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The map label for this gene is baeR [H]

Identifier: 238895651

GI number: 238895651

Start: 3571340

End: 3572062

Strand: Direct

Name: baeR [H]

Synonym: KP1_3747

Alternate gene names: 238895651

Gene position: 3571340-3572062 (Clockwise)

Preceding gene: 238895650

Following gene: 238895652

Centisome position: 68.04

GC content: 61.0

Gene sequence:

>723_bases
ATGACTGAATTGCCTGTAGATGAAAACACCCCACGCATCCTTATCGTGGAAGATGAACCGAAGCTCGGCCAACTGCTGAT
TGATTATCTGCAGGCCGCCGGCTATGCGCCTGCGTTGATTAACCACGGCGACAAGGTCCTGCCCTACGTCCGCCAGACGC
CGCCGCACCTGATCCTGCTGGATCTGATGCTGCCCGGTACCGACGGTCTGACGCTGTGCCGGGAAATTCGCCGCTTCTCC
GATGTTCCGGTGGTGATGGTGACGGCGAAAATCGAAGAGATCGACCGTTTGCTGGGGCTGGAAATAGGCGCCGACGACTA
TATCTGCAAGCCCTACAGCCCCCGGGAAGTGGTCGCCCGGGTAAAAACCATCCTCCGCCGCTGCAAGCCGCAGCGCGATC
TGCAGGCGCTGGACGCCCAGAGCCCGCTGATTGTCGACGAAGGTCGTTTTCAGGCCTCCTGGCGCGACAAGCTGCTGGAC
CTCACTCCCGCCGAGTTCCGGCTGCTGAAAACCCTCTCCCAGGAGCCGGGCAAAGTGTTCTCCCGCGAACAGCTACTCAA
CCATCTGTATGACGATTATCGGGTAGTCACCGATCGCACCATCGACAGCCACATCAAGAACCTGCGGCGCAAGCTGGAGG
CGCTGGACGCCGAGCAGTCGTTTATCCGCGCGGTGTATGGCGTTGGCTACCGCTGGGAAGCGGACGCCTGCCGGCTGGCG
TAG

Upstream 100 bases:

>100_bases
TAGCGGCCCACGGCGGCACCCTGCGTGCCGACCATTCGCCTTTTGGCGGGGTTAGCATTAAAGTTGAGTTACCTCTGGAA
CATGATTTACCGAGAGACGT

Downstream 100 bases:

>100_bases
TTAGCCTTTTCCCGGCTCGCGCTGCGCTTCGCCGGGCTACACGTTCACCGCCATCTGCAATCCGTAGCCCGGGTAAGGCG
TTTACGCCGCAACCCGGGGA

Product: DNA-binding transcriptional regulator BaeR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTELPVDENTPRILIVEDEPKLGQLLIDYLQAAGYAPALINHGDKVLPYVRQTPPHLILLDLMLPGTDGLTLCREIRRFS
DVPVVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCKPQRDLQALDAQSPLIVDEGRFQASWRDKLLD
LTPAEFRLLKTLSQEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLEALDAEQSFIRAVYGVGYRWEADACRLA

Sequences:

>Translated_240_residues
MTELPVDENTPRILIVEDEPKLGQLLIDYLQAAGYAPALINHGDKVLPYVRQTPPHLILLDLMLPGTDGLTLCREIRRFS
DVPVVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCKPQRDLQALDAQSPLIVDEGRFQASWRDKLLD
LTPAEFRLLKTLSQEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLEALDAEQSFIRAVYGVGYRWEADACRLA
>Mature_239_residues
TELPVDENTPRILIVEDEPKLGQLLIDYLQAAGYAPALINHGDKVLPYVRQTPPHLILLDLMLPGTDGLTLCREIRRFSD
VPVVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCKPQRDLQALDAQSPLIVDEGRFQASWRDKLLDL
TPAEFRLLKTLSQEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLEALDAEQSFIRAVYGVGYRWEADACRLA

Specific function: Member of the two-component regulatory system BaeS/BaeR. Activates the mdtABCD operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=240, Percent_Identity=91.6666666666667, Blast_Score=455, Evalue=1e-129,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=44, Blast_Score=174, Evalue=3e-45,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=40.625, Blast_Score=167, Evalue=5e-43,
Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=37.4468085106383, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=37.7777777777778, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=31.7596566523605, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=34.0909090909091, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=35.1931330472103, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=34.0909090909091, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=34.6666666666667, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=33.7719298245614, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=33.6283185840708, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=31.140350877193, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=30.4932735426009, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27461; Mature: 27330

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELPVDENTPRILIVEDEPKLGQLLIDYLQAAGYAPALINHGDKVLPYVRQTPPHLILL
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHCCCCCEEEE
DLMLPGTDGLTLCREIRRFSDVPVVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVAR
EEECCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCEECCCCCEECCCCHHHHHHH
VKTILRRCKPQRDLQALDAQSPLIVDEGRFQASWRDKLLDLTPAEFRLLKTLSQEPGKVF
HHHHHHHCCCHHHHHHHCCCCCEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCHHH
SREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLEALDAEQSFIRAVYGVGYRWEADACRLA
HHHHHHHHHHHHHEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHCCC
>Mature Secondary Structure 
TELPVDENTPRILIVEDEPKLGQLLIDYLQAAGYAPALINHGDKVLPYVRQTPPHLILL
CCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHCCCCCEEEE
DLMLPGTDGLTLCREIRRFSDVPVVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVAR
EEECCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCEECCCCCEECCCCHHHHHHH
VKTILRRCKPQRDLQALDAQSPLIVDEGRFQASWRDKLLDLTPAEFRLLKTLSQEPGKVF
HHHHHHHCCCHHHHHHHCCCCCEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCHHH
SREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLEALDAEQSFIRAVYGVGYRWEADACRLA
HHHHHHHHHHHHHEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]