Click here to switch to the map view.

The map label for this gene is baeS [H]

Identifier: 238895650

GI number: 238895650

Start: 3569865

End: 3571343

Strand: Direct

Name: baeS [H]

Synonym: KP1_3746

Alternate gene names: 238895650

Gene position: 3569865-3571343 (Clockwise)

Preceding gene: 238895649

Following gene: 238895651

Centisome position: 68.02

GC content: 64.57

Gene sequence:

>1479_bases
GTGAAATTTTGGCGCCCGGGTATTACCGGCAAGCTGTTCCTCGCTATATTCGCCACCTGCATCGTGCTGCTGATCAGCAT
GCACTGGGCGGTGCGCATTAGTTTTGAACGCGGGTTTATCGACTATATCAAGCGCGGCAATGAGCAACGCTTAACCATGC
TCAGCGACGCGCTGAGCGAGCAGTATGCCCAGCATGGCAGCTGGGCGTTTCTGCGCAATAATGACCGCTTTATCTTTCAG
CTGCTGCGCACCTTCGAACGGGATAACGACGACCGCTCGCCGCCGGGGCACGCCATGAAGCCGGACGCCGCCCCGGACGG
GCCGCCGCCGGATGGCCCCCCTGACGGCCCGCGCCCGAGGCCGGAAATGCCGCCCCACGGCTGGCGCACCATGTTCTGGG
TGGTGGATCAGTCGGGGCGCGTGCTGGTGGGGCCGCGAGAGCGCGTCCCGGAGGATGGTACCCAGCGCAGCATCGTGGTC
AACGGCGCGGAGGTGGGCAAAGTGATCGCCTCGCCGGTAGAGCGGCTGACGCGCAATACCGACATTAACTTCGACCGGCA
GCAAAAGCGCACCAGCTGGCTGATTGTCGCCCTTGCCACCCTGCTTGCCGCGCTGGCCACTTTCCCGTTGGCCCGCGGTC
TGCTGGCGCCGGTGAAGCGGCTGGTGGAAGGCACCCATAAGCTGGCGGCGGGCGACTTTTCCACCCGCGTGACGGTGACC
GGCGGCGATGAGCTCGGCCGCCTGGCGCAGGATTTTAACCAGCTCGCCAGCACCCTGGAGCGCAACCAGCAGATGCGTCG
CGATCTGATGGCCGATATCTCCCATGAGCTGCGTACCCCGCTGGCGGTGCTGCGCGGCGAGCTGGAGGCGATTCAGGACG
GGGTCCGGCGCTTTACCCCCGAGTCGATTCCTTCTCTGCAGGCCGAGGTGGCTACCCTCACCAAGCTGGTGGACGACCTC
CATCAGCTGTCGATGTCCGACGAGGGGGCGCTGGCCTACCAGAAAACCTCACTGGATATCATCACCCTGCTGGAAGTGGC
GGCGGGCGCTTTTCGCGAGCGCTTCGCCAGCCGGCAGCTAAGCATTCAGGTGTCGCTCCCGGAGCAGGCGATGATCTTCG
GCGACCGCGACCGCCTGATGCAGCTCTTCAACAATCTGCTGGAGAACAGCCTGCGCTATACCGACAGCGGCGGCAGCCTG
CACATCACCGCCCGCCGCAGCGGTCGCATGCTGGTGATTGACTTCGCCGACAGCGCCCCCGGCGTCAGCGATGAGCAGCT
GGCCCGCCTGTGCGAACGCTTTTACCGGGCGGAAGGATCGCGCAACCGCGCCAGCGGCGGCTCCGGCCTCGGACTGGCGA
TTTGCCTCAATATCGTAGCGGCCCACGGCGGCACCCTGCGTGCCGACCATTCGCCTTTTGGCGGGGTTAGCATTAAAGTT
GAGTTACCTCTGGAACATGATTTACCGAGAGACGTATGA

Upstream 100 bases:

>100_bases
GCATGGCGGCGATCATCGCCCTGCCGGCGCTCATCTTTTCCAGGGTACCGGATGACGTCGGCAGCAATATCGTCCTCCGT
CGACGCAACAGGAGTGGATC

Downstream 100 bases:

>100_bases
CTGAATTGCCTGTAGATGAAAACACCCCACGCATCCTTATCGTGGAAGATGAACCGAAGCTCGGCCAACTGCTGATTGAT
TATCTGCAGGCCGCCGGCTA

Product: signal transduction histidine-protein kinase BaeS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIKRGNEQRLTMLSDALSEQYAQHGSWAFLRNNDRFIFQ
LLRTFERDNDDRSPPGHAMKPDAAPDGPPPDGPPDGPRPRPEMPPHGWRTMFWVVDQSGRVLVGPRERVPEDGTQRSIVV
NGAEVGKVIASPVERLTRNTDINFDRQQKRTSWLIVALATLLAALATFPLARGLLAPVKRLVEGTHKLAAGDFSTRVTVT
GGDELGRLAQDFNQLASTLERNQQMRRDLMADISHELRTPLAVLRGELEAIQDGVRRFTPESIPSLQAEVATLTKLVDDL
HQLSMSDEGALAYQKTSLDIITLLEVAAGAFRERFASRQLSIQVSLPEQAMIFGDRDRLMQLFNNLLENSLRYTDSGGSL
HITARRSGRMLVIDFADSAPGVSDEQLARLCERFYRAEGSRNRASGGSGLGLAICLNIVAAHGGTLRADHSPFGGVSIKV
ELPLEHDLPRDV

Sequences:

>Translated_492_residues
MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIKRGNEQRLTMLSDALSEQYAQHGSWAFLRNNDRFIFQ
LLRTFERDNDDRSPPGHAMKPDAAPDGPPPDGPPDGPRPRPEMPPHGWRTMFWVVDQSGRVLVGPRERVPEDGTQRSIVV
NGAEVGKVIASPVERLTRNTDINFDRQQKRTSWLIVALATLLAALATFPLARGLLAPVKRLVEGTHKLAAGDFSTRVTVT
GGDELGRLAQDFNQLASTLERNQQMRRDLMADISHELRTPLAVLRGELEAIQDGVRRFTPESIPSLQAEVATLTKLVDDL
HQLSMSDEGALAYQKTSLDIITLLEVAAGAFRERFASRQLSIQVSLPEQAMIFGDRDRLMQLFNNLLENSLRYTDSGGSL
HITARRSGRMLVIDFADSAPGVSDEQLARLCERFYRAEGSRNRASGGSGLGLAICLNIVAAHGGTLRADHSPFGGVSIKV
ELPLEHDLPRDV
>Mature_492_residues
MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIKRGNEQRLTMLSDALSEQYAQHGSWAFLRNNDRFIFQ
LLRTFERDNDDRSPPGHAMKPDAAPDGPPPDGPPDGPRPRPEMPPHGWRTMFWVVDQSGRVLVGPRERVPEDGTQRSIVV
NGAEVGKVIASPVERLTRNTDINFDRQQKRTSWLIVALATLLAALATFPLARGLLAPVKRLVEGTHKLAAGDFSTRVTVT
GGDELGRLAQDFNQLASTLERNQQMRRDLMADISHELRTPLAVLRGELEAIQDGVRRFTPESIPSLQAEVATLTKLVDDL
HQLSMSDEGALAYQKTSLDIITLLEVAAGAFRERFASRQLSIQVSLPEQAMIFGDRDRLMQLFNNLLENSLRYTDSGGSL
HITARRSGRMLVIDFADSAPGVSDEQLARLCERFYRAEGSRNRASGGSGLGLAICLNIVAAHGGTLRADHSPFGGVSIKV
ELPLEHDLPRDV

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=492, Percent_Identity=77.2357723577236, Blast_Score=735, Evalue=0.0,
Organism=Escherichia coli, GI1786912, Length=276, Percent_Identity=31.5217391304348, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1790346, Length=272, Percent_Identity=28.6764705882353, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1787894, Length=386, Percent_Identity=24.8704663212435, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786600, Length=283, Percent_Identity=26.5017667844523, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786783, Length=273, Percent_Identity=26.007326007326, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788279, Length=332, Percent_Identity=26.2048192771084, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI145693157, Length=261, Percent_Identity=26.4367816091954, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788713, Length=284, Percent_Identity=25.7042253521127, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1790861, Length=244, Percent_Identity=27.4590163934426, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081816, Length=252, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87082128, Length=295, Percent_Identity=25.0847457627119, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787374, Length=305, Percent_Identity=23.2786885245902, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1790436, Length=230, Percent_Identity=26.5217391304348, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789403, Length=292, Percent_Identity=28.4246575342466, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1789149, Length=231, Percent_Identity=25.1082251082251, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789808, Length=255, Percent_Identity=28.2352941176471, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788549, Length=265, Percent_Identity=25.2830188679245, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790551, Length=301, Percent_Identity=25.9136212624585, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI48994928, Length=236, Percent_Identity=22.8813559322034, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54601; Mature: 54601

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIKRGNEQRLTMLSDALSE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHCCCCHHHHHHHHHHHH
QYAQHGSWAFLRNNDRFIFQLLRTFERDNDDRSPPGHAMKPDAAPDGPPPDGPPDGPRPR
HHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PEMPPHGWRTMFWVVDQSGRVLVGPRERVPEDGTQRSIVVNGAEVGKVIASPVERLTRNT
CCCCCCCCEEEEEEECCCCCEEECCHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCC
DINFDRQQKRTSWLIVALATLLAALATFPLARGLLAPVKRLVEGTHKLAAGDFSTRVTVT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GGDELGRLAQDFNQLASTLERNQQMRRDLMADISHELRTPLAVLRGELEAIQDGVRRFTP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ESIPSLQAEVATLTKLVDDLHQLSMSDEGALAYQKTSLDIITLLEVAAGAFRERFASRQL
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEE
SIQVSLPEQAMIFGDRDRLMQLFNNLLENSLRYTDSGGSLHITARRSGRMLVIDFADSAP
EEEEECCCHHEEECCHHHHHHHHHHHHHHCCEEECCCCEEEEEEECCCCEEEEEECCCCC
GVSDEQLARLCERFYRAEGSRNRASGGSGLGLAICLNIVAAHGGTLRADHSPFGGVSIKV
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCEEEEE
ELPLEHDLPRDV
EECCCCCCCCCC
>Mature Secondary Structure
MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIKRGNEQRLTMLSDALSE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHCCCCHHHHHHHHHHHH
QYAQHGSWAFLRNNDRFIFQLLRTFERDNDDRSPPGHAMKPDAAPDGPPPDGPPDGPRPR
HHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PEMPPHGWRTMFWVVDQSGRVLVGPRERVPEDGTQRSIVVNGAEVGKVIASPVERLTRNT
CCCCCCCCEEEEEEECCCCCEEECCHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCC
DINFDRQQKRTSWLIVALATLLAALATFPLARGLLAPVKRLVEGTHKLAAGDFSTRVTVT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GGDELGRLAQDFNQLASTLERNQQMRRDLMADISHELRTPLAVLRGELEAIQDGVRRFTP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ESIPSLQAEVATLTKLVDDLHQLSMSDEGALAYQKTSLDIITLLEVAAGAFRERFASRQL
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEE
SIQVSLPEQAMIFGDRDRLMQLFNNLLENSLRYTDSGGSLHITARRSGRMLVIDFADSAP
EEEEECCCHHEEECCHHHHHHHHHHHHHHCCEEECCCCEEEEEEECCCCEEEEEECCCCC
GVSDEQLARLCERFYRAEGSRNRASGGSGLGLAICLNIVAAHGGTLRADHSPFGGVSIKV
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCEEEEE
ELPLEHDLPRDV
EECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]