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The map label for this gene is tktB [C]

Identifier: 238893630

GI number: 238893630

Start: 1486527

End: 1487357

Strand: Direct

Name: tktB [C]

Synonym: KP1_1544

Alternate gene names: 238893630

Gene position: 1486527-1487357 (Clockwise)

Preceding gene: 238893621

Following gene: 238893631

Centisome position: 28.32

GC content: 59.45

Gene sequence:

>831_bases
ATGAATCCCTACAGATATGATATTCAGACGCTGGAGCGTAAAGCCCGCGCGGTGCGGCGCCATATTGTGCGCTTAAACGC
CAATAGTCCGGCCGGCGGCCACACCGGGGCTGACCTTTCGCAGGTCGAACTGTTAACCGCGCTCTATTTCCGCGCCCTTA
ACGTCGCGCCGGACCGGCTCGACGACCCGCAGCGCGATATCTACATCCAGTCGAAAGGCCACGCCGTGGGCTGCTACTAC
TGCGTCCTGGCGGAAGCCGGCTTCTTCCCGGTCGAGTGGCTGGAGACCTACCAGCATGCCAATTCCCATCTCCCCGGCCA
CCCGGTGCGGCAAAAAACGCCGGGCATCGAGCTCAACACCGGCGCGCTGGGCCACGGTTTGCCTGTTGCGGTGGGGCTGG
CGCTGGCCGCGAAGAAAAGCAACAGCACCCGCCGCATTTTTTTGATCACCGGCGACGGCGAACTGGCGGAAGGCAGTAAC
TGGGAAGCCGCCCTGGCGGCTGCACATTACGGCCTGGATAATCTGGTCATTATTAATGATAAGAACAACCTCCAGCTGGC
CGGGCCGACGCGCGAAATCATGAATACCGATCCGCTGGCCGATAAATGGAAGGCCTTCGGGATGACGGTAACAGAATGCC
AGGGTAACGATATGTCCTCGGTGGTCGCGGCCATCGAGGGGTTGAAGCAGGAAGGTAAACCCAACGTTATTATTGCCAAC
ACCACGAAAGGTGCCGGTATTTCCTTTATCCAGGGGCGCCCGGAGTGGCACCACCGGGTGCCGAAAGGCGAAGAAATTGC
ACTGGCACTGGAGGAACTGAAAGATGAGTAA

Upstream 100 bases:

>100_bases
GCTGTGGCAGAAGGCTTACCACCCGGCATAGGGATATCTGGTTTTTTTAGTCCTTGCTGGAATAAATATTCCATGCTAAA
AATAAATTCAGAGGTGTGAA

Downstream 100 bases:

>100_bases
TGCAGAACACCTGGCTAACGTCATGGTCGAAGCCTTTATCGCCGCCGTGGAGCGCGGCGTCGATCTGGTGCCGGTGGTAG
CCGACTCCACGTCAACGGCC

Product: putative transketolase N-terminal subunit

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MNPYRYDIQTLERKARAVRRHIVRLNANSPAGGHTGADLSQVELLTALYFRALNVAPDRLDDPQRDIYIQSKGHAVGCYY
CVLAEAGFFPVEWLETYQHANSHLPGHPVRQKTPGIELNTGALGHGLPVAVGLALAAKKSNSTRRIFLITGDGELAEGSN
WEAALAAAHYGLDNLVIINDKNNLQLAGPTREIMNTDPLADKWKAFGMTVTECQGNDMSSVVAAIEGLKQEGKPNVIIAN
TTKGAGISFIQGRPEWHHRVPKGEEIALALEELKDE

Sequences:

>Translated_276_residues
MNPYRYDIQTLERKARAVRRHIVRLNANSPAGGHTGADLSQVELLTALYFRALNVAPDRLDDPQRDIYIQSKGHAVGCYY
CVLAEAGFFPVEWLETYQHANSHLPGHPVRQKTPGIELNTGALGHGLPVAVGLALAAKKSNSTRRIFLITGDGELAEGSN
WEAALAAAHYGLDNLVIINDKNNLQLAGPTREIMNTDPLADKWKAFGMTVTECQGNDMSSVVAAIEGLKQEGKPNVIIAN
TTKGAGISFIQGRPEWHHRVPKGEEIALALEELKDE
>Mature_276_residues
MNPYRYDIQTLERKARAVRRHIVRLNANSPAGGHTGADLSQVELLTALYFRALNVAPDRLDDPQRDIYIQSKGHAVGCYY
CVLAEAGFFPVEWLETYQHANSHLPGHPVRQKTPGIELNTGALGHGLPVAVGLALAAKKSNSTRRIFLITGDGELAEGSN
WEAALAAAHYGLDNLVIINDKNNLQLAGPTREIMNTDPLADKWKAFGMTVTECQGNDMSSVVAAIEGLKQEGKPNVIIAN
TTKGAGISFIQGRPEWHHRVPKGEEIALALEELKDE

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=264, Percent_Identity=34.469696969697, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI4507521, Length=264, Percent_Identity=34.469696969697, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI133778974, Length=258, Percent_Identity=33.3333333333333, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI225637459, Length=275, Percent_Identity=26.9090909090909, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI225637461, Length=162, Percent_Identity=34.5679012345679, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI225637463, Length=162, Percent_Identity=34.5679012345679, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1788808, Length=278, Percent_Identity=34.1726618705036, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI48994911, Length=255, Percent_Identity=29.4117647058824, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17539652, Length=256, Percent_Identity=34.375, Blast_Score=134, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6319593, Length=270, Percent_Identity=30, Blast_Score=105, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6325331, Length=228, Percent_Identity=32.4561403508772, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24666278, Length=269, Percent_Identity=33.457249070632, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI45551847, Length=274, Percent_Identity=33.5766423357664, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI45550715, Length=274, Percent_Identity=33.5766423357664, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24645119, Length=232, Percent_Identity=34.9137931034483, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 30135; Mature: 30135

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPYRYDIQTLERKARAVRRHIVRLNANSPAGGHTGADLSQVELLTALYFRALNVAPDRL
CCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
DDPQRDIYIQSKGHAVGCYYCVLAEAGFFPVEWLETYQHANSHLPGHPVRQKTPGIELNT
CCCCCEEEEEECCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEC
GALGHGLPVAVGLALAAKKSNSTRRIFLITGDGELAEGSNWEAALAAAHYGLDNLVIIND
CCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHCCCCEEEEEEC
KNNLQLAGPTREIMNTDPLADKWKAFGMTVTECQGNDMSSVVAAIEGLKQEGKPNVIIAN
CCCEEEECCHHHHCCCCCCHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEE
TTKGAGISFIQGRPEWHHRVPKGEEIALALEELKDE
CCCCCCEEEECCCCHHHHCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MNPYRYDIQTLERKARAVRRHIVRLNANSPAGGHTGADLSQVELLTALYFRALNVAPDRL
CCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
DDPQRDIYIQSKGHAVGCYYCVLAEAGFFPVEWLETYQHANSHLPGHPVRQKTPGIELNT
CCCCCEEEEEECCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEC
GALGHGLPVAVGLALAAKKSNSTRRIFLITGDGELAEGSNWEAALAAAHYGLDNLVIIND
CCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHCCCCEEEEEEC
KNNLQLAGPTREIMNTDPLADKWKAFGMTVTECQGNDMSSVVAAIEGLKQEGKPNVIIAN
CCCEEEECCHHHHCCCCCCHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEE
TTKGAGISFIQGRPEWHHRVPKGEEIALALEELKDE
CCCCCCEEEECCCCHHHHCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]