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The map label for this gene is hisC [H]

Identifier: 238026006

GI number: 238026006

Start: 351941

End: 353011

Strand: Direct

Name: hisC [H]

Synonym: bglu_1g03320

Alternate gene names: 238026006

Gene position: 351941-353011 (Clockwise)

Preceding gene: 238026005

Following gene: 238026007

Centisome position: 9.01

GC content: 70.03

Gene sequence:

>1071_bases
ATGACGACGCCACAAGACATCATCCGCCCCGACGTGCTCGCGATGACGAGCTACCCGGTGCCGGACGCGGCCGGGCTCGT
GAAGCTCGACGCGATGGAAAGCCCGTATGGGCTGCCCGCGCCGCTCGCGGCCGGGCTCGGTGAGCGGCTCGCGCAGCTCG
CGCTGAACCGCTATCCGCCGCCGCGTCCCGCCGCGCTGATCGCCAAGCTGCGCGCCGCGATGGGGATTCCCGACGGCTGC
GAGGTGCTGCTCGGCAACGGCTCGGACGAGATCATCGGAATGCTGGCGGTGGCCTGCGCGCGGCCCGGTGCGAAGGTGCT
GATGCCGGTGCCCGGCTTCGTGATGGTCGAGCAGTACGCGCGCCTCGCGCAGATGGCGTTCGTCGGCGTGCCGTTGCGCG
CGGATATGTCCCTCGACGTCGACGCGCTGCTCGCGGCGATCGCCGAACACCGGCCGGCGCTGATCCACCTGGCCTATCCG
AACAATCCCACCGGCACGCTCTATGCCGAGGCCGACATCGAGCGCGTGATCGCCGCCGCGCGTACCAGCCTGGTGGTGAT
CGACGAGGCCTACCAGCCGTTCGCCGAGCGCAGCTGGCTCGCGCGCGTCCCCGAATTCGACAACGTGGTGGTGATGCGCA
CCGTCTCGAAGCTCGGCCTGGCCGGGGTGCGCTTCGGCTATCTGGTCGGCGCGCCGGCCTGGCTGGCCGAAATCGACAAG
GTGCGCCCGCCCTACAACGTCAACCTGCTGACCCAGGGCTGCATCGACTACCTGCTCGATCACCTCGACGTGCTCGACGC
CCAGGCCGCGCAACTGCGCGCCGAGCGCGGCCGGCTCGCCGCGGCGGTGGCCGCGCTGCCCGGCGCGACGGTATTCCCGA
GCGCCGGCAATTTCCTGCTGGTGCGCGTGCCCGACGCCTGCGCCCTGTTCGACGCGCTGCTCATCGAGCGGGTGTTGATC
AAAAACGTGAGTAAAATGCATCCGTTGCTCGCGAACTGCGTGCGGCTGACGGTCGGTTCTCCTGAGGAGAACGCCGCGCT
GCTCGCCGCGTTGCGACTGGTGCTGCGCTAG

Upstream 100 bases:

>100_bases
CGACGGAGCCGGCCGCGGCCGGGCCGGCGGCATCGAGACCCGCGGCCCGGACGATCCGGGCCGCCGACACGGGCGGCGCG
AGGCACGCCGCGGACCCATC

Downstream 100 bases:

>100_bases
CGCGGGCCGCGCGCCGCCGGGCGGCCGCCGCGGCCTCGCGCGTCCCCCATTACCCAGTCATTTCAAGGAATCACCATGCG
CGTGGCGGAAGTCGTTCGCG

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTTPQDIIRPDVLAMTSYPVPDAAGLVKLDAMESPYGLPAPLAAGLGERLAQLALNRYPPPRPAALIAKLRAAMGIPDGC
EVLLGNGSDEIIGMLAVACARPGAKVLMPVPGFVMVEQYARLAQMAFVGVPLRADMSLDVDALLAAIAEHRPALIHLAYP
NNPTGTLYAEADIERVIAAARTSLVVIDEAYQPFAERSWLARVPEFDNVVVMRTVSKLGLAGVRFGYLVGAPAWLAEIDK
VRPPYNVNLLTQGCIDYLLDHLDVLDAQAAQLRAERGRLAAAVAALPGATVFPSAGNFLLVRVPDACALFDALLIERVLI
KNVSKMHPLLANCVRLTVGSPEENAALLAALRLVLR

Sequences:

>Translated_356_residues
MTTPQDIIRPDVLAMTSYPVPDAAGLVKLDAMESPYGLPAPLAAGLGERLAQLALNRYPPPRPAALIAKLRAAMGIPDGC
EVLLGNGSDEIIGMLAVACARPGAKVLMPVPGFVMVEQYARLAQMAFVGVPLRADMSLDVDALLAAIAEHRPALIHLAYP
NNPTGTLYAEADIERVIAAARTSLVVIDEAYQPFAERSWLARVPEFDNVVVMRTVSKLGLAGVRFGYLVGAPAWLAEIDK
VRPPYNVNLLTQGCIDYLLDHLDVLDAQAAQLRAERGRLAAAVAALPGATVFPSAGNFLLVRVPDACALFDALLIERVLI
KNVSKMHPLLANCVRLTVGSPEENAALLAALRLVLR
>Mature_355_residues
TTPQDIIRPDVLAMTSYPVPDAAGLVKLDAMESPYGLPAPLAAGLGERLAQLALNRYPPPRPAALIAKLRAAMGIPDGCE
VLLGNGSDEIIGMLAVACARPGAKVLMPVPGFVMVEQYARLAQMAFVGVPLRADMSLDVDALLAAIAEHRPALIHLAYPN
NPTGTLYAEADIERVIAAARTSLVVIDEAYQPFAERSWLARVPEFDNVVVMRTVSKLGLAGVRFGYLVGAPAWLAEIDKV
RPPYNVNLLTQGCIDYLLDHLDVLDAQAAQLRAERGRLAAAVAALPGATVFPSAGNFLLVRVPDACALFDALLIERVLIK
NVSKMHPLLANCVRLTVGSPEENAALLAALRLVLR

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=372, Percent_Identity=29.3010752688172, Blast_Score=117, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6322075, Length=385, Percent_Identity=29.0909090909091, Blast_Score=111, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 37985; Mature: 37854

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPQDIIRPDVLAMTSYPVPDAAGLVKLDAMESPYGLPAPLAAGLGERLAQLALNRYPP
CCCCHHHHCCCHHEEECCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
PRPAALIAKLRAAMGIPDGCEVLLGNGSDEIIGMLAVACARPGAKVLMPVPGFVMVEQYA
CCHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHH
RLAQMAFVGVPLRADMSLDVDALLAAIAEHRPALIHLAYPNNPTGTLYAEADIERVIAAA
HHHHHHHHCCCEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEHHHHHHHHHHH
RTSLVVIDEAYQPFAERSWLARVPEFDNVVVMRTVSKLGLAGVRFGYLVGAPAWLAEIDK
HHEEEEEEHHHCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VRPPYNVNLLTQGCIDYLLDHLDVLDAQAAQLRAERGRLAAAVAALPGATVFPSAGNFLL
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEE
VRVPDACALFDALLIERVLIKNVSKMHPLLANCVRLTVGSPEENAALLAALRLVLR
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
>Mature Secondary Structure 
TTPQDIIRPDVLAMTSYPVPDAAGLVKLDAMESPYGLPAPLAAGLGERLAQLALNRYPP
CCCHHHHCCCHHEEECCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
PRPAALIAKLRAAMGIPDGCEVLLGNGSDEIIGMLAVACARPGAKVLMPVPGFVMVEQYA
CCHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHH
RLAQMAFVGVPLRADMSLDVDALLAAIAEHRPALIHLAYPNNPTGTLYAEADIERVIAAA
HHHHHHHHCCCEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEHHHHHHHHHHH
RTSLVVIDEAYQPFAERSWLARVPEFDNVVVMRTVSKLGLAGVRFGYLVGAPAWLAEIDK
HHEEEEEEHHHCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VRPPYNVNLLTQGCIDYLLDHLDVLDAQAAQLRAERGRLAAAVAALPGATVFPSAGNFLL
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEE
VRVPDACALFDALLIERVLIKNVSKMHPLLANCVRLTVGSPEENAALLAALRLVLR
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12754231 [H]