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The map label for this gene is paaF [C]

Identifier: 238028605

GI number: 238028605

Start: 3487753

End: 3488520

Strand: Reverse

Name: paaF [C]

Synonym: bglu_1g30690

Alternate gene names: 238028605

Gene position: 3488520-3487753 (Counterclockwise)

Preceding gene: 238028606

Following gene: 238028603

Centisome position: 89.3

GC content: 69.92

Gene sequence:

>768_bases
ATGGACATCCAGACCGACGTCGCGAACGGCGTCCTGACGATCACGATCGCGCGCCCTGCCAAGAAGAACGCGATCACCGC
GGCGATGTACCAGGCGATGGCCGATGCGCTCGCCGCCGCGCAGGAGGACAGCGCCGTGCGGGTGGTGCTGATCCGCGGCA
GCGACGGCAATTTCAGCGCGGGCAACGACCTCGAGGACTTCGTCAAGGTGCCGCCGAACACGCCGGATGCCCCCGTGTTC
CAGTTCCTGCACCAGATCAGCACGGCGGCCAAGCCGCTGGTTGCCGCGGTGTCGGGCATCGCGGTCGGCGTCGGCGTGAC
GATGCTGATGCACTGCGATCTCGTCTACGCGGCCGACACCGCCAAGCTGTCGCTGCCGTTCACGCAGCTCGGGCTGTGTC
CGGAAGCGGCCTCCAGCCTGCTGCTGCCGCGCCTGGCGGGCCACCAGGTGGCGGCCGAGAAGCTGATGCTCGGCGAGCCG
TTCGATGCGCTCGAAGCGCACCGCATCGGCCTCGTCAACCGCGTGCTGCCGGCCGCCGAACTTGAGGCGTTCGCCGCGCA
GCAGGCCGCCAAGCTCGCCGCGCTGCCGGCCTCGTCGCTGCGCGTGACGAAGGCGCTCATCAAGCAGACCGGCAGCGGCG
TGGCGGTGGCCGCGCGGATGGACGAGGAGGCGAGCCACTTCGGCAGGATGCTCGGCGCGCCCGAGGCGCGCGAGGCGATC
AGCGCGTTCTTCGAGAAGCGCAAGCCGGACTTTCGCCAGTTCGATTGA

Upstream 100 bases:

>100_bases
TCGAACGGCTGTAGGCGGGCAGCGTGCCCGATCATGGCGGTGCGCGGGCGGCTCGCTCGCGCACCGCTTTTTTATCGCTC
GGATTTGAGGAGACGGTGAG

Downstream 100 bases:

>100_bases
GCAAGCGGCGAGCGCGTCGAGCGCACTGAAAGCCGGCGATGCCGGCCGGCGCGATTGCTGCCGATGGCGTCGCGGATTGC
CGCCGGCAGCCGTGCGTCGC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MDIQTDVANGVLTITIARPAKKNAITAAMYQAMADALAAAQEDSAVRVVLIRGSDGNFSAGNDLEDFVKVPPNTPDAPVF
QFLHQISTAAKPLVAAVSGIAVGVGVTMLMHCDLVYAADTAKLSLPFTQLGLCPEAASSLLLPRLAGHQVAAEKLMLGEP
FDALEAHRIGLVNRVLPAAELEAFAAQQAAKLAALPASSLRVTKALIKQTGSGVAVAARMDEEASHFGRMLGAPEAREAI
SAFFEKRKPDFRQFD

Sequences:

>Translated_255_residues
MDIQTDVANGVLTITIARPAKKNAITAAMYQAMADALAAAQEDSAVRVVLIRGSDGNFSAGNDLEDFVKVPPNTPDAPVF
QFLHQISTAAKPLVAAVSGIAVGVGVTMLMHCDLVYAADTAKLSLPFTQLGLCPEAASSLLLPRLAGHQVAAEKLMLGEP
FDALEAHRIGLVNRVLPAAELEAFAAQQAAKLAALPASSLRVTKALIKQTGSGVAVAARMDEEASHFGRMLGAPEAREAI
SAFFEKRKPDFRQFD
>Mature_255_residues
MDIQTDVANGVLTITIARPAKKNAITAAMYQAMADALAAAQEDSAVRVVLIRGSDGNFSAGNDLEDFVKVPPNTPDAPVF
QFLHQISTAAKPLVAAVSGIAVGVGVTMLMHCDLVYAADTAKLSLPFTQLGLCPEAASSLLLPRLAGHQVAAEKLMLGEP
FDALEAHRIGLVNRVLPAAELEAFAAQQAAKLAALPASSLRVTKALIKQTGSGVAVAARMDEEASHFGRMLGAPEAREAI
SAFFEKRKPDFRQFD

