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The map label for this gene is hoxN [H]

Identifier: 238896167

GI number: 238896167

Start: 4138027

End: 4139040

Strand: Reverse

Name: hoxN [H]

Synonym: KP1_4313

Alternate gene names: 238896167

Gene position: 4139040-4138027 (Counterclockwise)

Preceding gene: 238896168

Following gene: 238896163

Centisome position: 78.86

GC content: 61.93

Gene sequence:

>1014_bases
ATGATAATGACAGTTTTACGCCAGCAGCCGCGCGCCGCGGGTCTGGTGCTGGGGTTGATCGCGGCGAATTTACTGGCCTG
GTGCTGGGCGCTGCAGGCCTTTGGCGACAGCGGCGCGCTGATGGCCGCCAGCCTGCTGGCCTGGGGCTACGGCCTGCGCC
ACGCGGTGGACGCCGACCATATTGCGGCGATTGATAACGTGACCCGCAAGATGATGCAGCAGGGGCGGCGGCCTTTCGCC
GTCGGGGCGTGGTTTTCGCTGGGCCACTCATCGATTGTGGTGCTGGCCTCGGCGGCGATTGCCGCGACCGCCACCGCCTT
CAGCACGCAGATGAGCTGGCTGCATGATACCGGCAGCGTTATCGGCACCGCGGTGTCGGCCCTGTTTTTACTGGCGATGG
CCTTTATCAACCTGGTGATTTTACGCAGCGTGTGGCGCAGCTTTCGGGCATGGAAGCGCGGTGAGAAGGTGAGCGACGAA
ATCGTCAGCGGCGGCGGGGTGATGAGCTGGCTGTTTGGCAAGACCTTCCGTCTGATAAGCCGCAGCTGGCAGATGTACCT
GGTCGGGTTCCTGTTTGGCCTCGGTTTTGATACCGCCACCGAAATCGGCGTACTGGGTATCTCCGCCGCCGGCGCGTCGA
GCGGGATTTCCGTCTGGTCGATTATGGTCTTTCCGGCGCTGTTCGCCAGCGGTATGGCGCTGGTGGATACGCTTGATAAT
GTGCTGATGGTCGGCGCCTACGGCTGGGCGTTCAGCAAGCCGCAGCGCAAGCTCTATTACAATATGACCATCACCGGTAC
CTCGGTGGTGGTAGCGCTGTTTATCGGCGGCCTGGAAGCGCTGGGTCTGCTGATGGATAAGTTTGCGCTCAGCGGCGGAA
TATGGCGCTGGGTAGGGGCGTTAAACGACAACCTTGGCGACGCCGGATTTGTGGTGGTCGGGTTGTTTGTCGCCTGTTGG
GCGCTATCGGTGCTTAACTATCGCTGGCGCGGCTACGACAATCTAGCGCGCTAG

Upstream 100 bases:

>100_bases
CTCTGCTGTTTGCACAGCAGTTGCCGGCCGGCGACGGCGCAATCGCCTATGGTCAGGCGGTGATCGCCGCCGCCCGCGGG
CAGGCTCAAGGAATAAAACC

Downstream 100 bases:

>100_bases
GCTGGATATGTTCCCGGCTTGCGCTGCGCTTAGCCGGGCTACCAGGACAATACCGTAGCCCGGCTAAGGCGTTTACGCCG
CAAGCCGGGAAAACCATCAA

Product: putative high-affinity nickel-transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MIMTVLRQQPRAAGLVLGLIAANLLAWCWALQAFGDSGALMAASLLAWGYGLRHAVDADHIAAIDNVTRKMMQQGRRPFA
VGAWFSLGHSSIVVLASAAIAATATAFSTQMSWLHDTGSVIGTAVSALFLLAMAFINLVILRSVWRSFRAWKRGEKVSDE
IVSGGGVMSWLFGKTFRLISRSWQMYLVGFLFGLGFDTATEIGVLGISAAGASSGISVWSIMVFPALFASGMALVDTLDN
VLMVGAYGWAFSKPQRKLYYNMTITGTSVVVALFIGGLEALGLLMDKFALSGGIWRWVGALNDNLGDAGFVVVGLFVACW
ALSVLNYRWRGYDNLAR

Sequences:

>Translated_337_residues
MIMTVLRQQPRAAGLVLGLIAANLLAWCWALQAFGDSGALMAASLLAWGYGLRHAVDADHIAAIDNVTRKMMQQGRRPFA
VGAWFSLGHSSIVVLASAAIAATATAFSTQMSWLHDTGSVIGTAVSALFLLAMAFINLVILRSVWRSFRAWKRGEKVSDE
IVSGGGVMSWLFGKTFRLISRSWQMYLVGFLFGLGFDTATEIGVLGISAAGASSGISVWSIMVFPALFASGMALVDTLDN
VLMVGAYGWAFSKPQRKLYYNMTITGTSVVVALFIGGLEALGLLMDKFALSGGIWRWVGALNDNLGDAGFVVVGLFVACW
ALSVLNYRWRGYDNLAR
>Mature_337_residues
MIMTVLRQQPRAAGLVLGLIAANLLAWCWALQAFGDSGALMAASLLAWGYGLRHAVDADHIAAIDNVTRKMMQQGRRPFA
VGAWFSLGHSSIVVLASAAIAATATAFSTQMSWLHDTGSVIGTAVSALFLLAMAFINLVILRSVWRSFRAWKRGEKVSDE
IVSGGGVMSWLFGKTFRLISRSWQMYLVGFLFGLGFDTATEIGVLGISAAGASSGISVWSIMVFPALFASGMALVDTLDN
VLMVGAYGWAFSKPQRKLYYNMTITGTSVVVALFIGGLEALGLLMDKFALSGGIWRWVGALNDNLGDAGFVVVGLFVACW
ALSVLNYRWRGYDNLAR

Specific function: High-affinity nickel transporter responsible for nickel uptake. Necessary for high levels of activity of hydrogenase and urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 36258; Mature: 36258

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMTVLRQQPRAAGLVLGLIAANLLAWCWALQAFGDSGALMAASLLAWGYGLRHAVDADH
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHH
IAAIDNVTRKMMQQGRRPFAVGAWFSLGHSSIVVLASAAIAATATAFSTQMSWLHDTGSV
HHHHHHHHHHHHHCCCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGTAVSALFLLAMAFINLVILRSVWRSFRAWKRGEKVSDEIVSGGGVMSWLFGKTFRLIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHH
RSWQMYLVGFLFGLGFDTATEIGVLGISAAGASSGISVWSIMVFPALFASGMALVDTLDN
HHHHHHHHHHHHHCCCCCHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
VLMVGAYGWAFSKPQRKLYYNMTITGTSVVVALFIGGLEALGLLMDKFALSGGIWRWVGA
HHHHHCCCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LNDNLGDAGFVVVGLFVACWALSVLNYRWRGYDNLAR
HCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCC
>Mature Secondary Structure
MIMTVLRQQPRAAGLVLGLIAANLLAWCWALQAFGDSGALMAASLLAWGYGLRHAVDADH
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHH
IAAIDNVTRKMMQQGRRPFAVGAWFSLGHSSIVVLASAAIAATATAFSTQMSWLHDTGSV
HHHHHHHHHHHHHCCCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGTAVSALFLLAMAFINLVILRSVWRSFRAWKRGEKVSDEIVSGGGVMSWLFGKTFRLIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHH
RSWQMYLVGFLFGLGFDTATEIGVLGISAAGASSGISVWSIMVFPALFASGMALVDTLDN
HHHHHHHHHHHHHCCCCCHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
VLMVGAYGWAFSKPQRKLYYNMTITGTSVVVALFIGGLEALGLLMDKFALSGGIWRWVGA
HHHHHCCCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LNDNLGDAGFVVVGLFVACWALSVLNYRWRGYDNLAR
HCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1847142; 7896709; 12948488; 7934894 [H]