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The map label for this gene is rumA [H]

Identifier: 238027066

GI number: 238027066

Start: 1590103

End: 1591497

Strand: Direct

Name: rumA [H]

Synonym: bglu_1g14450

Alternate gene names: 238027066

Gene position: 1590103-1591497 (Clockwise)

Preceding gene: 238027064

Following gene: 238027068

Centisome position: 40.7

GC content: 67.03

Gene sequence:

>1395_bases
GTGTCCGAAGCCGTCCCCACTCCCGCGCGCAAATCCCGCAACGCGCCCGTCGCGCACGTCAGTGCGCCCATCGAGATCGA
ATCGCTCGACATGGATGCACGCGGCGTCGGCCGCCTCGTGAACGAGGACGGCGAGTTCGGCAAGGTGATTTTCGTCGAGG
GCGCGCTGCCGGGCGAGCGCGTCACCTATTCGAGCTATCGCCGCAAGCCCAGCTACGAGCAGGCCACGGTGGTCGATATT
CTGCGCCCGAGCGTGATGCGCGCGCAGCCGAAATGCGAATTCTTCGGCACCTGCGGCGGCTGCTCGATGCAGCATCTCGA
CGTGCGTGCCCAAGTGGCGATCAAGCAGCGCGTGCTTGAGGACAATCTCTGGCATTTGTCGAAGCTGCGCGCGCAGACGA
TGTTCTCGCCGATCCACGGCCCGGCCTGGGGCTACCGCTATCGCGCGCGGCTGACCGTGCGCGACGTCGCGAAGAAGGGC
GGCGTGCTGGTGGGTTTCCACGAGAAGAAGAGCAGCTACGTGGCCGACATGACGAGCTGCGAGGTGCTGCCGCCGCACGT
GTCCGCCATGCTCGTGCCGCTGCGCGAACTCGTTGCGGGGCTGTCGATCCGGGATCGGATGCCGCAGATCGAGCTCGCGG
TCGGGTCGAGCGTGACGGCGCTCGTGCTGCGCGTGCTCGAGCCGATCAATGCCGCCGACGAAGCGCTGCTGCGCGCCTTC
GCCGATGCGCATCAGGTGCAGTTCTGGCTGCAGCCGAAGGGCCCGGACTCGGTATTCCCGTTCTACCCGCTCGACCGGTC
GCTCGACTACACGCTGCCGGAATTCAATATCCGCATGCCGTTCAAGCCGACCGACTTCACTCAGGTCAATCACCAGATCA
ATCGCGTGCTGGTGGGCCGCGCGCTGCGCCTGCTCGCGCCGCGGCGCGGCGACCGCGTGCTGGACCTGTTCTGCGGGATC
GGCAATTTCACGCTGCCGCTTGCGCGGCTGTCGCGCGAGGTGGTCGGCATCGAGGGCAGCGAGGTGCTGACCACGCGCGC
GCTCGAGAACGCGAAGGCAAACGGCGTCGATGCGCATACCTCGTTCGCCTGCCGAAACTTGTTCGAGGTCACGGCCGACG
ATCTGCGTGCGCTTGGCGGGTTCGATAAGTTCCTCGTCGATCCGCCGCGTGAAGGCGCGCTCGCGGTGTCGAAGGCGCTC
GCGGAAATCGCGCAGAGCGGCGACGGCCCGCTGCCGCAGCGGATCGTCTACGTGTCGTGCAATCCCGCGACGCTCGCGCG
TGACGCGGGCCTGCTGGTTCACGAGGCCGGCTATCGGCTGCGCGGCGCGGGCGTGGTGAACATGTTCCCGAATACGTCGC
ACGTCGAATCGATCGCGGTGTTCGAACGCGATTGA

Upstream 100 bases:

>100_bases
ATTGGATGTTCCAGTCGATCAAGCGCATATCAATCTCCGATGGCGCACGTTCATTCGTCTACAATCTCGCCTTCCCCCAA
ACGATCGTCAGGAAAAGCTG

Downstream 100 bases:

