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The map label for this gene is fmt [H]

Identifier: 238028944

GI number: 238028944

Start: 3874583

End: 3875566

Strand: Reverse

Name: fmt [H]

Synonym: bglu_1g34090

Alternate gene names: 238028944

Gene position: 3875566-3874583 (Counterclockwise)

Preceding gene: 238028945

Following gene: 238028943

Centisome position: 99.21

GC content: 74.29

Gene sequence:

>984_bases
ATGACTCATTCGCTGCGCGTCATCTTCGCCGGTACGCCGGAATTCGCCGCGGCGGCGCTCGCCGCCATCCACGAGGCCGG
CTTCGCGGTGCCGCTGGTGCTGACCCAGCCCGACCGGCCGGCCGGGCGCGGCATGAAATTGCAGGCGAGCGCGGTCAAGC
GCTACGCACTCGATCACGGCATGCCGGTCGCGCAGCCGCCGTCGCTGCGTCGTACCGGCAAGTACCCGGCCGAGGCCGCC
GAGGCGCTCGACAGGTTGCGCGCGACGCCGCACGACGTGATGGTGGTGGCCGCCTACGGGCTGCTGCTGCCGCAGGAGGT
GCTCGAGATGCCGCCGCGCGGCTGTATCAATATCCACGCGTCGCTGCTGCCGCGCTGGCGCGGCGCGGCGCCGATCCATC
GAGCACTCGAGGCCGGCGACGCGCAGACGGGCGTCACGCTGATGCAGATGGACGTCGGGCTCGACACCGGCGCGATGCTG
TCCGAGGGGCGCGTCGCGATCGCGGCCGACGAGACCACCGCGTCGCTGCATGACAAGCTCGCGCAAACCGGCGCGCGGCT
GATCGTCGAGGCGCTCGTGCAGCTCGAACGCGACGGCGAGCTGGCCGCGACGCCGCAGCCTGCCGACGGCGTCACCTATG
CCGAGAAGATCGGCAAGCACGAGGCGGCGCTCGACTGGCGCGAGCCGGCCGCCGTGCTGGCGCGCCGGATCCGCGCGTTC
GACCCGTTCCCGGGCGGCGCCGGCACGCTCGACGGCACGGTGATCAAGCTGTGGGCGGCCGAGCCCGTCGTCGCGAGCGG
CGCGGCCGAGCCGGGCACGATCGTGGAGGCCGGCGCCGGCGGCGTCGTGATCGCGTGCGGCGAGGGCGCGCTGCGCGTCA
CGCAACTGCAGAAGCCGGGCGGCAAGCGCCTGCCCGCGCGAGAGTTTCTCGCCGGCGCGCCGCTCGCGGCCGGCCAGCGT
TTCGCGCTGCCCGAGGCCGGTTGA

Upstream 100 bases:

>100_bases
TGTTCGTGCAGTACCTGTCGCCGCTCAAGCAGAACCGCATCAAGTCCAAGATGAAGAAGCTCGAACGCGCGATGTGACGC
CCGTGATTGATCGATCCTCC

Downstream 100 bases:

>100_bases
AGACGGCCGCGCGGCCGGTGTAGCGCCGCGCCGGCGGCCGCCGCATCGCTCAAGAATCGGCGCACCGCATCGTAATCCGG
CCCCGATTCGCGCCGCGGTG

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTHSLRVIFAGTPEFAAAALAAIHEAGFAVPLVLTQPDRPAGRGMKLQASAVKRYALDHGMPVAQPPSLRRTGKYPAEAA
EALDRLRATPHDVMVVAAYGLLLPQEVLEMPPRGCINIHASLLPRWRGAAPIHRALEAGDAQTGVTLMQMDVGLDTGAML
SEGRVAIAADETTASLHDKLAQTGARLIVEALVQLERDGELAATPQPADGVTYAEKIGKHEAALDWREPAAVLARRIRAF
DPFPGGAGTLDGTVIKLWAAEPVVASGAAEPGTIVEAGAGGVVIACGEGALRVTQLQKPGGKRLPAREFLAGAPLAAGQR
FALPEAG

Sequences:

