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The map label for this gene is comA [H]

Identifier: 238028006

GI number: 238028006

Start: 2787003

End: 2789597

Strand: Reverse

Name: comA [H]

Synonym: bglu_1g24550

Alternate gene names: 238028006

Gene position: 2789597-2787003 (Counterclockwise)

Preceding gene: 238028007

Following gene: 238028005

Centisome position: 71.41

GC content: 75.84

Gene sequence:

>2595_bases
ATGCGGGAAGGCTGGATCGCGTTCGCGCTCGGCATCGTGCTGTTGCAGCGGCAGGCCGTGCTGCCGGATCCGTTGGGGTT
GGCGCTGGTGGCGACGGCCTGCGCGGTGCTGGCCGCTGCGGCGTGGCGCTGGCGGCGGGCCGCGGACCGCCGCGCGATGC
GATGGGCCGCGGGCGCGGCGATGCTGACGCTGGCGGTGCTGATCGGCTTCGCGTATGCCGCCGTGCGTGCGCACTGGCGG
CTCGCCGACTCGCTGCCGCTCGAATGGGAGCGGCGCGACATCGTCGTGACCGGCGTCGTGCATGGCCTGCCGGTGCGCGA
CGACGCGGGCCTGCGCTTCGTGCTCGAGGTCGACGGCAACGAGGCCGGGCTTGCGCGGTTTCCGGCCCGGCTGCGGCTGG
CGTGGATCACACGCGGCCGCCAGCCGGCCCCGCCCGTGATGCGCCCCGGCGAACGCTGGCGCCTGACGGTGCGGCTGAAG
CGCCCGCACGGCCATGCGAACCGGGGCGGGCGCGACGCGGAGGCGGGCTGGCTCGCGAACGGCATTCGCGCGCTCGGCTA
TGTGTCGTCGCCGCGCCTCGCGGCGCGCCTGGAACCGGGCGGGCAGGTGGGGCTGCATACCGGACTGCCCATGCCGCGCG
CGGCCATCGACCGGCTGCGCTTCGCGCTGCGCGAGCGGATTCGCGCGGTGCTCGGCGGTGCGCCGCACGCGGGGATCGTC
ATCGCGCTCGCGATCGGCGCGCAGGACGACATCTCGCAGGGCGATTGGCAGGTGCTGCGCGCCACCGGCACGAGCCATCT
GGTGGCGATCTCGGGCCTGCACATCAGCCTCGTCGGCGGGTTCGCGGGCGCGCTCGCGGCGGCGCTGTGGCGGCGCGCCT
CGCTGCGCGGCCGCGCGTTGCCGCTGTTTTTGCCGGCCCAGTACGCGGGCGCCTGCATGGCCGTCTGCGCGGCCGGCGCC
TATGCCGCGCTCGCCGGCTTCAACGTGCCGGCGCAGCGCGCTTGGTGGATGCTGACGGCCGCCTGCGTCGCCTATCTGAG
CGGGCGCACCGTCGCGCCCTCCACGACGCTCGCGTTCGCGCTCGGCTGCGTGCTGATCGCGGACCCGTGGGCCGTGCTCG
CGCCGGGCTTCTGGCTGTCGTTCTGCGCGGTGGCGGTGATCCTGTTCGCGGTGTCGGGGCGCCGGGTCCGGCGCTCAGTT
CGCGGCGATCCCGATTTCGCCGCGGCGGGCGAGCCGGAGCGGACGGCGACCGGCATGCCGGCATCGCCGCCGGCCGCGTC
GCCCGTCCGTTCGGCGTTGGCCGCCGTCATGCGGGCCGCCCGGCGCGTGCTGCGCGAGCGTCTGCGCCGTGCCGGCCCGC
GCTTCGTCGCGGGCGTGCGCACCCAGTACGCGGTGACGCTCGGGCTCGCGCCGCTGACGGTGGTCTGGTTCGGCCAGATT
CCGCTCGGCGGCGCGCCGGCCAACGCCGTCGCCATTCCCTGGGTGAGCTTGCTGGTCACGCCGCTCGTGCTGGCCGGCGT
GGCGTTGCCCGCGCCGCTCGACGCGCTGGCGCTGCGGGCCGCGCGGGCGCTGCTCGCCGTGCTGTTCGCGGGCTTCGACG
CAGCCGGCATGGATGGGCGCACGATGCTGTGGATGCCGTCGCCGCACTGGCCCGCGCTGGTGGCGGCCTGCATCGGCATG
GGCTGGGCGCTGATGCCGCGCGGCTGGCCGCTGCGCTGCGCGGCGCCGCTTGCCTGCCTGCCGTTCGTGCTGCCGCCGTC
GCAGGCGCCGCCGCCCGGCGCGTTCCGGCTGACCCTGCTCGACGTCGGGCAGGGCTTGTCCGCGGTGGTCGAGACGGCGC
ACCACGTTCTGGTGTTCGATGCCGGGCCCGGCGCCGAATCGACGCACGCCGGCGAGCGCGTGGTGGTGCCATATCTGCGC
TCGCGCGGCATCCACGCGCTCGATGCGCTGATGATCAGCCATCCCGACGCCGATCACGCGGGCGGCGCGGCCGCCGTGCT
CGAGGCGCTGCCGGTGCGCCAGCTGACGGGCAGCCTGCCGCGCGACGCCCCGTTGTGGCGGCGCGCGCGCGAAGGCGGCG
TGCGCGACCGTCTGGTCTGCGCGGCCGGGCAGCGCTGGCGCTGGGACGGCGTCACCTTCGCGGTGCTGTGGCCGCGCGAC
GGCCCGCGGGCCGCCGCGTCGAACGCGCGTTCGTGCGTGCTGCGCGTCTCGGCGGGCGGCCAGGCAGCACTCTTGACCGG
CGATATCGAACGCGGCGCCGAGCGGGCGCTGCTGGCCGCATCGCGCGCGCGTCTCGCGGCCGACGTGCTGGTGGTGCCGC
ACCATGGCAGCCGAACCTCGTCGTGGGAGCCGTTCGTCGACGCGATCGCGCCGCGCAGCGCGTGGTTCCCGCTCGGCTAC
GCGAACCGGTTCGGGCATCCGCATCCGACGGTCTGGGCGCGCTTCGTCGAGCGTGGCGTGCCGCTCGCACGCACTGATCG
CGACGGCGAGGTCAGCACGCTGCTCGGCAAGACCGGCACGCTCGCGCAAGCGGGCGGCGGGTTGCAGATCGAGCGCTATC
GAGCGGCCCATCGCCGTTACTGGATGGAACGCTGA

Upstream 100 bases:

>100_bases
TTCGGCCAGCGCGTGGGCCATGACGCCCCGGCGCGTTCGAGGGTCCGCATAATGACTCGCATGATGCGTCGCCTTCGCGG
CGCGCGGGACGGGAGGCGCG

Downstream 100 bases:

>100_bases
CGTGCCTTGCGGGCCGCGACGGCACCCGAGTAGAGGGAACCATCGAAGCGCCATCGGTGGCGGCGAACCGATATAAATCA
ATCGCTTATCGCGGTATGTC

Product: DNA internalization-related competence protein ComEC/Rec

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 864; Mature: 864

Protein sequence:

>864_residues
MREGWIAFALGIVLLQRQAVLPDPLGLALVATACAVLAAAAWRWRRAADRRAMRWAAGAAMLTLAVLIGFAYAAVRAHWR
LADSLPLEWERRDIVVTGVVHGLPVRDDAGLRFVLEVDGNEAGLARFPARLRLAWITRGRQPAPPVMRPGERWRLTVRLK
RPHGHANRGGRDAEAGWLANGIRALGYVSSPRLAARLEPGGQVGLHTGLPMPRAAIDRLRFALRERIRAVLGGAPHAGIV
IALAIGAQDDISQGDWQVLRATGTSHLVAISGLHISLVGGFAGALAAALWRRASLRGRALPLFLPAQYAGACMAVCAAGA
YAALAGFNVPAQRAWWMLTAACVAYLSGRTVAPSTTLAFALGCVLIADPWAVLAPGFWLSFCAVAVILFAVSGRRVRRSV
RGDPDFAAAGEPERTATGMPASPPAASPVRSALAAVMRAARRVLRERLRRAGPRFVAGVRTQYAVTLGLAPLTVVWFGQI
PLGGAPANAVAIPWVSLLVTPLVLAGVALPAPLDALALRAARALLAVLFAGFDAAGMDGRTMLWMPSPHWPALVAACIGM
GWALMPRGWPLRCAAPLACLPFVLPPSQAPPPGAFRLTLLDVGQGLSAVVETAHHVLVFDAGPGAESTHAGERVVVPYLR
SRGIHALDALMISHPDADHAGGAAAVLEALPVRQLTGSLPRDAPLWRRAREGGVRDRLVCAAGQRWRWDGVTFAVLWPRD
GPRAAASNARSCVLRVSAGGQAALLTGDIERGAERALLAASRARLAADVLVVPHHGSRTSSWEPFVDAIAPRSAWFPLGY
ANRFGHPHPTVWARFVERGVPLARTDRDGEVSTLLGKTGTLAQAGGGLQIERYRAAHRRYWMER

Sequences:

>Translated_864_residues
MREGWIAFALGIVLLQRQAVLPDPLGLALVATACAVLAAAAWRWRRAADRRAMRWAAGAAMLTLAVLIGFAYAAVRAHWR
LADSLPLEWERRDIVVTGVVHGLPVRDDAGLRFVLEVDGNEAGLARFPARLRLAWITRGRQPAPPVMRPGERWRLTVRLK
RPHGHANRGGRDAEAGWLANGIRALGYVSSPRLAARLEPGGQVGLHTGLPMPRAAIDRLRFALRERIRAVLGGAPHAGIV
IALAIGAQDDISQGDWQVLRATGTSHLVAISGLHISLVGGFAGALAAALWRRASLRGRALPLFLPAQYAGACMAVCAAGA
YAALAGFNVPAQRAWWMLTAACVAYLSGRTVAPSTTLAFALGCVLIADPWAVLAPGFWLSFCAVAVILFAVSGRRVRRSV
RGDPDFAAAGEPERTATGMPASPPAASPVRSALAAVMRAARRVLRERLRRAGPRFVAGVRTQYAVTLGLAPLTVVWFGQI
PLGGAPANAVAIPWVSLLVTPLVLAGVALPAPLDALALRAARALLAVLFAGFDAAGMDGRTMLWMPSPHWPALVAACIGM
GWALMPRGWPLRCAAPLACLPFVLPPSQAPPPGAFRLTLLDVGQGLSAVVETAHHVLVFDAGPGAESTHAGERVVVPYLR
SRGIHALDALMISHPDADHAGGAAAVLEALPVRQLTGSLPRDAPLWRRAREGGVRDRLVCAAGQRWRWDGVTFAVLWPRD
GPRAAASNARSCVLRVSAGGQAALLTGDIERGAERALLAASRARLAADVLVVPHHGSRTSSWEPFVDAIAPRSAWFPLGY
ANRFGHPHPTVWARFVERGVPLARTDRDGEVSTLLGKTGTLAQAGGGLQIERYRAAHRRYWMER
>Mature_864_residues
MREGWIAFALGIVLLQRQAVLPDPLGLALVATACAVLAAAAWRWRRAADRRAMRWAAGAAMLTLAVLIGFAYAAVRAHWR
LADSLPLEWERRDIVVTGVVHGLPVRDDAGLRFVLEVDGNEAGLARFPARLRLAWITRGRQPAPPVMRPGERWRLTVRLK
RPHGHANRGGRDAEAGWLANGIRALGYVSSPRLAARLEPGGQVGLHTGLPMPRAAIDRLRFALRERIRAVLGGAPHAGIV
IALAIGAQDDISQGDWQVLRATGTSHLVAISGLHISLVGGFAGALAAALWRRASLRGRALPLFLPAQYAGACMAVCAAGA
YAALAGFNVPAQRAWWMLTAACVAYLSGRTVAPSTTLAFALGCVLIADPWAVLAPGFWLSFCAVAVILFAVSGRRVRRSV
RGDPDFAAAGEPERTATGMPASPPAASPVRSALAAVMRAARRVLRERLRRAGPRFVAGVRTQYAVTLGLAPLTVVWFGQI
PLGGAPANAVAIPWVSLLVTPLVLAGVALPAPLDALALRAARALLAVLFAGFDAAGMDGRTMLWMPSPHWPALVAACIGM
GWALMPRGWPLRCAAPLACLPFVLPPSQAPPPGAFRLTLLDVGQGLSAVVETAHHVLVFDAGPGAESTHAGERVVVPYLR
SRGIHALDALMISHPDADHAGGAAAVLEALPVRQLTGSLPRDAPLWRRAREGGVRDRLVCAAGQRWRWDGVTFAVLWPRD
GPRAAASNARSCVLRVSAGGQAALLTGDIERGAERALLAASRARLAADVLVVPHHGSRTSSWEPFVDAIAPRSAWFPLGY
ANRFGHPHPTVWARFVERGVPLARTDRDGEVSTLLGKTGTLAQAGGGLQIERYRAAHRRYWMER

Specific function: Essential for natural transformation. Could be a transporter involved in DNA uptake [H]

COG id: COG0658

COG function: function code R; Predicted membrane metal-binding protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis ComEC, H.influenzae REC2, and E.coli YcaI [H]

Homologues:

Organism=Escherichia coli, GI87081801, Length=711, Percent_Identity=27.0042194092827, Blast_Score=190, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR004477
- InterPro:   IPR004797 [H]

Pfam domain/function: PF03772 Competence; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 91958; Mature: 91958

Theoretical pI: Translated: 11.87; Mature: 11.87

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREGWIAFALGIVLLQRQAVLPDPLGLALVATACAVLAAAAWRWRRAADRRAMRWAAGAA
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLTLAVLIGFAYAAVRAHWRLADSLPLEWERRDIVVTGVVHGLPVRDDAGLRFVLEVDGN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEECCC
EAGLARFPARLRLAWITRGRQPAPPVMRPGERWRLTVRLKRPHGHANRGGRDAEAGWLAN
CCCHHHCCHHEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHH
GIRALGYVSSPRLAARLEPGGQVGLHTGLPMPRAAIDRLRFALRERIRAVLGGAPHAGIV
HHHHHCCCCCCCEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEE
IALAIGAQDDISQGDWQVLRATGTSHLVAISGLHISLVGGFAGALAAALWRRASLRGRAL
EEEEECCCCCCCCCCEEEEEECCCCEEEEEECCEEEEHHHHHHHHHHHHHHHHCCCCCCE
PLFLPAQYAGACMAVCAAGAYAALAGFNVPAQRAWWMLTAACVAYLSGRTVAPSTTLAFA
EEEECHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LGCVLIADPWAVLAPGFWLSFCAVAVILFAVSGRRVRRSVRGDPDFAAAGEPERTATGMP
HHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCC
ASPPAASPVRSALAAVMRAARRVLRERLRRAGPRFVAGVRTQYAVTLGLAPLTVVWFGQI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHEEEEECCCCEEEEEECCC
PLGGAPANAVAIPWVSLLVTPLVLAGVALPAPLDALALRAARALLAVLFAGFDAAGMDGR
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TMLWMPSPHWPALVAACIGMGWALMPRGWPLRCAAPLACLPFVLPPSQAPPPGAFRLTLL
EEEEECCCCHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHCEECCCCCCCCCCCEEEEEE
DVGQGLSAVVETAHHVLVFDAGPGAESTHAGERVVVPYLRSRGIHALDALMISHPDADHA
ECCCCHHHHHHCCCEEEEEECCCCCCCCCCCCEEEEHHHHCCCCHHHHHHHHCCCCCCCC
GGAAAVLEALPVRQLTGSLPRDAPLWRRAREGGVRDRLVCAAGQRWRWDGVTFAVLWPRD
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHEEEECCCCCEEECCEEEEEEECCC
GPRAAASNARSCVLRVSAGGQAALLTGDIERGAERALLAASRARLAADVLVVPHHGSRTS
CCCHHHCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCC
SWEPFVDAIAPRSAWFPLGYANRFGHPHPTVWARFVERGVPLARTDRDGEVSTLLGKTGT
CCCHHHHHHCCCCCCCCCCHHHHCCCCCHHHHHHHHHCCCCEEECCCCCCHHHHHCCCCC
LAQAGGGLQIERYRAAHRRYWMER
HHCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MREGWIAFALGIVLLQRQAVLPDPLGLALVATACAVLAAAAWRWRRAADRRAMRWAAGAA
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLTLAVLIGFAYAAVRAHWRLADSLPLEWERRDIVVTGVVHGLPVRDDAGLRFVLEVDGN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEECCC
EAGLARFPARLRLAWITRGRQPAPPVMRPGERWRLTVRLKRPHGHANRGGRDAEAGWLAN
CCCHHHCCHHEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHH
GIRALGYVSSPRLAARLEPGGQVGLHTGLPMPRAAIDRLRFALRERIRAVLGGAPHAGIV
HHHHHCCCCCCCEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEE
IALAIGAQDDISQGDWQVLRATGTSHLVAISGLHISLVGGFAGALAAALWRRASLRGRAL
EEEEECCCCCCCCCCEEEEEECCCCEEEEEECCEEEEHHHHHHHHHHHHHHHHCCCCCCE
PLFLPAQYAGACMAVCAAGAYAALAGFNVPAQRAWWMLTAACVAYLSGRTVAPSTTLAFA
EEEECHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LGCVLIADPWAVLAPGFWLSFCAVAVILFAVSGRRVRRSVRGDPDFAAAGEPERTATGMP
HHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCC
ASPPAASPVRSALAAVMRAARRVLRERLRRAGPRFVAGVRTQYAVTLGLAPLTVVWFGQI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHEEEEECCCCEEEEEECCC
PLGGAPANAVAIPWVSLLVTPLVLAGVALPAPLDALALRAARALLAVLFAGFDAAGMDGR
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TMLWMPSPHWPALVAACIGMGWALMPRGWPLRCAAPLACLPFVLPPSQAPPPGAFRLTLL
EEEEECCCCHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHCEECCCCCCCCCCCEEEEEE
DVGQGLSAVVETAHHVLVFDAGPGAESTHAGERVVVPYLRSRGIHALDALMISHPDADHA
ECCCCHHHHHHCCCEEEEEECCCCCCCCCCCCEEEEHHHHCCCCHHHHHHHHCCCCCCCC
GGAAAVLEALPVRQLTGSLPRDAPLWRRAREGGVRDRLVCAAGQRWRWDGVTFAVLWPRD
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHEEEECCCCCEEECCEEEEEEECCC
GPRAAASNARSCVLRVSAGGQAALLTGDIERGAERALLAASRARLAADVLVVPHHGSRTS
CCCHHHCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCC
SWEPFVDAIAPRSAWFPLGYANRFGHPHPTVWARFVERGVPLARTDRDGEVSTLLGKTGT
CCCHHHHHHCCCCCCCCCCHHHHCCCCCHHHHHHHHHCCCCEEECCCCCCHHHHHCCCCC
LAQAGGGLQIERYRAAHRRYWMER
HHCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934834; 8830266 [H]