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The map label for this gene is ltaE [H]

Identifier: 238024249

GI number: 238024249

Start: 1009457

End: 1010554

Strand: Reverse

Name: ltaE [H]

Synonym: bglu_2g08310

Alternate gene names: 238024249

Gene position: 1010554-1009457 (Counterclockwise)

Preceding gene: 238024268

Following gene: 238024239

Centisome position: 35.74

GC content: 73.95

Gene sequence:

>1098_bases
ATGGAACACGCCGCCTCCCCCGCCGCTCCGAACCGGGCCGACGCGCCGCTCGACTTCAGCAGCGACAACGCCGCCGGTGC
CTCGCCGGCCGTGCTCGACGCGCTGGTCGCCTGCGCCAGCGGCCGCGCGCCGGCCTACGGCGCCGACCCGTGGACGGCCA
GCGTCGAGCGGCGCCTGGCCGAATTGTTCGAGCACGAGGTGGCGGTCTCGATCGTGCCGACCGGCACCGCCGCGAACTCG
CTCGCGCTGGCCGCGCTGACGCCGCCCTGGGGCAGCGTGCTCTGCCATCCCGACAGCCATATCAACAACGACGAATGCGG
CGCGCCCGCGTTCTTCGCCGGCGGCGCGAAGCTCGTCACGGTGGCGGGGCCGGACGCCAGGATCGATCCGGCGCGGCTCG
CGGCGGCCGCCCGCGCCAAGCGCGGCGACGTCCACACCACGCAGCCGTCGGCCGTCAGCATCACGCAGGCCACCGAGGTG
GGCAGCGTCTACACGCTCGACGAAATCGGCGCGATCGGCGAGATCTGCCGCGCCGAATCGCTGTCGCTGCACATGGACGG
GGCGCGTTTCGCCAACGCGCTGGCCGCGCTGGGCTGCACGCCGGCCGAGATGACCTGGCGCGCCGGCGTGGACGCGCTCT
CGTTCGGCGCGACCAAGAACGGCGTGCCGGGCGCGGAGGCCGTGGTGCTGTTCGATACGCGCCGTGCGGCCGAACTCGCG
TTTCGCCGCAAGCGCGCCGGCCATCTGAGCTCGAAGATGCGTTTCCTGTCCGCGCCGCTCGACGCGTATCTGGCCGACGC
GCTGTGGCTGCGCAACGCGCGCCATGCCAACGCGATGGCCAAGCGCCTCGCCGACGGGCTGCAGGCGCTGCCGGGCGTCG
CGCTGGTGGGCGGCAACGCCGCCAATATTCTGTTCTGCCGACTGCCGCAGGCGCTGACCGCGGGGCTGCTGGCGGCCGGC
GTGCGCTTCTATCACGACCGCTGGGCGCCGGGCGTGGTGCGCTTCGTCACCTCGTTCGCGACCACCGAGGACGAGGTCGA
CCGGCTGCTCGCGCTCGCACGCGGGCTGAACCCGGCCGACCAGGCGCCGGCTGCCTGA

Upstream 100 bases:

>100_bases
CCGCCGCTCAAGGGGGCGGGCCATTCAATTTTTTACAATCGAGGCGGCCCGCGCCGCGTTAGGGTCGCGGTCAACGCCTT
CTTCTTCGACAGGATTCACG

Downstream 100 bases:

>100_bases
GCGGCGCCGGCCACCACCCGGGGAACGCGTGAACAGCGCACCACGGTTGCCCCCGGATGGCGTGTCAATAGCGTATCAAT
AGCGCGACGGTGCGCAGCCG

Product: phenylserine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MEHAASPAAPNRADAPLDFSSDNAAGASPAVLDALVACASGRAPAYGADPWTASVERRLAELFEHEVAVSIVPTGTAANS
LALAALTPPWGSVLCHPDSHINNDECGAPAFFAGGAKLVTVAGPDARIDPARLAAAARAKRGDVHTTQPSAVSITQATEV
GSVYTLDEIGAIGEICRAESLSLHMDGARFANALAALGCTPAEMTWRAGVDALSFGATKNGVPGAEAVVLFDTRRAAELA
FRRKRAGHLSSKMRFLSAPLDAYLADALWLRNARHANAMAKRLADGLQALPGVALVGGNAANILFCRLPQALTAGLLAAG
VRFYHDRWAPGVVRFVTSFATTEDEVDRLLALARGLNPADQAPAA

Sequences:

>Translated_365_residues
MEHAASPAAPNRADAPLDFSSDNAAGASPAVLDALVACASGRAPAYGADPWTASVERRLAELFEHEVAVSIVPTGTAANS
LALAALTPPWGSVLCHPDSHINNDECGAPAFFAGGAKLVTVAGPDARIDPARLAAAARAKRGDVHTTQPSAVSITQATEV
GSVYTLDEIGAIGEICRAESLSLHMDGARFANALAALGCTPAEMTWRAGVDALSFGATKNGVPGAEAVVLFDTRRAAELA
FRRKRAGHLSSKMRFLSAPLDAYLADALWLRNARHANAMAKRLADGLQALPGVALVGGNAANILFCRLPQALTAGLLAAG
VRFYHDRWAPGVVRFVTSFATTEDEVDRLLALARGLNPADQAPAA
>Mature_365_residues
MEHAASPAAPNRADAPLDFSSDNAAGASPAVLDALVACASGRAPAYGADPWTASVERRLAELFEHEVAVSIVPTGTAANS
LALAALTPPWGSVLCHPDSHINNDECGAPAFFAGGAKLVTVAGPDARIDPARLAAAARAKRGDVHTTQPSAVSITQATEV
GSVYTLDEIGAIGEICRAESLSLHMDGARFANALAALGCTPAEMTWRAGVDALSFGATKNGVPGAEAVVLFDTRRAAELA
FRRKRAGHLSSKMRFLSAPLDAYLADALWLRNARHANAMAKRLADGLQALPGVALVGGNAANILFCRLPQALTAGLLAAG
VRFYHDRWAPGVVRFVTSFATTEDEVDRLLALARGLNPADQAPAA

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1787095, Length=198, Percent_Identity=31.3131313131313, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193206520, Length=203, Percent_Identity=27.5862068965517, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193206522, Length=201, Percent_Identity=26.3681592039801, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193206524, Length=201, Percent_Identity=26.3681592039801, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320789, Length=362, Percent_Identity=24.3093922651934, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 37784; Mature: 37784

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHAASPAAPNRADAPLDFSSDNAAGASPAVLDALVACASGRAPAYGADPWTASVERRLA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
ELFEHEVAVSIVPTGTAANSLALAALTPPWGSVLCHPDSHINNDECGAPAFFAGGAKLVT
HHHHCCEEEEEEECCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCCCCEEECCCEEEEE
VAGPDARIDPARLAAAARAKRGDVHTTQPSAVSITQATEVGSVYTLDEIGAIGEICRAES
EECCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEHHHCCCCEEEHHHHHHHHHHHHHCC
LSLHMDGARFANALAALGCTPAEMTWRAGVDALSFGATKNGVPGAEAVVLFDTRRAAELA
CEEEECHHHHHHHHHHHCCCCHHHHHHHCCCHHHCCCCCCCCCCCCEEEEEECHHHHHHH
FRRKRAGHLSSKMRFLSAPLDAYLADALWLRNARHANAMAKRLADGLQALPGVALVGGNA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCCC
ANILFCRLPQALTAGLLAAGVRFYHDRWAPGVVRFVTSFATTEDEVDRLLALARGLNPAD
CEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCC
QAPAA
CCCCC
>Mature Secondary Structure
MEHAASPAAPNRADAPLDFSSDNAAGASPAVLDALVACASGRAPAYGADPWTASVERRLA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
ELFEHEVAVSIVPTGTAANSLALAALTPPWGSVLCHPDSHINNDECGAPAFFAGGAKLVT
HHHHCCEEEEEEECCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCCCCEEECCCEEEEE
VAGPDARIDPARLAAAARAKRGDVHTTQPSAVSITQATEVGSVYTLDEIGAIGEICRAES
EECCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEHHHCCCCEEEHHHHHHHHHHHHHCC
LSLHMDGARFANALAALGCTPAEMTWRAGVDALSFGATKNGVPGAEAVVLFDTRRAAELA
CEEEECHHHHHHHHHHHCCCCHHHHHHHCCCHHHCCCCCCCCCCCCEEEEEECHHHHHHH
FRRKRAGHLSSKMRFLSAPLDAYLADALWLRNARHANAMAKRLADGLQALPGVALVGGNA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCCC
ANILFCRLPQALTAGLLAAGVRFYHDRWAPGVVRFVTSFATTEDEVDRLLALARGLNPAD
CEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCC
QAPAA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]