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The map label for this gene is dalD [H]

Identifier: 238895664

GI number: 238895664

Start: 3585403

End: 3586800

Strand: Reverse

Name: dalD [H]

Synonym: KP1_3760

Alternate gene names: 238895664

Gene position: 3586800-3585403 (Counterclockwise)

Preceding gene: 238895666

Following gene: 238895663

Centisome position: 68.34

GC content: 58.87

Gene sequence:

>1398_bases
GTGGCGCCATCAACTCAAGGAGAGCAGAACATGAACAATCAATTCACATGGCTTCATATCGGTCTGGGTTCTTTTCATCG
TGCGCATCAGGCGTGGTATCTGCATCGTCTGATTGCTTCCGGGGATAATCGCTGGCGCATCGCGGCGGGGAATATTCGCA
ACGACGCCGAGCAGGTGGTCCAGGCGCTGGCGGCGCAGGGAGGACGTTACGTCCTCGAGACCGTCAGCCCGGAAGGGGAG
CGCGAATATGAAGAGATCACCTCAATCCAGAAACTGCTACCGTGGCAGGCCGGGCTACAGCCGCTGATTAACGAAGGGGC
AAACCCGCAGACCAAAGTTATCGCCTTTACCGTGACGGAAGGGGGGTACTACCTGAACACTCGCCATCGGCTGGAAACCA
GCAACCCCGATCTGCAGGCCGACCTGCAAGGCGAGTGCAAAACCATTTACGGCACCCTCGCGCGGATCCTGGAAAAGCGC
ATGGCCGACAACGCCGGGCCGCTGACCCTGCTCAACTGCGATAACGTGCGCCATAACGGCGAGCGTTTCCACGACGGTAT
GGTCGAGTTCCTGCAGCTCACCGGCAAACAGGCGGTGATTGACTGGATGGCGGCCAATACCACCTGTCCGAACACCATGG
TGGACCGCATCACCCCGCGTCCGGCGGCCGATCTGCCGGCCCGCATCAAAGCGCAAACCGGAATTGATGACAAAGCGCCG
GTGATGGGGGAGACCTTTATCCAGTGGGTAGTGGAGAACAACTTCCGCGATGCCCGCCCGAATCTGGAGGCGGTCGGCGT
GGAGATGGTGGAGTCGGTCATCCCGTATGAAGAGGCGAAAATCCGTATTTTGAACTCGTCGCACAGCTGCATTGCCTGGG
CGGGAACCTTAATCGGCCAGCAGTATATTCATGAAAGCACGCTGACCGATGTTATCTACGCCATTGCCGACCGCTACGTT
ACGGAGGACGTTATTCCGTGTCTCGGCGACAACGGTATTGATCTGCCGACCTACCGGGATGTGGTGCTTAAGCGCTTTAC
CAACCCCTATATCCAGGACACCAACCAGCGCGTCGCCGCCGACGGTTTCTCGAAAATTCCGGCGATGATCGCGCCAACCT
TGCAGGAGTGCTACCAGCGCGGCGTCCGCCCGGAAGCGACCGCCATGCTGCCGGCGCTGTTCTTCGTCTTTATGGAGCAG
TGGCACAAGGGAACTCTGCCGTATCAGTACCAGGACGGCATCCTGGATGCGCAGGCGGTGCATGAGATGTTCGAGGCTCA
GGATCCGGTGGCTGTCTACGCGCGCGATAAAGCCCTGTTTGGTGATCTCGCCAACAACGCGGATTTCCTGGCGCTGATGC
GCGAGAAAGTCGCCGCCGTTTACACGCTGATTAACTAA

Upstream 100 bases:

>100_bases
AACTGGCAAGCTTTTGCTCTTTACTGGTCATTTGTAATTTAATTGGGTAATTGCTCTTTTGTGATCCATGGCTCTTATTT
TGGTCAAATGATCAATTACA

Downstream 100 bases:

>100_bases
GAGGTGGCTATGTATCTGGGTATCGATCTCGGCACATCGGAAGTCAAAGCGCTGGTCATTGATGAGAACCATGAGGTTAT
CGCCAGCCATAGCGCGCCGC

Product: D-arabinitol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MAPSTQGEQNMNNQFTWLHIGLGSFHRAHQAWYLHRLIASGDNRWRIAAGNIRNDAEQVVQALAAQGGRYVLETVSPEGE
REYEEITSIQKLLPWQAGLQPLINEGANPQTKVIAFTVTEGGYYLNTRHRLETSNPDLQADLQGECKTIYGTLARILEKR
MADNAGPLTLLNCDNVRHNGERFHDGMVEFLQLTGKQAVIDWMAANTTCPNTMVDRITPRPAADLPARIKAQTGIDDKAP
VMGETFIQWVVENNFRDARPNLEAVGVEMVESVIPYEEAKIRILNSSHSCIAWAGTLIGQQYIHESTLTDVIYAIADRYV
TEDVIPCLGDNGIDLPTYRDVVLKRFTNPYIQDTNQRVAADGFSKIPAMIAPTLQECYQRGVRPEATAMLPALFFVFMEQ
WHKGTLPYQYQDGILDAQAVHEMFEAQDPVAVYARDKALFGDLANNADFLALMREKVAAVYTLIN

Sequences:

>Translated_465_residues
MAPSTQGEQNMNNQFTWLHIGLGSFHRAHQAWYLHRLIASGDNRWRIAAGNIRNDAEQVVQALAAQGGRYVLETVSPEGE
REYEEITSIQKLLPWQAGLQPLINEGANPQTKVIAFTVTEGGYYLNTRHRLETSNPDLQADLQGECKTIYGTLARILEKR
MADNAGPLTLLNCDNVRHNGERFHDGMVEFLQLTGKQAVIDWMAANTTCPNTMVDRITPRPAADLPARIKAQTGIDDKAP
VMGETFIQWVVENNFRDARPNLEAVGVEMVESVIPYEEAKIRILNSSHSCIAWAGTLIGQQYIHESTLTDVIYAIADRYV
TEDVIPCLGDNGIDLPTYRDVVLKRFTNPYIQDTNQRVAADGFSKIPAMIAPTLQECYQRGVRPEATAMLPALFFVFMEQ
WHKGTLPYQYQDGILDAQAVHEMFEAQDPVAVYARDKALFGDLANNADFLALMREKVAAVYTLIN
>Mature_464_residues
APSTQGEQNMNNQFTWLHIGLGSFHRAHQAWYLHRLIASGDNRWRIAAGNIRNDAEQVVQALAAQGGRYVLETVSPEGER
EYEEITSIQKLLPWQAGLQPLINEGANPQTKVIAFTVTEGGYYLNTRHRLETSNPDLQADLQGECKTIYGTLARILEKRM
ADNAGPLTLLNCDNVRHNGERFHDGMVEFLQLTGKQAVIDWMAANTTCPNTMVDRITPRPAADLPARIKAQTGIDDKAPV
MGETFIQWVVENNFRDARPNLEAVGVEMVESVIPYEEAKIRILNSSHSCIAWAGTLIGQQYIHESTLTDVIYAIADRYVT
EDVIPCLGDNGIDLPTYRDVVLKRFTNPYIQDTNQRVAADGFSKIPAMIAPTLQECYQRGVRPEATAMLPALFFVFMEQW
HKGTLPYQYQDGILDAQAVHEMFEAQDPVAVYARDKALFGDLANNADFLALMREKVAAVYTLIN

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1790779, Length=444, Percent_Identity=30.6306306306306, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1787823, Length=445, Percent_Identity=30.3370786516854, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1788497, Length=354, Percent_Identity=31.3559322033898, Blast_Score=184, Evalue=9e-48,
Organism=Escherichia coli, GI48994885, Length=370, Percent_Identity=22.7027027027027, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790028, Length=225, Percent_Identity=26.6666666666667, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6324401, Length=454, Percent_Identity=31.9383259911894, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6320765, Length=454, Percent_Identity=31.9383259911894, Blast_Score=221, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: =1.1.1.11 [H]

Molecular weight: Translated: 52101; Mature: 51969

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPSTQGEQNMNNQFTWLHIGLGSFHRAHQAWYLHRLIASGDNRWRIAAGNIRNDAEQVV
CCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHH
QALAAQGGRYVLETVSPEGEREYEEITSIQKLLPWQAGLQPLINEGANPQTKVIAFTVTE
HHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHCCHHHHHCCCCCCEEEEEEEEEC
GGYYLNTRHRLETSNPDLQADLQGECKTIYGTLARILEKRMADNAGPLTLLNCDNVRHNG
CCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
ERFHDGMVEFLQLTGKQAVIDWMAANTTCPNTMVDRITPRPAADLPARIKAQTGIDDKAP
HHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCEECCCCCCCCCC
VMGETFIQWVVENNFRDARPNLEAVGVEMVESVIPYEEAKIRILNSSHSCIAWAGTLIGQ
CHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHH
QYIHESTLTDVIYAIADRYVTEDVIPCLGDNGIDLPTYRDVVLKRFTNPYIQDTNQRVAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHCCCCCHHH
DGFSKIPAMIAPTLQECYQRGVRPEATAMLPALFFVFMEQWHKGTLPYQYQDGILDAQAV
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHH
HEMFEAQDPVAVYARDKALFGDLANNADFLALMREKVAAVYTLIN
HHHHHCCCCEEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
APSTQGEQNMNNQFTWLHIGLGSFHRAHQAWYLHRLIASGDNRWRIAAGNIRNDAEQVV
CCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHH
QALAAQGGRYVLETVSPEGEREYEEITSIQKLLPWQAGLQPLINEGANPQTKVIAFTVTE
HHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHCCHHHHHCCCCCCEEEEEEEEEC
GGYYLNTRHRLETSNPDLQADLQGECKTIYGTLARILEKRMADNAGPLTLLNCDNVRHNG
CCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
ERFHDGMVEFLQLTGKQAVIDWMAANTTCPNTMVDRITPRPAADLPARIKAQTGIDDKAP
HHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCEECCCCCCCCCC
VMGETFIQWVVENNFRDARPNLEAVGVEMVESVIPYEEAKIRILNSSHSCIAWAGTLIGQ
CHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHH
QYIHESTLTDVIYAIADRYVTEDVIPCLGDNGIDLPTYRDVVLKRFTNPYIQDTNQRVAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHCCCCCHHH
DGFSKIPAMIAPTLQECYQRGVRPEATAMLPALFFVFMEQWHKGTLPYQYQDGILDAQAV
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHH
HEMFEAQDPVAVYARDKALFGDLANNADFLALMREKVAAVYTLIN
HHHHHCCCCEEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9639934 [H]