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The map label for this gene is pdxY [H]

Identifier: 238026646

GI number: 238026646

Start: 1076185

End: 1077048

Strand: Reverse

Name: pdxY [H]

Synonym: bglu_1g09980

Alternate gene names: 238026646

Gene position: 1077048-1076185 (Counterclockwise)

Preceding gene: 238026647

Following gene: 238026645

Centisome position: 27.57

GC content: 69.21

Gene sequence:

>864_bases
ATGAAGAACGTCCTCAGCATTCAGTCGCACGTGATCTACGGGCATGCGGGCAACAGCGCGGCCGTGTTCCCGATGCAGCG
CCTCGGTGTGAACGTCTGGCCGCTCAACACGGTCCAGCTCTCGAACCACATGCAGTACGGCAACTGGGCCGGCAGCGCGA
TCGACGCGGCGAAGATGGAGCAGCTGGTGGACGGCATCGCCGCGATCGGCGCGCTCAAGCGCTGCGACGCGATCCTCTCG
GGCTTCCTGGGCTCGCCCGCGCAGGCGCATGCGGCGGCCGACATCGTGCGCACCGTCAAGTCGATGAATCCCAACGCCTG
GTACTTCTGCGATCCGGCGATGGGCCAGACCGGCGGGGTGCGCCCGGAGCCAGGCGTCGAGGAATTCATCGTGTCCGAGC
TGCCGGCGCTGGCCGACGGCATGGCGCCCAATCACAGCGAACTGCAGAAGCTGGCCGGACGCCGCGTCGAAACGGTGCGC
GAAGCCGTCGACGCCTGCCGCGAGCTCATCCGGCGCGGGCCGAAGATCATCCTCGTCAAGCATCTGCACGATCGCAACAG
CCCGGCCGACCGCTTCAACATGCTGGCCGTCACCGAGCACGAGGCCTGGATCGGCCAGCGGCCGCTCTACGCGTTCCCGC
GCCATCCGGTCGGCGTCGGCGATCTGACGAGCGCCGTGTTCGTGGCGCGGCGGCTGCGCGGCGACTCGCTGCGCGCCGCC
TTCGAGCACACGCTCGCGGCGGTGCACGCCGTGGTCAAGGCGACCTACGACGCGCGCCGCTACGAACTCGAGCTCGTGGC
CGCGCAGGACGAGATCGCGCGGCCGAGCGAGTGGTTCGGCGCCTGGGTGACCGACATCGAATGA

Upstream 100 bases:

>100_bases
CCGGCCCCGACCTTCCCGGCGCGGTTCGATCAGCGCGTGTTTCCGTGTCGCGGCGAGTTCCTGTATCGTGCAGACACCGA
ACCGCGATCAGCCGCCGATC

Downstream 100 bases:

>100_bases
GCGCGGCGCGGCGAGCGGCGCACCGGCACCACATGCCCGCGCCGCTCGCTCGTTTCCCGGCCCCGCTTGCCGGCCCCGCT
TTTCGGCCCCCGCTTTTCGG

Product: pyridoxal/pyridoxine/pyridoxamine kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKNVLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTVQLSNHMQYGNWAGSAIDAAKMEQLVDGIAAIGALKRCDAILS
GFLGSPAQAHAAADIVRTVKSMNPNAWYFCDPAMGQTGGVRPEPGVEEFIVSELPALADGMAPNHSELQKLAGRRVETVR
EAVDACRELIRRGPKIILVKHLHDRNSPADRFNMLAVTEHEAWIGQRPLYAFPRHPVGVGDLTSAVFVARRLRGDSLRAA
FEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTDIE

Sequences:

>Translated_287_residues
MKNVLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTVQLSNHMQYGNWAGSAIDAAKMEQLVDGIAAIGALKRCDAILS
GFLGSPAQAHAAADIVRTVKSMNPNAWYFCDPAMGQTGGVRPEPGVEEFIVSELPALADGMAPNHSELQKLAGRRVETVR
EAVDACRELIRRGPKIILVKHLHDRNSPADRFNMLAVTEHEAWIGQRPLYAFPRHPVGVGDLTSAVFVARRLRGDSLRAA
FEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTDIE
>Mature_287_residues
MKNVLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTVQLSNHMQYGNWAGSAIDAAKMEQLVDGIAAIGALKRCDAILS
GFLGSPAQAHAAADIVRTVKSMNPNAWYFCDPAMGQTGGVRPEPGVEEFIVSELPALADGMAPNHSELQKLAGRRVETVR
EAVDACRELIRRGPKIILVKHLHDRNSPADRFNMLAVTEHEAWIGQRPLYAFPRHPVGVGDLTSAVFVARRLRGDSLRAA
FEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTDIE

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=300, Percent_Identity=28, Blast_Score=119, Evalue=3e-27,
Organism=Escherichia coli, GI1787924, Length=284, Percent_Identity=54.2253521126761, Blast_Score=290, Evalue=9e-80,
Organism=Escherichia coli, GI1788758, Length=264, Percent_Identity=26.1363636363636, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17507759, Length=259, Percent_Identity=29.7297297297297, Blast_Score=117, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17507757, Length=269, Percent_Identity=28.6245353159851, Blast_Score=111, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6324354, Length=272, Percent_Identity=31.6176470588235, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6320806, Length=275, Percent_Identity=29.8181818181818, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI45553007, Length=292, Percent_Identity=29.1095890410959, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 31417; Mature: 31417

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTVQLSNHMQYGNWAGSAIDAAKME
CCCHHEEHHEEEEEECCCCCEECCHHHHCCEECCCCEEECCCCCCCCCCCCCHHHHHHHH
QLVDGIAAIGALKRCDAILSGFLGSPAQAHAAADIVRTVKSMNPNAWYFCDPAMGQTGGV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
RPEPGVEEFIVSELPALADGMAPNHSELQKLAGRRVETVREAVDACRELIRRGPKIILVK
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
HLHDRNSPADRFNMLAVTEHEAWIGQRPLYAFPRHPVGVGDLTSAVFVARRLRGDSLRAA
ECCCCCCCHHHHEEEEEECCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHH
FEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTDIE
HHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHCCCHHHHCCHHCCCC
>Mature Secondary Structure
MKNVLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTVQLSNHMQYGNWAGSAIDAAKME
CCCHHEEHHEEEEEECCCCCEECCHHHHCCEECCCCEEECCCCCCCCCCCCCHHHHHHHH
QLVDGIAAIGALKRCDAILSGFLGSPAQAHAAADIVRTVKSMNPNAWYFCDPAMGQTGGV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
RPEPGVEEFIVSELPALADGMAPNHSELQKLAGRRVETVREAVDACRELIRRGPKIILVK
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
HLHDRNSPADRFNMLAVTEHEAWIGQRPLYAFPRHPVGVGDLTSAVFVARRLRGDSLRAA
ECCCCCCCHHHHEEEEEECCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHH
FEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTDIE
HHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHCCCHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA