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The map label for this gene is rbtR [H]

Identifier: 238895666

GI number: 238895666

Start: 3587941

End: 3588960

Strand: Reverse

Name: rbtR [H]

Synonym: KP1_3762

Alternate gene names: 238895666

Gene position: 3588960-3587941 (Counterclockwise)

Preceding gene: 238895670

Following gene: 238895664

Centisome position: 68.38

GC content: 59.31

Gene sequence:

>1020_bases
GTGACGCAAGTTGGAAAAATGAAGAAGATAACGATTTACGACCTGGCGGAACTTTCCGGCGTTTCGGCGAGCGCGGTGAG
CGCTATCCTCAACGGTAACTGGAAAAAGCGCCGCATCAGCGCCAAGCTTGCGGAAAAGGTGACGCGGATTGCCGAGGAGC
AGGGCTATGCGATTAACCGTCAGGCCAGCATGCTGCGCAGTAAAAAATCACACGTCATCGGTATGATTATCCCCAAATAT
GATAACCGCTACTTCGGTTCCATCGCCGAACGCTTTGAGGAGATGGCCCGCGAGCGCGGCCTGCTGCCGATTATCACCTG
TACGCGCCGGCGTCCGGAACTGGAGATCGAAGCGGTAAAGGCGATGCTCTCCTGGCAGGTTGACTGGGTGGTCGCGACCG
GGGCGACCAATCCGGATAAAATTTCCGCGCTATGCCAGCAGGCGGGCGTGCCAACGGTCAATCTCGACCTGCCGGGCTCT
CTCTCGCCGTCGGTGATTTCGGATAACTACGGCGGCGCGAAAGCGTTGACTCATAAGATCCTGGCTAATAGCGCCCGCCG
CCGCGGAGAGCTGGCGCCGCTGACCTTTATCGGCGGGCGCAGCAGCGACCATAACACCAGCGAGCGTTTACGCGGCTTCC
ACGATGCGCATCGCGAGCTGGGGCTTAGCGTGCCGCAGGCGAATATTCTGGCTCCCGGCTATTCGAAAGGACACGTTGAG
GACTGCCTGCAGGAGCGGTTTGGCAGCGCGAAGACGTTGTTGCAGGGGATATTTGTTAACTCGACGATATCCCTGGAAGG
GGTTGTGCGCTGGCTGTCGCAGGTGGGTCTGACCGGCAGCGAGCAGCCGCCGATGGGCTGCTTCGACTGGGATCCTTTTG
TCTACCTGCTGGGGCACGATATCGACATGGTGCAGCAGGACGTGCCGGCGATGCTGGACGCTGTTTTTTCGATTATTGAC
GCCGGCGAAGCCAGCCAGCAGCGGATTGAAATTCCCCCGCGACTGATGAGCAGCAGCTGA

Upstream 100 bases:

>100_bases
TGCGTACTTCCTGGCGTGAAAAGGATGCTCAATCGATGAAGCTATGTTGCTCTCGCTTCATCGATTGAGCAAGTGGGGAA
ATTAACAGCGACATGATTTT

Downstream 100 bases:

>100_bases
GTCGCTGTCTGGCTGTTAAACGTTACCGCGTCAGCAGCCAGCGGGCGGTATGCTCATCGGTCACCAGGCCATTGATCCAG
CCGCCTTTAAGGGCGGCCAG

Product: regulator of gluconate (gnt) operon

Products: NA

Alternate protein names: Rbt operon repressor [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MTQVGKMKKITIYDLAELSGVSASAVSAILNGNWKKRRISAKLAEKVTRIAEEQGYAINRQASMLRSKKSHVIGMIIPKY
DNRYFGSIAERFEEMARERGLLPIITCTRRRPELEIEAVKAMLSWQVDWVVATGATNPDKISALCQQAGVPTVNLDLPGS
LSPSVISDNYGGAKALTHKILANSARRRGELAPLTFIGGRSSDHNTSERLRGFHDAHRELGLSVPQANILAPGYSKGHVE
DCLQERFGSAKTLLQGIFVNSTISLEGVVRWLSQVGLTGSEQPPMGCFDWDPFVYLLGHDIDMVQQDVPAMLDAVFSIID
AGEASQQRIEIPPRLMSSS

Sequences:

>Translated_339_residues
MTQVGKMKKITIYDLAELSGVSASAVSAILNGNWKKRRISAKLAEKVTRIAEEQGYAINRQASMLRSKKSHVIGMIIPKY
DNRYFGSIAERFEEMARERGLLPIITCTRRRPELEIEAVKAMLSWQVDWVVATGATNPDKISALCQQAGVPTVNLDLPGS
LSPSVISDNYGGAKALTHKILANSARRRGELAPLTFIGGRSSDHNTSERLRGFHDAHRELGLSVPQANILAPGYSKGHVE
DCLQERFGSAKTLLQGIFVNSTISLEGVVRWLSQVGLTGSEQPPMGCFDWDPFVYLLGHDIDMVQQDVPAMLDAVFSIID
AGEASQQRIEIPPRLMSSS
>Mature_338_residues
TQVGKMKKITIYDLAELSGVSASAVSAILNGNWKKRRISAKLAEKVTRIAEEQGYAINRQASMLRSKKSHVIGMIIPKYD
NRYFGSIAERFEEMARERGLLPIITCTRRRPELEIEAVKAMLSWQVDWVVATGATNPDKISALCQQAGVPTVNLDLPGSL
SPSVISDNYGGAKALTHKILANSARRRGELAPLTFIGGRSSDHNTSERLRGFHDAHRELGLSVPQANILAPGYSKGHVED
CLQERFGSAKTLLQGIFVNSTISLEGVVRWLSQVGLTGSEQPPMGCFDWDPFVYLLGHDIDMVQQDVPAMLDAVFSIIDA
GEASQQRIEIPPRLMSSS

Specific function: Repressor for the genes of the ribitol operon. Binds D- ribulose as an inducer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787906, Length=349, Percent_Identity=26.0744985673352, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI48994940, Length=307, Percent_Identity=26.3843648208469, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786268, Length=126, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790715, Length=321, Percent_Identity=23.3644859813084, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790194, Length=342, Percent_Identity=24.5614035087719, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789202, Length=219, Percent_Identity=26.9406392694064, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788474, Length=185, Percent_Identity=26.4864864864865, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37204; Mature: 37073

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQVGKMKKITIYDLAELSGVSASAVSAILNGNWKKRRISAKLAEKVTRIAEEQGYAINR
CCCCCCCEEEEEEEHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEECH
QASMLRSKKSHVIGMIIPKYDNRYFGSIAERFEEMARERGLLPIITCTRRRPELEIEAVK
HHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHH
AMLSWQVDWVVATGATNPDKISALCQQAGVPTVNLDLPGSLSPSVISDNYGGAKALTHKI
HHHHHCEEEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHH
LANSARRRGELAPLTFIGGRSSDHNTSERLRGFHDAHRELGLSVPQANILAPGYSKGHVE
HHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHH
DCLQERFGSAKTLLQGIFVNSTISLEGVVRWLSQVGLTGSEQPPMGCFDWDPFVYLLGHD
HHHHHHHCCHHHHHHHHHHCCEECHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCC
IDMVQQDVPAMLDAVFSIIDAGEASQQRIEIPPRLMSSS
HHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHCCCC
>Mature Secondary Structure 
TQVGKMKKITIYDLAELSGVSASAVSAILNGNWKKRRISAKLAEKVTRIAEEQGYAINR
CCCCCCEEEEEEEHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEECH
QASMLRSKKSHVIGMIIPKYDNRYFGSIAERFEEMARERGLLPIITCTRRRPELEIEAVK
HHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHH
AMLSWQVDWVVATGATNPDKISALCQQAGVPTVNLDLPGSLSPSVISDNYGGAKALTHKI
HHHHHCEEEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHH
LANSARRRGELAPLTFIGGRSSDHNTSERLRGFHDAHRELGLSVPQANILAPGYSKGHVE
HHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHH
DCLQERFGSAKTLLQGIFVNSTISLEGVVRWLSQVGLTGSEQPPMGCFDWDPFVYLLGHD
HHHHHHHCCHHHHHHHHHHCCEECHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCC
IDMVQQDVPAMLDAVFSIIDAGEASQQRIEIPPRLMSSS
HHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3891331 [H]