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The map label for this gene is sdhB [H]

Identifier: 238024244

GI number: 238024244

Start: 1005001

End: 1005702

Strand: Direct

Name: sdhB [H]

Synonym: bglu_2g08260

Alternate gene names: 238024244

Gene position: 1005001-1005702 (Clockwise)

Preceding gene: 238024243

Following gene: 238024245

Centisome position: 35.55

GC content: 63.25

Gene sequence:

>702_bases
ATGGCAAAACGCATTTTCGAACTCTATCGTTACGATCCGGACAAGGACGCGGCGCCGCGCATGCAGACGTACGAAGTCGA
GCTCAAGCATGAACGCATGCTGCTCGACGCGCTGGTCAAGCTGAAGGAAATCGACGAGACGCTGTCGTTCCGTCGCTCGT
GCCGCGAGGGCGTGTGCGGCTCGGACGCGATGAACATCAACGGCAAGAACGGTCTGGCGTGCCTCACGAACCTGAACGAC
CTGCCCGAGAGGATCGTGCTGCGTCCGCTGCCGGGCCTGCCGGTGGTGCGCGACCTGATCGTCGACATGACGCAGTTCTT
CAACCAGTACCACTCGATCAAGCCGTTCCTGATCAACGGCACGCCGCCGCCCGAGAAGGAGCGCCTGCAGTCGCCGGAAG
AGCGCGAGGAGCTGGACGGCGTGTACGAGTGCATCCTGTGCGCGAGCTGCTCGACCTCGTGCCCGAGCTTCTGGTGGAAT
CCGGACAAGTTCGTCGGCCCGGCCGGCCTGCTCCAGGCTTACCGCTTCATCGCCGACAGCCGCGACGAGGCCACCGCCGA
ACGCCTCGACAACCTCGAGGACCCGTACCGTCTGTTCCGTTGCCACACGATCATGAACTGCGTCGACGTTTGCCCGAAGG
GGCTGAACCCGACCAAGGCGATCGGCAAGATCAAGGAATTGATGGTTCGCCGCGCGGTCTGA

Upstream 100 bases:

>100_bases
CGATCGTCTCGACTACAAGCCGGTGCACATGCAGCCGCTGACGGTCGAATCCGTGCCGCCCAAGGCGCGTACGTTCTAAG
CCGAATTCGAGGAATCTGAC

Downstream 100 bases:

>100_bases
GCTGATTCGACATGACTGAACAGTCGCACCAGTCCGACCCGCACCGCCGCGCGCGCCTTCGCTGGCGCGCGCGGCGCGGT
CTGCTGGAGAACGACCTGAT

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MAKRIFELYRYDPDKDAAPRMQTYEVELKHERMLLDALVKLKEIDETLSFRRSCREGVCGSDAMNINGKNGLACLTNLND
LPERIVLRPLPGLPVVRDLIVDMTQFFNQYHSIKPFLINGTPPPEKERLQSPEEREELDGVYECILCASCSTSCPSFWWN
PDKFVGPAGLLQAYRFIADSRDEATAERLDNLEDPYRLFRCHTIMNCVDVCPKGLNPTKAIGKIKELMVRRAV

Sequences:

>Translated_233_residues
MAKRIFELYRYDPDKDAAPRMQTYEVELKHERMLLDALVKLKEIDETLSFRRSCREGVCGSDAMNINGKNGLACLTNLND
LPERIVLRPLPGLPVVRDLIVDMTQFFNQYHSIKPFLINGTPPPEKERLQSPEEREELDGVYECILCASCSTSCPSFWWN
PDKFVGPAGLLQAYRFIADSRDEATAERLDNLEDPYRLFRCHTIMNCVDVCPKGLNPTKAIGKIKELMVRRAV
>Mature_232_residues
AKRIFELYRYDPDKDAAPRMQTYEVELKHERMLLDALVKLKEIDETLSFRRSCREGVCGSDAMNINGKNGLACLTNLNDL
PERIVLRPLPGLPVVRDLIVDMTQFFNQYHSIKPFLINGTPPPEKERLQSPEEREELDGVYECILCASCSTSCPSFWWNP
DKFVGPAGLLQAYRFIADSRDEATAERLDNLEDPYRLFRCHTIMNCVDVCPKGLNPTKAIGKIKELMVRRAV

Specific function: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth [H]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=233, Percent_Identity=58.7982832618026, Blast_Score=276, Evalue=2e-74,
Organism=Escherichia coli, GI1786943, Length=232, Percent_Identity=67.2413793103448, Blast_Score=332, Evalue=2e-92,
Organism=Escherichia coli, GI1790596, Length=225, Percent_Identity=36.8888888888889, Blast_Score=152, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17533915, Length=232, Percent_Identity=53.448275862069, Blast_Score=258, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6322987, Length=228, Percent_Identity=52.6315789473684, Blast_Score=249, Evalue=4e-67,
Organism=Drosophila melanogaster, GI17137106, Length=231, Percent_Identity=56.2770562770563, Blast_Score=269, Evalue=9e-73,
Organism=Drosophila melanogaster, GI24643156, Length=232, Percent_Identity=55.1724137931034, Blast_Score=263, Evalue=6e-71,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 26686; Mature: 26555

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKRIFELYRYDPDKDAAPRMQTYEVELKHERMLLDALVKLKEIDETLSFRRSCREGVCG
CHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SDAMNINGKNGLACLTNLNDLPERIVLRPLPGLPVVRDLIVDMTQFFNQYHSIKPFLING
CCCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECC
TPPPEKERLQSPEEREELDGVYECILCASCSTSCPSFWWNPDKFVGPAGLLQAYRFIADS
CCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCHHHHHHHHHHHHCC
RDEATAERLDNLEDPYRLFRCHTIMNCVDVCPKGLNPTKAIGKIKELMVRRAV
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKRIFELYRYDPDKDAAPRMQTYEVELKHERMLLDALVKLKEIDETLSFRRSCREGVCG
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SDAMNINGKNGLACLTNLNDLPERIVLRPLPGLPVVRDLIVDMTQFFNQYHSIKPFLING
CCCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECC
TPPPEKERLQSPEEREELDGVYECILCASCSTSCPSFWWNPDKFVGPAGLLQAYRFIADS
CCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCHHHHHHHHHHHHCC
RDEATAERLDNLEDPYRLFRCHTIMNCVDVCPKGLNPTKAIGKIKELMVRRAV
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6388571; 8905232; 9278503; 6376123; 9298646 [H]