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The map label for this gene is mntH [H]

Identifier: 238895874

GI number: 238895874

Start: 3819345

End: 3820586

Strand: Reverse

Name: mntH [H]

Synonym: KP1_3996

Alternate gene names: 238895874

Gene position: 3820586-3819345 (Counterclockwise)

Preceding gene: 238895876

Following gene: 238895871

Centisome position: 72.79

GC content: 58.37

Gene sequence:

>1242_bases
ATGACTAGCAGTCGCGTTGAGAATAGCAGTAGTCGCGCCGCGCGCAAGGTGAAGCTCGCCTTAATGGGCCCGGCTTTCGT
CGCTGCCATTGGCTATATCGATCCGGGTAATTTCGCCACTAACATTCAGGCCGGCGCCAGCTTTGGCTACCAGCTGCTGT
GGGTCGTGGTGTGGGCTAACCTGATGGCGATGCTGATCCAGGTGCTTTCTGCCAAACTGGGCATTGCCACCGGCAAAAAC
CTGGCCGAGCAGATCCGCGACCATTACCCGCGTCCTGTTGTCTGGTTTTACTGGGTACAGGCGGAAATTATCGCTATGGC
CACCGATCTGGCTGAATTTATCGGCGCCGCAATTGGTTTTAAGCTGGTACTCGGCGTATCGCTTCTGCAGGGGGCGGTGC
TGACCGGGGTGGCGACTTTTCTGATCCTGATGCTGCAGCGGCGCGGGCAAAAACCACTGGAGAAGGTGATCGGTGGATTG
TTGCTGTTTGTCGCCGTGGCCTATGTCGTGGAGTTGATCTTTTCCCAGCCCGCGCTGGCTCCTCTGACGAAAGGACTGGT
GATCCCCACGCTGCCCAACGGGGAGGCGGTATTCTTAGCCGCCGGGGTACTGGGGGCGACAATCATGCCGCACGTTATCT
ACTTACATTCCTCGCTTACCCAGCATCTGCATGGCGGAACGCGAAAAGAACGCTATAACGCGACCCGCTGGGATGTGGCG
ATCGCCATGACCATTGCCGGGTTCGTCAATCTGGCGATGATGGCGACCGCTGCGGCGGCATTCCACTTTAATGGCCATAC
CGGCGTCGCCGATCTTGATCAGGCCTACATGACGCTGGAGCCGCTGCTGAGCCACGCGGCGGCGACCATCTTTGGCCTCA
GCCTGATTGCCGCCGGTTTATCGTCGACCGTGGTGGGCACTCTGGCAGGTCAGGTCGTTATGCAGGGGTTTATCCGCTTT
CATATTCCGCTGTGGTTTCGCCGGGCGATCACCATGCTGCCGTCGTTTGTCGTCATTCTGCTGGGGCTGGATCCTACGCG
CATCCTGGTAATGAGTCAGGTGTTGCTCAGCTTTGGCATTGCGCTTGCCCTGGTGCCGCTGCTGATATTTACCAGCAATG
CGAAGCTGATGGGGGACCTGGTGAATACCCGTTGGGTGAGAGGCATCGGCTGGGCGATAGTCGCTATTGTGGTGAGCCTG
AACGGCTGGTTAATAGTGGGGTCGCTGCTCGGGGTGGATTAA

Upstream 100 bases:

>100_bases
CTATCACAGCAATCATTATCTCCATTCTAAATGAACTTGATAATCATTCGCATTTTGATAGCATGAAACATAGCAAAGGC
TATATTTCCAGAGGCAGAAG

Downstream 100 bases:

>100_bases
TTGATTCCTGATGCTGAATAAAGTAAAGGGGAGCCGATGGGCTCCCCTTTTCGTTTGTTAGTGATGGCCATGTCCATGAC
CGTGACCGCGCCCGCCCGGG

Product: manganese transport protein MntH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MTSSRVENSSSRAARKVKLALMGPAFVAAIGYIDPGNFATNIQAGASFGYQLLWVVVWANLMAMLIQVLSAKLGIATGKN
LAEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGFKLVLGVSLLQGAVLTGVATFLILMLQRRGQKPLEKVIGGL
LLFVAVAYVVELIFSQPALAPLTKGLVIPTLPNGEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGTRKERYNATRWDVA
IAMTIAGFVNLAMMATAAAAFHFNGHTGVADLDQAYMTLEPLLSHAAATIFGLSLIAAGLSSTVVGTLAGQVVMQGFIRF
HIPLWFRRAITMLPSFVVILLGLDPTRILVMSQVLLSFGIALALVPLLIFTSNAKLMGDLVNTRWVRGIGWAIVAIVVSL
NGWLIVGSLLGVD

Sequences:

>Translated_413_residues
MTSSRVENSSSRAARKVKLALMGPAFVAAIGYIDPGNFATNIQAGASFGYQLLWVVVWANLMAMLIQVLSAKLGIATGKN
LAEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGFKLVLGVSLLQGAVLTGVATFLILMLQRRGQKPLEKVIGGL
LLFVAVAYVVELIFSQPALAPLTKGLVIPTLPNGEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGTRKERYNATRWDVA
IAMTIAGFVNLAMMATAAAAFHFNGHTGVADLDQAYMTLEPLLSHAAATIFGLSLIAAGLSSTVVGTLAGQVVMQGFIRF
HIPLWFRRAITMLPSFVVILLGLDPTRILVMSQVLLSFGIALALVPLLIFTSNAKLMGDLVNTRWVRGIGWAIVAIVVSL
NGWLIVGSLLGVD
>Mature_412_residues
TSSRVENSSSRAARKVKLALMGPAFVAAIGYIDPGNFATNIQAGASFGYQLLWVVVWANLMAMLIQVLSAKLGIATGKNL
AEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGFKLVLGVSLLQGAVLTGVATFLILMLQRRGQKPLEKVIGGLL
LFVAVAYVVELIFSQPALAPLTKGLVIPTLPNGEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGTRKERYNATRWDVAI
AMTIAGFVNLAMMATAAAAFHFNGHTGVADLDQAYMTLEPLLSHAAATIFGLSLIAAGLSSTVVGTLAGQVVMQGFIRFH
IPLWFRRAITMLPSFVVILLGLDPTRILVMSQVLLSFGIALALVPLLIFTSNAKLMGDLVNTRWVRGIGWAIVAIVVSLN
GWLIVGSLLGVD

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=429, Percent_Identity=32.4009324009324, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI295293178, Length=444, Percent_Identity=30.6306306306306, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI295293175, Length=444, Percent_Identity=30.6306306306306, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI295293173, Length=444, Percent_Identity=30.6306306306306, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI10835169, Length=444, Percent_Identity=30.6306306306306, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI295293171, Length=444, Percent_Identity=30.6306306306306, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI295293169, Length=444, Percent_Identity=30.6306306306306, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI295293167, Length=444, Percent_Identity=30.6306306306306, Blast_Score=162, Evalue=6e-40,
Organism=Escherichia coli, GI1788736, Length=412, Percent_Identity=87.378640776699, Blast_Score=716, Evalue=0.0,
Organism=Caenorhabditis elegans, GI193210616, Length=440, Percent_Identity=31.1363636363636, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17569473, Length=372, Percent_Identity=30.1075268817204, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI71999499, Length=460, Percent_Identity=28.2608695652174, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI71993856, Length=220, Percent_Identity=37.2727272727273, Blast_Score=141, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6323062, Length=458, Percent_Identity=32.3144104803493, Blast_Score=192, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6324450, Length=415, Percent_Identity=29.8795180722892, Blast_Score=172, Evalue=9e-44,
Organism=Saccharomyces cerevisiae, GI6321841, Length=401, Percent_Identity=30.6733167082294, Blast_Score=160, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24648607, Length=424, Percent_Identity=31.8396226415094, Blast_Score=202, Evalue=2e-52,
Organism=Drosophila melanogaster, GI281362176, Length=424, Percent_Identity=31.8396226415094, Blast_Score=202, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24648609, Length=424, Percent_Identity=31.8396226415094, Blast_Score=202, Evalue=2e-52,
Organism=Drosophila melanogaster, GI45553443, Length=406, Percent_Identity=32.0197044334975, Blast_Score=199, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 44195; Mature: 44064

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSRVENSSSRAARKVKLALMGPAFVAAIGYIDPGNFATNIQAGASFGYQLLWVVVWAN
CCCCCCCCCHHHHHHHHHHEEECHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LMAMLIQVLSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
KLVLGVSLLQGAVLTGVATFLILMLQRRGQKPLEKVIGGLLLFVAVAYVVELIFSQPALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
PLTKGLVIPTLPNGEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGTRKERYNATRWDVA
HHHCCCEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHH
IAMTIAGFVNLAMMATAAAAFHFNGHTGVADLDQAYMTLEPLLSHAAATIFGLSLIAAGL
HHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSTVVGTLAGQVVMQGFIRFHIPLWFRRAITMLPSFVVILLGLDPTRILVMSQVLLSFGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ALALVPLLIFTSNAKLMGDLVNTRWVRGIGWAIVAIVVSLNGWLIVGSLLGVD
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHCCC
>Mature Secondary Structure 
TSSRVENSSSRAARKVKLALMGPAFVAAIGYIDPGNFATNIQAGASFGYQLLWVVVWAN
CCCCCCCCHHHHHHHHHHEEECHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LMAMLIQVLSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
KLVLGVSLLQGAVLTGVATFLILMLQRRGQKPLEKVIGGLLLFVAVAYVVELIFSQPALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
PLTKGLVIPTLPNGEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGTRKERYNATRWDVA
HHHCCCEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHH
IAMTIAGFVNLAMMATAAAAFHFNGHTGVADLDQAYMTLEPLLSHAAATIFGLSLIAAGL
HHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSTVVGTLAGQVVMQGFIRFHIPLWFRRAITMLPSFVVILLGLDPTRILVMSQVLLSFGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ALALVPLLIFTSNAKLMGDLVNTRWVRGIGWAIVAIVVSLNGWLIVGSLLGVD
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA