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The map label for this gene is ndk [H]

Identifier: 238027068

GI number: 238027068

Start: 1592592

End: 1593017

Strand: Direct

Name: ndk [H]

Synonym: bglu_1g14470

Alternate gene names: 238027068

Gene position: 1592592-1593017 (Clockwise)

Preceding gene: 238027066

Following gene: 238027069

Centisome position: 40.77

GC content: 61.03

Gene sequence:

>426_bases
ATGGCAATCGAGCGCACCCTGTCGATCATCAAGCCGGACGCAGTGGCAAAGAACGTGATCGGTCAGATCTACAGCCGTTT
CGAAGGCGCTGGCCTGAAGGTCGTCGCGGCTCGTATGGCGCATCTGTCGCGCGGTGAAGCGGAGCAGTTCTACGCGGTTC
ACGCGGCTCGTCCGTTCTTCAAGGATCTGGTCGACTTCATGATCTCGGGCCCGGTGATGATCCAGGTTCTGGAAGGCGAA
AACGCGATCCAGAAGAACCGCGACCTGATGGGCGCGACCGACCCGAAGAAGGCCGAAGCCGGCACGATTCGCGCCGACTT
CGCCGACAGCATCGATGCCAATGCGGTTCACGGTTCGGACGCGCCGGAAACGGCGGCCGTCGAAATCGGCTTCTTCTTCG
CAGGTCTGAACGTCTACTCGCGCTAA

Upstream 100 bases:

>100_bases
CCTTTCCGAGATGTAAGGGTTCGATCGCAATGATACACGGGAACGTGCTACAATAACGGATTCATTTGAAAACGTAACTT
CTTAATTTCTTGGAGTTTTT

Downstream 100 bases:

>100_bases
GCGGGTAGCGGGTCCGGCGCGTGCGGCAAGGCAGGGCACCATGACGAGCGATACTCCCGTCAATCTCCTCGACTTCGACG
CCGAAGGTCTCGTCGCGTAT

Product: Nucleoside-diphosphate kinase

Products: NA

Alternate protein names: NDK; NDP kinase; Nucleoside-2-P kinase [H]

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MAIERTLSIIKPDAVAKNVIGQIYSRFEGAGLKVVAARMAHLSRGEAEQFYAVHAARPFFKDLVDFMISGPVMIQVLEGE
NAIQKNRDLMGATDPKKAEAGTIRADFADSIDANAVHGSDAPETAAVEIGFFFAGLNVYSR

Sequences:

>Translated_141_residues
MAIERTLSIIKPDAVAKNVIGQIYSRFEGAGLKVVAARMAHLSRGEAEQFYAVHAARPFFKDLVDFMISGPVMIQVLEGE
NAIQKNRDLMGATDPKKAEAGTIRADFADSIDANAVHGSDAPETAAVEIGFFFAGLNVYSR
>Mature_140_residues
AIERTLSIIKPDAVAKNVIGQIYSRFEGAGLKVVAARMAHLSRGEAEQFYAVHAARPFFKDLVDFMISGPVMIQVLEGEN
AIQKNRDLMGATDPKKAEAGTIRADFADSIDANAVHGSDAPETAAVEIGFFFAGLNVYSR

Specific function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate [H]

COG id: COG0105

COG function: function code F; Nucleoside diphosphate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NDK family [H]

Homologues:

Organism=Homo sapiens, GI37693993, Length=132, Percent_Identity=41.6666666666667, Blast_Score=113, Evalue=7e-26,
Organism=Homo sapiens, GI38045913, Length=131, Percent_Identity=40.4580152671756, Blast_Score=112, Evalue=1e-25,
Organism=Homo sapiens, GI4557797, Length=131, Percent_Identity=40.4580152671756, Blast_Score=111, Evalue=2e-25,
Organism=Homo sapiens, GI66392227, Length=131, Percent_Identity=40.4580152671756, Blast_Score=111, Evalue=2e-25,
Organism=Homo sapiens, GI66392205, Length=131, Percent_Identity=40.4580152671756, Blast_Score=111, Evalue=2e-25,
Organism=Homo sapiens, GI4505409, Length=131, Percent_Identity=40.4580152671756, Blast_Score=111, Evalue=2e-25,
Organism=Homo sapiens, GI66392192, Length=131, Percent_Identity=40.4580152671756, Blast_Score=111, Evalue=2e-25,
Organism=Homo sapiens, GI66392203, Length=131, Percent_Identity=40.4580152671756, Blast_Score=111, Evalue=2e-25,
Organism=Homo sapiens, GI4826862, Length=130, Percent_Identity=37.6923076923077, Blast_Score=100, Evalue=7e-22,
Organism=Homo sapiens, GI37574614, Length=138, Percent_Identity=36.231884057971, Blast_Score=85, Evalue=2e-17,
Organism=Homo sapiens, GI7019465, Length=138, Percent_Identity=36.231884057971, Blast_Score=85, Evalue=2e-17,
Organism=Homo sapiens, GI5031951, Length=136, Percent_Identity=35.2941176470588, Blast_Score=80, Evalue=8e-16,
Organism=Homo sapiens, GI30023828, Length=139, Percent_Identity=33.0935251798561, Blast_Score=74, Evalue=3e-14,
Organism=Homo sapiens, GI148839372, Length=129, Percent_Identity=34.1085271317829, Blast_Score=67, Evalue=4e-12,
Organism=Homo sapiens, GI4505413, Length=135, Percent_Identity=31.8518518518519, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788866, Length=141, Percent_Identity=59.5744680851064, Blast_Score=179, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI17506807, Length=130, Percent_Identity=40, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6322783, Length=130, Percent_Identity=41.5384615384615, Blast_Score=118, Evalue=3e-28,
Organism=Drosophila melanogaster, GI45549037, Length=130, Percent_Identity=44.6153846153846, Blast_Score=122, Evalue=6e-29,
Organism=Drosophila melanogaster, GI18860097, Length=134, Percent_Identity=32.089552238806, Blast_Score=73, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001564 [H]

Pfam domain/function: PF00334 NDK [H]

EC number: =2.7.4.6 [H]

Molecular weight: Translated: 15217; Mature: 15085

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00469 NDP_KINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIERTLSIIKPDAVAKNVIGQIYSRFEGAGLKVVAARMAHLSRGEAEQFYAVHAARPFF
CCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHH
KDLVDFMISGPVMIQVLEGENAIQKNRDLMGATDPKKAEAGTIRADFADSIDANAVHGSD
HHHHHHHHCCCEEEEEECCCCHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCC
APETAAVEIGFFFAGLNVYSR
CCCCCEEEHHHHEECCHHCCC
>Mature Secondary Structure 
AIERTLSIIKPDAVAKNVIGQIYSRFEGAGLKVVAARMAHLSRGEAEQFYAVHAARPFF
CCHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHH
KDLVDFMISGPVMIQVLEGENAIQKNRDLMGATDPKKAEAGTIRADFADSIDANAVHGSD
HHHHHHHHCCCEEEEEECCCCHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCC
APETAAVEIGFFFAGLNVYSR
CCCCCEEEHHHHEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA