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The map label for this gene is hflK [H]

Identifier: 238027078

GI number: 238027078

Start: 1603233

End: 1604645

Strand: Direct

Name: hflK [H]

Synonym: bglu_1g14570

Alternate gene names: 238027078

Gene position: 1603233-1604645 (Clockwise)

Preceding gene: 238027077

Following gene: 238027079

Centisome position: 41.04

GC content: 69.71

Gene sequence:

>1413_bases
GTGAACGATTACAACGAGCGGAGTACCTGGCTGCGCAAGCGTCCGATGCTGTCGATCAACGACCCTCGCTGGGGTCGCGG
CGGCGGCAATGACGACAAGCCCCGCGGCAACGAACCGAAGCGCCCGCAGTCCGACGGCGACGGTCCGCCCGACCTCGATG
AAATGTGGCGCAACTTCAACCGCCGTCTGTCCGGCCTGTTCGGCGGCAAGGGCGGTGGCGGCGGCAATCGCGGCCTGCGC
CCCGACAATGGGCGCGCCGCGCGGGTCGGCGTGGGCATCGTCATCGGCGTGCTGGTCGCGGTGTACGCGGGCAGCGGCAT
CTTCATCGTGCCGGACGGCCAGACGGGCGTCGTGCTGCAGTTCGGCGAATATCGCGGCACGGTGGATCAAGGCGTGCATT
GGCGCCTGCCCTATCCGTTCGAATCGCACGAAGTGGTCGACACCTCTCAGATGCACGCCACCGAGATCGGCCGTAACAAC
GTGGTGCGCCCCGCGAACGTGAAGGACGCCTCGATGCTCACGCGCGACGGCGACATCGTCGATGTGCGCTTCATCGTCCA
GTACCGGATTCGCTCCGCCACCGACTATCTGTTCCGCACCGTCGATCCCGAACTCACCGTGCGCCAGTCCGCGCAGGCTG
CGATTCGCCGCATCGTCGGCGCGCAGGCGGCGAGCGACGTGATCGACTCGGATCGCGACGCGCTGCGCGATGCGCTGATG
CAGGCGATCCAGCACGATCTCGACCGCGACCAGACCGGCCTCGTGGTGACCAACGTCGTGATCCAGGCCGCGCAGCTGCC
CGAGCAGGTGCAGGCCGCCACCGACGAAGTGGCCAAGGCGCGCCAGCAGGGCGAGGCGGCCAAGAACGCCGCGCAGGCCT
ACGCCGACGGCTTGCTGCCGCGCGCGCGCGGCGATGCGGCCAAGCTGATCGAAGACGCGAAGGCCTACGCGGACCGCGTC
GTCACGCAGGCGCAGGGTGACGCGGACCGCTACAAGCAGGTCTACGCGCAGTACGAGAAGGCGCCTGCCGTCGTGCGCGA
GCGCATGTATCTCGACACCATGCAGGAAATCTACTCGAAGGCGATCAAGGTCTACGTCGGCAGCAAGGCCGGCAACAGCG
TGGTCTACCTGCCGCTCGACAAGATCGTCGAGCAGCAGCGCCAGCACGCGGCCGACGCCGCCGCGAGTTCGACCGCGCCG
GCCGGCGCGGCGCCGGCGAACGGCGCCGACATGAACGGCGCGGCCGGCGGTAACGCCCAGGCGTCCGGCTCGAATCCGCC
CGCGGCTTCGGCCGGTTCGTCGGCCGCAACGGCCGCGAGCCCGGCCAGTGCCGCCAGCGATGCGCCGGGCAACGAGGCGC
TGCGCTCGCGCGACGCGCTGCGCAGCCGCTCGCGCGAAGACGATCTGCAGTAA

Upstream 100 bases:

>100_bases
CGGGCTGGCCGAACCGCGCGACGACCACACGGTTTCCGAACACGGGCACTAGCCGGCCGCTGGCCGGACAGTCGACGCCC
AATCTGGTGAACAAACTCAG

Downstream 100 bases:

>100_bases
CGGGGAACGCCAGACATGAATCGAATCGTTGCGCTCGTCATTGCGCTCGTCATCGTCGCGTTCGTCGCGTCGTCCACCGT
GTTCGTCGTCGATCCGAGCC

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MNDYNERSTWLRKRPMLSINDPRWGRGGGNDDKPRGNEPKRPQSDGDGPPDLDEMWRNFNRRLSGLFGGKGGGGGNRGLR
PDNGRAARVGVGIVIGVLVAVYAGSGIFIVPDGQTGVVLQFGEYRGTVDQGVHWRLPYPFESHEVVDTSQMHATEIGRNN
VVRPANVKDASMLTRDGDIVDVRFIVQYRIRSATDYLFRTVDPELTVRQSAQAAIRRIVGAQAASDVIDSDRDALRDALM
QAIQHDLDRDQTGLVVTNVVIQAAQLPEQVQAATDEVAKARQQGEAAKNAAQAYADGLLPRARGDAAKLIEDAKAYADRV
VTQAQGDADRYKQVYAQYEKAPAVVRERMYLDTMQEIYSKAIKVYVGSKAGNSVVYLPLDKIVEQQRQHAADAAASSTAP
AGAAPANGADMNGAAGGNAQASGSNPPAASAGSSAATAASPASAASDAPGNEALRSRDALRSRSREDDLQ

Sequences:

>Translated_470_residues
MNDYNERSTWLRKRPMLSINDPRWGRGGGNDDKPRGNEPKRPQSDGDGPPDLDEMWRNFNRRLSGLFGGKGGGGGNRGLR
PDNGRAARVGVGIVIGVLVAVYAGSGIFIVPDGQTGVVLQFGEYRGTVDQGVHWRLPYPFESHEVVDTSQMHATEIGRNN
VVRPANVKDASMLTRDGDIVDVRFIVQYRIRSATDYLFRTVDPELTVRQSAQAAIRRIVGAQAASDVIDSDRDALRDALM
QAIQHDLDRDQTGLVVTNVVIQAAQLPEQVQAATDEVAKARQQGEAAKNAAQAYADGLLPRARGDAAKLIEDAKAYADRV
VTQAQGDADRYKQVYAQYEKAPAVVRERMYLDTMQEIYSKAIKVYVGSKAGNSVVYLPLDKIVEQQRQHAADAAASSTAP
AGAAPANGADMNGAAGGNAQASGSNPPAASAGSSAATAASPASAASDAPGNEALRSRDALRSRSREDDLQ
>Mature_470_residues
MNDYNERSTWLRKRPMLSINDPRWGRGGGNDDKPRGNEPKRPQSDGDGPPDLDEMWRNFNRRLSGLFGGKGGGGGNRGLR
PDNGRAARVGVGIVIGVLVAVYAGSGIFIVPDGQTGVVLQFGEYRGTVDQGVHWRLPYPFESHEVVDTSQMHATEIGRNN
VVRPANVKDASMLTRDGDIVDVRFIVQYRIRSATDYLFRTVDPELTVRQSAQAAIRRIVGAQAASDVIDSDRDALRDALM
QAIQHDLDRDQTGLVVTNVVIQAAQLPEQVQAATDEVAKARQQGEAAKNAAQAYADGLLPRARGDAAKLIEDAKAYADRV
VTQAQGDADRYKQVYAQYEKAPAVVRERMYLDTMQEIYSKAIKVYVGSKAGNSVVYLPLDKIVEQQRQHAADAAASSTAP
AGAAPANGADMNGAAGGNAQASGSNPPAASAGSSAATAASPASAASDAPGNEALRSRDALRSRSREDDLQ

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=287, Percent_Identity=29.2682926829268, Blast_Score=158, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 50308; Mature: 50308

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDYNERSTWLRKRPMLSINDPRWGRGGGNDDKPRGNEPKRPQSDGDGPPDLDEMWRNFN
CCCCHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
RRLSGLFGGKGGGGGNRGLRPDNGRAARVGVGIVIGVLVAVYAGSGIFIVPDGQTGVVLQ
HHHHHHCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEE
FGEYRGTVDQGVHWRLPYPFESHEVVDTSQMHATEIGRNNVVRPANVKDASMLTRDGDIV
ECCCCCCHHCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCEE
DVRFIVQYRIRSATDYLFRTVDPELTVRQSAQAAIRRIVGAQAASDVIDSDRDALRDALM
EHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
QAIQHDLDRDQTGLVVTNVVIQAAQLPEQVQAATDEVAKARQQGEAAKNAAQAYADGLLP
HHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RARGDAAKLIEDAKAYADRVVTQAQGDADRYKQVYAQYEKAPAVVRERMYLDTMQEIYSK
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIKVYVGSKAGNSVVYLPLDKIVEQQRQHAADAAASSTAPAGAAPANGADMNGAAGGNAQ
HHEEEECCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
ASGSNPPAASAGSSAATAASPASAASDAPGNEALRSRDALRSRSREDDLQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNDYNERSTWLRKRPMLSINDPRWGRGGGNDDKPRGNEPKRPQSDGDGPPDLDEMWRNFN
CCCCHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
RRLSGLFGGKGGGGGNRGLRPDNGRAARVGVGIVIGVLVAVYAGSGIFIVPDGQTGVVLQ
HHHHHHCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEE
FGEYRGTVDQGVHWRLPYPFESHEVVDTSQMHATEIGRNNVVRPANVKDASMLTRDGDIV
ECCCCCCHHCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCEE
DVRFIVQYRIRSATDYLFRTVDPELTVRQSAQAAIRRIVGAQAASDVIDSDRDALRDALM
EHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
QAIQHDLDRDQTGLVVTNVVIQAAQLPEQVQAATDEVAKARQQGEAAKNAAQAYADGLLP
HHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RARGDAAKLIEDAKAYADRVVTQAQGDADRYKQVYAQYEKAPAVVRERMYLDTMQEIYSK
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIKVYVGSKAGNSVVYLPLDKIVEQQRQHAADAAASSTAPAGAAPANGADMNGAAGGNAQ
HHEEEECCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
ASGSNPPAASAGSSAATAASPASAASDAPGNEALRSRDALRSRSREDDLQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]