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The map label for this gene is yegB [H]

Identifier: 238895649

GI number: 238895649

Start: 3568453

End: 3569868

Strand: Direct

Name: yegB [H]

Synonym: KP1_3745

Alternate gene names: 238895649

Gene position: 3568453-3569868 (Clockwise)

Preceding gene: 238895648

Following gene: 238895650

Centisome position: 67.99

GC content: 63.91

Gene sequence:

>1416_bases
ATGACAGACCTCCCGGCCAGCGTGCGCTGGCAGCTATGGATAGTGGCGTTCGGCTTCTTTATGCAGTCGCTGGACACCAC
CATCGTTAACACCGCCCTCCCCTCGATGGCCAAAAGCCTCGGGGAGAGTCCGCTGCATATGCATATGATTATCGTCTCCT
ATGTGTTAACGGTGGCGGTGATGCTGCCGGCCAGCGGCTGGCTGGCCGACCGGGTCGGGGTGCGCAATATCTTCTTCACC
GCCATCGTGCTGTTTACCGCCGGATCGCTGTTTTGCGCCCAGGCCAGCACCCTCGACCAGCTGGTGATGGCGCGGGTGCT
GCAGGGGGTCGGCGGCGCGATGATGGTGCCGGTCGGCCGCCTGACGGTGATGAAGATCGTCCCGCGCGATCAGTATATGG
CGGCGATGACCTTCGTTACCCTGCCGGGCCAGGTCGGCCCGCTGCTCGGCCCGGCGCTGGGCGGGGTGCTGGTGGAGTAC
GCCTCATGGCACTGGATCTTCCTCATCAACATCCCGGTGGGGATCGTCGGCGCGATCGCCACCCTCTGTCTGATGCCCAA
CTACACCATGCAGACCCGGCGCTTCGATCTCTCCGGCTTTCTGCTGCTGGCCGCCGGAATGGCGACCCTGACCCTGGCGC
TCGACGGCCAGAAAGGGCTCGGCATTTCCCCTGCCTGGCTGGCGGGGCTGGTGGCCGTCGGCCTCTGCGCCCTGCTGCTC
TACCTGTGGCACGCCCGCGGCAACGCCCGGGCGCTGTTTAGCCTTAACCTGTTTCGCAACCGCACCTTCTCTCTCGGCCT
CGGCGGCAGCTTCGCGGGACGCATCGGCAGCGGCATGCTGCCGTTTATGACCCCGGTGTTTCTGCAGATCGGCCTCGGCT
TCTCCCCCTTTCACGCCGGGCTGATGATGATCCCGATGGTGCTCGGCAGCATGGGCATGAAGCGGATCGTGGTCCAGGTG
GTCAACCGCTTTGGCTACCGTCGGGTGCTGGTCGCCAGCACCCTGGGCCTGGCGGCGGTCAGCCTGCTGTTTATGTTTAG
CGCCCTGGCCGGGTGGTATTACGTGCTGCCGCTGGTCCTGTTTCTGCAGGGGATGATCAACGCCAGCCGCTTCTCCTCAA
TGAATACCCTGACGCTGAAAGATCTCCCGGACGATCTGGCCAGCAGCGGCAACAGCCTGCTGTCGATGGTGATGCAGCTG
TCGATGAGTATCGGCGTGACCATCGCCGGGCTGCTGCTGGGGCTGTATGGCCAGCAGCATATGAGTCTCGACGCCGCCAG
CACCCATCAGGTCTTTCTCTACACCTATCTGAGCATGGCGGCGATCATCGCCCTGCCGGCGCTCATCTTTTCCAGGGTAC
CGGATGACGTCGGCAGCAATATCGTCCTCCGTCGACGCAACAGGAGTGGATCGTGA

Upstream 100 bases:

>100_bases
CAGCTGTTAACGCTCTACACCACGCCGGTGGTCTATCTTTTCTTTGACCGTCTGCGGCTGCGTTTTTCGCGTCACTCCTC
TCAACCGGTAAGCGAATAAC

Downstream 100 bases:

>100_bases
AATTTTGGCGCCCGGGTATTACCGGCAAGCTGTTCCTCGCTATATTCGCCACCTGCATCGTGCTGCTGATCAGCATGCAC
TGGGCGGTGCGCATTAGTTT

Product: multidrug efflux system protein MdtE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MTDLPASVRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMIIVSYVLTVAVMLPASGWLADRVGVRNIFFT
AIVLFTAGSLFCAQASTLDQLVMARVLQGVGGAMMVPVGRLTVMKIVPRDQYMAAMTFVTLPGQVGPLLGPALGGVLVEY
ASWHWIFLINIPVGIVGAIATLCLMPNYTMQTRRFDLSGFLLLAAGMATLTLALDGQKGLGISPAWLAGLVAVGLCALLL
YLWHARGNARALFSLNLFRNRTFSLGLGGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQV
VNRFGYRRVLVASTLGLAAVSLLFMFSALAGWYYVLPLVLFLQGMINASRFSSMNTLTLKDLPDDLASSGNSLLSMVMQL
SMSIGVTIAGLLLGLYGQQHMSLDAASTHQVFLYTYLSMAAIIALPALIFSRVPDDVGSNIVLRRRNRSGS

Sequences:

>Translated_471_residues
MTDLPASVRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMIIVSYVLTVAVMLPASGWLADRVGVRNIFFT
AIVLFTAGSLFCAQASTLDQLVMARVLQGVGGAMMVPVGRLTVMKIVPRDQYMAAMTFVTLPGQVGPLLGPALGGVLVEY
ASWHWIFLINIPVGIVGAIATLCLMPNYTMQTRRFDLSGFLLLAAGMATLTLALDGQKGLGISPAWLAGLVAVGLCALLL
YLWHARGNARALFSLNLFRNRTFSLGLGGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQV
VNRFGYRRVLVASTLGLAAVSLLFMFSALAGWYYVLPLVLFLQGMINASRFSSMNTLTLKDLPDDLASSGNSLLSMVMQL
SMSIGVTIAGLLLGLYGQQHMSLDAASTHQVFLYTYLSMAAIIALPALIFSRVPDDVGSNIVLRRRNRSGS
>Mature_470_residues
TDLPASVRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMIIVSYVLTVAVMLPASGWLADRVGVRNIFFTA
IVLFTAGSLFCAQASTLDQLVMARVLQGVGGAMMVPVGRLTVMKIVPRDQYMAAMTFVTLPGQVGPLLGPALGGVLVEYA
SWHWIFLINIPVGIVGAIATLCLMPNYTMQTRRFDLSGFLLLAAGMATLTLALDGQKGLGISPAWLAGLVAVGLCALLLY
LWHARGNARALFSLNLFRNRTFSLGLGGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQVV
NRFGYRRVLVASTLGLAAVSLLFMFSALAGWYYVLPLVLFLQGMINASRFSSMNTLTLKDLPDDLASSGNSLLSMVMQLS
MSIGVTIAGLLLGLYGQQHMSLDAASTHQVFLYTYLSMAAIIALPALIFSRVPDDVGSNIVLRRRNRSGS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI1788392, Length=471, Percent_Identity=84.5010615711253, Blast_Score=755, Evalue=0.0,
Organism=Escherichia coli, GI1790195, Length=460, Percent_Identity=46.7391304347826, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI1788710, Length=442, Percent_Identity=28.9592760180996, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1789042, Length=394, Percent_Identity=28.6802030456853, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI87081983, Length=431, Percent_Identity=27.6102088167053, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788509, Length=136, Percent_Identity=30.1470588235294, Blast_Score=63, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322958, Length=174, Percent_Identity=26.4367816091954, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323735, Length=164, Percent_Identity=29.2682926829268, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321663, Length=150, Percent_Identity=29.3333333333333, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319770, Length=282, Percent_Identity=27.3049645390071, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325455, Length=125, Percent_Identity=28, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50708; Mature: 50576

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
6.4 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLPASVRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMIIVSYVLTVAV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
MLPASGWLADRVGVRNIFFTAIVLFTAGSLFCAQASTLDQLVMARVLQGVGGAMMVPVGR
HHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
LTVMKIVPRDQYMAAMTFVTLPGQVGPLLGPALGGVLVEYASWHWIFLINIPVGIVGAIA
EEEEEECCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHHH
TLCLMPNYTMQTRRFDLSGFLLLAAGMATLTLALDGQKGLGISPAWLAGLVAVGLCALLL
HHHHCCCCCHHHHEECCCHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
YLWHARGNARALFSLNLFRNRTFSLGLGGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAG
HHHHCCCCCEEEEEEEHHHCCEEEEECCCCHHHHHCCCCHHHHHHHHHHHCCCCCHHHHH
LMMIPMVLGSMGMKRIVVQVVNRFGYRRVLVASTLGLAAVSLLFMFSALAGWYYVLPLVL
HHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLQGMINASRFSSMNTLTLKDLPDDLASSGNSLLSMVMQLSMSIGVTIAGLLLGLYGQQH
HHHHHHHHHHHCCCCEEEHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
MSLDAASTHQVFLYTYLSMAAIIALPALIFSRVPDDVGSNIVLRRRNRSGS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
TDLPASVRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMIIVSYVLTVAV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
MLPASGWLADRVGVRNIFFTAIVLFTAGSLFCAQASTLDQLVMARVLQGVGGAMMVPVGR
HHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
LTVMKIVPRDQYMAAMTFVTLPGQVGPLLGPALGGVLVEYASWHWIFLINIPVGIVGAIA
EEEEEECCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHHH
TLCLMPNYTMQTRRFDLSGFLLLAAGMATLTLALDGQKGLGISPAWLAGLVAVGLCALLL
HHHHCCCCCHHHHEECCCHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
YLWHARGNARALFSLNLFRNRTFSLGLGGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAG
HHHHCCCCCEEEEEEEHHHCCEEEEECCCCHHHHHCCCCHHHHHHHHHHHCCCCCHHHHH
LMMIPMVLGSMGMKRIVVQVVNRFGYRRVLVASTLGLAAVSLLFMFSALAGWYYVLPLVL
HHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLQGMINASRFSSMNTLTLKDLPDDLASSGNSLLSMVMQLSMSIGVTIAGLLLGLYGQQH
HHHHHHHHHHHCCCCEEEHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
MSLDAASTHQVFLYTYLSMAAIIALPALIFSRVPDDVGSNIVLRRRNRSGS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA