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The map label for this gene is fucP [H]

Identifier: 238894743

GI number: 238894743

Start: 2626273

End: 2627607

Strand: Reverse

Name: fucP [H]

Synonym: KP1_2750

Alternate gene names: 238894743

Gene position: 2627607-2626273 (Counterclockwise)

Preceding gene: 238894744

Following gene: 238894742

Centisome position: 50.06

GC content: 55.51

Gene sequence:

>1335_bases
ATGAGTACGCTAATCACGGATAAGGTCGATAACGCAGCGGTCCAAAAAGAAAAACTGGACACCAGTGCGTATTTACCCCA
TACCCCCTGGCTGCAATTTTTACTGGTCTGTTGCCTGTTTGCGCTATGGGGGATGGCGGGCAACCTGAATGATATTTTGA
TCGCCCAGTTTAAAAAGGGCTTCGATTTAACGGATACCCAGACAGCGCTGGTGCAGTCGATTTTTTTCCTCGGCTACTTT
TTTGTCGCCCTGCCCGCGGCGGCGCTGATTAAGCGTTTCTCCTATAAAGCGGCGATTATTATTGGGCTGTGCCTGTACGC
CCTCGGCTGCTTCCTGTTCGTTCCGGCCGCACAGATCATGACCTACGGCGCGTTCCTCGCCTGCCTCGGAGTGATCGCCT
GCGGACTCTCTTTTCTGGAAACGTCGGCAAATACCTACTCCAGCCTGCTGGGTCCGATTCAATCCTCCACCCAGCGTATT
AACTTTTCGCAGATCTTCAACTCGCTGGGCGTGATCTCCGGCGTATTGATTGGCCAGCTGATGGTCTTTGGCGAAAACGA
TCCGAGTCATGAACAACTGCTGGCGATGCCCGCCTCCGCTGCAGACATTGCCCGCCATCAGATGGTCAGTCAGGTGGTCG
GGCCCTATCTGATTATCGGCTCCGTACTGGTGGTGCTGGCGCTGGTGTTCGTGTTTATTAAATTCCCGTCGTGCAAGGGC
GCGCCCGCTCAACAGCAACAACTCCCGACGGAAAGCATGGGGCCAACGCTGAAACGCCTGTTTGCTATCCCGCGCTTTCG
CCTCGGGATCCTGTCGCAGTTTTTGTACGTCGGCGCCCAGGTTGGCGTATGGAGCTTCACGATTCGCTTTGTGCAGCTCG
TGCAGCAAGGCACCAGCGAGCACTCCGCGACTTACTGGCTGCTGGCTTCTCTGGTGATTTACGCCGTGGGAAAAACCGTG
GCCACCTGGTTGATGAACCGTCTGAATCCGGCGATGCTGCTCGGAACGTTTGCCCTGGCCGCCACCGCCCTGTTACTGAT
TGCCGTTTTCAGCGGTTCAATGCTGGCGGTCTATGCGCTCATTCTGGTCAGCTTCTGTATGGCGCCATGCTGGCCGACGA
ACTTTGGTCTGGTGATCAAAGGGATGGGGAAAGATACCCAGACCGCAGGCTCGATCGTGGTGATGTCGATTATCGGCGGG
GCCGTAATTCCGCTGGTGATGGGCATTATCTCGGATATGAACGGCGGCAATATGCAAATCGCCTTTATCGCTCCGCTCCT
GTGCTTTGTGTATGTCGCTTTCTACGGCTTCTGGTGCGTGCGTAAGGGGGTATAA

Upstream 100 bases:

>100_bases
ACCTGAGTACCTGGAGGCACAGGAACGGCTTCTCCGTGCCGCCGCTGATTATGAAATGGCATAAACCCTACTGTATAAAA
AACATTAAGAGGATAGCTCA

Downstream 100 bases:

>100_bases
CATGCGCGAACTTATCAACACGATTGCTCATATTGGCTATCAGGTCAGTGACTTAACGCGTTCGCTTGCCTTCTATGAAC
CGCTGGGCTTTCAGCGCCAG

Product: fucose permease

Products: Proton [Cytoplasm]; L-fucose [Cytoplasm] [C]

Alternate protein names: 6-deoxy-L-galactose permease; L-fucose permease [H]

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MSTLITDKVDNAAVQKEKLDTSAYLPHTPWLQFLLVCCLFALWGMAGNLNDILIAQFKKGFDLTDTQTALVQSIFFLGYF
FVALPAAALIKRFSYKAAIIIGLCLYALGCFLFVPAAQIMTYGAFLACLGVIACGLSFLETSANTYSSLLGPIQSSTQRI
NFSQIFNSLGVISGVLIGQLMVFGENDPSHEQLLAMPASAADIARHQMVSQVVGPYLIIGSVLVVLALVFVFIKFPSCKG
APAQQQQLPTESMGPTLKRLFAIPRFRLGILSQFLYVGAQVGVWSFTIRFVQLVQQGTSEHSATYWLLASLVIYAVGKTV
ATWLMNRLNPAMLLGTFALAATALLLIAVFSGSMLAVYALILVSFCMAPCWPTNFGLVIKGMGKDTQTAGSIVVMSIIGG
AVIPLVMGIISDMNGGNMQIAFIAPLLCFVYVAFYGFWCVRKGV

Sequences:

>Translated_444_residues
MSTLITDKVDNAAVQKEKLDTSAYLPHTPWLQFLLVCCLFALWGMAGNLNDILIAQFKKGFDLTDTQTALVQSIFFLGYF
FVALPAAALIKRFSYKAAIIIGLCLYALGCFLFVPAAQIMTYGAFLACLGVIACGLSFLETSANTYSSLLGPIQSSTQRI
NFSQIFNSLGVISGVLIGQLMVFGENDPSHEQLLAMPASAADIARHQMVSQVVGPYLIIGSVLVVLALVFVFIKFPSCKG
APAQQQQLPTESMGPTLKRLFAIPRFRLGILSQFLYVGAQVGVWSFTIRFVQLVQQGTSEHSATYWLLASLVIYAVGKTV
ATWLMNRLNPAMLLGTFALAATALLLIAVFSGSMLAVYALILVSFCMAPCWPTNFGLVIKGMGKDTQTAGSIVVMSIIGG
AVIPLVMGIISDMNGGNMQIAFIAPLLCFVYVAFYGFWCVRKGV
>Mature_443_residues
STLITDKVDNAAVQKEKLDTSAYLPHTPWLQFLLVCCLFALWGMAGNLNDILIAQFKKGFDLTDTQTALVQSIFFLGYFF
VALPAAALIKRFSYKAAIIIGLCLYALGCFLFVPAAQIMTYGAFLACLGVIACGLSFLETSANTYSSLLGPIQSSTQRIN
FSQIFNSLGVISGVLIGQLMVFGENDPSHEQLLAMPASAADIARHQMVSQVVGPYLIIGSVLVVLALVFVFIKFPSCKGA
PAQQQQLPTESMGPTLKRLFAIPRFRLGILSQFLYVGAQVGVWSFTIRFVQLVQQGTSEHSATYWLLASLVIYAVGKTVA
TWLMNRLNPAMLLGTFALAATALLLIAVFSGSMLAVYALILVSFCMAPCWPTNFGLVIKGMGKDTQTAGSIVVMSIIGGA
VIPLVMGIISDMNGGNMQIAFIAPLLCFVYVAFYGFWCVRKGV

Specific function: Mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-

COG id: COG0738

COG function: function code G; Fucose permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family [H]

Homologues:

Organism=Escherichia coli, GI1789166, Length=422, Percent_Identity=40.521327014218, Blast_Score=294, Evalue=8e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005275
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47948; Mature: 47817

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STLITDKVDNAAVQKEKLDTSAYLPHTPWLQFLLVCCLFALWGMAGNLNDILIAQFKKG
CCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCC
FDLTDTQTALVQSIFFLGYFFVALPAAALIKRFSYKAAIIIGLCLYALGCFLFVPAAQIM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TYGAFLACLGVIACGLSFLETSANTYSSLLGPIQSSTQRINFSQIFNSLGVISGVLIGQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
MVFGENDPSHEQLLAMPASAADIARHQMVSQVVGPYLIIGSVLVVLALVFVFIKFPSCKG
HHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
APAQQQQLPTESMGPTLKRLFAIPRFRLGILSQFLYVGAQVGVWSFTIRFVQLVQQGTSE
CCCHHHCCCCHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HSATYWLLASLVIYAVGKTVATWLMNRLNPAMLLGTFALAATALLLIAVFSGSMLAVYAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ILVSFCMAPCWPTNFGLVIKGMGKDTQTAGSIVVMSIIGGAVIPLVMGIISDMNGGNMQI
HHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEH
AFIAPLLCFVYVAFYGFWCVRKGV
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-fucose [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-fucose [Periplasm] = Proton [Cytoplasm] + L-fucose [Cytoplasm] [C]

General reaction: Permease [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2664711; 9278503; 2553671; 8052131; 2829831; 7783647 [H]