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The map label for this gene is gcvT [H]

Identifier: 238026645

GI number: 238026645

Start: 1073381

End: 1075870

Strand: Reverse

Name: gcvT [H]

Synonym: bglu_1g09970

Alternate gene names: 238026645

Gene position: 1075870-1073381 (Counterclockwise)

Preceding gene: 238026646

Following gene: 238026644

Centisome position: 27.54

GC content: 73.45

Gene sequence:

>2490_bases
ATGGCCGCCCCGTTCTCCGCCCCGCCCGTGCCGTCCCATGCCCGCGTCGTGATCGTGGGCGGCGGAATCATCGGCTGCTC
GACCGCCTACCATCTCGCCAGGGCCGGCATCACGGACGTGGTGCTGCTCGAACAGGGCCAGCTCTCGTGCGGCACCACCT
GGCACGCGGCCGGCCTGGTGGGTCAGTTGCGCACGCAACGCAGCCTGACGCAGCTGATCCGCTATTCCACCGAGTTGTAT
GCGTCGCTCGAGGCCGAGACCGGCCTCGCCACCGGCTGGAAGCGCTGCGGCTCGCTGTCGGTGGCGCGCACGGCCGAGCG
TCTCACGCAATTGAAGCGCACGGCCGCCATGGCGCGCGCCTACGGCGTCGAATGCGAGCTGATCGATGCGCGCGCGGCCG
GCGCGCTGTGGCCCGCGATGCGAACCGATGATCTGGCCGGCGCGGCCTGGCTGCCCGGCGACGGCAAGGCGAACCCCACC
GACCTCACCCAGTCGCTCGCGCGCGGCGCGCGCCAGCGCGGCGTGCGGATCATCGAGAGCACGCGCGTCACGGCCGTGCT
GAGCGAGCGCACCGGCACGCGCCGCCGCGCGGCCGGCGTGGTGTGGCGCAACAAGGCCGGCGACACCGGCACGCTCGGCG
CCGAATTCGTGGTGAACTGCGCGGGCCAGTGGGCCAAGGGCCTCGGCCGGCTCGCCGACGTCACGGTGCCGCTGCACGCG
GCCGAGCACTACTACATCGTGACCGGCCGGATTCCGGGCACGCACCCGGACCTGCCGGTGATGCGCGACCCCGACGGCTA
CGTCTACTTCAAGGAGGAAGTGGGCGGGCTCGTGATGGGCGGCTTCGAGCCCGACGCGAAGCCGTGGGGCATGGACGGCA
TTCCCGACCAATTCGAATTCCAGCTGCTGCCCGACGACTGGGACCAGTTCGAGATCCTGATGCGCAACGCGCTGCACCGC
GTGCCGGCGCTCGAGACGGCCGAGGTCCGGCAGTTCTACAACGGCCCCGAGTCGTTCACCCCGGACAACCACTTCATCCT
CGGCGAGGCGCCCGAGCTGGCGAACTTCTTCGTCGGCGCGGGCTTCAATTCGATGGGCATCGCCTCGGCGGGCGGCGCCG
GCCGCGCGCTCGCCGAGTGGATCGAGGCGGGCGAGCCGACCCTGGACCTGTGGGCCGTGGACCTGCGCCGCTTCGCGCGC
CTGCACGGCAACGACGCGTGGCTCCACGACCGCGTGAAGGAAACGCTCGGCCTGCACTACGCGATGCCCTGGCCGAACCG
CGAACTCGAGAGCGCGCGCGGCGTGCGGCGCTCGCCGGTCCACGCGCAGCTGCAGGCTGCCGGCGCCTGCTTCGGCAGCC
GGATGGGCTGGGAAATCGTCAACGTGTTCGCGCCGCCGGGCCAGCCGCCGCGCATCGACTACCGCTTCGGCCGGCAGAAC
TGGCACGACTGGAGTGCCGCCGAGCACCGCGCCTGCCGCGAGGCGGTGGCCCTGTTCGATCGCAGCGCGCTGGCCAAGCT
GCTCGTCAAGGGGCGCGACGCCGAAAGCGCGCTGCAGTCGCGCCTGGCCAACGACGTCGCGGTGGCGCCCGGCAGCATCG
TGCGCAGCGGCATCCTCAACACGCGCGGCGGCTACGAGTCCGACGTCGTGCTCGCGCGGCTTGCCGACGATCGCTATCTG
CTGCTCACCGGCACCACGCAGGCCACGCGCGATCTCGACCTGCTCGAGCGTCATCTCGAGGCCGGCGATCGGCGCTGCGT
GGCGCTCGACGTGACGGGGCAATACGCGCTCTTCTCGCTGATCGGCCCGCATGCGCGCGCACTGCTGCAGCGCGTCTCGC
GCGCGGACTTGCGCGATGCCGGGTTCGCGGCCGGCACCTGCCGCGAGATCGAGCTCGGCCACGCCACCGTGCACGCGCTG
CGCCACGCGATCGCCGGCGCGCCGGGCTGGGACCTGCTGGTGCCGGTCGAGTCGGCGGTGCCGGTGCATGCGGCGCTGGT
GCACGCGGGCGCCGCGCTCGGGCTCGTCCAGGCCGGCGAGTACGCGCTCGAATCGCTGCGCATCGAGAATGGCCAGGCGG
CCTGGGGCCGTGAACTGTCGCCAAGCCTCGACCCGTTCGAGGCCGGCCTCGCCGGGCTCTGCAAGCTCGCGATGCCGATA
CCGTTCACGGGCTCGGCGGCGCTTGCCGCGCGCGCCGGGCTACCGTGCCGGCGCCGCGTCGTCGCGCTGCGCGTCGAGGG
CCGGCCCGACGTCACCTTGTGGGGCGGCGAGGCGATCCTGCGCGACGGCGCGGCCGTCGGCCTACTGAGTTCGGCCGGGT
TCGGCCACACGCTCGGCCTGCCGGTCGCGCTCGGCGTGGTGAGTTGCGCGGCCGGCGCGCCCGACCCCACCGAGGGCCGC
TACCAGATCGAACTGGCGGGCGAACGGCTCGCCGCGACGGCGCGCCTGCCGGCGCCGCACGATCCGGCCGGGCTCGGGCG
GCCCGCATGA

Upstream 100 bases:

>100_bases
CCTCGCGCCCGCGGCGAACGCCGCCGCTCGTGGGCGCCGTCGCAAACGTGTCATTTTCAGGCAATACGATGCGTTTTGTT
GCAATCTGTCCAGGCTCGCG

Downstream 100 bases:

>100_bases
GCGCGCCGGCGGCCGCCCCGTCGAGCCCGCCCCCGGGTCGGCCGGCGGGTTCGTCCCGGGCCGGCCGGCGCGGGCGGCAT
CGGGCCGGCGCCGTCTCGTC

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 829; Mature: 828

Protein sequence:

>829_residues
MAAPFSAPPVPSHARVVIVGGGIIGCSTAYHLARAGITDVVLLEQGQLSCGTTWHAAGLVGQLRTQRSLTQLIRYSTELY
ASLEAETGLATGWKRCGSLSVARTAERLTQLKRTAAMARAYGVECELIDARAAGALWPAMRTDDLAGAAWLPGDGKANPT
DLTQSLARGARQRGVRIIESTRVTAVLSERTGTRRRAAGVVWRNKAGDTGTLGAEFVVNCAGQWAKGLGRLADVTVPLHA
AEHYYIVTGRIPGTHPDLPVMRDPDGYVYFKEEVGGLVMGGFEPDAKPWGMDGIPDQFEFQLLPDDWDQFEILMRNALHR
VPALETAEVRQFYNGPESFTPDNHFILGEAPELANFFVGAGFNSMGIASAGGAGRALAEWIEAGEPTLDLWAVDLRRFAR
LHGNDAWLHDRVKETLGLHYAMPWPNRELESARGVRRSPVHAQLQAAGACFGSRMGWEIVNVFAPPGQPPRIDYRFGRQN
WHDWSAAEHRACREAVALFDRSALAKLLVKGRDAESALQSRLANDVAVAPGSIVRSGILNTRGGYESDVVLARLADDRYL
LLTGTTQATRDLDLLERHLEAGDRRCVALDVTGQYALFSLIGPHARALLQRVSRADLRDAGFAAGTCREIELGHATVHAL
RHAIAGAPGWDLLVPVESAVPVHAALVHAGAALGLVQAGEYALESLRIENGQAAWGRELSPSLDPFEAGLAGLCKLAMPI
PFTGSAALAARAGLPCRRRVVALRVEGRPDVTLWGGEAILRDGAAVGLLSSAGFGHTLGLPVALGVVSCAAGAPDPTEGR
YQIELAGERLAATARLPAPHDPAGLGRPA

Sequences:

>Translated_829_residues
MAAPFSAPPVPSHARVVIVGGGIIGCSTAYHLARAGITDVVLLEQGQLSCGTTWHAAGLVGQLRTQRSLTQLIRYSTELY
ASLEAETGLATGWKRCGSLSVARTAERLTQLKRTAAMARAYGVECELIDARAAGALWPAMRTDDLAGAAWLPGDGKANPT
DLTQSLARGARQRGVRIIESTRVTAVLSERTGTRRRAAGVVWRNKAGDTGTLGAEFVVNCAGQWAKGLGRLADVTVPLHA
AEHYYIVTGRIPGTHPDLPVMRDPDGYVYFKEEVGGLVMGGFEPDAKPWGMDGIPDQFEFQLLPDDWDQFEILMRNALHR
VPALETAEVRQFYNGPESFTPDNHFILGEAPELANFFVGAGFNSMGIASAGGAGRALAEWIEAGEPTLDLWAVDLRRFAR
LHGNDAWLHDRVKETLGLHYAMPWPNRELESARGVRRSPVHAQLQAAGACFGSRMGWEIVNVFAPPGQPPRIDYRFGRQN
WHDWSAAEHRACREAVALFDRSALAKLLVKGRDAESALQSRLANDVAVAPGSIVRSGILNTRGGYESDVVLARLADDRYL
LLTGTTQATRDLDLLERHLEAGDRRCVALDVTGQYALFSLIGPHARALLQRVSRADLRDAGFAAGTCREIELGHATVHAL
RHAIAGAPGWDLLVPVESAVPVHAALVHAGAALGLVQAGEYALESLRIENGQAAWGRELSPSLDPFEAGLAGLCKLAMPI
PFTGSAALAARAGLPCRRRVVALRVEGRPDVTLWGGEAILRDGAAVGLLSSAGFGHTLGLPVALGVVSCAAGAPDPTEGR
YQIELAGERLAATARLPAPHDPAGLGRPA
>Mature_828_residues
AAPFSAPPVPSHARVVIVGGGIIGCSTAYHLARAGITDVVLLEQGQLSCGTTWHAAGLVGQLRTQRSLTQLIRYSTELYA
SLEAETGLATGWKRCGSLSVARTAERLTQLKRTAAMARAYGVECELIDARAAGALWPAMRTDDLAGAAWLPGDGKANPTD
LTQSLARGARQRGVRIIESTRVTAVLSERTGTRRRAAGVVWRNKAGDTGTLGAEFVVNCAGQWAKGLGRLADVTVPLHAA
EHYYIVTGRIPGTHPDLPVMRDPDGYVYFKEEVGGLVMGGFEPDAKPWGMDGIPDQFEFQLLPDDWDQFEILMRNALHRV
PALETAEVRQFYNGPESFTPDNHFILGEAPELANFFVGAGFNSMGIASAGGAGRALAEWIEAGEPTLDLWAVDLRRFARL
HGNDAWLHDRVKETLGLHYAMPWPNRELESARGVRRSPVHAQLQAAGACFGSRMGWEIVNVFAPPGQPPRIDYRFGRQNW
HDWSAAEHRACREAVALFDRSALAKLLVKGRDAESALQSRLANDVAVAPGSIVRSGILNTRGGYESDVVLARLADDRYLL
LTGTTQATRDLDLLERHLEAGDRRCVALDVTGQYALFSLIGPHARALLQRVSRADLRDAGFAAGTCREIELGHATVHALR
HAIAGAPGWDLLVPVESAVPVHAALVHAGAALGLVQAGEYALESLRIENGQAAWGRELSPSLDPFEAGLAGLCKLAMPIP
FTGSAALAARAGLPCRRRVVALRVEGRPDVTLWGGEAILRDGAAVGLLSSAGFGHTLGLPVALGVVSCAAGAPDPTEGRY
QIELAGERLAATARLPAPHDPAGLGRPA

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Inner Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=859, Percent_Identity=37.3690337601863, Blast_Score=527, Evalue=1e-149,
Organism=Homo sapiens, GI21361378, Length=859, Percent_Identity=37.3690337601863, Blast_Score=527, Evalue=1e-149,
Organism=Homo sapiens, GI194306651, Length=828, Percent_Identity=35.1449275362319, Blast_Score=490, Evalue=1e-138,
Organism=Homo sapiens, GI24797151, Length=782, Percent_Identity=30.690537084399, Blast_Score=382, Evalue=1e-105,
Organism=Homo sapiens, GI44662838, Length=382, Percent_Identity=25.9162303664921, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI257796258, Length=382, Percent_Identity=25.9162303664921, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI8923708, Length=311, Percent_Identity=24.1157556270096, Blast_Score=68, Evalue=4e-11,
Organism=Escherichia coli, GI1787438, Length=441, Percent_Identity=22.2222222222222, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789272, Length=225, Percent_Identity=25.3333333333333, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32563613, Length=841, Percent_Identity=31.15338882283, Blast_Score=347, Evalue=1e-95,
Organism=Caenorhabditis elegans, GI71994045, Length=841, Percent_Identity=27.705112960761, Blast_Score=262, Evalue=6e-70,
Organism=Caenorhabditis elegans, GI71994052, Length=848, Percent_Identity=27.4764150943396, Blast_Score=259, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI17541536, Length=436, Percent_Identity=24.3119266055046, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28571104, Length=844, Percent_Identity=36.3744075829384, Blast_Score=495, Evalue=1e-140,
Organism=Drosophila melanogaster, GI20130091, Length=859, Percent_Identity=31.1990686845169, Blast_Score=408, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 88612; Mature: 88481

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPFSAPPVPSHARVVIVGGGIIGCSTAYHLARAGITDVVLLEQGQLSCGTTWHAAGLV
CCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHH
GQLRTQRSLTQLIRYSTELYASLEAETGLATGWKRCGSLSVARTAERLTQLKRTAAMARA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
YGVECELIDARAAGALWPAMRTDDLAGAAWLPGDGKANPTDLTQSLARGARQRGVRIIES
HCCEEEEECCCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEC
TRVTAVLSERTGTRRRAAGVVWRNKAGDTGTLGAEFVVNCAGQWAKGLGRLADVTVPLHA
CEEEEEEHHCCCCHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHEEEEEEEC
AEHYYIVTGRIPGTHPDLPVMRDPDGYVYFKEEVGGLVMGGFEPDAKPWGMDGIPDQFEF
CCEEEEEECCCCCCCCCCCCEECCCCCEEEHHCCCCEEEECCCCCCCCCCCCCCCCCCEE
QLLPDDWDQFEILMRNALHRVPALETAEVRQFYNGPESFTPDNHFILGEAPELANFFVGA
EECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHCC
GFNSMGIASAGGAGRALAEWIEAGEPTLDLWAVDLRRFARLHGNDAWLHDRVKETLGLHY
CCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEE
AMPWPNRELESARGVRRSPVHAQLQAAGACFGSRMGWEIVNVFAPPGQPPRIDYRFGRQN
ECCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCCC
WHDWSAAEHRACREAVALFDRSALAKLLVKGRDAESALQSRLANDVAVAPGSIVRSGILN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCC
TRGGYESDVVLARLADDRYLLLTGTTQATRDLDLLERHLEAGDRRCVALDVTGQYALFSL
CCCCCCCCEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHH
IGPHARALLQRVSRADLRDAGFAAGTCREIELGHATVHALRHAIAGAPGWDLLVPVESAV
HCHHHHHHHHHHHHCCHHHCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCEEEEECCCCC
PVHAALVHAGAALGLVQAGEYALESLRIENGQAAWGRELSPSLDPFEAGLAGLCKLAMPI
CHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
PFTGSAALAARAGLPCRRRVVALRVEGRPDVTLWGGEAILRDGAAVGLLSSAGFGHTLGL
CCCCCHHHHHHCCCCCCEEEEEEEECCCCCEEEECCHHHHHCCCCEEEHHCCCCCCCCCH
PVALGVVSCAAGAPDPTEGRYQIELAGERLAATARLPAPHDPAGLGRPA
HHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
AAPFSAPPVPSHARVVIVGGGIIGCSTAYHLARAGITDVVLLEQGQLSCGTTWHAAGLV
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHH
GQLRTQRSLTQLIRYSTELYASLEAETGLATGWKRCGSLSVARTAERLTQLKRTAAMARA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
YGVECELIDARAAGALWPAMRTDDLAGAAWLPGDGKANPTDLTQSLARGARQRGVRIIES
HCCEEEEECCCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEC
TRVTAVLSERTGTRRRAAGVVWRNKAGDTGTLGAEFVVNCAGQWAKGLGRLADVTVPLHA
CEEEEEEHHCCCCHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHEEEEEEEC
AEHYYIVTGRIPGTHPDLPVMRDPDGYVYFKEEVGGLVMGGFEPDAKPWGMDGIPDQFEF
CCEEEEEECCCCCCCCCCCCEECCCCCEEEHHCCCCEEEECCCCCCCCCCCCCCCCCCEE
QLLPDDWDQFEILMRNALHRVPALETAEVRQFYNGPESFTPDNHFILGEAPELANFFVGA
EECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHCC
GFNSMGIASAGGAGRALAEWIEAGEPTLDLWAVDLRRFARLHGNDAWLHDRVKETLGLHY
CCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEE
AMPWPNRELESARGVRRSPVHAQLQAAGACFGSRMGWEIVNVFAPPGQPPRIDYRFGRQN
ECCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCCC
WHDWSAAEHRACREAVALFDRSALAKLLVKGRDAESALQSRLANDVAVAPGSIVRSGILN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCC
TRGGYESDVVLARLADDRYLLLTGTTQATRDLDLLERHLEAGDRRCVALDVTGQYALFSL
CCCCCCCCEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHH
IGPHARALLQRVSRADLRDAGFAAGTCREIELGHATVHALRHAIAGAPGWDLLVPVESAV
HCHHHHHHHHHHHHCCHHHCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCEEEEECCCCC
PVHAALVHAGAALGLVQAGEYALESLRIENGQAAWGRELSPSLDPFEAGLAGLCKLAMPI
CHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
PFTGSAALAARAGLPCRRRVVALRVEGRPDVTLWGGEAILRDGAAVGLLSSAGFGHTLGL
CCCCCHHHHHHCCCCCCEEEEEEEECCCCCEEEECCHHHHHCCCCEEEHHCCCCCCCCCH
PVALGVVSCAAGAPDPTEGRYQIELAGERLAATARLPAPHDPAGLGRPA
HHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA