCCTGGGCATTCCACGACGCCCT GGCCTGTGGACTGGCGGCGATGGCCCGCGACTGCGCCACCGTCCGCGGCATCGACACGATGGTCTGCAGCGGCGGGGTGC TGCATAACCGCCTGCTGGCGGCGCGATTGACCTTTTATCTGGCGGATTTTACTCTGCTGTTTGCACAGCAGTTGCCGGCC GGCGACGGCGCAATCGCCTATGGTCAGGCGGTGATCGCCGCCGCCCGCGGGCAGGCTCAAGGAATAAAACCATGA
Upstream 100 bases:
>100_bases TGTGCCCGACGCACGCCCTCGTGTGCGTTGACCGCAACAAACTTGAGCAGATGAATATCGAGAAACGTCGCCGTACGGCG CTGGCCTGGTAAGTCAAGGC
Downstream 100 bases:
>100_bases TAATGACAGTTTTACGCCAGCAGCCGCGCGCCGCGGGTCTGGTGCTGGGGTTGATCGCGGCGAATTTACTGGCCTGGTGC TGGGCGCTGCAGGCCTTTGG
Product: hydrogenase maturation protein
Products: NA
Alternate protein names: Carbamoyl phosphate-converting enzyme hypF; [NiFe]-hydrogenase maturation factor hypF; Hydrogenase maturation protein hypF [H]
Number of amino acids: Translated: 744; Mature: 744
Protein sequence:
>744_residues MNGVQIRIRGKVQGVGFRPFVWQLARAQARCGDVCNDGDGVLVRLVGGDDGFTAALADHCPPLARIDSTACIPYRWTAMP QDFTIRESGKGRMRTQIVPDAATCPACLAEMNDPRARRYRYPFINCTHCGPRLTIIRAMPYDRPFTAMAPFPLCSPCEAE FRDPADRRFHAQPVACPDCGPRLEWRAEGEALDGEAALQAAIARLAAGDIVAIKGIGGFHLACDAGNPAAVATLRARKHR PAKPLAVMLPTATGLPAAAAALMGSPAAPIVLIAKAQVSGLCDEIAPGLAEVGVMLPSNPLQHLLLQGLARPIVMTSGNL SGRPPALSNAQALNELADIADGFLLHNRDIVQRMDDSLVRSSGEMLRRARGYVPDALPLPPGLGDIPPLLALGADMKNTF CLARGSEAVLSQHFGDLGEEGVEQQWRSALQLMQSIYAFVPQRVVVDAHPGYRSTQWAASLPLPLETVLHHHAHAAACLA EHRWPLDGGDVIALTLDGIGMGENGALWGGECLRVNYRECEHLGGLPAVALPGGDLAARQPWRNLLAHCLAFVPDWQDYP QAATLRQRNWPLLAQAIERGINAPRASSCGRLFDAVACALDCAPESLSYEGEAACRLEALAASCPGVSHPVTLPWRDDAL DLATFWRQWLSWQATPAQKAWAFHDALACGLAAMARDCATVRGIDTMVCSGGVLHNRLLAARLTFYLADFTLLFAQQLPA GDGAIAYGQAVIAAARGQAQGIKP
Sequences:
>Translated_744_residues MNGVQIRIRGKVQGVGFRPFVWQLARAQARCGDVCNDGDGVLVRLVGGDDGFTAALADHCPPLARIDSTACIPYRWTAMP QDFTIRESGKGRMRTQIVPDAATCPACLAEMNDPRARRYRYPFINCTHCGPRLTIIRAMPYDRPFTAMAPFPLCSPCEAE FRDPADRRFHAQPVACPDCGPRLEWRAEGEALDGEAALQAAIARLAAGDIVAIKGIGGFHLACDAGNPAAVATLRARKHR PAKPLAVMLPTATGLPAAAAALMGSPAAPIVLIAKAQVSGLCDEIAPGLAEVGVMLPSNPLQHLLLQGLARPIVMTSGNL SGRPPALSNAQALNELADIADGFLLHNRDIVQRMDDSLVRSSGEMLRRARGYVPDALPLPPGLGDIPPLLALGADMKNTF CLARGSEAVLSQHFGDLGEEGVEQQWRSALQLMQSIYAFVPQRVVVDAHPGYRSTQWAASLPLPLETVLHHHAHAAACLA EHRWPLDGGDVIALTLDGIGMGENGALWGGECLRVNYRECEHLGGLPAVALPGGDLAARQPWRNLLAHCLAFVPDWQDYP QAATLRQRNWPLLAQAIERGINAPRASSCGRLFDAVACALDCAPESLSYEGEAACRLEALAASCPGVSHPVTLPWRDDAL DLATFWRQWLSWQATPAQKAWAFHDALACGLAAMARDCATVRGIDTMVCSGGVLHNRLLAARLTFYLADFTLLFAQQLPA GDGAIAYGQAVIAAARGQAQGIKP >Mature_744_residues MNGVQIRIRGKVQGVGFRPFVWQLARAQARCGDVCNDGDGVLVRLVGGDDGFTAALADHCPPLARIDSTACIPYRWTAMP QDFTIRESGKGRMRTQIVPDAATCPACLAEMNDPRARRYRYPFINCTHCGPRLTIIRAMPYDRPFTAMAPFPLCSPCEAE FRDPADRRFHAQPVACPDCGPRLEWRAEGEALDGEAALQAAIARLAAGDIVAIKGIGGFHLACDAGNPAAVATLRARKHR PAKPLAVMLPTATGLPAAAAALMGSPAAPIVLIAKAQVSGLCDEIAPGLAEVGVMLPSNPLQHLLLQGLARPIVMTSGNL SGRPPALSNAQALNELADIADGFLLHNRDIVQRMDDSLVRSSGEMLRRARGYVPDALPLPPGLGDIPPLLALGADMKNTF CLARGSEAVLSQHFGDLGEEGVEQQWRSALQLMQSIYAFVPQRVVVDAHPGYRSTQWAASLPLPLETVLHHHAHAAACLA EHRWPLDGGDVIALTLDGIGMGENGALWGGECLRVNYRECEHLGGLPAVALPGGDLAARQPWRNLLAHCLAFVPDWQDYP QAATLRQRNWPLLAQAIERGINAPRASSCGRLFDAVACALDCAPESLSYEGEAACRLEALAASCPGVSHPVTLPWRDDAL DLATFWRQWLSWQATPAQKAWAFHDALACGLAAMARDCATVRGIDTMVCSGGVLHNRLLAARLTFYLADFTLLFAQQLPA GDGAIAYGQAVIAAARGQAQGIKP
Specific function: Along with hypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carb
COG id: COG0068
COG function: function code O; Hydrogenase maturation factor
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 YrdC-like domain [H]
Homologues:
Organism=Escherichia coli, GI2367152, Length=734, Percent_Identity=74.6594005449591, Blast_Score=1043, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001792 - InterPro: IPR017968 - InterPro: IPR004421 - InterPro: IPR017945 - InterPro: IPR006070 - InterPro: IPR011125 [H]
Pfam domain/function: PF00708 Acylphosphatase; PF01300 Sua5_yciO_yrdC; PF07503 zf-HYPF [H]
EC number: NA
Molecular weight: Translated: 79587; Mature: 79587
Theoretical pI: Translated: 6.88; Mature: 6.88
Prosite motif: PS00150 ACYLPHOSPHATASE_1 ; PS51160 ACYLPHOSPHATASE_3 ; PS51163 YRDC
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
3.6 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 5.9 %Cys+Met (Translated Protein) 3.6 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 5.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNGVQIRIRGKVQGVGFRPFVWQLARAQARCGDVCNDGDGVLVRLVGGDDGFTAALADHC CCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHCC PPLARIDSTACIPYRWTAMPQDFTIRESGKGRMRTQIVPDAATCPACLAEMNDPRARRYR CCHHHCCCCEECCEEECCCCCCCEEECCCCCCEEEEECCCCHHHHHHHHHCCCCHHHHCC YPFINCTHCGPRLTIIRAMPYDRPFTAMAPFPLCSPCEAEFRDPADRRFHAQPVACPDCG CCEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCC PRLEWRAEGEALDGEAALQAAIARLAAGDIVAIKGIGGFHLACDAGNPAAVATLRARKHR CCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCHHHHHHHHHCCC PAKPLAVMLPTATGLPAAAAALMGSPAAPIVLIAKAQVSGLCDEIAPGLAEVGVMLPSNP CCCCEEEEECCCCCCHHHHHHHHCCCCCCEEEEECHHHHHHHHHHCCCHHHHCEECCCCH LQHLLLQGLARPIVMTSGNLSGRPPALSNAQALNELADIADGFLLHNRDIVQRMDDSLVR HHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCEECCHHHHHHHHHHHHH SSGEMLRRARGYVPDALPLPPGLGDIPPLLALGADMKNTFCLARGSEAVLSQHFGDLGEE HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHH GVEQQWRSALQLMQSIYAFVPQRVVVDAHPGYRSTQWAASLPLPLETVLHHHAHAAACLA HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH EHRWPLDGGDVIALTLDGIGMGENGALWGGECLRVNYRECEHLGGLPAVALPGGDLAARQ HCCCCCCCCCEEEEEECCCCCCCCCCEECCCEEEECHHHHHHCCCCCEEEECCCCHHHCC PWRNLLAHCLAFVPDWQDYPQAATLRQRNWPLLAQAIERGINAPRASSCGRLFDAVACAL HHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH DCAPESLSYEGEAACRLEALAASCPGVSHPVTLPWRDDALDLATFWRQWLSWQATPAQKA HCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCHHHH WAFHDALACGLAAMARDCATVRGIDTMVCSGGVLHNRLLAARLTFYLADFTLLFAQQLPA HHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC GDGAIAYGQAVIAAARGQAQGIKP CCCCHHHHHHHHHHHCCCCCCCCC >Mature Secondary Structure MNGVQIRIRGKVQGVGFRPFVWQLARAQARCGDVCNDGDGVLVRLVGGDDGFTAALADHC CCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHCC PPLARIDSTACIPYRWTAMPQDFTIRESGKGRMRTQIVPDAATCPACLAEMNDPRARRYR CCHHHCCCCEECCEEECCCCCCCEEECCCCCCEEEEECCCCHHHHHHHHHCCCCHHHHCC YPFINCTHCGPRLTIIRAMPYDRPFTAMAPFPLCSPCEAEFRDPADRRFHAQPVACPDCG CCEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCC PRLEWRAEGEALDGEAALQAAIARLAAGDIVAIKGIGGFHLACDAGNPAAVATLRARKHR CCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCHHHHHHHHHCCC PAKPLAVMLPTATGLPAAAAALMGSPAAPIVLIAKAQVSGLCDEIAPGLAEVGVMLPSNP CCCCEEEEECCCCCCHHHHHHHHCCCCCCEEEEECHHHHHHHHHHCCCHHHHCEECCCCH LQHLLLQGLARPIVMTSGNLSGRPPALSNAQALNELADIADGFLLHNRDIVQRMDDSLVR HHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCEECCHHHHHHHHHHHHH SSGEMLRRARGYVPDALPLPPGLGDIPPLLALGADMKNTFCLARGSEAVLSQHFGDLGEE HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHH GVEQQWRSALQLMQSIYAFVPQRVVVDAHPGYRSTQWAASLPLPLETVLHHHAHAAACLA HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH EHRWPLDGGDVIALTLDGIGMGENGALWGGECLRVNYRECEHLGGLPAVALPGGDLAARQ HCCCCCCCCCEEEEEECCCCCCCCCCEECCCEEEECHHHHHHCCCCCEEEECCCCHHHCC PWRNLLAHCLAFVPDWQDYPQAATLRQRNWPLLAQAIERGINAPRASSCGRLFDAVACAL HHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH DCAPESLSYEGEAACRLEALAASCPGVSHPVTLPWRDDALDLATFWRQWLSWQATPAQKA HCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCHHHH WAFHDALACGLAAMARDCATVRGIDTMVCSGGVLHNRLLAARLTFYLADFTLLFAQQLPA HHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC GDGAIAYGQAVIAAARGQAQGIKP CCCCHHHHHHHHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9278503; 8661925; 12206761 [H]