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The map label for this gene is yhcV [H]

Identifier: 238027425

GI number: 238027425

Start: 2000899

End: 2001327

Strand: Direct

Name: yhcV [H]

Synonym: bglu_1g18280

Alternate gene names: 238027425

Gene position: 2000899-2001327 (Clockwise)

Preceding gene: 238027420

Following gene: 238027429

Centisome position: 51.22

GC content: 71.33

Gene sequence:

>429_bases
ATGATTCGGGTAGCGGATGTGATGTCGCGCGACGTGGTATCGATCGCGCCGAACGACTCGGTACGGCACGCGGCGCAGTG
CATGGCGCACTACGACGTGGGCGCCTTGCCGGTGTGCGATCGCGGCCGCCTCGTCGGCATCGTGACCGACCGCGATCTGG
CGGTGCGCGTGCTGGCCGACGACGTCGGCCCCGACACGGCGATCGGCGAGGTCGCGACCCGGCGGCCGGTCTGCTGCCGC
GAGCACGACGATCTGGACGCGGTCCAGCAGCGCATGGCCGAGGCTCGCATCCGGCGCACGCCGGTGGTCACGGCGAGCGG
GCAACTGGTGGGCATGCTGTCGCTCGGCGACATCGCCACGCGCGCCCAGGGCGCGTCTCAGGACGAACTGGCGAACACGC
TCGAACGCGTCTCGCAGCCGGGGCAATGA

Upstream 100 bases:

>100_bases
GGGCGCACGCTTGCGTCGCCCAGGAACCGCGCAAGCGCCATGCCGCGTGCCGGCACGCGAATTGCGCGCTGCCCGGGCAG
GCAACGACGGAGGACAAGCA

Downstream 100 bases:

>100_bases
CGGGCGGCCCGGCCGGCGTGGCGCGGCATCAGTAGGTCGGCAGGCCGATGCAGGCGTTCGGGTCGACCGAGGCGCAGGCG
ATCGAATAGCCGGCCGCGCT

Product: CBS domain-containing protein

Products: H+; Nicotinamide adenine dinucleotide - reduced; Xanthosine 5'-phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MIRVADVMSRDVVSIAPNDSVRHAAQCMAHYDVGALPVCDRGRLVGIVTDRDLAVRVLADDVGPDTAIGEVATRRPVCCR
EHDDLDAVQQRMAEARIRRTPVVTASGQLVGMLSLGDIATRAQGASQDELANTLERVSQPGQ

Sequences:

>Translated_142_residues
MIRVADVMSRDVVSIAPNDSVRHAAQCMAHYDVGALPVCDRGRLVGIVTDRDLAVRVLADDVGPDTAIGEVATRRPVCCR
EHDDLDAVQQRMAEARIRRTPVVTASGQLVGMLSLGDIATRAQGASQDELANTLERVSQPGQ
>Mature_142_residues
MIRVADVMSRDVVSIAPNDSVRHAAQCMAHYDVGALPVCDRGRLVGIVTDRDLAVRVLADDVGPDTAIGEVATRRPVCCR
EHDDLDAVQQRMAEARIRRTPVVTASGQLVGMLSLGDIATRAQGASQDELANTLERVSQPGQ

Specific function: GMP biosynthesis from IMP; first step. [C]

COG id: COG0517

COG function: function code R; FOG: CBS domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

None

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644 [H]

Pfam domain/function: PF00571 CBS [H]

EC number: 1.1.1.205 [C]

Molecular weight: Translated: 15230; Mature: 15230

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVADVMSRDVVSIAPNDSVRHAAQCMAHYDVGALPVCDRGRLVGIVTDRDLAVRVLAD
CEEHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEEEC
DVGPDTAIGEVATRRPVCCREHDDLDAVQQRMAEARIRRTPVVTASGQLVGMLSLGDIAT
CCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCEEEEEECCHHHH
RAQGASQDELANTLERVSQPGQ
HCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIRVADVMSRDVVSIAPNDSVRHAAQCMAHYDVGALPVCDRGRLVGIVTDRDLAVRVLAD
CEEHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEEEC
DVGPDTAIGEVATRRPVCCREHDDLDAVQQRMAEARIRRTPVVTASGQLVGMLSLGDIAT
CCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCEEEEEECCHHHH
RAQGASQDELANTLERVSQPGQ
HCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; IMP; Nicotinamide adenine dinucleotide [C]

Specific reaction: H2O + IMP + Nicotinamide adenine dinucleotide --> H+ + Nicotinamide adenine dinucleotide - reduced + Xanthosine 5'-phosphate [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]