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The map label for this gene is dxs [C]

Identifier: 238893631

GI number: 238893631

Start: 1487350

End: 1488285

Strand: Direct

Name: dxs [C]

Synonym: KP1_1545

Alternate gene names: 238893631

Gene position: 1487350-1488285 (Clockwise)

Preceding gene: 238893630

Following gene: 238893634

Centisome position: 28.34

GC content: 62.39

Gene sequence:

>936_bases
ATGAGTAATGCAGAACACCTGGCTAACGTCATGGTCGAAGCCTTTATCGCCGCCGTGGAGCGCGGCGTCGATCTGGTGCC
GGTGGTAGCCGACTCCACGTCAACGGCCAAAATCGCGCCGTTTATTAAACAGTTCCCCGGCCGGCTGGTGAACGTCGGCA
TCGCCGAGCAGAGCATGGTCGGCACCGCCGCCGGTCTGGCGCTGGGCGGAAAAGTGGCGGTGACCTGTAACGCTGCGCCG
TTTCTTATCTCGCGGGCCAATGAGCAAATCAAAGTGGATGTCTGTTACAACAACACCAACGTCAAGCTGTTTGGCCTAAA
CGCCGGGGCCAGCTACGGTCCGCTGGCCAGCACCCACCATTCAATTGATGACCTGGCGGTGATGCGCGGCTTCGGCAATA
TCCAGATCTTCGCCCCCTCCACGCCGCGCGAATGTCGGCAGATCATAGACTATGCCCTTGCTTATCAGGGCCCGGTCTAT
ATTCGTCTCGATGGCAAGGCGCTGCCGGAGCTGCTTGACGAGTCGTATCGCTTTGTTCCTGGCGCTGTGCTGACCCTGCG
TGAAGGCGAGGACGTCGCGCTGGTGGCCACCGGTTCGACGGTGCATGAGGTGGTGGAGGCGGCGCAGCAGCTTGCCGACC
TCGGTATCCAGGCGAAAGTGGTCAGCGTGCCGTCGATTCGCCCCTGCGATACCGCGGCGCTGCTGGCGGCGCTCCAGCCA
TGTGGTTCGGTGATCACCGTCGAAGAGCATAACGTCAACGGCGGGTTGGGTAGCCTGGTGGCGGAAGTGCTGGCGGAAGC
GGGCGTGGGCATTGCCCTGCAGCGGTTGGGGATCCCGGACGGGGAGTACGCCGCCGCCGCCGATCGCGGCTGGATGCGTC
AGTACCATGGATTTGATGCCGCCGCCATCGTTGCCCTGGTGCAAAAAAGAGACTGA

Upstream 100 bases:

>100_bases
ACGAAAGGTGCCGGTATTTCCTTTATCCAGGGGCGCCCGGAGTGGCACCACCGGGTGCCGAAAGGCGAAGAAATTGCACT
GGCACTGGAGGAACTGAAAG

Downstream 100 bases:

>100_bases
TGGCCTGAACGCCCGTTGCGTGAAGCGCGGGCGTTTACTGCTGCAATGCGCAAAGTGTAATGACCTGCTCCTCCGACGCT
ATCCAGTGCAAGAGATAGCG

Product: putative transketolase C-terminal subunit

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSNAEHLANVMVEAFIAAVERGVDLVPVVADSTSTAKIAPFIKQFPGRLVNVGIAEQSMVGTAAGLALGGKVAVTCNAAP
FLISRANEQIKVDVCYNNTNVKLFGLNAGASYGPLASTHHSIDDLAVMRGFGNIQIFAPSTPRECRQIIDYALAYQGPVY
IRLDGKALPELLDESYRFVPGAVLTLREGEDVALVATGSTVHEVVEAAQQLADLGIQAKVVSVPSIRPCDTAALLAALQP
CGSVITVEEHNVNGGLGSLVAEVLAEAGVGIALQRLGIPDGEYAAAADRGWMRQYHGFDAAAIVALVQKRD

Sequences:

>Translated_311_residues
MSNAEHLANVMVEAFIAAVERGVDLVPVVADSTSTAKIAPFIKQFPGRLVNVGIAEQSMVGTAAGLALGGKVAVTCNAAP
FLISRANEQIKVDVCYNNTNVKLFGLNAGASYGPLASTHHSIDDLAVMRGFGNIQIFAPSTPRECRQIIDYALAYQGPVY
IRLDGKALPELLDESYRFVPGAVLTLREGEDVALVATGSTVHEVVEAAQQLADLGIQAKVVSVPSIRPCDTAALLAALQP
CGSVITVEEHNVNGGLGSLVAEVLAEAGVGIALQRLGIPDGEYAAAADRGWMRQYHGFDAAAIVALVQKRD
>Mature_310_residues
SNAEHLANVMVEAFIAAVERGVDLVPVVADSTSTAKIAPFIKQFPGRLVNVGIAEQSMVGTAAGLALGGKVAVTCNAAPF
LISRANEQIKVDVCYNNTNVKLFGLNAGASYGPLASTHHSIDDLAVMRGFGNIQIFAPSTPRECRQIIDYALAYQGPVYI
RLDGKALPELLDESYRFVPGAVLTLREGEDVALVATGSTVHEVVEAAQQLADLGIQAKVVSVPSIRPCDTAALLAALQPC
GSVITVEEHNVNGGLGSLVAEVLAEAGVGIALQRLGIPDGEYAAAADRGWMRQYHGFDAAAIVALVQKRD

Specific function: Catalyzes The Acyloin Condensation Reaction Between C Atoms 2 And 3 Of Pyruvate And Glyceraldehyde 3-Phosphate To Yield 1-Deoxy-D-Xylulose-5-Phosphate (Dxp). [C]

COG id: COG3958

COG function: function code G; Transketolase, C-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI133778974, Length=249, Percent_Identity=29.3172690763052, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI205277463, Length=235, Percent_Identity=28.5106382978723, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI4507521, Length=235, Percent_Identity=28.5106382978723, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI225637461, Length=224, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI225637463, Length=224, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI225637459, Length=224, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=9e-19,
Organism=Escherichia coli, GI1786622, Length=270, Percent_Identity=31.1111111111111, Blast_Score=104, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17539652, Length=240, Percent_Identity=29.1666666666667, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24645119, Length=223, Percent_Identity=28.2511210762332, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI45551847, Length=223, Percent_Identity=28.2511210762332, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI45550715, Length=223, Percent_Identity=28.2511210762332, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24666278, Length=225, Percent_Identity=26.2222222222222, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21358145, Length=237, Percent_Identity=25.7383966244726, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24650940, Length=237, Percent_Identity=25.7383966244726, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR020826
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 32603; Mature: 32471

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNAEHLANVMVEAFIAAVERGVDLVPVVADSTSTAKIAPFIKQFPGRLVNVGIAEQSMV
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCCHHHHH
GTAAGLALGGKVAVTCNAAPFLISRANEQIKVDVCYNNTNVKLFGLNAGASYGPLASTHH
HHHHHHEECCEEEEEECCCCEEEECCCCEEEEEEEECCCCEEEEEECCCCCCCCCCCCCC
SIDDLAVMRGFGNIQIFAPSTPRECRQIIDYALAYQGPVYIRLDGKALPELLDESYRFVP
CHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCCC
GAVLTLREGEDVALVATGSTVHEVVEAAQQLADLGIQAKVVSVPSIRPCDTAALLAALQP
CEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHC
CGSVITVEEHNVNGGLGSLVAEVLAEAGVGIALQRLGIPDGEYAAAADRGWMRQYHGFDA
CCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEHCCCCCCCCHHHHHHHHHHHHHCCCCH
AAIVALVQKRD
HHHHHHHHCCC
>Mature Secondary Structure 
SNAEHLANVMVEAFIAAVERGVDLVPVVADSTSTAKIAPFIKQFPGRLVNVGIAEQSMV
CCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCCHHHHH
GTAAGLALGGKVAVTCNAAPFLISRANEQIKVDVCYNNTNVKLFGLNAGASYGPLASTHH
HHHHHHEECCEEEEEECCCCEEEECCCCEEEEEEEECCCCEEEEEECCCCCCCCCCCCCC
SIDDLAVMRGFGNIQIFAPSTPRECRQIIDYALAYQGPVYIRLDGKALPELLDESYRFVP
CHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCCC
GAVLTLREGEDVALVATGSTVHEVVEAAQQLADLGIQAKVVSVPSIRPCDTAALLAALQP
CEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHC
CGSVITVEEHNVNGGLGSLVAEVLAEAGVGIALQRLGIPDGEYAAAADRGWMRQYHGFDA
CCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEHCCCCCCCCHHHHHHHHHHHHHCCCCH
AAIVALVQKRD
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]