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The map label for this gene is rppH [H]

Identifier: 238026158

GI number: 238026158

Start: 515703

End: 516335

Strand: Reverse

Name: rppH [H]

Synonym: bglu_1g04880

Alternate gene names: 238026158

Gene position: 516335-515703 (Counterclockwise)

Preceding gene: 238026161

Following gene: 238026157

Centisome position: 13.22

GC content: 63.51

Gene sequence:

>633_bases
ATGCTGGATCGTGAAGGCTTTCGCCCGAACGTCGGCATCATCCTGCTGAACGCGCGCAATGAGGTGTTTTGGGGCAAGCG
GCTTCGTGAACATTCCTGGCAATTCCCGCAAGGGGGCATCAAGTATGGTGAGACCCCGATGCAGGCGATGTTCCGGGAAT
TGCACGAGGAAACCGGTCTGCTGCCGGAGCACGTCAAGATCATCGGTCGCACGCGCGACTGGTTGCGTTACGAGGTGCCT
GACAAGTTCATCAAGCGCGAGGTCCGCGGGCATTATCGCGGACAGAAGCAGATCTGGTTTCTGCTGCGGATGGTCGGACG
CGACTGCGACATTTGCTTGCGCGCAACCGACCACCCGGAGTTCGACGCCTGGCGCTGGAACGAGTACTGGGTGCCGCTCG
ACGCGGTGATCGAGTTCAAGCGGGATGTGTATCAGTTGGCGTTGACGGAGTTGTCGCGGTTCCTGCGCCGACCGGCGCAG
CGGCCCGACAACAAGGCGCGGGTGGCGCGGCCGACGCGCTACCCCCGCGTGATCGGCGTCCAGCCGGTCGATCCGTCGCA
GATCTGCTCGGAGGTCGAGCCGGGTGCGAGCCCGTACGACGAAGCACCGGGCAGCTTTCTGCTGCGCGACTGA

Upstream 100 bases:

>100_bases
GTGTAGCCGCCGCGCCTGCCGAGATTCTGCCCATTGCGGTGCGCGGCGCCCGTTATCTGTTTATAATCAAAGCAATTTTA
AAGGATTCGAAGGTGGTTGT

Downstream 100 bases:

>100_bases
GATCCGGCCGACCGGGTAGGAAAATCAAGCATGTCCGGGCGCGGCAGCATTTGCCGCGCCCTTTTTTCGAGGTGTGCAAT
TTGAAATCACTCGCTTTTGC

Product: RNA pyrophosphohydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MLDREGFRPNVGIILLNARNEVFWGKRLREHSWQFPQGGIKYGETPMQAMFRELHEETGLLPEHVKIIGRTRDWLRYEVP
DKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPEFDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQ
RPDNKARVARPTRYPRVIGVQPVDPSQICSEVEPGASPYDEAPGSFLLRD

Sequences:

>Translated_210_residues
MLDREGFRPNVGIILLNARNEVFWGKRLREHSWQFPQGGIKYGETPMQAMFRELHEETGLLPEHVKIIGRTRDWLRYEVP
DKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPEFDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQ
RPDNKARVARPTRYPRVIGVQPVDPSQICSEVEPGASPYDEAPGSFLLRD
>Mature_210_residues
MLDREGFRPNVGIILLNARNEVFWGKRLREHSWQFPQGGIKYGETPMQAMFRELHEETGLLPEHVKIIGRTRDWLRYEVP
DKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPEFDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQ
RPDNKARVARPTRYPRVIGVQPVDPSQICSEVEPGASPYDEAPGSFLLRD

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1789194, Length=169, Percent_Identity=44.9704142011834, Blast_Score=168, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 24890; Mature: 24890

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDREGFRPNVGIILLNARNEVFWGKRLREHSWQFPQGGIKYGETPMQAMFRELHEETGL
CCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
LPEHVKIIGRTRDWLRYEVPDKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPE
CHHHHHHHHCCHHHHEECCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCC
FDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQRPDNKARVARPTRYPRVIGV
CCCEECCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEC
QPVDPSQICSEVEPGASPYDEAPGSFLLRD
CCCCHHHHHHHCCCCCCCCCCCCCCEECCC
>Mature Secondary Structure
MLDREGFRPNVGIILLNARNEVFWGKRLREHSWQFPQGGIKYGETPMQAMFRELHEETGL
CCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
LPEHVKIIGRTRDWLRYEVPDKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPE
CHHHHHHHHCCHHHHEECCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCC
FDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQRPDNKARVARPTRYPRVIGV
CCCEECCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEC
QPVDPSQICSEVEPGASPYDEAPGSFLLRD
CCCCHHHHHHHCCCCCCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA