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The map label for this gene is rbsK [H]

Identifier: 238894744

GI number: 238894744

Start: 2627644

End: 2628588

Strand: Reverse

Name: rbsK [H]

Synonym: KP1_2751

Alternate gene names: 238894744

Gene position: 2628588-2627644 (Counterclockwise)

Preceding gene: 238894745

Following gene: 238894743

Centisome position: 50.08

GC content: 59.47

Gene sequence:

>945_bases
ATGATGTCAGGAAAAGTCTGTGTTTTTGGTTCATTCAATTTCGACATGGTCGCCAGGGTGGATCGCTTTCCGGTACCAGG
TGAGTCGTTAGTGGCCTGCGGAAGTATGACCAGCGCCGGAGGTAAAGGGGCGAACCAGGCCACCGCCGCGCTAAAAGCGG
GAGCAAATGTCCACTATATCGGCAAGATTGGCAATGACACCTTCGGCCATTTTGCCCGCCGTCATCTGAAAGGCGTGGGC
TTCAATGCTGTGACGCTGCTGGTCGCCGAAGAGATCCCCACCGGCAATGCGCTGATTTATGTCGCCGGTAACGATGCCGA
AAACATGATTGCCGTCGATCCCGGCGCGAATATGACGGTGACCGATGATGAAATCGCCGGCTGCATTCCCGCTATCGGCT
GCGCGGATGTGGTTCTGGTTCAGCTGGAGAACAATCTTTCTGCTATTGAACAGGTCATAGACGCCGGCAAACAAGCCGGG
GCCCTGGTAATACTCAATCCCGCGCCCTGGCAGCCCGTTGAGCACGCCGTTCTAAGCAAAGTGGATTTACTTACACCGAA
CGCCACGGAGGCCGGGTTAATGACCGGACGCAGGGTTGACAGTCTGACGGCCGCGGCTGAGGCCGCCGACGTGTTACATG
CTCAGGGCGCGCGCAACGTCATTATCACTCTCGGCGCCAGCGGCGCCCTGCTGAGCGAGCTGGGAGTGAAATCTCGTGTT
CCCTGCTTTCCTTCTCACCCCCGCGACACCACCGGTGCGGGCGATGCCTTCAACGGCGCGCTGGCGGCGCGGCTGGCCTG
CGGGGAACCGCTACAGGCCGCAGCCCGATTCGCGGCGGCCTATGCCGCCGTCAGTGTCGAAAAGCAAGGCGCCTCATCTT
TACCTGAGTACCTGGAGGCACAGGAACGGCTTCTCCGTGCCGCCGCTGATTATGAAATGGCATAA

Upstream 100 bases:

>100_bases
GTTTATTCCGCGCTGATATGCCGCTCGAGCTGGCCTGGGAAACCATGTCCCGCGAACTGTCCGCCGCGCTGCACTCCCCC
GAGCTGGTATAGAGGAGCGA

Downstream 100 bases:

>100_bases
ACCCTACTGTATAAAAAACATTAAGAGGATAGCTCAATGAGTACGCTAATCACGGATAAGGTCGATAACGCAGCGGTCCA
AAAAGAAAAACTGGACACCA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MMSGKVCVFGSFNFDMVARVDRFPVPGESLVACGSMTSAGGKGANQATAALKAGANVHYIGKIGNDTFGHFARRHLKGVG
FNAVTLLVAEEIPTGNALIYVAGNDAENMIAVDPGANMTVTDDEIAGCIPAIGCADVVLVQLENNLSAIEQVIDAGKQAG
ALVILNPAPWQPVEHAVLSKVDLLTPNATEAGLMTGRRVDSLTAAAEAADVLHAQGARNVIITLGASGALLSELGVKSRV
PCFPSHPRDTTGAGDAFNGALAARLACGEPLQAAARFAAAYAAVSVEKQGASSLPEYLEAQERLLRAAADYEMA

Sequences:

>Translated_314_residues
MMSGKVCVFGSFNFDMVARVDRFPVPGESLVACGSMTSAGGKGANQATAALKAGANVHYIGKIGNDTFGHFARRHLKGVG
FNAVTLLVAEEIPTGNALIYVAGNDAENMIAVDPGANMTVTDDEIAGCIPAIGCADVVLVQLENNLSAIEQVIDAGKQAG
ALVILNPAPWQPVEHAVLSKVDLLTPNATEAGLMTGRRVDSLTAAAEAADVLHAQGARNVIITLGASGALLSELGVKSRV
PCFPSHPRDTTGAGDAFNGALAARLACGEPLQAAARFAAAYAAVSVEKQGASSLPEYLEAQERLLRAAADYEMA
>Mature_314_residues
MMSGKVCVFGSFNFDMVARVDRFPVPGESLVACGSMTSAGGKGANQATAALKAGANVHYIGKIGNDTFGHFARRHLKGVG
FNAVTLLVAEEIPTGNALIYVAGNDAENMIAVDPGANMTVTDDEIAGCIPAIGCADVVLVQLENNLSAIEQVIDAGKQAG
ALVILNPAPWQPVEHAVLSKVDLLTPNATEAGLMTGRRVDSLTAAAEAADVLHAQGARNVIITLGASGALLSELGVKSRV
PCFPSHPRDTTGAGDAFNGALAARLACGEPLQAAARFAAAYAAVSVEKQGASSLPEYLEAQERLLRAAADYEMA

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=293, Percent_Identity=32.7645051194539, Blast_Score=117, Evalue=1e-26,
Organism=Escherichia coli, GI1790193, Length=294, Percent_Identity=39.7959183673469, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI87081971, Length=303, Percent_Identity=25.7425742574257, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87082343, Length=291, Percent_Identity=28.8659793814433, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788484, Length=286, Percent_Identity=25.8741258741259, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=292, Percent_Identity=35.6164383561644, Blast_Score=147, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6319884, Length=333, Percent_Identity=28.8288288288288, Blast_Score=102, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24583886, Length=293, Percent_Identity=32.0819112627986, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI20128807, Length=313, Percent_Identity=35.4632587859425, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32270; Mature: 32270

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSGKVCVFGSFNFDMVARVDRFPVPGESLVACGSMTSAGGKGANQATAALKAGANVHYI
CCCCCEEEEECCCHHHHHHHHCCCCCCHHHEEECCCCCCCCCCCCHHHHHHHCCCCEEEE
GKIGNDTFGHFARRHLKGVGFNAVTLLVAEEIPTGNALIYVAGNDAENMIAVDPGANMTV
EECCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCEEEECCCCCEEE
TDDEIAGCIPAIGCADVVLVQLENNLSAIEQVIDAGKQAGALVILNPAPWQPVEHAVLSK
CCHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHH
VDLLTPNATEAGLMTGRRVDSLTAAAEAADVLHAQGARNVIITLGASGALLSELGVKSRV
HHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHCCCCCCC
PCFPSHPRDTTGAGDAFNGALAARLACGEPLQAAARFAAAYAAVSVEKQGASSLPEYLEA
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCCHHHHHHHHHH
QERLLRAAADYEMA
HHHHHHHHHCCCCC
>Mature Secondary Structure
MMSGKVCVFGSFNFDMVARVDRFPVPGESLVACGSMTSAGGKGANQATAALKAGANVHYI
CCCCCEEEEECCCHHHHHHHHCCCCCCHHHEEECCCCCCCCCCCCHHHHHHHCCCCEEEE
GKIGNDTFGHFARRHLKGVGFNAVTLLVAEEIPTGNALIYVAGNDAENMIAVDPGANMTV
EECCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCEEEECCCCCEEE
TDDEIAGCIPAIGCADVVLVQLENNLSAIEQVIDAGKQAGALVILNPAPWQPVEHAVLSK
CCHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHH
VDLLTPNATEAGLMTGRRVDSLTAAAEAADVLHAQGARNVIITLGASGALLSELGVKSRV
HHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHCCCCCCC
PCFPSHPRDTTGAGDAFNGALAARLACGEPLQAAARFAAAYAAVSVEKQGASSLPEYLEA
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCCHHHHHHHHHH
QERLLRAAADYEMA
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]