Click here to switch to the map view.

The map label for this gene is menC [H]

Identifier: 238895786

GI number: 238895786

Start: 3731262

End: 3732227

Strand: Reverse

Name: menC [H]

Synonym: KP1_3900

Alternate gene names: 238895786

Gene position: 3732227-3731262 (Counterclockwise)

Preceding gene: 238895787

Following gene: 238895785

Centisome position: 71.11

GC content: 64.91

Gene sequence:

>966_bases
ATGCGCGTTTCGCAGGTTTACCGCTGGCAGATACCGATGGACGCGGGCGTGGTGCTGCGCGAGCGGCGGTTAAAAACCCG
CGACGGGCTGTTCATCCGCCTGCAGGAGGGGGAACGCGAAGGCTGGGGCGAAATTTCTCCCCTGCCGGGATTCAGTGTCG
AGACGCTGGAAGAGGCGCAAATGGCGCTGTTAGCGTGGGCACAGGCCTGGCGCGACGGCGCCGAGCCGCCGCTTCCCACG
CAGCCCTCCGTCGCGTTTGGCATCAGCTGCGCGCAGGCGGAGCTTGGCGGCGAACTACCGCAGGCCGCGGATTATCGCGC
GGCGCCGCTCTGCTCCGGCGATCCGGATGAGCTATTCGCCAGACTGGCGGCGATGCCCGGCGAGAAGGTCGCTAAGGTCA
AAGTTGGCCTCTGGGAGGCGGTCCGCGACGGTATGGTGGTCAATCTGCTGCTGGAGGCGATCCCCGACCTGCAGCTGCGG
CTCGATGCCAACCGCGCCTGGACGCCGCTCAAAGCGCAACAGTTCGCCAAATACGTTAATCCGGCGTACCGCCAGCGCAT
TGCTTTTCTTGAAGAACCTTGCAAAACGCGGGAGGATTCTCGGGCCTTTAGCCGCGAGACAGGGATCGCTATCGCCTGGG
ATGAAAGCCTGCGCGAGGCGGATTTCTGCTTTGTCGCCGAGCCGGGGGTGCGTGCGGTGGTGATCAAACCGACGCTAACC
GGCAGTTTGCAGAAGGTGCAGCAACAGGTCGCCGCGGCGCATGCGCTGGGGTTGAGCGTAGTGATCAGCTCGTCGATCGA
GTCCAGTCTCGGCTTAACCCAGCTGGCGCGGATTGCCGCCTGGCTGACGCCGCAGACTATTCCTGGGCTGGATACGCTGG
CGCTGATGGGCGCCCAGCTGGTACGGCCGTGGCCCGAAAGTGCGCTGCCGGTGCTCAACATTGATGCGCTGGAGCCGCTG
CTGTGA

Upstream 100 bases:

>100_bases
CCACCATGCTGTTCTATATGACGGAAGAGGGGCAGGAAGGCCGCAATGCCTTCAACCAAAAACGTCAGCCGGACTTCAGC
AAATTTAAACGGAATCCATA

Downstream 100 bases:

>100_bases
CCTTTAACGACTGGCCCTGGCGGCACTGGCGTCAGCGGCGCGGAGAGGCCCTCGCCTTACGTCTGAATAACCAGCCGCTG
ACCTGGCGGGAGCTATGCGC

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MRVSQVYRWQIPMDAGVVLRERRLKTRDGLFIRLQEGEREGWGEISPLPGFSVETLEEAQMALLAWAQAWRDGAEPPLPT
QPSVAFGISCAQAELGGELPQAADYRAAPLCSGDPDELFARLAAMPGEKVAKVKVGLWEAVRDGMVVNLLLEAIPDLQLR
LDANRAWTPLKAQQFAKYVNPAYRQRIAFLEEPCKTREDSRAFSRETGIAIAWDESLREADFCFVAEPGVRAVVIKPTLT
GSLQKVQQQVAAAHALGLSVVISSSIESSLGLTQLARIAAWLTPQTIPGLDTLALMGAQLVRPWPESALPVLNIDALEPL
L

Sequences:

>Translated_321_residues
MRVSQVYRWQIPMDAGVVLRERRLKTRDGLFIRLQEGEREGWGEISPLPGFSVETLEEAQMALLAWAQAWRDGAEPPLPT
QPSVAFGISCAQAELGGELPQAADYRAAPLCSGDPDELFARLAAMPGEKVAKVKVGLWEAVRDGMVVNLLLEAIPDLQLR
LDANRAWTPLKAQQFAKYVNPAYRQRIAFLEEPCKTREDSRAFSRETGIAIAWDESLREADFCFVAEPGVRAVVIKPTLT
GSLQKVQQQVAAAHALGLSVVISSSIESSLGLTQLARIAAWLTPQTIPGLDTLALMGAQLVRPWPESALPVLNIDALEPL
L
>Mature_321_residues
MRVSQVYRWQIPMDAGVVLRERRLKTRDGLFIRLQEGEREGWGEISPLPGFSVETLEEAQMALLAWAQAWRDGAEPPLPT
QPSVAFGISCAQAELGGELPQAADYRAAPLCSGDPDELFARLAAMPGEKVAKVKVGLWEAVRDGMVVNLLLEAIPDLQLR
LDANRAWTPLKAQQFAKYVNPAYRQRIAFLEEPCKTREDSRAFSRETGIAIAWDESLREADFCFVAEPGVRAVVIKPTLT
GSLQKVQQQVAAAHALGLSVVISSSIESSLGLTQLARIAAWLTPQTIPGLDTLALMGAQLVRPWPESALPVLNIDALEPL
L

Specific function: Converts SHCHC to OSB [H]

COG id: COG1441

COG function: function code H; O-succinylbenzoate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788596, Length=321, Percent_Identity=80.9968847352025, Blast_Score=513, Evalue=1e-147,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 35170; Mature: 35170

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVSQVYRWQIPMDAGVVLRERRLKTRDGLFIRLQEGEREGWGEISPLPGFSVETLEEAQ
CCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHH
MALLAWAQAWRDGAEPPLPTQPSVAFGISCAQAELGGELPQAADYRAAPLCSGDPDELFA
HHHHHHHHHHHCCCCCCCCCCCCHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
RLAAMPGEKVAKVKVGLWEAVRDGMVVNLLLEAIPDLQLRLDANRAWTPLKAQQFAKYVN
HHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHC
PAYRQRIAFLEEPCKTREDSRAFSRETGIAIAWDESLREADFCFVAEPGVRAVVIKPTLT
HHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEECCCCCCCCEEEEECCCCEEEEECCCCC
GSLQKVQQQVAAAHALGLSVVISSSIESSLGLTQLARIAAWLTPQTIPGLDTLALMGAQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
VRPWPESALPVLNIDALEPLL
HCCCCCCCCCEEECHHHCCCC
>Mature Secondary Structure
MRVSQVYRWQIPMDAGVVLRERRLKTRDGLFIRLQEGEREGWGEISPLPGFSVETLEEAQ
CCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHH
MALLAWAQAWRDGAEPPLPTQPSVAFGISCAQAELGGELPQAADYRAAPLCSGDPDELFA
HHHHHHHHHHHCCCCCCCCCCCCHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
RLAAMPGEKVAKVKVGLWEAVRDGMVVNLLLEAIPDLQLRLDANRAWTPLKAQQFAKYVN
HHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHC
PAYRQRIAFLEEPCKTREDSRAFSRETGIAIAWDESLREADFCFVAEPGVRAVVIKPTLT
HHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEECCCCCCCCEEEEECCCCEEEEECCCCC
GSLQKVQQQVAAAHALGLSVVISSSIESSLGLTQLARIAAWLTPQTIPGLDTLALMGAQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
VRPWPESALPVLNIDALEPLL
HCCCCCCCCCEEECHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA