Click here to switch to the map view.

The map label for this gene is uxuR [H]

Identifier: 238027399

GI number: 238027399

Start: 1971706

End: 1972452

Strand: Reverse

Name: uxuR [H]

Synonym: bglu_1g17950

Alternate gene names: 238027399

Gene position: 1972452-1971706 (Counterclockwise)

Preceding gene: 238027400

Following gene: 238027395

Centisome position: 50.49

GC content: 70.41

Gene sequence:

>747_bases
ATGCCGATCCAGCCCATCCAGAACCGCCGTCTCTACCAGCAGATCGCCGACCAGCTGCGCGCGATGATCGAATCGGGAGG
CTTTCCGCCGGGCAGCTACCTGCCGCCCGAGCGCGAGCTGGCGGCGCAGTTCGGCGTCTCGCGTACCTCGGTGCGCGAGG
CGCTGATCGCGCTGGAGGTGGTCGGCCTGGTGTCGGTGCGGGTCGGCGACGGCGTCTCGGTGCGCCCGCGCCCGGCCGCG
GCGCAGACGCCGGAGCTGCCGCGTGCGAGCCGGCTCGAGGTGGATCCCGAACTCGGCATCGAGATCGATCCCGACGCGGA
GATCGCGCCGTTCTCGCTGCTGCAGGCGCGCAAGCTGATCGAGCCGGAGGCGGCCGGCCTCGCGGCCGTCAATGCGTCCG
ACGCGCAGCTCGACGCGATCCGCGAGGCGTTCCTGCGCAACCAGCAGGACAACCGCCGCGGCTCGACCACCCATCCCGGC
GACCGCCTGTTCCATATCCGCATCGCCGAGGCGAGCGGCAACGATGCCTACGCGATGATGATCCGGCAGATGCTCGCGCA
TCGCTACGATCCGCTGTTCCAGCGCCTGCAGCGGCTCTATACGCCGCGTGACATGCCGCATCGCTCCGAGCTCGAGCATC
GCGCGATCCTCGACGCGCTGGCATCGCGCGACGCAAAGGGCGCGCGGCGCGCGATGCTCACGCATCTGAACTCGGTGATC
CGGATCTTCTCGCGGCAGTCGGCCTAG

Upstream 100 bases:

>100_bases
GCGCCAACAGGTTAGAATCGCCGTCCGGTTCACGTTCGCCCGCCCGGCCGGCGGCGGGCGGCGAACGCTTTCCAATCCGA
TGCTCCTCGCCCGCGCCAGC

Downstream 100 bases:

>100_bases
CGCGGCTCAGGCGGCGGGCCGCGCCAGCAGCAGCACCGTCAGCGAACGCACGCCCTGGGCGCCCTGGATCAGCACGCCCT
CGATGTCGGCCGTTGCCGAG

Product: GntR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MPIQPIQNRRLYQQIADQLRAMIESGGFPPGSYLPPERELAAQFGVSRTSVREALIALEVVGLVSVRVGDGVSVRPRPAA
AQTPELPRASRLEVDPELGIEIDPDAEIAPFSLLQARKLIEPEAAGLAAVNASDAQLDAIREAFLRNQQDNRRGSTTHPG
DRLFHIRIAEASGNDAYAMMIRQMLAHRYDPLFQRLQRLYTPRDMPHRSELEHRAILDALASRDAKGARRAMLTHLNSVI
RIFSRQSA

Sequences:

>Translated_248_residues
MPIQPIQNRRLYQQIADQLRAMIESGGFPPGSYLPPERELAAQFGVSRTSVREALIALEVVGLVSVRVGDGVSVRPRPAA
AQTPELPRASRLEVDPELGIEIDPDAEIAPFSLLQARKLIEPEAAGLAAVNASDAQLDAIREAFLRNQQDNRRGSTTHPG
DRLFHIRIAEASGNDAYAMMIRQMLAHRYDPLFQRLQRLYTPRDMPHRSELEHRAILDALASRDAKGARRAMLTHLNSVI
RIFSRQSA
>Mature_247_residues
PIQPIQNRRLYQQIADQLRAMIESGGFPPGSYLPPERELAAQFGVSRTSVREALIALEVVGLVSVRVGDGVSVRPRPAAA
QTPELPRASRLEVDPELGIEIDPDAEIAPFSLLQARKLIEPEAAGLAAVNASDAQLDAIREAFLRNQQDNRRGSTTHPGD
RLFHIRIAEASGNDAYAMMIRQMLAHRYDPLFQRLQRLYTPRDMPHRSELEHRAILDALASRDAKGARRAMLTHLNSVIR
IFSRQSA

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=243, Percent_Identity=34.9794238683128, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI87082208, Length=246, Percent_Identity=34.5528455284553, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1790032, Length=240, Percent_Identity=32.5, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789621, Length=240, Percent_Identity=31.25, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786303, Length=250, Percent_Identity=29.6, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1789353, Length=238, Percent_Identity=24.3697478991597, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27609; Mature: 27478

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS50949 HTH_GNTR ; PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIQPIQNRRLYQQIADQLRAMIESGGFPPGSYLPPERELAAQFGVSRTSVREALIALEV
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
VGLVSVRVGDGVSVRPRPAAAQTPELPRASRLEVDPELGIEIDPDAEIAPFSLLQARKLI
HHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHC
EPEAAGLAAVNASDAQLDAIREAFLRNQQDNRRGSTTHPGDRLFHIRIAEASGNDAYAMM
CCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHH
IRQMLAHRYDPLFQRLQRLYTPRDMPHRSELEHRAILDALASRDAKGARRAMLTHLNSVI
HHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RIFSRQSA
HHHHHCCC
>Mature Secondary Structure 
PIQPIQNRRLYQQIADQLRAMIESGGFPPGSYLPPERELAAQFGVSRTSVREALIALEV
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
VGLVSVRVGDGVSVRPRPAAAQTPELPRASRLEVDPELGIEIDPDAEIAPFSLLQARKLI
HHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHC
EPEAAGLAAVNASDAQLDAIREAFLRNQQDNRRGSTTHPGDRLFHIRIAEASGNDAYAMM
CCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHH
IRQMLAHRYDPLFQRLQRLYTPRDMPHRSELEHRAILDALASRDAKGARRAMLTHLNSVI
HHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RIFSRQSA
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]