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The map label for this gene is hflC [H]

Identifier: 238027079

GI number: 238027079

Start: 1604661

End: 1605563

Strand: Direct

Name: hflC [H]

Synonym: bglu_1g14580

Alternate gene names: 238027079

Gene position: 1604661-1605563 (Clockwise)

Preceding gene: 238027078

Following gene: 238027080

Centisome position: 41.08

GC content: 69.77

Gene sequence:

>903_bases
ATGAATCGAATCGTTGCGCTCGTCATTGCGCTCGTCATCGTCGCGTTCGTCGCGTCGTCCACCGTGTTCGTCGTCGATCC
GAGCCATGCCGCGATCGTCTCCGCGCGCGGTGACGGCGAGCCGACCGTGTTCGGTCCCGGCCTGCACGCGAAACTGCCGC
CGCCGCTGCAGACCGCGGTGATGGTCGACACGCGGATCCAGACGCTCGACTGGGCCGATCCGCAGAGTTGCACGACCTCC
GACAAGCAGGACCTGCTGGTCAGCCCGACCGTGCGCTACCGGATCGCCGATCCGCTGAAGTATTACGAGAAGACCGAGGG
CGGCGTGCGCGATGCGCTCGATCCGCTGCTGAGCTCGCTGAAGGACGCGCTCGCGCAGTCGTTCGCGAGCCGTACGCTGG
CCGAGGCGATCGGCGCGCAGCAGGCCATCGCCAACGACGCGAAGCGCACGCTGCAGGCGGCGGCCACGCCCTATGGCGTC
GAGATCGTCGACGTCGCGCTGCTGCGCATCGACCTGCCGGCCGCCGCGACCGAGGCCGCCTATCGCCGCATGGCGGCGCT
CGAGCGCGAGCGCGCCGACGCCGAGCGCGCCGAGGGGGCGGCGGCCGCCGAACGCATCAAGGCCGAGGCGGCGCGCCAGC
AGCAGCAGATTCTCGCGGACGCCTATCAGTCGGCACAGACGATCAAGGGCGAGGGCGACGCCAAGGCCGCTCAGATCGCC
GGTGACGCGTTCGGCCGCGATCCGCAGTTCTACCAGTTCTACGCGAGCCTGCAGGCGTACCGGAACACGTTCCACGCCAA
CGACGTGATCGTCGTCGATCCGGACAGCGAATTCTTCCGCTTCATGCGCGGCCCGACGGGCGGCACGGCCGCCGCGCCGG
CGTCCGCTTCCCGCAAACACTGA

Upstream 100 bases:

>100_bases
TGCCGCCAGCGATGCGCCGGGCAACGAGGCGCTGCGCTCGCGCGACGCGCTGCGCAGCCGCTCGCGCGAAGACGATCTGC
AGTAACGGGGAACGCCAGAC

Downstream 100 bases:

>100_bases
CGTACAAGGGGCGCCGCCGCGCGCGGCGCCGTCGATACCGCATGGATCTGGCCGGTTCGCTGTTGCTCGCTCTCGCGCTG
ATGCTGATCGTCGAAGGGGC

Product: ftsH protease activity modulator HflC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MNRIVALVIALVIVAFVASSTVFVVDPSHAAIVSARGDGEPTVFGPGLHAKLPPPLQTAVMVDTRIQTLDWADPQSCTTS
DKQDLLVSPTVRYRIADPLKYYEKTEGGVRDALDPLLSSLKDALAQSFASRTLAEAIGAQQAIANDAKRTLQAAATPYGV
EIVDVALLRIDLPAAATEAAYRRMAALERERADAERAEGAAAAERIKAEAARQQQQILADAYQSAQTIKGEGDAKAAQIA
GDAFGRDPQFYQFYASLQAYRNTFHANDVIVVDPDSEFFRFMRGPTGGTAAAPASASRKH

Sequences:

>Translated_300_residues
MNRIVALVIALVIVAFVASSTVFVVDPSHAAIVSARGDGEPTVFGPGLHAKLPPPLQTAVMVDTRIQTLDWADPQSCTTS
DKQDLLVSPTVRYRIADPLKYYEKTEGGVRDALDPLLSSLKDALAQSFASRTLAEAIGAQQAIANDAKRTLQAAATPYGV
EIVDVALLRIDLPAAATEAAYRRMAALERERADAERAEGAAAAERIKAEAARQQQQILADAYQSAQTIKGEGDAKAAQIA
GDAFGRDPQFYQFYASLQAYRNTFHANDVIVVDPDSEFFRFMRGPTGGTAAAPASASRKH
>Mature_300_residues
MNRIVALVIALVIVAFVASSTVFVVDPSHAAIVSARGDGEPTVFGPGLHAKLPPPLQTAVMVDTRIQTLDWADPQSCTTS
DKQDLLVSPTVRYRIADPLKYYEKTEGGVRDALDPLLSSLKDALAQSFASRTLAEAIGAQQAIANDAKRTLQAAATPYGV
EIVDVALLRIDLPAAATEAAYRRMAALERERADAERAEGAAAAERIKAEAARQQQQILADAYQSAQTIKGEGDAKAAQIA
GDAFGRDPQFYQFYASLQAYRNTFHANDVIVVDPDSEFFRFMRGPTGGTAAAPASASRKH

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=321, Percent_Identity=33.6448598130841, Blast_Score=158, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 32102; Mature: 32102

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIVALVIALVIVAFVASSTVFVVDPSHAAIVSARGDGEPTVFGPGLHAKLPPPLQTAV
CHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEECCCCCCCEECCCCCCCCCCCHHHHE
MVDTRIQTLDWADPQSCTTSDKQDLLVSPTVRYRIADPLKYYEKTEGGVRDALDPLLSSL
EEHHHHHCCCCCCCCCCCCCCCCCEEECCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHH
KDALAQSFASRTLAEAIGAQQAIANDAKRTLQAAATPYGVEIVDVALLRIDLPAAATEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHH
YRRMAALERERADAERAEGAAAAERIKAEAARQQQQILADAYQSAQTIKGEGDAKAAQIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
GDAFGRDPQFYQFYASLQAYRNTFHANDVIVVDPDSEFFRFMRGPTGGTAAAPASASRKH
HHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNRIVALVIALVIVAFVASSTVFVVDPSHAAIVSARGDGEPTVFGPGLHAKLPPPLQTAV
CHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEECCCCCCCEECCCCCCCCCCCHHHHE
MVDTRIQTLDWADPQSCTTSDKQDLLVSPTVRYRIADPLKYYEKTEGGVRDALDPLLSSL
EEHHHHHCCCCCCCCCCCCCCCCCEEECCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHH
KDALAQSFASRTLAEAIGAQQAIANDAKRTLQAAATPYGVEIVDVALLRIDLPAAATEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHH
YRRMAALERERADAERAEGAAAAERIKAEAARQQQQILADAYQSAQTIKGEGDAKAAQIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
GDAFGRDPQFYQFYASLQAYRNTFHANDVIVVDPDSEFFRFMRGPTGGTAAAPASASRKH
HHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]