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The map label for this gene is sucC [H]

Identifier: 238028530

GI number: 238028530

Start: 3389918

End: 3391084

Strand: Reverse

Name: sucC [H]

Synonym: bglu_1g29940

Alternate gene names: 238028530

Gene position: 3391084-3389918 (Counterclockwise)

Preceding gene: 238028531

Following gene: 238028529

Centisome position: 86.81

GC content: 64.44

Gene sequence:

>1167_bases
ATGAAGATTCACGAGTACCAGGGTAAGGAAATCCTGCGGAAGTTCGGCGTCGCGGTCCCGCGCGGCAAGCCGGCGTTCTC
GGTGGACGAGGCGCTGAAGGTGGCGGAAGAGCTGGGCGGCCCGGTGTGGGTCGTCAAGGCGCAGATCCACGCGGGCGGCC
GCGGCAAGGGCGGTGGCGTGAAGGTGGCCAAATCGCTCGACCAGGTCCGTGAATACGCGAGCCAGATCCTCGGCATGCAG
CTGAAGACCCACCAGACCGGCCCGGAAGGCCAGAAGGTGAATCGCCTGCTGATCGAGGAAGGCGCCGACATCAAGAAGGA
ACTGTACGTCGGCATCGTGATCGATCGCGTCACGCAGAAGGTCGTCGTGATGGCCTCGAGCGAAGGCGGAATGGACATCG
AGGAAGTCGCGGAAAAGACGCCGGAGGCGCTGCACAAGGTCGCCGTCGAGCCGTCGAAGGGCCTGCAGGACGCGGAAGCC
GACGAGCTCGCCACCAAGATCGGCGTGCCGGCTGCCTCGCTGCCGCAAGCGCGCGCGATCCTGCAGAACCTGTACAAGGC
GTTCTGGGAAACCGACGCGTCGCTGGCCGAAATCAACCCGCTGGTGCTGACGGGCGACGGCAAGGTGATCGCGCTCGACG
CGAAGTTCAACTTCGATTCGAACGCGCTGTTCCGTCATCCGGAAATCGTCGCGTACCGCGATCTGGACGAAGAAGATCCG
GCTGAAATCGAAGCCTCGAAGTTCGACCTGGCCTACATCTCGCTCGACGGCAACATCGGCTGCCTGGTGAACGGTGCCGG
CCTGGCGATGGCGACCATGGACACGATCAAGCTGTTCGGCGGCGAGCCGGCCAACTTCCTCGACGTGGGCGGCGGCGCGA
CCACCGAGAAGGTGACCGAAGCGTTCAAGCTGATGCTGAAGAACCCGGACCTGAAGGCGATCCTGGTGAACATCTTCGGC
GGCATCATGCGCTGCGACGTGATCGCCGAGGGCGTGATCGCCGGCTCGAAGGCCGTCAATCTGGGCGTGCCGCTCGTGGT
GCGCATGAAGGGCACCAACGAGGACCTGGGCAAGAAGATGCTCGCCGAATCCGGCCTGCCGATCATCTCGGCGGACAGCA
TGGAAGAAGCGGCGCAGAAGGTCGTGGCGGCCGCTGCCGGCAAGTAA

Upstream 100 bases:

>100_bases
CTGCCGCGCGGGCGGCGCGCACGAATGATCGGAAACATCAGTAGAAAGAAGCGACATTCAATCGACTTTTCATCCAACTC
TCAGACTGAAGGAATCACGC

Downstream 100 bases:

>100_bases
GCATCGTTGCATTGAACACGCATGGCGGCGCGCCGGTTCGCGACGCCTATCGAACAGAGGTCAATACATGTCGATTCTGA
TCAACAAAGACACCAAGGTC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEALKVAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSLDQVREYASQILGMQ
LKTHQTGPEGQKVNRLLIEEGADIKKELYVGIVIDRVTQKVVVMASSEGGMDIEEVAEKTPEALHKVAVEPSKGLQDAEA
DELATKIGVPAASLPQARAILQNLYKAFWETDASLAEINPLVLTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPDLKAILVNIFG
GIMRCDVIAEGVIAGSKAVNLGVPLVVRMKGTNEDLGKKMLAESGLPIISADSMEEAAQKVVAAAAGK

Sequences:

>Translated_388_residues
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEALKVAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSLDQVREYASQILGMQ
LKTHQTGPEGQKVNRLLIEEGADIKKELYVGIVIDRVTQKVVVMASSEGGMDIEEVAEKTPEALHKVAVEPSKGLQDAEA
DELATKIGVPAASLPQARAILQNLYKAFWETDASLAEINPLVLTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPDLKAILVNIFG
GIMRCDVIAEGVIAGSKAVNLGVPLVVRMKGTNEDLGKKMLAESGLPIISADSMEEAAQKVVAAAAGK
>Mature_388_residues
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEALKVAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSLDQVREYASQILGMQ
LKTHQTGPEGQKVNRLLIEEGADIKKELYVGIVIDRVTQKVVVMASSEGGMDIEEVAEKTPEALHKVAVEPSKGLQDAEA
DELATKIGVPAASLPQARAILQNLYKAFWETDASLAEINPLVLTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPDLKAILVNIFG
GIMRCDVIAEGVIAGSKAVNLGVPLVVRMKGTNEDLGKKMLAESGLPIISADSMEEAAQKVVAAAAGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=389, Percent_Identity=47.5578406169666, Blast_Score=357, Evalue=1e-98,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=45.6919060052219, Blast_Score=328, Evalue=4e-90,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=45.6824512534819, Blast_Score=310, Evalue=2e-84,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=52.5773195876289, Blast_Score=399, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=45.29262086514, Blast_Score=344, Evalue=4e-95,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=45.1282051282051, Blast_Score=333, Evalue=6e-92,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=46.4285714285714, Blast_Score=357, Evalue=2e-99,
Organism=Drosophila melanogaster, GI21356231, Length=392, Percent_Identity=45.1530612244898, Blast_Score=331, Evalue=5e-91,
Organism=Drosophila melanogaster, GI161078106, Length=392, Percent_Identity=43.6224489795918, Blast_Score=317, Evalue=8e-87,
Organism=Drosophila melanogaster, GI24645208, Length=392, Percent_Identity=43.6224489795918, Blast_Score=317, Evalue=8e-87,
Organism=Drosophila melanogaster, GI281361397, Length=393, Percent_Identity=43.765903307888, Blast_Score=316, Evalue=2e-86,
Organism=Drosophila melanogaster, GI281361395, Length=393, Percent_Identity=43.765903307888, Blast_Score=316, Evalue=2e-86,
Organism=Drosophila melanogaster, GI281363475, Length=410, Percent_Identity=26.5853658536585, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI281363473, Length=410, Percent_Identity=26.5853658536585, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI281363477, Length=410, Percent_Identity=26.5853658536585, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41214; Mature: 41214

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50975 ATP_GRASP ; PS00063 ALDOKETO_REDUCTASE_3 ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEALKVAEELGGPVWVVKAQIHAGGRGKGGGV
CCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KVAKSLDQVREYASQILGMQLKTHQTGPEGQKVNRLLIEEGADIKKELYVGIVIDRVTQK
HHHHHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCE
VVVMASSEGGMDIEEVAEKTPEALHKVAVEPSKGLQDAEADELATKIGVPAASLPQARAI
EEEEECCCCCCCHHHHHHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
LQNLYKAFWETDASLAEINPLVLTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
HHHHHHHHHCCCCCHHHCCCEEEECCCEEEEEEEEECCCCCCEECCCCEEEECCCCCCCC
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTE
CCCCCCEEEEEEEEECCCEEEEEECCCEEHHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
AFKLMLKNPDLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLGVPLVVRMKGTNEDLGKKM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEECCCCHHHHHHH
LAESGLPIISADSMEEAAQKVVAAAAGK
HHHCCCCEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEALKVAEELGGPVWVVKAQIHAGGRGKGGGV
CCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KVAKSLDQVREYASQILGMQLKTHQTGPEGQKVNRLLIEEGADIKKELYVGIVIDRVTQK
HHHHHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCE
VVVMASSEGGMDIEEVAEKTPEALHKVAVEPSKGLQDAEADELATKIGVPAASLPQARAI
EEEEECCCCCCCHHHHHHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
LQNLYKAFWETDASLAEINPLVLTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
HHHHHHHHHCCCCCHHHCCCEEEECCCEEEEEEEEECCCCCCEECCCCEEEECCCCCCCC
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTE
CCCCCCEEEEEEEEECCCEEEEEECCCEEHHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
AFKLMLKNPDLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLGVPLVVRMKGTNEDLGKKM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEECCCCHHHHHHH
LAESGLPIISADSMEEAAQKVVAAAAGK
HHHCCCCEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA