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The map label for this gene is aroA [H]

Identifier: 238026534

GI number: 238026534

Start: 955782

End: 957080

Strand: Direct

Name: aroA [H]

Synonym: bglu_1g08780

Alternate gene names: 238026534

Gene position: 955782-957080 (Clockwise)

Preceding gene: 238026533

Following gene: 238026535

Centisome position: 24.47

GC content: 68.51

Gene sequence:

>1299_bases
ATGGAATTCCTCGATATCGGCCCCTACTCCCGTGTGTCGGGCACGGTGCGTCTGCCCGGCTCCAAGAGCATCTCGAACCG
CGTGCTGCTGCTCGCCGCGCTGTCCGAGGGCGTGACGACGATCACCAACCTGCTCGACTCCGACGACACGCGCGTGATGC
TGGCCGCGCTCGAAGCGCTCGGCGTGCGGCTCGAACGCCATGCCGATACCTGTGTCGTGAACGGCACGCGCGGCGCGTTT
CCGGCGAAGACGGCCGATCTGTTTCTCGGCAACGCCGGCACCGCAGTGCGTCCGCTCACGGCTGCGCTGGCCGTCAACGG
CGGCGACTACCGCGTCCACGGCGTGCCGCGCATGCACGAGCGGCCGATCGGCGACCTCGTCGACGGCCTGCGCCAGATCG
GCGCCGTGATCGACTACGAGCAGAACGAAGGGTATCCGCCGCTGCGGATCCAGGCCGGTACGATCGCCGTCGACGCACCG
ATCCGCGTGCGCGGCGACGTGTCTAGCCAGTTCCTGACCGCGCTGCTGATGACGCTGCCGCTCGTCGGCAAGAAGGGGGG
CGCGAGCGTCGTCGAGATCGACGGCGAGCTGATCTCGAAGCCCTACATCGAGATCACGATCAAGCTGATGGCGCGCTTCG
GCGTGACGGTCGAGCGTGACGGCTGGCAGCGCTTCAGCGTGCCGGCGGCGCGCTACCAGTCGCCGGGCACGATCATGGTG
GAGGGCGACGCGTCGTCCGCATCGTATTTCCTCGCGGCCGGCGCGCTCGGCGGCGGCCCGCTGCGCATCGAGGGCGTGGG
CCGCGCCAGCATCCAGGGCGACGTTGGCTTTGCCACGGCGCTCATGCAGATGGGCGCGAACGTCTCGATGGGCGACGACT
GGATCGAGGTGCGCGGCATCGGCCACGACCACGGCAAGCTCGAGCCGATCGACATGGACTTCAACCTGATCCCCGACGCG
GCGATGACGATCGCGGTGGCCGCGCTGTTCGCCGAGGGCACCAGCACGCTGCGCAACATCGCAAGCTGGCGCGTCAAGGA
GACCGACCGGATCGCGGCGATGGCCGCCGAGTTGCGCAAGCTGGGCGCGACCGTGGAGGAGGGCGCCGACTACCTCGTCG
TCACGCCGCCCGCGAAGCTCGTGCCGAATGCCGCGATCGACACCTATGACGATCACCGCATGGCGATGTGTTTCTCGCTC
GTGAGCCTCGGCGGCGTGCCGGTGCGGATCAACGATCCGAAGTGCGTCGCCAAGACTTTCCCCGATTATTTCGACCGCTT
TACCGCGCTCGCGCGCTGA

Upstream 100 bases:

>100_bases
CTCGAGGCAGTCTTCACCCGTTCGCGCGCCGCGCGCACGGCCTGGCAGGAGCGCGGCGGCAAAGCCGCCCCCGGTTCCGT
TCAGTCATAACAGGATCTTT

Downstream 100 bases:

>100_bases
TCCGTTTGTTCCGATGAAATCGACTCGACCATTCCACCCGACCCCCGTCATCACGATCGACGGCCCGACCGCGTCCGGCA
AGGGCACGGTTGCCGCGCTC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MEFLDIGPYSRVSGTVRLPGSKSISNRVLLLAALSEGVTTITNLLDSDDTRVMLAALEALGVRLERHADTCVVNGTRGAF
PAKTADLFLGNAGTAVRPLTAALAVNGGDYRVHGVPRMHERPIGDLVDGLRQIGAVIDYEQNEGYPPLRIQAGTIAVDAP
IRVRGDVSSQFLTALLMTLPLVGKKGGASVVEIDGELISKPYIEITIKLMARFGVTVERDGWQRFSVPAARYQSPGTIMV
EGDASSASYFLAAGALGGGPLRIEGVGRASIQGDVGFATALMQMGANVSMGDDWIEVRGIGHDHGKLEPIDMDFNLIPDA
AMTIAVAALFAEGTSTLRNIASWRVKETDRIAAMAAELRKLGATVEEGADYLVVTPPAKLVPNAAIDTYDDHRMAMCFSL
VSLGGVPVRINDPKCVAKTFPDYFDRFTALAR

Sequences:

>Translated_432_residues
MEFLDIGPYSRVSGTVRLPGSKSISNRVLLLAALSEGVTTITNLLDSDDTRVMLAALEALGVRLERHADTCVVNGTRGAF
PAKTADLFLGNAGTAVRPLTAALAVNGGDYRVHGVPRMHERPIGDLVDGLRQIGAVIDYEQNEGYPPLRIQAGTIAVDAP
IRVRGDVSSQFLTALLMTLPLVGKKGGASVVEIDGELISKPYIEITIKLMARFGVTVERDGWQRFSVPAARYQSPGTIMV
EGDASSASYFLAAGALGGGPLRIEGVGRASIQGDVGFATALMQMGANVSMGDDWIEVRGIGHDHGKLEPIDMDFNLIPDA
AMTIAVAALFAEGTSTLRNIASWRVKETDRIAAMAAELRKLGATVEEGADYLVVTPPAKLVPNAAIDTYDDHRMAMCFSL
VSLGGVPVRINDPKCVAKTFPDYFDRFTALAR
>Mature_432_residues
MEFLDIGPYSRVSGTVRLPGSKSISNRVLLLAALSEGVTTITNLLDSDDTRVMLAALEALGVRLERHADTCVVNGTRGAF
PAKTADLFLGNAGTAVRPLTAALAVNGGDYRVHGVPRMHERPIGDLVDGLRQIGAVIDYEQNEGYPPLRIQAGTIAVDAP
IRVRGDVSSQFLTALLMTLPLVGKKGGASVVEIDGELISKPYIEITIKLMARFGVTVERDGWQRFSVPAARYQSPGTIMV
EGDASSASYFLAAGALGGGPLRIEGVGRASIQGDVGFATALMQMGANVSMGDDWIEVRGIGHDHGKLEPIDMDFNLIPDA
AMTIAVAALFAEGTSTLRNIASWRVKETDRIAAMAAELRKLGATVEEGADYLVVTPPAKLVPNAAIDTYDDHRMAMCFSL
VSLGGVPVRINDPKCVAKTFPDYFDRFTALAR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=436, Percent_Identity=58.2568807339449, Blast_Score=461, Evalue=1e-131,
Organism=Saccharomyces cerevisiae, GI6320332, Length=448, Percent_Identity=37.0535714285714, Blast_Score=235, Evalue=1e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46013; Mature: 46013

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFLDIGPYSRVSGTVRLPGSKSISNRVLLLAALSEGVTTITNLLDSDDTRVMLAALEAL
CCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEHHCCHHHHHHHHCCCCCHHHHHHHHHH
GVRLERHADTCVVNGTRGAFPAKTADLFLGNAGTAVRPLTAALAVNGGDYRVHGVPRMHE
HHHHCCCCCEEEEECCCCCCCCCCCEEEECCCCCCHHHEEEEEEECCCCEEEECCCCHHC
RPIGDLVDGLRQIGAVIDYEQNEGYPPLRIQAGTIAVDAPIRVRGDVSSQFLTALLMTLP
CCHHHHHHHHHHHHHEEEECCCCCCCCEEEEECEEEECCCEEEECCCHHHHHHHHHHHHC
LVGKKGGASVVEIDGELISKPYIEITIKLMARFGVTVERDGWQRFSVPAARYQSPGTIMV
CCCCCCCCEEEEECHHHHCCCHHEEHHEEHHHHCCEEECCCCEEECCCHHHCCCCCEEEE
EGDASSASYFLAAGALGGGPLRIEGVGRASIQGDVGFATALMQMGANVSMGDDWIEVRGI
ECCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEC
GHDHGKLEPIDMDFNLIPDAAMTIAVAALFAEGTSTLRNIASWRVKETDRIAAMAAELRK
CCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHH
LGATVEEGADYLVVTPPAKLVPNAAIDTYDDHRMAMCFSLVSLGGVPVRINDPKCVAKTF
HCCHHHCCCCEEEECCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCHHHHHHC
PDYFDRFTALAR
HHHHHHHHHHCC
>Mature Secondary Structure
MEFLDIGPYSRVSGTVRLPGSKSISNRVLLLAALSEGVTTITNLLDSDDTRVMLAALEAL
CCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEHHCCHHHHHHHHCCCCCHHHHHHHHHH
GVRLERHADTCVVNGTRGAFPAKTADLFLGNAGTAVRPLTAALAVNGGDYRVHGVPRMHE
HHHHCCCCCEEEEECCCCCCCCCCCEEEECCCCCCHHHEEEEEEECCCCEEEECCCCHHC
RPIGDLVDGLRQIGAVIDYEQNEGYPPLRIQAGTIAVDAPIRVRGDVSSQFLTALLMTLP
CCHHHHHHHHHHHHHEEEECCCCCCCCEEEEECEEEECCCEEEECCCHHHHHHHHHHHHC
LVGKKGGASVVEIDGELISKPYIEITIKLMARFGVTVERDGWQRFSVPAARYQSPGTIMV
CCCCCCCCEEEEECHHHHCCCHHEEHHEEHHHHCCEEECCCCEEECCCHHHCCCCCEEEE
EGDASSASYFLAAGALGGGPLRIEGVGRASIQGDVGFATALMQMGANVSMGDDWIEVRGI
ECCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEC
GHDHGKLEPIDMDFNLIPDAAMTIAVAALFAEGTSTLRNIASWRVKETDRIAAMAAELRK
CCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHH
LGATVEEGADYLVVTPPAKLVPNAAIDTYDDHRMAMCFSLVSLGGVPVRINDPKCVAKTF
HCCHHHCCCCEEEECCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCHHHHHHC
PDYFDRFTALAR
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA