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The map label for this gene is fadD [C]

Identifier: 238027871

GI number: 238027871

Start: 2532118

End: 2533629

Strand: Reverse

Name: fadD [C]

Synonym: bglu_1g23040

Alternate gene names: 238027871

Gene position: 2533629-2532118 (Counterclockwise)

Preceding gene: 238027872

Following gene: 238027870

Centisome position: 64.86

GC content: 69.91

Gene sequence:

>1512_bases
ATGATGACCTTCGATGATCTCGTCGCGCGCCTGCGCGACAGCAGCCACACCCTGAGCTTCGTCGACGATCAGGGACGCGA
AACCGTCAGGACGTTCCACGAGCTGTTCGAAGACGTGTGCGCGACGGTGGCGCGCGGCCGCCGGCTCGGCCTCGTGCCGG
GCACGCGAGTGGGCCTCGCCGCGCCCAACGGCTATGCGTGGATGGTCTGGGACCTCGCGTGCCTGCAGCTCGGCTGCGTG
TCGGTGGCGCTGCCGAACGACGGATTGCACGACACCTGCGAGGCATTGATCGACCGCTATCGGCTGAGCGTCCTGGCCGT
CGATGCGGGATGGCTCGATCCCGCCGCGCCGCTGCCCGCGCGGGCCGTCGACATCGACCCGGCCGCCGCCGCGCGCGGCA
GCGACGTCGCGGTCGAGCCGGTGCGCGTCGAGGACGGCGCCGATACCCATTCGCTGGTGTTCAGCTCCGGCACGACCGGC
AAGAACAAGGGGCTCGTGATGAGCCGGCGCGGGACGGCGCATTTGCTTAACCTGTATGCCGACGCGTTCGGCGTGGCGCC
GGGCGAGCGATTCCTGACCTTCCTGCCGTTCGCGAACTATCAGCAGCGGATGACGTATTACTTCTGCCTGTATCACGGCA
TCGACCTGGTATCGGTGCCGTTTCACGGGCTGTTCCCGGGGCTCAAGCGGCACTGCCCGACCTTCGTGATCGGGCCGCCG
GTGCTCTACGAGACGCTGCACACGCTGGCCCGCGCGGCGGCCGGCCCGGCCGCCGACCGCACGGCGCTCGCGCAGCGGCT
CGCGGCGCTGACCGGCGGCAGGATTCGCTACATGATCACCGGGATGGCGCCGATCAAGCGCGCCGCGCTGGATTTCTTCT
GGGACTGCGGGATCGCGCTGTACGAGGCGTTCGGCATCACCGAGGCCGGGATGGTCGCGTGGAACAAGCCCGGATGCGTG
CGGGTCGGCACGGTCGGCAAGCCGGCGGAGCCGGGAACCGTGTCGCTGGCCGACGACGGCGAAGTGATCGTGACGCGCGA
CGCGCTGCTCTCGCTCGGCTATTTCGATGCGCCGATGGAGGACACGCGCGCCACCTACGTCGCACCGAACGCGGTCGCGA
CGGGCGACATCGGGGAGCTGGACGGCGACGGCTTTCTGCGCGTGGTCGGTCGCAAGAAGGACGCGATCGTCACCAGCAAC
GGCGAGAAGTTCCATCCGGAGCCGATCGAGTCGCTGCTGTATCGCGACCCGCGCGTCGAGGTGGCGGTGGTGATGGCCGG
CGCACGCGCCGGGCTCGCGGTGGTGATCGCGACGCGCCGGCCGGACGACCCCGAGGTGGCCGACGGGCTGCGCTCGCTCG
TGCGTTCGGTCAACGACACGCTGCCGGCGCAGCGCCAGCTCACGCAGATCATCTTCACCGACCGCGCCTTCGACGTCGAG
GGCGGGTTACGCACCCGCAATCTGAAGCTCAACCGCCGTGCGATCGCGGCCACGTTCCTGCGCGACGCGTGA

Upstream 100 bases:

>100_bases
CGCCATACCTGCAAGCTGTTCTGGAACATGTATGAAAGCGCCGCGCAGAAGTACTACGCCTCCGCGGAGGGCGTCGCGCT
CGCGTGACGGGGAAGCGCCG

Downstream 100 bases:

>100_bases
GATCGCGCCCGTGCGCGAGCCGCCTGCGCGCAGCGGCTCGCACCGACCTCATTCTGGACACACCATGACGACGCATTCGA
ACCCGAACGTGTTTCAGATG

Product: Long-chain-fatty-acid--CoA ligase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase; LACS [H]

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MMTFDDLVARLRDSSHTLSFVDDQGRETVRTFHELFEDVCATVARGRRLGLVPGTRVGLAAPNGYAWMVWDLACLQLGCV
SVALPNDGLHDTCEALIDRYRLSVLAVDAGWLDPAAPLPARAVDIDPAAAARGSDVAVEPVRVEDGADTHSLVFSSGTTG
KNKGLVMSRRGTAHLLNLYADAFGVAPGERFLTFLPFANYQQRMTYYFCLYHGIDLVSVPFHGLFPGLKRHCPTFVIGPP
VLYETLHTLARAAAGPAADRTALAQRLAALTGGRIRYMITGMAPIKRAALDFFWDCGIALYEAFGITEAGMVAWNKPGCV
RVGTVGKPAEPGTVSLADDGEVIVTRDALLSLGYFDAPMEDTRATYVAPNAVATGDIGELDGDGFLRVVGRKKDAIVTSN
GEKFHPEPIESLLYRDPRVEVAVVMAGARAGLAVVIATRRPDDPEVADGLRSLVRSVNDTLPAQRQLTQIIFTDRAFDVE
GGLRTRNLKLNRRAIAATFLRDA

Sequences:

>Translated_503_residues
MMTFDDLVARLRDSSHTLSFVDDQGRETVRTFHELFEDVCATVARGRRLGLVPGTRVGLAAPNGYAWMVWDLACLQLGCV
SVALPNDGLHDTCEALIDRYRLSVLAVDAGWLDPAAPLPARAVDIDPAAAARGSDVAVEPVRVEDGADTHSLVFSSGTTG
KNKGLVMSRRGTAHLLNLYADAFGVAPGERFLTFLPFANYQQRMTYYFCLYHGIDLVSVPFHGLFPGLKRHCPTFVIGPP
VLYETLHTLARAAAGPAADRTALAQRLAALTGGRIRYMITGMAPIKRAALDFFWDCGIALYEAFGITEAGMVAWNKPGCV
RVGTVGKPAEPGTVSLADDGEVIVTRDALLSLGYFDAPMEDTRATYVAPNAVATGDIGELDGDGFLRVVGRKKDAIVTSN
GEKFHPEPIESLLYRDPRVEVAVVMAGARAGLAVVIATRRPDDPEVADGLRSLVRSVNDTLPAQRQLTQIIFTDRAFDVE
GGLRTRNLKLNRRAIAATFLRDA
>Mature_503_residues
MMTFDDLVARLRDSSHTLSFVDDQGRETVRTFHELFEDVCATVARGRRLGLVPGTRVGLAAPNGYAWMVWDLACLQLGCV
SVALPNDGLHDTCEALIDRYRLSVLAVDAGWLDPAAPLPARAVDIDPAAAARGSDVAVEPVRVEDGADTHSLVFSSGTTG
KNKGLVMSRRGTAHLLNLYADAFGVAPGERFLTFLPFANYQQRMTYYFCLYHGIDLVSVPFHGLFPGLKRHCPTFVIGPP
VLYETLHTLARAAAGPAADRTALAQRLAALTGGRIRYMITGMAPIKRAALDFFWDCGIALYEAFGITEAGMVAWNKPGCV
RVGTVGKPAEPGTVSLADDGEVIVTRDALLSLGYFDAPMEDTRATYVAPNAVATGDIGELDGDGFLRVVGRKKDAIVTSN
GEKFHPEPIESLLYRDPRVEVAVVMAGARAGLAVVIATRRPDDPEVADGLRSLVRSVNDTLPAQRQLTQIIFTDRAFDVE
GGLRTRNLKLNRRAIAATFLRDA

Specific function: Esterification, Concomitant With Transport, Of Exogenous Long-Chain Fatty Acids Into Metabolically Active CoA Thioesters For Subsequent Degradation Or Incorporation Into Phospholipids. [C]

COG id: COG1022

COG function: function code I; Long-chain acyl-CoA synthetases (AMP-forming)

Gene ontology:

Cell location: Partially Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI42794760, Length=546, Percent_Identity=23.4432234432234, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI42794758, Length=546, Percent_Identity=23.4432234432234, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI42794756, Length=546, Percent_Identity=23.4432234432234, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI27477105, Length=359, Percent_Identity=24.7910863509749, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI57165410, Length=545, Percent_Identity=23.1192660550459, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI57165412, Length=545, Percent_Identity=23.1192660550459, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI122937307, Length=189, Percent_Identity=31.7460317460317, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17556552, Length=563, Percent_Identity=22.9129662522202, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17558820, Length=326, Percent_Identity=26.9938650306748, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI32563687, Length=394, Percent_Identity=24.6192893401015, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25147511, Length=566, Percent_Identity=22.4381625441696, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17541856, Length=572, Percent_Identity=23.0769230769231, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324893, Length=335, Percent_Identity=25.6716417910448, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19921316, Length=361, Percent_Identity=23.8227146814404, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 54371; Mature: 54371

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTFDDLVARLRDSSHTLSFVDDQGRETVRTFHELFEDVCATVARGRRLGLVPGTRVGLA
CCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEE
APNGYAWMVWDLACLQLGCVSVALPNDGLHDTCEALIDRYRLSVLAVDAGWLDPAAPLPA
CCCCCEEHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCC
RAVDIDPAAAARGSDVAVEPVRVEDGADTHSLVFSSGTTGKNKGLVMSRRGTAHLLNLYA
CEEECCCHHCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCEEEECCCHHHHHHHHH
DAFGVAPGERFLTFLPFANYQQRMTYYFCLYHGIDLVSVPFHGLFPGLKRHCPTFVIGPP
HHHCCCCCHHHEEECCCCCHHHHHHHEEHHHHCCCEEECCCHHHCCHHHHHCCEEEECCH
VLYETLHTLARAAAGPAADRTALAQRLAALTGGRIRYMITGMAPIKRAALDFFWDCGIAL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
YEAFGITEAGMVAWNKPGCVRVGTVGKPAEPGTVSLADDGEVIVTRDALLSLGYFDAPME
HHHHCCCCCCEEEECCCCEEEECCCCCCCCCCEEEECCCCCEEEEHHHHHHCCCCCCCCC
DTRATYVAPNAVATGDIGELDGDGFLRVVGRKKDAIVTSNGEKFHPEPIESLLYRDPRVE
CCCEEEECCCCEECCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCHHHHHHCCCCCCE
VAVVMAGARAGLAVVIATRRPDDPEVADGLRSLVRSVNDTLPAQRQLTQIIFTDRAFDVE
EEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHEECCEEECC
GGLRTRNLKLNRRAIAATFLRDA
CCCEECCEEECHHHHHHHHHHCC
>Mature Secondary Structure
MMTFDDLVARLRDSSHTLSFVDDQGRETVRTFHELFEDVCATVARGRRLGLVPGTRVGLA
CCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEE
APNGYAWMVWDLACLQLGCVSVALPNDGLHDTCEALIDRYRLSVLAVDAGWLDPAAPLPA
CCCCCEEHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCC
RAVDIDPAAAARGSDVAVEPVRVEDGADTHSLVFSSGTTGKNKGLVMSRRGTAHLLNLYA
CEEECCCHHCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCEEEECCCHHHHHHHHH
DAFGVAPGERFLTFLPFANYQQRMTYYFCLYHGIDLVSVPFHGLFPGLKRHCPTFVIGPP
HHHCCCCCHHHEEECCCCCHHHHHHHEEHHHHCCCEEECCCHHHCCHHHHHCCEEEECCH
VLYETLHTLARAAAGPAADRTALAQRLAALTGGRIRYMITGMAPIKRAALDFFWDCGIAL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
YEAFGITEAGMVAWNKPGCVRVGTVGKPAEPGTVSLADDGEVIVTRDALLSLGYFDAPME
HHHHCCCCCCEEEECCCCEEEECCCCCCCCCCEEEECCCCCEEEEHHHHHHCCCCCCCCC
DTRATYVAPNAVATGDIGELDGDGFLRVVGRKKDAIVTSNGEKFHPEPIESLLYRDPRVE
CCCEEEECCCCEECCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCHHHHHHCCCCCCE
VAVVMAGARAGLAVVIATRRPDDPEVADGLRSLVRSVNDTLPAQRQLTQIIFTDRAFDVE
EEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHEECCEEECC
GGLRTRNLKLNRRAIAATFLRDA
CCCEECCEEECHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]