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The map label for this gene is cbl [H]

Identifier: 238895497

GI number: 238895497

Start: 3382699

End: 3383649

Strand: Reverse

Name: cbl [H]

Synonym: KP1_3569

Alternate gene names: 238895497

Gene position: 3383649-3382699 (Counterclockwise)

Preceding gene: 238895498

Following gene: 238895496

Centisome position: 64.47

GC content: 58.78

Gene sequence:

>951_bases
GTGAACTTCCAGCAGCTGAAAATTATCCGTGAGGCGGCCCGTCAGGATTACAACCTGACGGAAGTCGCGAATATGCTCTA
TACCTCGCAGTCAGGCGTCAGTCGCCATATCCGGGAACTGGAAGAGGAGCTGGGGATTGAGATCTTTATCCGCCGCGGCA
AACGCCTGTTAGGCATGACCGAGCCGGGTAAAGCGCTGTTATCGATTGCCGAGCGGATCCTCAATGAAGCCAGTAACGTT
CGGCGGCTGGCGGATCTCTTCACTAACGATGCGTCAGGCGTCTTAACTATCGCCACCACCCATACTCAGGCGCGCTACAG
CCTGCCGCCGGTCATTAAAGCTTTCCGCGAGCTGTTCTCAGATGTTCGCGTCGAGCTGGTGCAGGGTACCCCGCAGGAAA
TCGAAGCGCTGCTGCATAACGGCGGAGCGGATATCGGCATCGCCAGCGAGCGCCTGAGCAACGATCCGACGCTGGCGGCT
TTCCCCTGGTTCCGCTGGCATCACAGCCTGCTGGTGCCGAAGGATCATCCTTTGACGCAGGTTTCTCCCCTGACGCTGGA
GGCGATCGCCCGCTGGCCGTTAATCACCTACCGCCAGGGGATCACTGGCCGTTCGCGCATTGATGAGGCGTTCAACCGCA
AGGGGTTGATGCCGGATATCGTGCTGAGCGCGCAGGATTCCGATGTGATCAAGACCTACGTGGAGCTGGGGCTGGGCGTC
GGGCTGGTCGCCGAGCAGTCCGGTGATGCCCGGGAAGCGGACACCTTTACGCGTCTTGATACACGCCATCTGTTCGATGC
CAATACCGTGTGGTTGGGACTGAAGCGGGGCCAGCTGCAGCGGAATTACGTTTGGCGCTTTATCGAATTGTGCAATGCCG
GACTGTCGCTGGATGAGATTAAGCGTCAGGCGATGGAGCCGGAAGAGGCCGCAATCGACTATCAGATTTAA

Upstream 100 bases:

>100_bases
TTCTCTTAAGGAATAAGTTGCTGGTTTTTATTATTTGTTACCTGGGACAACAGACTTTAACAATAGCAGATACGTTAAGT
CCATTGGCCCGGAGGAAAGG

Downstream 100 bases:

>100_bases
GGAAATGCTGGCCAGCGGGTCGGGGAGTGGAAATAACGCTATAATTCACACACGTGAGTCGCGACTGAGGAAGGGAAAAT
GACGATGCGGCGTGTGAAAT

Product: transcriptional regulator Cbl

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MNFQQLKIIREAARQDYNLTEVANMLYTSQSGVSRHIRELEEELGIEIFIRRGKRLLGMTEPGKALLSIAERILNEASNV
RRLADLFTNDASGVLTIATTHTQARYSLPPVIKAFRELFSDVRVELVQGTPQEIEALLHNGGADIGIASERLSNDPTLAA
FPWFRWHHSLLVPKDHPLTQVSPLTLEAIARWPLITYRQGITGRSRIDEAFNRKGLMPDIVLSAQDSDVIKTYVELGLGV
GLVAEQSGDAREADTFTRLDTRHLFDANTVWLGLKRGQLQRNYVWRFIELCNAGLSLDEIKRQAMEPEEAAIDYQI

Sequences:

>Translated_316_residues
MNFQQLKIIREAARQDYNLTEVANMLYTSQSGVSRHIRELEEELGIEIFIRRGKRLLGMTEPGKALLSIAERILNEASNV
RRLADLFTNDASGVLTIATTHTQARYSLPPVIKAFRELFSDVRVELVQGTPQEIEALLHNGGADIGIASERLSNDPTLAA
FPWFRWHHSLLVPKDHPLTQVSPLTLEAIARWPLITYRQGITGRSRIDEAFNRKGLMPDIVLSAQDSDVIKTYVELGLGV
GLVAEQSGDAREADTFTRLDTRHLFDANTVWLGLKRGQLQRNYVWRFIELCNAGLSLDEIKRQAMEPEEAAIDYQI
>Mature_316_residues
MNFQQLKIIREAARQDYNLTEVANMLYTSQSGVSRHIRELEEELGIEIFIRRGKRLLGMTEPGKALLSIAERILNEASNV
RRLADLFTNDASGVLTIATTHTQARYSLPPVIKAFRELFSDVRVELVQGTPQEIEALLHNGGADIGIASERLSNDPTLAA
FPWFRWHHSLLVPKDHPLTQVSPLTLEAIARWPLITYRQGITGRSRIDEAFNRKGLMPDIVLSAQDSDVIKTYVELGLGV
GLVAEQSGDAREADTFTRLDTRHLFDANTVWLGLKRGQLQRNYVWRFIELCNAGLSLDEIKRQAMEPEEAAIDYQI

Specific function: May be an accessory regulatory protein within the cys regulon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788296, Length=316, Percent_Identity=86.0759493670886, Blast_Score=554, Evalue=1e-159,
Organism=Escherichia coli, GI1787530, Length=300, Percent_Identity=41.6666666666667, Blast_Score=247, Evalue=8e-67,
Organism=Escherichia coli, GI1788481, Length=293, Percent_Identity=26.6211604095563, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI157672245, Length=213, Percent_Identity=28.169014084507, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI2367136, Length=245, Percent_Identity=26.1224489795918, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788887, Length=235, Percent_Identity=28.5106382978723, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693105, Length=232, Percent_Identity=25, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790208, Length=249, Percent_Identity=28.1124497991968, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87081904, Length=210, Percent_Identity=28.0952380952381, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35675; Mature: 35675

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFQQLKIIREAARQDYNLTEVANMLYTSQSGVSRHIRELEEELGIEIFIRRGKRLLGMT
CCHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCEEEEECCCCHHCCCC
EPGKALLSIAERILNEASNVRRLADLFTNDASGVLTIATTHTQARYSLPPVIKAFRELFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHH
DVRVELVQGTPQEIEALLHNGGADIGIASERLSNDPTLAAFPWFRWHHSLLVPKDHPLTQ
HHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCEEECCHHHHHCCEECCCCCCCCC
VSPLTLEAIARWPLITYRQGITGRSRIDEAFNRKGLMPDIVLSAQDSDVIKTYVELGLGV
CCCHHHHHHHHCCHHHHHCCCCCHHHHHHHHHCCCCCCHHEEECCCHHHHHHHHHHCCCC
GLVAEQSGDAREADTFTRLDTRHLFDANTVWLGLKRGQLQRNYVWRFIELCNAGLSLDEI
CEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHH
KRQAMEPEEAAIDYQI
HHHHCCCHHHCCCCCC
>Mature Secondary Structure
MNFQQLKIIREAARQDYNLTEVANMLYTSQSGVSRHIRELEEELGIEIFIRRGKRLLGMT
CCHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCEEEEECCCCHHCCCC
EPGKALLSIAERILNEASNVRRLADLFTNDASGVLTIATTHTQARYSLPPVIKAFRELFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHH
DVRVELVQGTPQEIEALLHNGGADIGIASERLSNDPTLAAFPWFRWHHSLLVPKDHPLTQ
HHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCEEECCHHHHHCCEECCCCCCCCC
VSPLTLEAIARWPLITYRQGITGRSRIDEAFNRKGLMPDIVLSAQDSDVIKTYVELGLGV
CCCHHHHHHHHCCHHHHHCCCCCHHHHHHHHHCCCCCCHHEEECCCHHHHHHHHHHCCCC
GLVAEQSGDAREADTFTRLDTRHLFDANTVWLGLKRGQLQRNYVWRFIELCNAGLSLDEI
CEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHH
KRQAMEPEEAAIDYQI
HHHHCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8458853 [H]