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The map label for this gene is pcpR [H]

Identifier: 238895337

GI number: 238895337

Start: 3221226

End: 3222152

Strand: Reverse

Name: pcpR [H]

Synonym: KP1_3397

Alternate gene names: 238895337

Gene position: 3222152-3221226 (Counterclockwise)

Preceding gene: 238895339

Following gene: 238895336

Centisome position: 61.39

GC content: 64.29

Gene sequence:

>927_bases
ATGAATATTATGCATCCTGTCCTGCGCCGGATTGACCTCAACCTGTTGCCGGTCTTTGACGCGGTCTATCGCTCCCGCTC
GGTACGCCTGGCGGCGGAAGAGCTGGCGATGAGCACCTCGGCGCTGAGCCATGCGCTTTCCCGGCTGCGCAGCGCCCTCA
ACGATCCGCTGTTCTACCGCGAAGGCCACCGGATGTGCCCCAGCGTCTATGCCAGCCAGCTGGCGCCCTCTATCGCTTCG
GCGCTGAAGTTTCTCAACCAGGAGCTGACGCCGCCGGCGGCGTTTGTGCCGGCCGCCAGCACCGACTGCATGCAGATTGC
GATCACCGATTTCACCGCGTTCTGCGTCTTTCCGACGCTGATGCATCACCTGCAGCGTGAGGCGCCCGGGCTGCGGTTTG
AGCTCCGTTATCTGCCCCACAGCCCGGCGCTGACCGAGCTGCTGGCGGGCGAGGTCGACCTGGCCCTCGGGTTCAATACC
CCTGACGAGCCAGCCCATCCCGATCTTGAGGAGATTAACTGGCTGCGGGACGAATATGTGGTCATCAGCCAGGCCAACCG
GACGGCGCTGACCCTGGACGCCTACCTTGCGGCCCGTCATCTGGTGGTGACCCCGTGGAATGAGCGGCAGGGGGTGCTGG
ACTGTGAGCTGGAGCGACAGGGCTATTCGCGGCAGGTGGCGATGAAAACCCCCTCGATGCTGAGCGCGCCCTTTATTATT
GAGCAGAGCGACCTGTTGATGGCGCTGCCCCGGCGGGCGGCGGAGACGATGGCCCGCGCCGCCCGGCTGACTATTTTCCC
GCTGCCGTTTCCGGTTCCGCCGTTTGACGTCAAGATTTACGCCCACCAACGCAGCGGGAAACGCGAGGCTACCCGCTGGC
TTATCTCCCTGTTGCAGACGCTGGTGGGGGAGTCTACCGCTTCCTGA

Upstream 100 bases:

>100_bases
ATGGGGTGTCCTGTATCCATAGTCAAAAGAGAGCAAAATTGCTGACCCTGAGGATAAGCGGTATTGTGAAAAGAATTAAG
TGCAATGAAATCAGCAAACG

Downstream 100 bases:

>100_bases
CGCGCTTTCCAGCCGGCAGCGTATATCGTTACCCCAGGCCAGGTTTTATGCCGTCAACCCACGGCGACATATCCTGGCCC
CGGTCACAAAACGGAAAACT

Product: putative LysR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNIMHPVLRRIDLNLLPVFDAVYRSRSVRLAAEELAMSTSALSHALSRLRSALNDPLFYREGHRMCPSVYASQLAPSIAS
ALKFLNQELTPPAAFVPAASTDCMQIAITDFTAFCVFPTLMHHLQREAPGLRFELRYLPHSPALTELLAGEVDLALGFNT
PDEPAHPDLEEINWLRDEYVVISQANRTALTLDAYLAARHLVVTPWNERQGVLDCELERQGYSRQVAMKTPSMLSAPFII
EQSDLLMALPRRAAETMARAARLTIFPLPFPVPPFDVKIYAHQRSGKREATRWLISLLQTLVGESTAS

Sequences:

>Translated_308_residues
MNIMHPVLRRIDLNLLPVFDAVYRSRSVRLAAEELAMSTSALSHALSRLRSALNDPLFYREGHRMCPSVYASQLAPSIAS
ALKFLNQELTPPAAFVPAASTDCMQIAITDFTAFCVFPTLMHHLQREAPGLRFELRYLPHSPALTELLAGEVDLALGFNT
PDEPAHPDLEEINWLRDEYVVISQANRTALTLDAYLAARHLVVTPWNERQGVLDCELERQGYSRQVAMKTPSMLSAPFII
EQSDLLMALPRRAAETMARAARLTIFPLPFPVPPFDVKIYAHQRSGKREATRWLISLLQTLVGESTAS
>Mature_308_residues
MNIMHPVLRRIDLNLLPVFDAVYRSRSVRLAAEELAMSTSALSHALSRLRSALNDPLFYREGHRMCPSVYASQLAPSIAS
ALKFLNQELTPPAAFVPAASTDCMQIAITDFTAFCVFPTLMHHLQREAPGLRFELRYLPHSPALTELLAGEVDLALGFNT
PDEPAHPDLEEINWLRDEYVVISQANRTALTLDAYLAARHLVVTPWNERQGVLDCELERQGYSRQVAMKTPSMLSAPFII
EQSDLLMALPRRAAETMARAARLTIFPLPFPVPPFDVKIYAHQRSGKREATRWLISLLQTLVGESTAS

Specific function: Transcriptional activator for the pcpA, pcpB and pcpE genes for pentachlorophenol (PCP) degradation. Essential for PCP degradation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=303, Percent_Identity=25.7425742574257, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI87081766, Length=268, Percent_Identity=26.865671641791, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786820, Length=83, Percent_Identity=38.5542168674699, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34475; Mature: 34475

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIMHPVLRRIDLNLLPVFDAVYRSRSVRLAAEELAMSTSALSHALSRLRSALNDPLFYR
CCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEC
EGHRMCPSVYASQLAPSIASALKFLNQELTPPAAFVPAASTDCMQIAITDFTAFCVFPTL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHH
MHHLQREAPGLRFELRYLPHSPALTELLAGEVDLALGFNTPDEPAHPDLEEINWLRDEYV
HHHHHHHCCCCEEEEEECCCCHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHCEE
VISQANRTALTLDAYLAARHLVVTPWNERQGVLDCELERQGYSRQVAMKTPSMLSAPFII
EEECCCCEEEEHHHHHHHCEEEEECCCCCCCCEEEEECCCCCCCEEEECCCCHHCCCEEE
EQSDLLMALPRRAAETMARAARLTIFPLPFPVPPFDVKIYAHQRSGKREATRWLISLLQT
ECCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
LVGESTAS
HHCCCCCC
>Mature Secondary Structure
MNIMHPVLRRIDLNLLPVFDAVYRSRSVRLAAEELAMSTSALSHALSRLRSALNDPLFYR
CCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEC
EGHRMCPSVYASQLAPSIASALKFLNQELTPPAAFVPAASTDCMQIAITDFTAFCVFPTL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHH
MHHLQREAPGLRFELRYLPHSPALTELLAGEVDLALGFNTPDEPAHPDLEEINWLRDEYV
HHHHHHHCCCCEEEEEECCCCHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHCEE
VISQANRTALTLDAYLAARHLVVTPWNERQGVLDCELERQGYSRQVAMKTPSMLSAPFII
EEECCCCEEEEHHHHHHHCEEEEECCCCCCCCEEEEECCCCCCCEEEECCCCHHCCCEEE
EQSDLLMALPRRAAETMARAARLTIFPLPFPVPPFDVKIYAHQRSGKREATRWLISLLQT
ECCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
LVGESTAS
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12169590 [H]