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The map label for this gene is htpX [H]

Identifier: 238028942

GI number: 238028942

Start: 3872722

End: 3873579

Strand: Reverse

Name: htpX [H]

Synonym: bglu_1g34070

Alternate gene names: 238028942

Gene position: 3873579-3872722 (Counterclockwise)

Preceding gene: 238028943

Following gene: 339905983

Centisome position: 99.16

GC content: 68.41

Gene sequence:

>858_bases
ATGTTCAACTGGGTCAAGACGGCAATGCTGATGGCCGCGATCACGGCCCTCTTCATCGTGATCGGCGGGATGATCGGCGG
GTCGCGCGGCATGGCGATCGCGCTGCTGATCGCGCTGGGCATGAATTTCTTCTCGTACTGGTTCTCGGACAAGATGGTCC
TGCGCATGTACAACGCGCAGGAAGTGGACGAGGCCACGGCGCCGCAGTTCTACCGGATGGTGCGCGAGCTGGCCACGCGC
GCGAACCTGCCGATGCCGCGCGTCTACCTGATCGACGAGGCCGCGCCGAACGCCTTCGCGACCGGGCGTGATCCCGAGCA
CGCGGCGGTGGCGGCCACCACCGGCATCCTGCGCGTGCTGTCCGAGCGCGAGATGCGCGGCGTGATGGCCCACGAGCTTG
CGCACGTGAAGCACCGCGACATCCTGATCTCGACGATCTCGGCGACCATGGCCGGCGCGATCTCGGCGCTCGCCAACTTC
GCGATGTTCTTCGGCGGGCGCGACGAGAACGGCCGCCCGACCAACCCGATCGCCGGCATCGCGGTGGCGCTGCTCGCGCC
GATCGCCGGCGCGTTGATCCAGATGGCGATCTCGCGTGCGCGCGAGTTCGAGGCGGACCGCGGCGGCGCCCAGATCTCGG
GCGACCCGCAGGCGCTCGCGACGGCGCTCGACAAGATCCATCGCTATGCGTCGGGCATCCCGTTCCAGACGGCCGAGGCG
CATCCGGCCACGGCGCAGATGATGATCATGAACCCGCTGTCGGGTGGCAGCATCCAGAACCTGTTCTCGACCCACCCGGC
CACCGAGGAGCGCATCGCGCGCCTGATGGAAATGGCGCGCACCGGCCGCTTCGACTGA

Upstream 100 bases:

>100_bases
TTGAATTTTCCGCGCGCAGCCTTATCTAACGAATCGCTTACAATTTCTCGGCGGCGCGCCACGGATGCCGCCGCGTATGG
TTTCGATCAAGGAGTCGACT

Downstream 100 bases:

>100_bases
GTAGCCGGCGCCGGCAGCCTCGCGGCCCGGCGTCGTGCCGACGGCAGGCGGTATCCGGGCGGCCCGGCGGCGCATCGCGC
GTCGCCGGGCCGTCGGCATT

Product: M48 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MFNWVKTAMLMAAITALFIVIGGMIGGSRGMAIALLIALGMNFFSYWFSDKMVLRMYNAQEVDEATAPQFYRMVRELATR
ANLPMPRVYLIDEAAPNAFATGRDPEHAAVAATTGILRVLSEREMRGVMAHELAHVKHRDILISTISATMAGAISALANF
AMFFGGRDENGRPTNPIAGIAVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALATALDKIHRYASGIPFQTAEA
HPATAQMMIMNPLSGGSIQNLFSTHPATEERIARLMEMARTGRFD

Sequences:

>Translated_285_residues
MFNWVKTAMLMAAITALFIVIGGMIGGSRGMAIALLIALGMNFFSYWFSDKMVLRMYNAQEVDEATAPQFYRMVRELATR
ANLPMPRVYLIDEAAPNAFATGRDPEHAAVAATTGILRVLSEREMRGVMAHELAHVKHRDILISTISATMAGAISALANF
AMFFGGRDENGRPTNPIAGIAVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALATALDKIHRYASGIPFQTAEA
HPATAQMMIMNPLSGGSIQNLFSTHPATEERIARLMEMARTGRFD
>Mature_285_residues
MFNWVKTAMLMAAITALFIVIGGMIGGSRGMAIALLIALGMNFFSYWFSDKMVLRMYNAQEVDEATAPQFYRMVRELATR
ANLPMPRVYLIDEAAPNAFATGRDPEHAAVAATTGILRVLSEREMRGVMAHELAHVKHRDILISTISATMAGAISALANF
AMFFGGRDENGRPTNPIAGIAVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALATALDKIHRYASGIPFQTAEA
HPATAQMMIMNPLSGGSIQNLFSTHPATEERIARLMEMARTGRFD

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=272, Percent_Identity=30.5147058823529, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 30830; Mature: 30830

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.0 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNWVKTAMLMAAITALFIVIGGMIGGSRGMAIALLIALGMNFFSYWFSDKMVLRMYNAQ
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHH
EVDEATAPQFYRMVRELATRANLPMPRVYLIDEAAPNAFATGRDPEHAAVAATTGILRVL
HHHHHCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
SEREMRGVMAHELAHVKHRDILISTISATMAGAISALANFAMFFGGRDENGRPTNPIAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
AVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALATALDKIHRYASGIPFQTAEA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
HPATAQMMIMNPLSGGSIQNLFSTHPATEERIARLMEMARTGRFD
CCCHHEEEEECCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFNWVKTAMLMAAITALFIVIGGMIGGSRGMAIALLIALGMNFFSYWFSDKMVLRMYNAQ
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHH
EVDEATAPQFYRMVRELATRANLPMPRVYLIDEAAPNAFATGRDPEHAAVAATTGILRVL
HHHHHCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
SEREMRGVMAHELAHVKHRDILISTISATMAGAISALANFAMFFGGRDENGRPTNPIAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
AVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALATALDKIHRYASGIPFQTAEA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
HPATAQMMIMNPLSGGSIQNLFSTHPATEERIARLMEMARTGRFD
CCCHHEEEEECCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA