Click here to switch to the map view.

The map label for this gene is tcp [H]

Identifier: 238024370

GI number: 238024370

Start: 1180533

End: 1182254

Strand: Direct

Name: tcp [H]

Synonym: bglu_2g09630

Alternate gene names: 238024370

Gene position: 1180533-1182254 (Clockwise)

Preceding gene: 238024366

Following gene: 238024375

Centisome position: 41.75

GC content: 66.67

Gene sequence:

>1722_bases
ATGAAAAACGTGACTGTATCCACCCGCCTGATCGCCGGGTTCGGGTTGTTGACCGCCTTGTTGCTGGCAGTAGCGGCAAT
TGGCTTTTATGGCCTGTCGCAATTGAATGGGAGGCTGGACGATATCGCACGCGTGAACAACGCCGAAACCAAGCTGGCTA
ACCAGTTGCGCACCTCGATACAGGATCGGGCGATCGCCGTGCGAAATTTGGCGCTGCTCAGCGACGCGCAGGACATGGCC
AAGGAGGCCGAGCGCATCAGCAAGCAGGAGCAGATCTATGCCGACGCGTACCAGAAGCTGTCGCAGCTGTTTACCGACGA
ACCCGGTACGACGGAGCGCGAGAAAGCGCTCCTCGCTCAGATCAGGCGAGACGAGGCGGCGGCACTGCCGCCGCTGCGCA
AGGCGGCCCAACTGAGCCTGGCGAACGACAGGGAGGGCGCTACCCGCGAGTTGCTGCAGAACGCCAGAACGCCCCAACGA
ACCTGGCTGGCACGCGCGGTCGAGCTGGCTGATTTCGAGGACCAGCTCAACGACCAGGCGCAACGGGACGCCGTGAGCCT
GTACTCGAGCGTGCGGGTACTGATCGCGGCCATCGTCGCGGCCTCGCTGCTGGTGGCGGCCGTGGCCGCGGTCCTCATTA
CGCGCAGCATCCTGAGGCAGCTTGGCGGCGAACCCGGCCTCGCGCAGTCGGTGGCGGCGGAGATCGCCAATGGCAACCTG
ATGGTGGACCTGCATCTGAAGCCCGGCGATTCGACCAGCCTGATGGCCTCGCTGGAAGCGATGCGCGCCAGGCTGACCTC
GATCGTGCACGGCATCAAGACCTCGGCCGAATCCATCTCGGTTGCCGCCAACCAGGTTGCGCAGGGCAATGTGGATCTCT
CCCAGCGCACCGAGGAACAGGCGGCATCGCTCGAAGAGACGGCGGCCAGCATGGAGGAACTGACCTCGACGGTGAAGCAC
AACACCGACAATGCCCGGCAGGGCAGCACGCTCGCGGTCACGGCTTCGCAGACCGCTACGTCGGGCGGTGACGTGGTCCG
GCAGGTGATGGGCACCATGGATGACATCACGTCGAGCTCGCGCAAGGTTGCCGAGATCATTTCCGTGATCGAGGGCATTG
CCTTCCAGACCAATATCCTGGCGCTCAACGCGGCGGTCGAGGCGGCGCGCGCAGGCGAGCAGGGGCGCGGCTTCGCGGTG
GTCGCCGGGGAGGTACGCACGCTGGCGCAGCGCAGCGCGGTGGCGGCCAAGGAAATCAAGGAACTGATCGAGACGTCGGT
ATCGCATGTGGCAGCGGGCTCGCAATTGGTGGGCGATGCCGGCACGACCATGGACGAGATCGTGCGCTCGGTGAAGCGGG
TCAGCGACATCATGGGCGAGATCGCGTCGGCGTCGGCGGAGCAGAGCACGGGAATCGAGCAGGTCAACGTGGCGGTGGCG
CAGATGGACGAGGTCACCCAGCAGAACGCGGCGCTGGTGGAGCAGGCCACGGCCGCGGCGCAGTCGATGGCGGATCAGGC
GGAAAATCTGCGGGCCACGGTGTCGATCTTCCGGGTCGATGCGAGGGTGCAGACGGAGCCCGCCGCCGCCGTGAAGCGGC
AGGTGAGCGTCGCGCCGAAGCAGGCCAAGCGCCGTCCCGAACCGGCACGGCTGCCGGCACGGGTGGCCGCGCCGGCGGCC
GCTGCGGCCGGGGCGGGAAGCGGCGAGTGGGCCACGTTCTGA

Upstream 100 bases:

>100_bases
TTTCAATATATTGATCAGGATAAGGTTTTCCCGACCTTCAGTAGTTTGTATGGATGTCGTAAACAATCTGGAAGAGTGTT
CAACATGGTCGGGAGCCGCA

Downstream 100 bases:

>100_bases
CGCGCAGGCAGGCGGCCGTTCGGCCTGACCGGCAGCGGCGCTTGCGCATGCGCAGGCACGAGGTGATGCCGTGGCGGCGC
CTGCCGCCGATCGGCTTCTG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MKNVTVSTRLIAGFGLLTALLLAVAAIGFYGLSQLNGRLDDIARVNNAETKLANQLRTSIQDRAIAVRNLALLSDAQDMA
KEAERISKQEQIYADAYQKLSQLFTDEPGTTEREKALLAQIRRDEAAALPPLRKAAQLSLANDREGATRELLQNARTPQR
TWLARAVELADFEDQLNDQAQRDAVSLYSSVRVLIAAIVAASLLVAAVAAVLITRSILRQLGGEPGLAQSVAAEIANGNL
MVDLHLKPGDSTSLMASLEAMRARLTSIVHGIKTSAESISVAANQVAQGNVDLSQRTEEQAASLEETAASMEELTSTVKH
NTDNARQGSTLAVTASQTATSGGDVVRQVMGTMDDITSSSRKVAEIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAV
VAGEVRTLAQRSAVAAKEIKELIETSVSHVAAGSQLVGDAGTTMDEIVRSVKRVSDIMGEIASASAEQSTGIEQVNVAVA
QMDEVTQQNAALVEQATAAAQSMADQAENLRATVSIFRVDARVQTEPAAAVKRQVSVAPKQAKRRPEPARLPARVAAPAA
AAAGAGSGEWATF

Sequences:

>Translated_573_residues
MKNVTVSTRLIAGFGLLTALLLAVAAIGFYGLSQLNGRLDDIARVNNAETKLANQLRTSIQDRAIAVRNLALLSDAQDMA
KEAERISKQEQIYADAYQKLSQLFTDEPGTTEREKALLAQIRRDEAAALPPLRKAAQLSLANDREGATRELLQNARTPQR
TWLARAVELADFEDQLNDQAQRDAVSLYSSVRVLIAAIVAASLLVAAVAAVLITRSILRQLGGEPGLAQSVAAEIANGNL
MVDLHLKPGDSTSLMASLEAMRARLTSIVHGIKTSAESISVAANQVAQGNVDLSQRTEEQAASLEETAASMEELTSTVKH
NTDNARQGSTLAVTASQTATSGGDVVRQVMGTMDDITSSSRKVAEIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAV
VAGEVRTLAQRSAVAAKEIKELIETSVSHVAAGSQLVGDAGTTMDEIVRSVKRVSDIMGEIASASAEQSTGIEQVNVAVA
QMDEVTQQNAALVEQATAAAQSMADQAENLRATVSIFRVDARVQTEPAAAVKRQVSVAPKQAKRRPEPARLPARVAAPAA
AAAGAGSGEWATF
>Mature_573_residues
MKNVTVSTRLIAGFGLLTALLLAVAAIGFYGLSQLNGRLDDIARVNNAETKLANQLRTSIQDRAIAVRNLALLSDAQDMA
KEAERISKQEQIYADAYQKLSQLFTDEPGTTEREKALLAQIRRDEAAALPPLRKAAQLSLANDREGATRELLQNARTPQR
TWLARAVELADFEDQLNDQAQRDAVSLYSSVRVLIAAIVAASLLVAAVAAVLITRSILRQLGGEPGLAQSVAAEIANGNL
MVDLHLKPGDSTSLMASLEAMRARLTSIVHGIKTSAESISVAANQVAQGNVDLSQRTEEQAASLEETAASMEELTSTVKH
NTDNARQGSTLAVTASQTATSGGDVVRQVMGTMDDITSSSRKVAEIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAV
VAGEVRTLAQRSAVAAKEIKELIETSVSHVAAGSQLVGDAGTTMDEIVRSVKRVSDIMGEIASASAEQSTGIEQVNVAVA
QMDEVTQQNAALVEQATAAAQSMADQAENLRATVSIFRVDARVQTEPAAAVKRQVSVAPKQAKRRPEPARLPARVAAPAA
AAAGAGSGEWATF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=369, Percent_Identity=53.3875338753388, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1788194, Length=564, Percent_Identity=40.7801418439716, Blast_Score=300, Evalue=2e-82,
Organism=Escherichia coli, GI1788195, Length=315, Percent_Identity=57.7777777777778, Blast_Score=295, Evalue=6e-81,
Organism=Escherichia coli, GI1787690, Length=331, Percent_Identity=51.963746223565, Blast_Score=268, Evalue=6e-73,
Organism=Escherichia coli, GI1789453, Length=251, Percent_Identity=41.0358565737052, Blast_Score=191, Evalue=8e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 60384; Mature: 60384

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVTVSTRLIAGFGLLTALLLAVAAIGFYGLSQLNGRLDDIARVNNAETKLANQLRTSI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHH
QDRAIAVRNLALLSDAQDMAKEAERISKQEQIYADAYQKLSQLFTDEPGTTEREKALLAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IRRDEAAALPPLRKAAQLSLANDREGATRELLQNARTPQRTWLARAVELADFEDQLNDQA
HHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
QRDAVSLYSSVRVLIAAIVAASLLVAAVAAVLITRSILRQLGGEPGLAQSVAAEIANGNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCE
MVDLHLKPGDSTSLMASLEAMRARLTSIVHGIKTSAESISVAANQVAQGNVDLSQRTEEQ
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AASLEETAASMEELTSTVKHNTDNARQGSTLAVTASQTATSGGDVVRQVMGTMDDITSSS
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCH
RKVAEIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLAQRSAVAAKEIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
ELIETSVSHVAAGSQLVGDAGTTMDEIVRSVKRVSDIMGEIASASAEQSTGIEQVNVAVA
HHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHH
QMDEVTQQNAALVEQATAAAQSMADQAENLRATVSIFRVDARVQTEPAAAVKRQVSVAPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHCCCHHHHHHHHHHCCCH
QAKRRPEPARLPARVAAPAAAAAGAGSGEWATF
HHHCCCCCCCCCHHHHCCHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKNVTVSTRLIAGFGLLTALLLAVAAIGFYGLSQLNGRLDDIARVNNAETKLANQLRTSI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHH
QDRAIAVRNLALLSDAQDMAKEAERISKQEQIYADAYQKLSQLFTDEPGTTEREKALLAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IRRDEAAALPPLRKAAQLSLANDREGATRELLQNARTPQRTWLARAVELADFEDQLNDQA
HHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
QRDAVSLYSSVRVLIAAIVAASLLVAAVAAVLITRSILRQLGGEPGLAQSVAAEIANGNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCE
MVDLHLKPGDSTSLMASLEAMRARLTSIVHGIKTSAESISVAANQVAQGNVDLSQRTEEQ
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AASLEETAASMEELTSTVKHNTDNARQGSTLAVTASQTATSGGDVVRQVMGTMDDITSSS
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCH
RKVAEIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLAQRSAVAAKEIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
ELIETSVSHVAAGSQLVGDAGTTMDEIVRSVKRVSDIMGEIASASAEQSTGIEQVNVAVA
HHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHH
QMDEVTQQNAALVEQATAAAQSMADQAENLRATVSIFRVDARVQTEPAAAVKRQVSVAPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHCCCHHHHHHHHHHCCCH
QAKRRPEPARLPARVAAPAAAAAGAGSGEWATF
HHHCCCCCCCCCHHHHCCHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]