>100_bases
GCGGCCGGATCGCCGTCCGCGCCGCGCCGAGCGAGCGCTCATAAAAAAACCGGCCCGATCATCGGGCCGGTTTTTCGTGG
CGAATCCGGGGAGTGATGAC

Product: 23S rRNA m(5)U1939 methyltransferase

Products: NA

Alternate protein names: 23S rRNA(M-5-U1939)-methyltransferase [H]

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MSEAVPTPARKSRNAPVAHVSAPIEIESLDMDARGVGRLVNEDGEFGKVIFVEGALPGERVTYSSYRRKPSYEQATVVDI
LRPSVMRAQPKCEFFGTCGGCSMQHLDVRAQVAIKQRVLEDNLWHLSKLRAQTMFSPIHGPAWGYRYRARLTVRDVAKKG
GVLVGFHEKKSSYVADMTSCEVLPPHVSAMLVPLRELVAGLSIRDRMPQIELAVGSSVTALVLRVLEPINAADEALLRAF
ADAHQVQFWLQPKGPDSVFPFYPLDRSLDYTLPEFNIRMPFKPTDFTQVNHQINRVLVGRALRLLAPRRGDRVLDLFCGI
GNFTLPLARLSREVVGIEGSEVLTTRALENAKANGVDAHTSFACRNLFEVTADDLRALGGFDKFLVDPPREGALAVSKAL
AEIAQSGDGPLPQRIVYVSCNPATLARDAGLLVHEAGYRLRGAGVVNMFPNTSHVESIAVFERD

Sequences:

>Translated_464_residues
MSEAVPTPARKSRNAPVAHVSAPIEIESLDMDARGVGRLVNEDGEFGKVIFVEGALPGERVTYSSYRRKPSYEQATVVDI
LRPSVMRAQPKCEFFGTCGGCSMQHLDVRAQVAIKQRVLEDNLWHLSKLRAQTMFSPIHGPAWGYRYRARLTVRDVAKKG
GVLVGFHEKKSSYVADMTSCEVLPPHVSAMLVPLRELVAGLSIRDRMPQIELAVGSSVTALVLRVLEPINAADEALLRAF
ADAHQVQFWLQPKGPDSVFPFYPLDRSLDYTLPEFNIRMPFKPTDFTQVNHQINRVLVGRALRLLAPRRGDRVLDLFCGI
GNFTLPLARLSREVVGIEGSEVLTTRALENAKANGVDAHTSFACRNLFEVTADDLRALGGFDKFLVDPPREGALAVSKAL
AEIAQSGDGPLPQRIVYVSCNPATLARDAGLLVHEAGYRLRGAGVVNMFPNTSHVESIAVFERD
>Mature_463_residues
SEAVPTPARKSRNAPVAHVSAPIEIESLDMDARGVGRLVNEDGEFGKVIFVEGALPGERVTYSSYRRKPSYEQATVVDIL
RPSVMRAQPKCEFFGTCGGCSMQHLDVRAQVAIKQRVLEDNLWHLSKLRAQTMFSPIHGPAWGYRYRARLTVRDVAKKGG
VLVGFHEKKSSYVADMTSCEVLPPHVSAMLVPLRELVAGLSIRDRMPQIELAVGSSVTALVLRVLEPINAADEALLRAFA
DAHQVQFWLQPKGPDSVFPFYPLDRSLDYTLPEFNIRMPFKPTDFTQVNHQINRVLVGRALRLLAPRRGDRVLDLFCGIG
NFTLPLARLSREVVGIEGSEVLTTRALENAKANGVDAHTSFACRNLFEVTADDLRALGGFDKFLVDPPREGALAVSKALA
EIAQSGDGPLPQRIVYVSCNPATLARDAGLLVHEAGYRLRGAGVVNMFPNTSHVESIAVFERD

Specific function: Catalyzes the formation of 5-methyl-uridine at position 1939 (M-5-U1939) in 23S rRNA [H]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Escherichia coli, GI1789148, Length=443, Percent_Identity=36.117381489842, Blast_Score=259, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24666579, Length=210, Percent_Identity=31.4285714285714, Blast_Score=82, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280 [H]

Pfam domain/function: PF05958 tRNA_U5-meth_tr [H]

EC number: =2.1.1.190 [H]

Molecular weight: Translated: 51063; Mature: 50932

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: PS50926 TRAM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAVPTPARKSRNAPVAHVSAPIEIESLDMDARGVGRLVNEDGEFGKVIFVEGALPGER
CCCCCCCCHHHCCCCCEEEECCCEEEEECCCCHHHHHHHHCCCCCCCEEEEEECCCCCCC
VTYSSYRRKPSYEQATVVDILRPSVMRAQPKCEFFGTCGGCSMQHLDVRAQVAIKQRVLE
EEHHHHCCCCCCCHHHHHHHHCCHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHH
DNLWHLSKLRAQTMFSPIHGPAWGYRYRARLTVRDVAKKGGVLVGFHEKKSSYVADMTSC
HHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHHHHHHHCCEEEEEECCCCCHHHHCCCC
EVLPPHVSAMLVPLRELVAGLSIRDRMPQIELAVGSSVTALVLRVLEPINAADEALLRAF
CCCCHHHHHHHHHHHHHHCCCCHHHCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHH
ADAHQVQFWLQPKGPDSVFPFYPLDRSLDYTLPEFNIRMPFKPTDFTQVNHQINRVLVGR
HHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHH
ALRLLAPRRGDRVLDLFCGIGNFTLPLARLSREVVGIEGSEVLTTRALENAKANGVDAHT
HHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHH
SFACRNLFEVTADDLRALGGFDKFLVDPPREGALAVSKALAEIAQSGDGPLPQRIVYVSC
HHHHHHHHHHCHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEC
NPATLARDAGLLVHEAGYRLRGAGVVNMFPNTSHVESIAVFERD
CCHHHHHCCCEEEECCCCEEECCCEEEECCCCCCCCEEEEEECC
>Mature Secondary Structure 
SEAVPTPARKSRNAPVAHVSAPIEIESLDMDARGVGRLVNEDGEFGKVIFVEGALPGER
CCCCCCCHHHCCCCCEEEECCCEEEEECCCCHHHHHHHHCCCCCCCEEEEEECCCCCCC
VTYSSYRRKPSYEQATVVDILRPSVMRAQPKCEFFGTCGGCSMQHLDVRAQVAIKQRVLE
EEHHHHCCCCCCCHHHHHHHHCCHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHH
DNLWHLSKLRAQTMFSPIHGPAWGYRYRARLTVRDVAKKGGVLVGFHEKKSSYVADMTSC
HHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHHHHHHHCCEEEEEECCCCCHHHHCCCC
EVLPPHVSAMLVPLRELVAGLSIRDRMPQIELAVGSSVTALVLRVLEPINAADEALLRAF
CCCCHHHHHHHHHHHHHHCCCCHHHCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHH
ADAHQVQFWLQPKGPDSVFPFYPLDRSLDYTLPEFNIRMPFKPTDFTQVNHQINRVLVGR
HHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHH
ALRLLAPRRGDRVLDLFCGIGNFTLPLARLSREVVGIEGSEVLTTRALENAKANGVDAHT
HHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHH
SFACRNLFEVTADDLRALGGFDKFLVDPPREGALAVSKALAEIAQSGDGPLPQRIVYVSC
HHHHHHHHHHCHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEC
NPATLARDAGLLVHEAGYRLRGAGVVNMFPNTSHVESIAVFERD
CCHHHHHCCCEEEECCCCEEECCCEEEECCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA