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The map label for this gene is fdoG [H]

Identifier: 238024280

GI number: 238024280

Start: 1047875

End: 1048465

Strand: Direct

Name: fdoG [H]

Synonym: bglu_2g08630

Alternate gene names: 238024280

Gene position: 1047875-1048465 (Clockwise)

Preceding gene: 238024279

Following gene: 238024281

Centisome position: 37.06

GC content: 65.82

Gene sequence:

>591_bases
ATGCTCCACCTGTCCCGGCGCCAGTTCTTGAAGGTGACCGCCTCCACGCTCGCCGGCTCGAGTCTCGCCCTGCTGGGATT
CTCGCCCGCCGACGCGCTCGCGGAGGTTCGCCAATACAAGCTGGCGCGCAGCGTCGAAACCCGCAACACCTGCCCGTACT
GTTCGGTGGGCTGCGGCATCCTGATGTACTCCCTCGGTGACGGCGCGAAGAACGCCAAGTCGAGCATCATCCACATCGAA
GGCGATCCCGATCATCCGGTGAACCGCGGCACGCTGTGCCCGAAGGGCGCGAGCCTGATCGACTTCATCCACAGCCCGAG
CCGGCTCACGCAGCCCGAATACCGCGCGCCCGGCTCTGACAAGTGGGAGCCGATCTCGTGGGAGGCGGCGCTCGACCGCA
TCGCGAAGCTGATGAAGGAAGACCGCGACGCCAACTTCGTCGAGACCACGCCGGACGGCCAGAAGGTCAACCGCTGGCTG
ACCACCGGCATGCTGGCCGCGTCGGCGGGCAGCAACGAAGTGGGCTATCTGACCCACAAGACGATTCGCAGTCTCGGGAT
GCTCGCCTTCGACAACCAGGCACGTGTCTGA

Upstream 100 bases:

>100_bases
GTTTCCTATAAACGAAATGAGACGGAACGCGTAAAATCGCCTCGCGACTCAGTGTCATATGAAACACCTACGTCCCCCCT
ACCTCACCGCCGAGACCACC

Downstream 100 bases:

>100_bases
CACGGCCCGACGGTGGCAGGTCTTGCCCCGACGTTTGGCCGCGGCGCGATGACGAACCATTGGGTCGACATCAAGAACGC
AGACATTATCCTGGTGATGG

Product: formate dehydrogenase major subunit

Products: NA

Alternate protein names: Aerobic formate dehydrogenase major subunit; FDH-Z subunit alpha; Formate dehydrogenase-O subunit alpha [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MLHLSRRQFLKVTASTLAGSSLALLGFSPADALAEVRQYKLARSVETRNTCPYCSVGCGILMYSLGDGAKNAKSSIIHIE
GDPDHPVNRGTLCPKGASLIDFIHSPSRLTQPEYRAPGSDKWEPISWEAALDRIAKLMKEDRDANFVETTPDGQKVNRWL
TTGMLAASAGSNEVGYLTHKTIRSLGMLAFDNQARV

Sequences:

>Translated_196_residues
MLHLSRRQFLKVTASTLAGSSLALLGFSPADALAEVRQYKLARSVETRNTCPYCSVGCGILMYSLGDGAKNAKSSIIHIE
GDPDHPVNRGTLCPKGASLIDFIHSPSRLTQPEYRAPGSDKWEPISWEAALDRIAKLMKEDRDANFVETTPDGQKVNRWL
TTGMLAASAGSNEVGYLTHKTIRSLGMLAFDNQARV
>Mature_196_residues
MLHLSRRQFLKVTASTLAGSSLALLGFSPADALAEVRQYKLARSVETRNTCPYCSVGCGILMYSLGDGAKNAKSSIIHIE
GDPDHPVNRGTLCPKGASLIDFIHSPSRLTQPEYRAPGSDKWEPISWEAALDRIAKLMKEDRDANFVETTPDGQKVNRWL
TTGMLAASAGSNEVGYLTHKTIRSLGMLAFDNQARV

Specific function: Allows to use formate as major electron donor during aerobic respiration. Subunit alpha possibly forms the active site [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868720, Length=195, Percent_Identity=73.3333333333333, Blast_Score=308, Evalue=2e-85,
Organism=Escherichia coli, GI3868719, Length=195, Percent_Identity=67.6923076923077, Blast_Score=286, Evalue=4e-79,
Organism=Escherichia coli, GI1788534, Length=188, Percent_Identity=28.7234042553192, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006443
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 21379; Mature: 21379

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS00551 MOLYBDOPTERIN_PROK_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHLSRRQFLKVTASTLAGSSLALLGFSPADALAEVRQYKLARSVETRNTCPYCSVGCGI
CCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LMYSLGDGAKNAKSSIIHIEGDPDHPVNRGTLCPKGASLIDFIHSPSRLTQPEYRAPGSD
HHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCC
KWEPISWEAALDRIAKLMKEDRDANFVETTPDGQKVNRWLTTGMLAASAGSNEVGYLTHK
CCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHH
TIRSLGMLAFDNQARV
HHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLHLSRRQFLKVTASTLAGSSLALLGFSPADALAEVRQYKLARSVETRNTCPYCSVGCGI
CCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LMYSLGDGAKNAKSSIIHIEGDPDHPVNRGTLCPKGASLIDFIHSPSRLTQPEYRAPGSD
HHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCC
KWEPISWEAALDRIAKLMKEDRDANFVETTPDGQKVNRWLTTGMLAASAGSNEVGYLTHK
CCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHH
TIRSLGMLAFDNQARV
HHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503; 8522521 [H]