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The map label for this gene is virB8 [H]

Identifier: 238895550

GI number: 238895550

Start: 3455245

End: 3455928

Strand: Direct

Name: virB8 [H]

Synonym: KP1_3633

Alternate gene names: 238895550

Gene position: 3455245-3455928 (Clockwise)

Preceding gene: 238895549

Following gene: 238895551

Centisome position: 65.83

GC content: 54.09

Gene sequence:

>684_bases
ATGAGTGAACAGAAATTAATAGCTGAATCCCGCACCTTTGAGCAGCAAATGATTGAGCGGGATAAACGCGCCACTAAAGC
CGGTTTTGTTGTTGGCGGCGTGGGTCTGCTGATTGCGGTACTGGCGCTCGTCGCCGTGGTCGTGATGTTGCCGCTGAAAC
AGACGGATGTTGAGCTGTATACCGTGGATAATCATACAGGACGGGTGGAACACGTTACCCGGACATCGAAAACCAGCCTG
ACCGCAACAGAAGCCTATCAAAAGGCGATGGCCGCAAACTACGTCAAAGTGCGTGAGCGGTATGTCTATCCCTCTTTGCA
GGACGACTACGAGACGGTACAGGTCTACAACGCCCCCCAGGTAAACGATGACTACCTGGCGCTTTACGCCGGAAAAAACG
CCCCGGACAAGGTTTATAAGAACGGGGCGCACACCGTGAAAGTGGAGATCTTGTCCAACCAGATCACCGATGCGACAGCC
CCTGATAGGGTCGCCACCATCCGCTACAAGAAGATTATCCGCCGTCTGGCTGATAATAGCACCCGCAACGAATATTGGGA
TGCCCGGTTCACGTTCCATTCTGACCCTGACAAGGAAATGAGCGATGCGGAACGCGAGATCAACTACCTCGGCTTTACCG
TCACCAGCTGGCAGACCGACCGCGAAATCCGGGGAGGTGAATGA

Upstream 100 bases:

>100_bases
TGCGCGCTTTCTGGCTGCGCCCAGAACACGCCTCCCTCTGCATTTAGCGGTAAGGGAGACCCCGTAAACACCCCTCAAAT
TATGGCGGAGTTAAACAGTC

Downstream 100 bases:

>100_bases
TGAAAAAGTTAACGTTTACCGCACTGGCACTGATGATGTGCGGCGCGGCATGGGGTGCGGCCATACCGCAGGCAAGCCGC
TATGACTCCCGCGTGCAGCA

Product: type IV secretion system VirB8 component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MSEQKLIAESRTFEQQMIERDKRATKAGFVVGGVGLLIAVLALVAVVVMLPLKQTDVELYTVDNHTGRVEHVTRTSKTSL
TATEAYQKAMAANYVKVRERYVYPSLQDDYETVQVYNAPQVNDDYLALYAGKNAPDKVYKNGAHTVKVEILSNQITDATA
PDRVATIRYKKIIRRLADNSTRNEYWDARFTFHSDPDKEMSDAEREINYLGFTVTSWQTDREIRGGE

Sequences:

>Translated_227_residues
MSEQKLIAESRTFEQQMIERDKRATKAGFVVGGVGLLIAVLALVAVVVMLPLKQTDVELYTVDNHTGRVEHVTRTSKTSL
TATEAYQKAMAANYVKVRERYVYPSLQDDYETVQVYNAPQVNDDYLALYAGKNAPDKVYKNGAHTVKVEILSNQITDATA
PDRVATIRYKKIIRRLADNSTRNEYWDARFTFHSDPDKEMSDAEREINYLGFTVTSWQTDREIRGGE
>Mature_226_residues
SEQKLIAESRTFEQQMIERDKRATKAGFVVGGVGLLIAVLALVAVVVMLPLKQTDVELYTVDNHTGRVEHVTRTSKTSLT
ATEAYQKAMAANYVKVRERYVYPSLQDDYETVQVYNAPQVNDDYLALYAGKNAPDKVYKNGAHTVKVEILSNQITDATAP
DRVATIRYKKIIRRLADNSTRNEYWDARFTFHSDPDKEMSDAEREINYLGFTVTSWQTDREIRGGE

Specific function: Unknown

COG id: COG3736

COG function: function code U; Type IV secretory pathway, component VirB8

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the virB8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007430 [H]

Pfam domain/function: PF04335 VirB8 [H]

EC number: NA

Molecular weight: Translated: 25794; Mature: 25663

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQKLIAESRTFEQQMIERDKRATKAGFVVGGVGLLIAVLALVAVVVMLPLKQTDVELY
CCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
TVDNHTGRVEHVTRTSKTSLTATEAYQKAMAANYVKVRERYVYPSLQDDYETVQVYNAPQ
EECCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
VNDDYLALYAGKNAPDKVYKNGAHTVKVEILSNQITDATAPDRVATIRYKKIIRRLADNS
CCCCEEEEEECCCCCHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCC
TRNEYWDARFTFHSDPDKEMSDAEREINYLGFTVTSWQTDREIRGGE
CCCCCCCEEEEECCCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SEQKLIAESRTFEQQMIERDKRATKAGFVVGGVGLLIAVLALVAVVVMLPLKQTDVELY
CCHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
TVDNHTGRVEHVTRTSKTSLTATEAYQKAMAANYVKVRERYVYPSLQDDYETVQVYNAPQ
EECCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
VNDDYLALYAGKNAPDKVYKNGAHTVKVEILSNQITDATAPDRVATIRYKKIIRRLADNS
CCCCEEEEEECCCCCHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCC
TRNEYWDARFTFHSDPDKEMSDAEREINYLGFTVTSWQTDREIRGGE
CCCCCCCEEEEECCCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12910271; 3584073 [H]