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The map label for this gene is xylB [H]

Identifier: 238895663

GI number: 238895663

Start: 3583930

End: 3585393

Strand: Reverse

Name: xylB [H]

Synonym: KP1_3759

Alternate gene names: 238895663

Gene position: 3585393-3583930 (Counterclockwise)

Preceding gene: 238895664

Following gene: 238895662

Centisome position: 68.31

GC content: 64.75

Gene sequence:

>1464_bases
ATGTATCTGGGTATCGATCTCGGCACATCGGAAGTCAAAGCGCTGGTCATTGATGAGAACCATGAGGTTATCGCCAGCCA
TAGCGCGCCGCTGAGTATTCAGCGGCCTCATCCGCACTGGTCAGAACAAGCGCCGGAGCTATGGTGGGAGGCGACGGAGT
ACCTGATGGCCACGCTACGGGAAAAATGCGCCCAGCATTGGCCGGCCATTAAGGCGATTGGCCTCTCCGGGCAGATGCAC
GGCGCGGTGTTGCTGGATGCAGAGGGGGAGGCGATCCGTCCGGCCATTCTGTGGAACGACACCCGCTGCGCCGCAGAGTG
CGCCGAGCTGGAGGCGATGGCGCCGGAGCTGCATCAGGTGGCGGGCAACCTGGCGATGCCGGGCTTTACCGCGCCAAAGC
TGTTGTGGGTGCGCCGTCATGAGCCGCAGCACTTTCAGCGCACCGCCACGGTGCTGTTGCCCAAGGATTATCTGCGCTAC
CGGATGACCGGGAAGAAAGTCTCCGATATGTCGGACGCCGCCGGGACGCTGTGGCTGGACGTGGCGAAGCGCGACTGGTC
CGACGCTCTGCTGGACAAGTGCGGCTTGTCACGCAGCCAAATGCCGACGCTGGTCGAAGGCTGCGAGGTTTCCGCCACCC
TTGACCCGCAGGTGGCTGCGCGCTGGGGGCTGAACGCCTCGGTGATGGTGGCCGGGGGCGGGGGGGATAACGCGGTCAGC
GCCATTGGCGTCGGCGCGGTCTCGCCGGGAGATGCGTTTATTTCGCTCGGCACCTCCGGGGTGCTGTTTGTGGTGACCGA
CGCCTATCGTCCGGCGCCGCAGTCGGCGGTACATGCGTTTTGTCACGTGCTGCCGAACCTGTGGCACCAGATGAGCGTCA
TGCTGAGCGCCGCCAGCTGTTTGCAGTGGTTCTGCCGCCTGACCGGCACCACGGAGGTGGCGCTGCTGGCGGAGATTGCC
GAGCTAAGCGAGGAGGATAAAGCCCACGCCCCGTTCTTCCTGCCCTATCTCTCCGGGGAACGAACCCCGCATAACGATCC
TGACGCGCGCGGCATCTTCTGGGGCATGACCCACGCCAGCCTGCGCGCGCAGCTCGGCTACGCGGTGCTGGAGGGGGTGA
GCTTTGGGATCAACGACGGCCTGCAGGCATTGAAAGAGAGCGGGACGCCGATCGTGCAGTGCTCGCTGGTGGGCGGGGGC
GCCCGCAGTCCGTTCTGGGCCCAGCTGCTGGCCGATATTCTCGCTATGCCGGTGGTGACCCACAAAGGCGGAGAGACCGG
CGGCGCGCTGGGCGCGGCGCGGCTGGCCTGCCTGGCGGCGGGCAAACCCATTGCCGCGGTGTGTGAAAAACCGGAAGTCT
GGCAGACCTGGCGTGCGGATCCCATTCGCCACCACACCCTGATGCAACGCTACGCGCAGTTTAAGACCCTGTATTTAAAC
GATCTTAAATATCGGCAGCACTGA

Upstream 100 bases:

>100_bases
TAAAGCCCTGTTTGGTGATCTCGCCAACAACGCGGATTTCCTGGCGCTGATGCGCGAGAAAGTCGCCGCCGTTTACACGC
TGATTAACTAAGAGGTGGCT

Downstream 100 bases:

>100_bases
TTTTCATCATAACCGCCGCTTCGTTGCACGTCGCGGAGCGGCCACCCTGTACCCTGAAAACGAGGTCATTATGTCTATCA
ATAATAAACAGTGGCTCGGT

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MYLGIDLGTSEVKALVIDENHEVIASHSAPLSIQRPHPHWSEQAPELWWEATEYLMATLREKCAQHWPAIKAIGLSGQMH
GAVLLDAEGEAIRPAILWNDTRCAAECAELEAMAPELHQVAGNLAMPGFTAPKLLWVRRHEPQHFQRTATVLLPKDYLRY
RMTGKKVSDMSDAAGTLWLDVAKRDWSDALLDKCGLSRSQMPTLVEGCEVSATLDPQVAARWGLNASVMVAGGGGDNAVS
AIGVGAVSPGDAFISLGTSGVLFVVTDAYRPAPQSAVHAFCHVLPNLWHQMSVMLSAASCLQWFCRLTGTTEVALLAEIA
ELSEEDKAHAPFFLPYLSGERTPHNDPDARGIFWGMTHASLRAQLGYAVLEGVSFGINDGLQALKESGTPIVQCSLVGGG
ARSPFWAQLLADILAMPVVTHKGGETGGALGAARLACLAAGKPIAAVCEKPEVWQTWRADPIRHHTLMQRYAQFKTLYLN
DLKYRQH

Sequences:

>Translated_487_residues
MYLGIDLGTSEVKALVIDENHEVIASHSAPLSIQRPHPHWSEQAPELWWEATEYLMATLREKCAQHWPAIKAIGLSGQMH
GAVLLDAEGEAIRPAILWNDTRCAAECAELEAMAPELHQVAGNLAMPGFTAPKLLWVRRHEPQHFQRTATVLLPKDYLRY
RMTGKKVSDMSDAAGTLWLDVAKRDWSDALLDKCGLSRSQMPTLVEGCEVSATLDPQVAARWGLNASVMVAGGGGDNAVS
AIGVGAVSPGDAFISLGTSGVLFVVTDAYRPAPQSAVHAFCHVLPNLWHQMSVMLSAASCLQWFCRLTGTTEVALLAEIA
ELSEEDKAHAPFFLPYLSGERTPHNDPDARGIFWGMTHASLRAQLGYAVLEGVSFGINDGLQALKESGTPIVQCSLVGGG
ARSPFWAQLLADILAMPVVTHKGGETGGALGAARLACLAAGKPIAAVCEKPEVWQTWRADPIRHHTLMQRYAQFKTLYLN
DLKYRQH
>Mature_487_residues
MYLGIDLGTSEVKALVIDENHEVIASHSAPLSIQRPHPHWSEQAPELWWEATEYLMATLREKCAQHWPAIKAIGLSGQMH
GAVLLDAEGEAIRPAILWNDTRCAAECAELEAMAPELHQVAGNLAMPGFTAPKLLWVRRHEPQHFQRTATVLLPKDYLRY
RMTGKKVSDMSDAAGTLWLDVAKRDWSDALLDKCGLSRSQMPTLVEGCEVSATLDPQVAARWGLNASVMVAGGGGDNAVS
AIGVGAVSPGDAFISLGTSGVLFVVTDAYRPAPQSAVHAFCHVLPNLWHQMSVMLSAASCLQWFCRLTGTTEVALLAEIA
ELSEEDKAHAPFFLPYLSGERTPHNDPDARGIFWGMTHASLRAQLGYAVLEGVSFGINDGLQALKESGTPIVQCSLVGGG
ARSPFWAQLLADILAMPVVTHKGGETGGALGAARLACLAAGKPIAAVCEKPEVWQTWRADPIRHHTLMQRYAQFKTLYLN
DLKYRQH

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=447, Percent_Identity=24.1610738255034, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI4504007, Length=447, Percent_Identity=24.1610738255034, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI189409120, Length=447, Percent_Identity=24.1610738255034, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI41393575, Length=439, Percent_Identity=23.6902050113895, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI164663828, Length=493, Percent_Identity=22.5152129817444, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI18860918, Length=331, Percent_Identity=23.2628398791541, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1789987, Length=480, Percent_Identity=52.7083333333333, Blast_Score=478, Evalue=1e-136,
Organism=Escherichia coli, GI1790005, Length=483, Percent_Identity=25.0517598343685, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1789168, Length=454, Percent_Identity=26.2114537444934, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1790361, Length=501, Percent_Identity=23.5528942115768, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1787789, Length=510, Percent_Identity=26.078431372549, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17535599, Length=446, Percent_Identity=25.5605381165919, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17554530, Length=478, Percent_Identity=22.5941422594142, Blast_Score=90, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6321633, Length=341, Percent_Identity=27.8592375366569, Blast_Score=117, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6320314, Length=563, Percent_Identity=22.3801065719361, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17864214, Length=464, Percent_Identity=23.2758620689655, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24654573, Length=395, Percent_Identity=24.3037974683544, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI19920476, Length=321, Percent_Identity=24.9221183800623, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21356607, Length=321, Percent_Identity=22.7414330218069, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 52875; Mature: 52875

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLGIDLGTSEVKALVIDENHEVIASHSAPLSIQRPHPHWSEQAPELWWEATEYLMATLR
CEEEEECCCCCEEEEEEECCCEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
EKCAQHWPAIKAIGLSGQMHGAVLLDAEGEAIRPAILWNDTRCAAECAELEAMAPELHQV
HHHHHHCCCEEEECCCCCCCCEEEEECCCCEECCEEEECCCHHHHHHHHHHHHHHHHHHH
AGNLAMPGFTAPKLLWVRRHEPQHFQRTATVLLPKDYLRYRMTGKKVSDMSDAAGTLWLD
HCCCCCCCCCCCCEEEEECCCCHHHHHHHEEEECHHHHHHHHCCCHHHCCHHCCCEEEEE
VAKRDWSDALLDKCGLSRSQMPTLVEGCEVSATLDPQVAARWGLNASVMVAGGGGDNAVS
EHHCCHHHHHHHHHCCCCCCCCHHHHCCEEEEECCHHHHHHCCCCEEEEEEECCCCCCHH
AIGVGAVSPGDAFISLGTSGVLFVVTDAYRPAPQSAVHAFCHVLPNLWHQMSVMLSAASC
HEECCCCCCCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQWFCRLTGTTEVALLAEIAELSEEDKAHAPFFLPYLSGERTPHNDPDARGIFWGMTHAS
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECHHHH
LRAQLGYAVLEGVSFGINDGLQALKESGTPIVQCSLVGGGARSPFWAQLLADILAMPVVT
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCEE
HKGGETGGALGAARLACLAAGKPIAAVCEKPEVWQTWRADPIRHHTLMQRYAQFKTLYLN
CCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
DLKYRQH
CCHHCCC
>Mature Secondary Structure
MYLGIDLGTSEVKALVIDENHEVIASHSAPLSIQRPHPHWSEQAPELWWEATEYLMATLR
CEEEEECCCCCEEEEEEECCCEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
EKCAQHWPAIKAIGLSGQMHGAVLLDAEGEAIRPAILWNDTRCAAECAELEAMAPELHQV
HHHHHHCCCEEEECCCCCCCCEEEEECCCCEECCEEEECCCHHHHHHHHHHHHHHHHHHH
AGNLAMPGFTAPKLLWVRRHEPQHFQRTATVLLPKDYLRYRMTGKKVSDMSDAAGTLWLD
HCCCCCCCCCCCCEEEEECCCCHHHHHHHEEEECHHHHHHHHCCCHHHCCHHCCCEEEEE
VAKRDWSDALLDKCGLSRSQMPTLVEGCEVSATLDPQVAARWGLNASVMVAGGGGDNAVS
EHHCCHHHHHHHHHCCCCCCCCHHHHCCEEEEECCHHHHHHCCCCEEEEEEECCCCCCHH
AIGVGAVSPGDAFISLGTSGVLFVVTDAYRPAPQSAVHAFCHVLPNLWHQMSVMLSAASC
HEECCCCCCCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQWFCRLTGTTEVALLAEIAELSEEDKAHAPFFLPYLSGERTPHNDPDARGIFWGMTHAS
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECHHHH
LRAQLGYAVLEGVSFGINDGLQALKESGTPIVQCSLVGGGARSPFWAQLLADILAMPVVT
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCEE
HKGGETGGALGAARLACLAAGKPIAAVCEKPEVWQTWRADPIRHHTLMQRYAQFKTLYLN
CCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
DLKYRQH
CCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6320721; 8041620; 9278503 [H]