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The map label for this gene is yeaP [H]

Identifier: 238027429

GI number: 238027429

Start: 2004542

End: 2005516

Strand: Direct

Name: yeaP [H]

Synonym: bglu_1g18320

Alternate gene names: 238027429

Gene position: 2004542-2005516 (Clockwise)

Preceding gene: 238027425

Following gene: 238027431

Centisome position: 51.31

GC content: 69.33

Gene sequence:

>975_bases
ATGCAAATCGCTCCCTTACCCGTCAACGAAGCTTCACGGCTTGCCCGGCTGCATGGTCTGGATCTGCTCGACACGCCCGA
CGAGGAACGCTTCGACCGCATCGCCCGGCTCGCCCGGCGTATCTTCGACGTGCCGATCGCGCTCGTCTCGCTGATCGACG
CGAACCGCCAGTGGTTCAAGAGCTGCTTTGGCCTGGAGGCGCGCGAGACCTCGCGCGACGTCTCGTTCTGCGCCCACGCG
ATCCTCTCCGACGACACGCTCGTGATCCCCGACGCCACGCTCGACCCGCGCTTCGCCGGCAACCCGCTCGTCACCGGGGC
GCCGGGCATCCGCTTCTACGCCGGGCATCCGCTCGCGCTGCCCGACGGCACCAATCTGGGCACGCTGTGCCTGATCGATA
CGCGCCCGCGCGAGATCGACGCGACCGACCTGAGCCACCTGCGGGATCTGGCGAACCTGGCCGAGCGCGAGGTGGCGGCC
GTGCAGCTGGCCACGCTCGATTCGCTGACCGCGCTGTCGAACCGGCGCGGCTTCGAGATGCTCTCGCAGCAGGCGCTGAA
CGCGTGCCGGCGGCGCGGCCTGCCGGCCTCGCTGCTGTTCTTCGATCTGGACGGCTTCAAGCAGATCAACGACCGTTTCG
GCCACGCCGAGGGCGACCGCGCGCTGGTGCTGTTCGCGCGTTCGCTCACCACCGTGCTGCGCGAGATGGACGTGATCGGG
CGGCTCGGCGGCGACGAGTTCGTCGCGCTGGTGATGTCCGAACAGCTCGACGTGCAGGCGCTGGTGGAGCGGCTGCGCAA
GGATCTCGGCGCGCGCGGCAGGCAGGCCGGGCTCGAATACGAGATCCGCTTCAGTGTCGGCCACGTCGATTACGACCCGC
GCGACGAGCCCTCGGTCGCCCGGCTGCTCGCCGAATCGGACCTGCGCATGTACGCCGACAAGAGCCGCATGAAATCGCGG
GCCGCGCCGCACTGA

Upstream 100 bases:

>100_bases
TGCTCTACGATGACACCATCGATCTGCCGCCCGCGCGCCCCGGCCAGGACAGCCCTGGGCGCAGGCGGCCAGGCCATCCG
ACTTCGTGAGATCCGATCGC

Downstream 100 bases:

>100_bases
GCCTGCGATCGGGAGTCGCCCGCCGGACCTTGCTGCGGCTTCGGCATTTCGCCGCCCGGCCGCGCCGGGAGCGCCGGTGG
CGGCATACCCGGTGCCGCCG

Product: diguanylate cyclase

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MQIAPLPVNEASRLARLHGLDLLDTPDEERFDRIARLARRIFDVPIALVSLIDANRQWFKSCFGLEARETSRDVSFCAHA
ILSDDTLVIPDATLDPRFAGNPLVTGAPGIRFYAGHPLALPDGTNLGTLCLIDTRPREIDATDLSHLRDLANLAEREVAA
VQLATLDSLTALSNRRGFEMLSQQALNACRRRGLPASLLFFDLDGFKQINDRFGHAEGDRALVLFARSLTTVLREMDVIG
RLGGDEFVALVMSEQLDVQALVERLRKDLGARGRQAGLEYEIRFSVGHVDYDPRDEPSVARLLAESDLRMYADKSRMKSR
AAPH

Sequences:

>Translated_324_residues
MQIAPLPVNEASRLARLHGLDLLDTPDEERFDRIARLARRIFDVPIALVSLIDANRQWFKSCFGLEARETSRDVSFCAHA
ILSDDTLVIPDATLDPRFAGNPLVTGAPGIRFYAGHPLALPDGTNLGTLCLIDTRPREIDATDLSHLRDLANLAEREVAA
VQLATLDSLTALSNRRGFEMLSQQALNACRRRGLPASLLFFDLDGFKQINDRFGHAEGDRALVLFARSLTTVLREMDVIG
RLGGDEFVALVMSEQLDVQALVERLRKDLGARGRQAGLEYEIRFSVGHVDYDPRDEPSVARLLAESDLRMYADKSRMKSR
AAPH
>Mature_324_residues
MQIAPLPVNEASRLARLHGLDLLDTPDEERFDRIARLARRIFDVPIALVSLIDANRQWFKSCFGLEARETSRDVSFCAHA
ILSDDTLVIPDATLDPRFAGNPLVTGAPGIRFYAGHPLALPDGTNLGTLCLIDTRPREIDATDLSHLRDLANLAEREVAA
VQLATLDSLTALSNRRGFEMLSQQALNACRRRGLPASLLFFDLDGFKQINDRFGHAEGDRALVLFARSLTTVLREMDVIG
RLGGDEFVALVMSEQLDVQALVERLRKDLGARGRQAGLEYEIRFSVGHVDYDPRDEPSVARLLAESDLRMYADKSRMKSR
AAPH

Specific function: Catalyzes the condensation of two GTP molecules to the cyclic dinucleotide di-GMP (c-di-GMP), which acts as a secondary messenger (Probable). Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87081977, Length=268, Percent_Identity=31.7164179104478, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1786584, Length=171, Percent_Identity=35.672514619883, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87081974, Length=177, Percent_Identity=31.0734463276836, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI145693134, Length=160, Percent_Identity=31.25, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788381, Length=140, Percent_Identity=37.1428571428571, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082007, Length=177, Percent_Identity=31.638418079096, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87081881, Length=157, Percent_Identity=31.8471337579618, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787541, Length=153, Percent_Identity=30.0653594771242, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787802, Length=166, Percent_Identity=27.710843373494, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR003018 [H]

Pfam domain/function: PF01590 GAF; PF00990 GGDEF [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 36015; Mature: 36015

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIAPLPVNEASRLARLHGLDLLDTPDEERFDRIARLARRIFDVPIALVSLIDANRQWFK
CCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
SCFGLEARETSRDVSFCAHAILSDDTLVIPDATLDPRFAGNPLVTGAPGIRFYAGHPLAL
HHHCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEECCCCCEEECCCCEEC
PDGTNLGTLCLIDTRPREIDATDLSHLRDLANLAEREVAAVQLATLDSLTALSNRRGFEM
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LSQQALNACRRRGLPASLLFFDLDGFKQINDRFGHAEGDRALVLFARSLTTVLREMDVIG
HHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHH
RLGGDEFVALVMSEQLDVQALVERLRKDLGARGRQAGLEYEIRFSVGHVDYDPRDEPSVA
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHCCCCEEEEEEECCCCCCCCCCHHHH
RLLAESDLRMYADKSRMKSRAAPH
HHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQIAPLPVNEASRLARLHGLDLLDTPDEERFDRIARLARRIFDVPIALVSLIDANRQWFK
CCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
SCFGLEARETSRDVSFCAHAILSDDTLVIPDATLDPRFAGNPLVTGAPGIRFYAGHPLAL
HHHCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEECCCCCEEECCCCEEC
PDGTNLGTLCLIDTRPREIDATDLSHLRDLANLAEREVAAVQLATLDSLTALSNRRGFEM
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LSQQALNACRRRGLPASLLFFDLDGFKQINDRFGHAEGDRALVLFARSLTTVLREMDVIG
HHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHH
RLGGDEFVALVMSEQLDVQALVERLRKDLGARGRQAGLEYEIRFSVGHVDYDPRDEPSVA
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHCCCCEEEEEEECCCCCCCCCCHHHH
RLLAESDLRMYADKSRMKSRAAPH
HHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]