>Translated_327_residues
MTHSLRVIFAGTPEFAAAALAAIHEAGFAVPLVLTQPDRPAGRGMKLQASAVKRYALDHGMPVAQPPSLRRTGKYPAEAA
EALDRLRATPHDVMVVAAYGLLLPQEVLEMPPRGCINIHASLLPRWRGAAPIHRALEAGDAQTGVTLMQMDVGLDTGAML
SEGRVAIAADETTASLHDKLAQTGARLIVEALVQLERDGELAATPQPADGVTYAEKIGKHEAALDWREPAAVLARRIRAF
DPFPGGAGTLDGTVIKLWAAEPVVASGAAEPGTIVEAGAGGVVIACGEGALRVTQLQKPGGKRLPAREFLAGAPLAAGQR
FALPEAG
>Mature_326_residues
THSLRVIFAGTPEFAAAALAAIHEAGFAVPLVLTQPDRPAGRGMKLQASAVKRYALDHGMPVAQPPSLRRTGKYPAEAAE
ALDRLRATPHDVMVVAAYGLLLPQEVLEMPPRGCINIHASLLPRWRGAAPIHRALEAGDAQTGVTLMQMDVGLDTGAMLS
EGRVAIAADETTASLHDKLAQTGARLIVEALVQLERDGELAATPQPADGVTYAEKIGKHEAALDWREPAAVLARRIRAFD
PFPGGAGTLDGTVIKLWAAEPVVASGAAEPGTIVEAGAGGVVIACGEGALRVTQLQKPGGKRLPAREFLAGAPLAAGQRF
ALPEAG

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI238814322, Length=323, Percent_Identity=30.3405572755418, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI164663775, Length=326, Percent_Identity=29.4478527607362, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI21614513, Length=323, Percent_Identity=27.8637770897833, Blast_Score=102, Evalue=3e-22,
Organism=Escherichia coli, GI1789683, Length=310, Percent_Identity=51.2903225806452, Blast_Score=286, Evalue=1e-78,
Organism=Escherichia coli, GI1788589, Length=316, Percent_Identity=29.1139240506329, Blast_Score=135, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI133930964, Length=325, Percent_Identity=26.4615384615385, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6319458, Length=179, Percent_Identity=31.2849162011173, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45550868, Length=316, Percent_Identity=31.3291139240506, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28571984, Length=275, Percent_Identity=32.3636363636364, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24585660, Length=329, Percent_Identity=24.0121580547112, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 34035; Mature: 33903

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHSLRVIFAGTPEFAAAALAAIHEAGFAVPLVLTQPDRPAGRGMKLQASAVKRYALDHG
CCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEHHHHHHHHHHHCC
MPVAQPPSLRRTGKYPAEAAEALDRLRATPHDVMVVAAYGLLLPQEVLEMPPRGCINIHA
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHCCCCCCEEEEHH
SLLPRWRGAAPIHRALEAGDAQTGVTLMQMDVGLDTGAMLSEGRVAIAADETTASLHDKL
HHCCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEECCHHHHHHHHH
AQTGARLIVEALVQLERDGELAATPQPADGVTYAEKIGKHEAALDWREPAAVLARRIRAF
HHHHHHHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHCCHHHHCCCCCHHHHHHHHHHHC
DPFPGGAGTLDGTVIKLWAAEPVVASGAAEPGTIVEAGAGGVVIACGEGALRVTQLQKPG
CCCCCCCCCCCCEEEEEEECCCCEECCCCCCCCEEECCCCCEEEEECCCCEEEEEECCCC
GKRLPAREFLAGAPLAAGQRFALPEAG
CCCCCHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
THSLRVIFAGTPEFAAAALAAIHEAGFAVPLVLTQPDRPAGRGMKLQASAVKRYALDHG
CCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEHHHHHHHHHHHCC
MPVAQPPSLRRTGKYPAEAAEALDRLRATPHDVMVVAAYGLLLPQEVLEMPPRGCINIHA
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHCCCCCCEEEEHH
SLLPRWRGAAPIHRALEAGDAQTGVTLMQMDVGLDTGAMLSEGRVAIAADETTASLHDKL
HHCCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEECCHHHHHHHHH
AQTGARLIVEALVQLERDGELAATPQPADGVTYAEKIGKHEAALDWREPAAVLARRIRAF
HHHHHHHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHCCHHHHCCCCCHHHHHHHHHHHC
DPFPGGAGTLDGTVIKLWAAEPVVASGAAEPGTIVEAGAGGVVIACGEGALRVTQLQKPG
CCCCCCCCCCCCEEEEEEECCCCEECCCCCCCCEEECCCCCEEEEECCCCEEEEEECCCC
GKRLPAREFLAGAPLAAGQRFALPEAG
CCCCCHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA