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The map label for this gene is ybhO [H]

Identifier: 238893839

GI number: 238893839

Start: 1709954

End: 1711198

Strand: Reverse

Name: ybhO [H]

Synonym: KP1_1771

Alternate gene names: 238893839

Gene position: 1711198-1709954 (Counterclockwise)

Preceding gene: 238893840

Following gene: 238893838

Centisome position: 32.6

GC content: 60.32

Gene sequence:

>1245_bases
GTGAAATGTCGTTGGCAGGAAGGCAACCGCATTACGCTACTGGAGAATGGCGACCAGTACTATCCGGCGCTGTTTGCGGC
CATCGGTCGCGCCAGCCGGCGGGTGATCCTCGAATCCTTTATCTGGTTTGAAGATGAGGTTGGCCGGCGGCTGCACGCGG
TCCTGCTCGAGGCTGCCCGCCGTGGCATCCAGGTGGAGGTGCTCCTCGACGGCTATGGTTCCCCGGATCTCAGCGATGAA
TTTGTCGGTGAGCTCACCGCCGCTGGCGTGATTTTCCGCTACTACGATCCGCGTCCTAAGCTGATGGGGATGCGCACCAA
TCTGTTCCGTCGCATGCACCGTAAAATCGTGGTAATCGACGACACCACCGCCTTTGTCGGCGGTATTAACTACTCCGCCG
AACATATGAGCGACTACGGTCCGGAGGCGAAGCAGGATTATGCGGTGCAGGTCGAAGGGCCGGTGGTGCTCGACATCCTG
CAGTTCGAGCTGGAAAACCTGCCCAACAGCGAAACCGCCCGCCGCTGGTGGCGACGTCGTCGCCACCAGCCGGAGGTTAA
CCAGACCCCCGGCGAGGCGCAGGCGCTGTTCGTCTGGCGCGACAACCAGGATCACCGCGACGATATTGAACGCCACTACC
TGAAGATGCTGACCAGCGCCCGCCGGGAAGTGATTATCGCTAACGCCTATTTTTTCCCCGGCTACCGCCTGCTGCATGCG
ATGCGCAATGCCGCGCGGCGCGGAGTACGGGTTAAGCTGATCGTGCAGGGCGAACCGGATATTCCCATTGTGAAGTTTGG
CGCCCACCTGCTCTATCACTATCTCGTTAAGGGTGGGGTGCAGATTTACGAATATCGCCGTCGCCCGCTGCATGGCAAGG
TCGCTCTGGCAGACGACCACTGGGCCACCGTTGGGTCAAGCAACCTGGATCCGCTTAGCCTGTCGCTGAATCTGGAAGCC
AATCTGATCATCCACGATCGGGTGTTTAACCAGACGCTGCGCGATAATCTCAACGGGCTTATCGCCCGGGATTGCCAGCG
GATCGATAAAACGATGCTGCCGAAACGCAACTGGTGGCGGCTGGGCGTCAGCGTGATGGCTTTCCACTTTCTGCGCCACT
TCCCGGCATGGGTCGGCTGGCTACCGGCTCATACCCCGCGGCTGGCCAGAGTCAGCCCGCCGGTCCAGCCGGAAATTGAA
ACTCAGGACCGCGTCGAGTCTCCAGCCAGGGATAATCCACTATGA

Upstream 100 bases:

>100_bases
TTTACGTCAAGAACGCCCACGCCAGTCGCCCGAAGGCGCTGGCCCTTAAACAATGGCGGCATCTGTCCGATCATGCACCC
CTTAGCGTGGAGATACATTT

Downstream 100 bases:

>100_bases
GCAAATCACATCCCCGCTGGCGGATGGCGAAAAGAGTGCTGACCGTGCTCTTTTTTATCGCCGTCATCGTCCTGTTGGTG
ATCTACGCGCAAAAAGTCGA

Product: cardiolipin synthase 2

Products: NA

Alternate protein names: CL synthase [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MKCRWQEGNRITLLENGDQYYPALFAAIGRASRRVILESFIWFEDEVGRRLHAVLLEAARRGIQVEVLLDGYGSPDLSDE
FVGELTAAGVIFRYYDPRPKLMGMRTNLFRRMHRKIVVIDDTTAFVGGINYSAEHMSDYGPEAKQDYAVQVEGPVVLDIL
QFELENLPNSETARRWWRRRRHQPEVNQTPGEAQALFVWRDNQDHRDDIERHYLKMLTSARREVIIANAYFFPGYRLLHA
MRNAARRGVRVKLIVQGEPDIPIVKFGAHLLYHYLVKGGVQIYEYRRRPLHGKVALADDHWATVGSSNLDPLSLSLNLEA
NLIIHDRVFNQTLRDNLNGLIARDCQRIDKTMLPKRNWWRLGVSVMAFHFLRHFPAWVGWLPAHTPRLARVSPPVQPEIE
TQDRVESPARDNPL

Sequences:

>Translated_414_residues
MKCRWQEGNRITLLENGDQYYPALFAAIGRASRRVILESFIWFEDEVGRRLHAVLLEAARRGIQVEVLLDGYGSPDLSDE
FVGELTAAGVIFRYYDPRPKLMGMRTNLFRRMHRKIVVIDDTTAFVGGINYSAEHMSDYGPEAKQDYAVQVEGPVVLDIL
QFELENLPNSETARRWWRRRRHQPEVNQTPGEAQALFVWRDNQDHRDDIERHYLKMLTSARREVIIANAYFFPGYRLLHA
MRNAARRGVRVKLIVQGEPDIPIVKFGAHLLYHYLVKGGVQIYEYRRRPLHGKVALADDHWATVGSSNLDPLSLSLNLEA
NLIIHDRVFNQTLRDNLNGLIARDCQRIDKTMLPKRNWWRLGVSVMAFHFLRHFPAWVGWLPAHTPRLARVSPPVQPEIE
TQDRVESPARDNPL
>Mature_414_residues
MKCRWQEGNRITLLENGDQYYPALFAAIGRASRRVILESFIWFEDEVGRRLHAVLLEAARRGIQVEVLLDGYGSPDLSDE
FVGELTAAGVIFRYYDPRPKLMGMRTNLFRRMHRKIVVIDDTTAFVGGINYSAEHMSDYGPEAKQDYAVQVEGPVVLDIL
QFELENLPNSETARRWWRRRRHQPEVNQTPGEAQALFVWRDNQDHRDDIERHYLKMLTSARREVIIANAYFFPGYRLLHA
MRNAARRGVRVKLIVQGEPDIPIVKFGAHLLYHYLVKGGVQIYEYRRRPLHGKVALADDHWATVGSSNLDPLSLSLNLEA
NLIIHDRVFNQTLRDNLNGLIARDCQRIDKTMLPKRNWWRLGVSVMAFHFLRHFPAWVGWLPAHTPRLARVSPPVQPEIE
TQDRVESPARDNPL

Specific function: Catalyzes, in vitro, the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol [H]

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI1787007, Length=407, Percent_Identity=79.3611793611794, Blast_Score=682, Evalue=0.0,
Organism=Escherichia coli, GI1787502, Length=382, Percent_Identity=27.7486910994764, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87081826, Length=391, Percent_Identity=24.0409207161125, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: 2.7.8.-

Molecular weight: Translated: 47986; Mature: 47986

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCRWQEGNRITLLENGDQYYPALFAAIGRASRRVILESFIWFEDEVGRRLHAVLLEAAR
CCCEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGIQVEVLLDGYGSPDLSDEFVGELTAAGVIFRYYDPRPKLMGMRTNLFRRMHRKIVVID
CCCEEEEEEECCCCCCCCHHHHHHHHHHCEEEEEECCCCHHCCHHHHHHHHHCCEEEEEE
DTTAFVGGINYSAEHMSDYGPEAKQDYAVQVEGPVVLDILQFELENLPNSETARRWWRRR
CCCCEECCCCCCHHHHHHCCCCCCCCEEEEECCCEEEHHHHHHHHCCCCHHHHHHHHHHH
RHQPEVNQTPGEAQALFVWRDNQDHRDDIERHYLKMLTSARREVIIANAYFFPGYRLLHA
CCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHH
MRNAARRGVRVKLIVQGEPDIPIVKFGAHLLYHYLVKGGVQIYEYRRRPLHGKVALADDH
HHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHEEHHHCCCCCCEEEEECCC
WATVGSSNLDPLSLSLNLEANLIIHDRVFNQTLRDNLNGLIARDCQRIDKTMLPKRNWWR
EEECCCCCCCCEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LGVSVMAFHFLRHFPAWVGWLPAHTPRLARVSPPVQPEIETQDRVESPARDNPL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCC
>Mature Secondary Structure
MKCRWQEGNRITLLENGDQYYPALFAAIGRASRRVILESFIWFEDEVGRRLHAVLLEAAR
CCCEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGIQVEVLLDGYGSPDLSDEFVGELTAAGVIFRYYDPRPKLMGMRTNLFRRMHRKIVVID
CCCEEEEEEECCCCCCCCHHHHHHHHHHCEEEEEECCCCHHCCHHHHHHHHHCCEEEEEE
DTTAFVGGINYSAEHMSDYGPEAKQDYAVQVEGPVVLDILQFELENLPNSETARRWWRRR
CCCCEECCCCCCHHHHHHCCCCCCCCEEEEECCCEEEHHHHHHHHCCCCHHHHHHHHHHH
RHQPEVNQTPGEAQALFVWRDNQDHRDDIERHYLKMLTSARREVIIANAYFFPGYRLLHA
CCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHH
MRNAARRGVRVKLIVQGEPDIPIVKFGAHLLYHYLVKGGVQIYEYRRRPLHGKVALADDH
HHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHEEHHHCCCCCCEEEEECCC
WATVGSSNLDPLSLSLNLEANLIIHDRVFNQTLRDNLNGLIARDCQRIDKTMLPKRNWWR
EEECCCCCCCCEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LGVSVMAFHFLRHFPAWVGWLPAHTPRLARVSPPVQPEIETQDRVESPARDNPL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]