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI45643119, Length=246, Percent_Identity=33.3333333333333, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI260275230, Length=246, Percent_Identity=33.3333333333333, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI260274832, Length=246, Percent_Identity=33.3333333333333, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI194097323, Length=249, Percent_Identity=28.5140562248996, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI31542718, Length=249, Percent_Identity=28.5140562248996, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI4757968, Length=258, Percent_Identity=26.3565891472868, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI49355787, Length=258, Percent_Identity=26.3565891472868, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI25453481, Length=258, Percent_Identity=25.968992248062, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI51538573, Length=258, Percent_Identity=25.968992248062, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4757966, Length=215, Percent_Identity=29.3023255813954, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI51538581, Length=215, Percent_Identity=29.3023255813954, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI68989263, Length=204, Percent_Identity=29.9019607843137, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4502327, Length=252, Percent_Identity=28.1746031746032, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI70995211, Length=186, Percent_Identity=30.1075268817204, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI221136756, Length=258, Percent_Identity=22.4806201550388, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI221136753, Length=258, Percent_Identity=22.4806201550388, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI221307494, Length=258, Percent_Identity=22.8682170542636, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI116235487, Length=199, Percent_Identity=27.6381909547739, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI37594469, Length=162, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI37594471, Length=162, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI62530384, Length=254, Percent_Identity=23.6220472440945, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI157694516, Length=246, Percent_Identity=23.1707317073171, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI213417737, Length=246, Percent_Identity=23.1707317073171, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787659, Length=243, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788597, Length=252, Percent_Identity=31.3492063492063, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1787660, Length=259, Percent_Identity=33.2046332046332, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI221142681, Length=253, Percent_Identity=33.201581027668, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082183, Length=248, Percent_Identity=27.0161290322581, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790281, Length=253, Percent_Identity=24.901185770751, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788682, Length=192, Percent_Identity=28.125, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17549921, Length=251, Percent_Identity=34.6613545816733, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17535521, Length=246, Percent_Identity=31.3008130081301, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI25145438, Length=251, Percent_Identity=28.2868525896414, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17554946, Length=252, Percent_Identity=30.952380952381, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17560910, Length=194, Percent_Identity=31.4432989690722, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17540306, Length=243, Percent_Identity=27.1604938271605, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17534483, Length=206, Percent_Identity=24.7572815533981, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17540714, Length=179, Percent_Identity=27.9329608938547, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17558304, Length=213, Percent_Identity=28.6384976525822, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=186, Percent_Identity=27.4193548387097, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24654903, Length=242, Percent_Identity=32.2314049586777, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24653139, Length=252, Percent_Identity=32.9365079365079, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI20129971, Length=256, Percent_Identity=29.296875, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24653477, Length=256, Percent_Identity=29.296875, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI19922422, Length=251, Percent_Identity=27.4900398406374, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21357171, Length=207, Percent_Identity=27.0531400966184, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI19920382, Length=183, Percent_Identity=25.6830601092896, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24650670, Length=196, Percent_Identity=29.0816326530612, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 26832; Mature: 26832

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIQTDVANGVLTITIARPAKKNAITAAMYQAMADALAAAQEDSAVRVVLIRGSDGNFSA
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCC
GNDLEDFVKVPPNTPDAPVFQFLHQISTAAKPLVAAVSGIAVGVGVTMLMHCDLVYAADT
CCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
AKLSLPFTQLGLCPEAASSLLLPRLAGHQVAAEKLMLGEPFDALEAHRIGLVNRVLPAAE
CEEECCHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHH
LEAFAAQQAAKLAALPASSLRVTKALIKQTGSGVAVAARMDEEASHFGRMLGAPEAREAI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCHHHHHH
SAFFEKRKPDFRQFD
HHHHHHCCCCCCCCC
>Mature Secondary Structure
MDIQTDVANGVLTITIARPAKKNAITAAMYQAMADALAAAQEDSAVRVVLIRGSDGNFSA
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCC
GNDLEDFVKVPPNTPDAPVFQFLHQISTAAKPLVAAVSGIAVGVGVTMLMHCDLVYAADT
CCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
AKLSLPFTQLGLCPEAASSLLLPRLAGHQVAAEKLMLGEPFDALEAHRIGLVNRVLPAAE
CEEECCHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHH
LEAFAAQQAAKLAALPASSLRVTKALIKQTGSGVAVAARMDEEASHFGRMLGAPEAREAI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCHHHHHH
SAFFEKRKPDFRQFD
HHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA