Click here to switch to the map view.

The map label for this gene is hpt [H]

Identifier: 238026161

GI number: 238026161

Start: 519081

End: 519632

Strand: Reverse

Name: hpt [H]

Synonym: bglu_1g04910

Alternate gene names: 238026161

Gene position: 519632-519081 (Counterclockwise)

Preceding gene: 238026162

Following gene: 238026158

Centisome position: 13.3

GC content: 65.58

Gene sequence:

>552_bases
ATGAATCGCGAAGAAGCCCTCCATATATTCCAGCATTCCGAACAGATCGTCTCCGCCGACGAGGTCAGCGCCTCGATCGG
CCGGATGGCTGCGGCGATCCGCGACGAAATCGGCGAGGCGTTTCCGCTCGTGCTGTCGGTGATGGGCGGCGCCGCCGTGT
TCACCGGCATGCTGCTGCCGCACCTCGATTTCCCGCTCGAGTTCGACTACATCCATCTGACGCGCTACCGCAACACCACC
CAGGGCAGCCCCGAGATGCACTGGCGCGTGGCCCCGCGCGAGTCGGTCAAGGACCGCATCGTGATCGTGCTCGACGATAT
CCTCGACGAAGGCGAGACGATGGCCGCGATCCGTGACCGGATCCTCGAGATGGGCGCCAAGCGCTTCCTGTCGGCCGTGC
TCTGCGAGAAGACGCTCACCAAGCCCAAGCCGCTGCGCCCCGATTTCTGCGGATTCTCGGTGCCGGATCGCTACGTGTTC
GGCTGCGGGATGGACGCGAAGGGCTACTGGCGCAACCTGCCCACCATCCGCGCGCTGACGGCCGAGGCCTGA

Upstream 100 bases:

>100_bases
TCCTAATGGCGCATCGCCCGCTGCCCCGCATTGTCGGGGCGCCCCGCCGCGAGTCCATTCACCGCGGCTTTCGACTGACC
CGGATCGCACGCCACAGCTC

Downstream 100 bases:

>100_bases
GCTTCCGCCAGCCTGGCACCCTCGGGCGTGCCCGGCGGCGCCCAATAGCAAAACGGCTCGCGTAGCACTACGCGAGCCGT
TTTTTTCTTGCGCCGGCAGG

Product: hypoxanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: HGPRT; HGPRTase [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MNREEALHIFQHSEQIVSADEVSASIGRMAAAIRDEIGEAFPLVLSVMGGAAVFTGMLLPHLDFPLEFDYIHLTRYRNTT
QGSPEMHWRVAPRESVKDRIVIVLDDILDEGETMAAIRDRILEMGAKRFLSAVLCEKTLTKPKPLRPDFCGFSVPDRYVF
GCGMDAKGYWRNLPTIRALTAEA

Sequences:

>Translated_183_residues
MNREEALHIFQHSEQIVSADEVSASIGRMAAAIRDEIGEAFPLVLSVMGGAAVFTGMLLPHLDFPLEFDYIHLTRYRNTT
QGSPEMHWRVAPRESVKDRIVIVLDDILDEGETMAAIRDRILEMGAKRFLSAVLCEKTLTKPKPLRPDFCGFSVPDRYVF
GCGMDAKGYWRNLPTIRALTAEA
>Mature_183_residues
MNREEALHIFQHSEQIVSADEVSASIGRMAAAIRDEIGEAFPLVLSVMGGAAVFTGMLLPHLDFPLEFDYIHLTRYRNTT
QGSPEMHWRVAPRESVKDRIVIVLDDILDEGETMAAIRDRILEMGAKRFLSAVLCEKTLTKPKPLRPDFCGFSVPDRYVF
GCGMDAKGYWRNLPTIRALTAEA

Specific function: This Enzyme Acts Exclusively On Hypoxanthine; It Does Not Act On Guanine (By Similarity). [C]

COG id: COG0634

COG function: function code F; Hypoxanthine-guanine phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17510817, Length=162, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005904
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.8 [H]

Molecular weight: Translated: 20540; Mature: 20540

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNREEALHIFQHSEQIVSADEVSASIGRMAAAIRDEIGEAFPLVLSVMGGAAVFTGMLLP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLDFPLEFDYIHLTRYRNTTQGSPEMHWRVAPRESVKDRIVIVLDDILDEGETMAAIRDR
CCCCCCCCCEEEEEECCCCCCCCCCEEEEECCHHCCCCEEEEEEHHHHCCCHHHHHHHHH
ILEMGAKRFLSAVLCEKTLTKPKPLRPDFCGFSVPDRYVFGCGMDAKGYWRNLPTIRALT
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHCCCHHHHCC
AEA
CCC
>Mature Secondary Structure
MNREEALHIFQHSEQIVSADEVSASIGRMAAAIRDEIGEAFPLVLSVMGGAAVFTGMLLP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLDFPLEFDYIHLTRYRNTTQGSPEMHWRVAPRESVKDRIVIVLDDILDEGETMAAIRDR
CCCCCCCCCEEEEEECCCCCCCCCCEEEEECCHHCCCCEEEEEEHHHHCCCHHHHHHHHH
ILEMGAKRFLSAVLCEKTLTKPKPLRPDFCGFSVPDRYVFGCGMDAKGYWRNLPTIRALT
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHCCCHHHHCC
AEA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]