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The map label for this gene is mocR [H]

Identifier: 238023803

GI number: 238023803

Start: 401367

End: 402959

Strand: Direct

Name: mocR [H]

Synonym: bglu_2g03390

Alternate gene names: 238023803

Gene position: 401367-402959 (Clockwise)

Preceding gene: 238023800

Following gene: 238023804

Centisome position: 14.2

GC content: 74.33

Gene sequence:

>1593_bases
TTGCGGGCGAGCATGTTGTCCGACTGGCTCGCGCAGCGCCTCGTGCGGGGCGGCGGCGCGCAGCCGATCTACCGGCAGCT
GCACCGGCTGCTGCAGCAGGCGATCCTGTCGCGCGAGCTGCCGGCCGGCACGCGCGTGCCGTCGTCGCGGCTGCTCGCGG
CCGAACTCGGGATCGCGCGCAACACCGTCACGCAGGTCTACGAGCAACTGGTGCTGGAGGGCTACGTGACGTCGGCCACC
GGGCGCGGCACGTTCGTGGCCGACAGTTCGCCGGACGAGATCGTCGGCGCGGCCGAGCGGGACGAGGCGGGCGGCGGCGC
GAGCGGAAAGGGCGGCCGCGCGCGCCGGCCGGCGGGGGCCGGCACGGCCGATGCCGCGGCGGGCCCGGGCGGCGCCGGCG
GCCCGCCGGCGCACTCGGCGGGCGGCGCGCTGTCCGCGCGTGGCGCGCGGCTGGTGGCCGGCGCCGGCGTATCGAAGCGC
CAGGGCGGCGCGTTCATGCCCGGCGTGCCCGACGTGTCGCGCTTCCCGGCGCGCGTCTGGATGCGCCTGCACAACAAGTA
TTGGCGCCGCCTGCGCCCCGACCTGCTGACCTACGCGCCGGGCGGCGGCCTCGCCTCGCTGCGCGAGGCGCTGGCCGACT
ACCTGCGGACCTCGCGTTCGGTGCGCTGCACGCCCGAGCAGATCGTGATCACCACCGGCATCCACCAGTCGATCGACCTG
GCGGTGCGGCTGCTGACCGACCCCGGCGACGCGATCTGGACCGAGGATCCGTGCTACTGGGGCATGCGCAGCGTGCTGCA
GGTGTCGGGGCTGACCACGCGGCCGATCGCCGTCGACGACGAGGGCATCGCGCCCGACGCCGCCGATCTGGCGGTGCCGC
CGAAGCTGATGCTCGTCACGCCGTCGCATCAGTACCCGCTCGGCATGGTGATGAGCCTCGCGCGGCGGCGCATGCTGCTC
GAATACGCGCGCCAGCACGGCGCCTGGATCATCGAGGACGACTACGACAGCGAGTTCCGCTACGGCAGCCGGCCGCTCGC
GTCGCTGCAGGGGCTCGACACGAGCGGGCAGGTGATCTACGTGGGCAGCTTCGGCAAGACGCTGTTCCCGGGATTGCGGG
TCGGCTATCTGGTCGCGCCGGAGCCGCTCGCCGGCAGCTTCGCCACCGCGAGCGCCGAGCTGTATCGCGAAGGGCAGCTG
CTGCAGCAGGCGGTGCTGGCCGAGTTCATCGCCGAGGGCCATTTCGTCTCGCATATCCGCAAGATGCGCGCGCTCTACGG
GCTGCGCCGCCAGACGCTGCTCGACGTGCTGGCGCGCCGCTACGGCGATGCGCTGCCGGCCGTGGGCGGGGACGCCGGGC
TGCACCTCGTGATGCGCCTGCCCGACGGCGCCGACGATCAGGCGCTCGCGCGCGCGGCGCTCGAGCGCAACATCGTGGTG
CGCGCGCTGTCCGGCTACTACGCCGACGCGTCGCGCGCGGCGCCGGGGCTGCTGCTCGGCTACGCCTGCGTTCACGAGGA
CGAGATCGGCGCGGCGTTCGACACGCTCGCACAGGCGATCGACGCCGTCGTGTTCGCACGGCGCGCCGGCTGA

Upstream 100 bases:

>100_bases
GTCAATACAGGGGGGCGCGGGGGGCCTCCGACGGAGTTGAATATAATCAAATTTGGCTCTGGAAATCAGAGCCATTTCAG
TAAATCTATAGGAGCCAATT

Downstream 100 bases:

>100_bases
GCGCGCCGCCGCCGGTGGTGCCGGCCGCTTTCAATTCGTCGAGCACGGCGGCCGCGCCCGGTATACCCTTCGAGATGCCG
GCCGGATCCGGGCGGTGGCC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MRASMLSDWLAQRLVRGGGAQPIYRQLHRLLQQAILSRELPAGTRVPSSRLLAAELGIARNTVTQVYEQLVLEGYVTSAT
GRGTFVADSSPDEIVGAAERDEAGGGASGKGGRARRPAGAGTADAAAGPGGAGGPPAHSAGGALSARGARLVAGAGVSKR
QGGAFMPGVPDVSRFPARVWMRLHNKYWRRLRPDLLTYAPGGGLASLREALADYLRTSRSVRCTPEQIVITTGIHQSIDL
AVRLLTDPGDAIWTEDPCYWGMRSVLQVSGLTTRPIAVDDEGIAPDAADLAVPPKLMLVTPSHQYPLGMVMSLARRRMLL
EYARQHGAWIIEDDYDSEFRYGSRPLASLQGLDTSGQVIYVGSFGKTLFPGLRVGYLVAPEPLAGSFATASAELYREGQL
LQQAVLAEFIAEGHFVSHIRKMRALYGLRRQTLLDVLARRYGDALPAVGGDAGLHLVMRLPDGADDQALARAALERNIVV
RALSGYYADASRAAPGLLLGYACVHEDEIGAAFDTLAQAIDAVVFARRAG

Sequences:

>Translated_530_residues
MRASMLSDWLAQRLVRGGGAQPIYRQLHRLLQQAILSRELPAGTRVPSSRLLAAELGIARNTVTQVYEQLVLEGYVTSAT
GRGTFVADSSPDEIVGAAERDEAGGGASGKGGRARRPAGAGTADAAAGPGGAGGPPAHSAGGALSARGARLVAGAGVSKR
QGGAFMPGVPDVSRFPARVWMRLHNKYWRRLRPDLLTYAPGGGLASLREALADYLRTSRSVRCTPEQIVITTGIHQSIDL
AVRLLTDPGDAIWTEDPCYWGMRSVLQVSGLTTRPIAVDDEGIAPDAADLAVPPKLMLVTPSHQYPLGMVMSLARRRMLL
EYARQHGAWIIEDDYDSEFRYGSRPLASLQGLDTSGQVIYVGSFGKTLFPGLRVGYLVAPEPLAGSFATASAELYREGQL
LQQAVLAEFIAEGHFVSHIRKMRALYGLRRQTLLDVLARRYGDALPAVGGDAGLHLVMRLPDGADDQALARAALERNIVV
RALSGYYADASRAAPGLLLGYACVHEDEIGAAFDTLAQAIDAVVFARRAG
>Mature_530_residues
MRASMLSDWLAQRLVRGGGAQPIYRQLHRLLQQAILSRELPAGTRVPSSRLLAAELGIARNTVTQVYEQLVLEGYVTSAT
GRGTFVADSSPDEIVGAAERDEAGGGASGKGGRARRPAGAGTADAAAGPGGAGGPPAHSAGGALSARGARLVAGAGVSKR
QGGAFMPGVPDVSRFPARVWMRLHNKYWRRLRPDLLTYAPGGGLASLREALADYLRTSRSVRCTPEQIVITTGIHQSIDL
AVRLLTDPGDAIWTEDPCYWGMRSVLQVSGLTTRPIAVDDEGIAPDAADLAVPPKLMLVTPSHQYPLGMVMSLARRRMLL
EYARQHGAWIIEDDYDSEFRYGSRPLASLQGLDTSGQVIYVGSFGKTLFPGLRVGYLVAPEPLAGSFATASAELYREGQL
LQQAVLAEFIAEGHFVSHIRKMRALYGLRRQTLLDVLARRYGDALPAVGGDAGLHLVMRLPDGADDQALARAALERNIVV
RALSGYYADASRAAPGLLLGYACVHEDEIGAAFDTLAQAIDAVVFARRAG

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=390, Percent_Identity=23.8461538461538, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI33469970, Length=390, Percent_Identity=23.8461538461538, Blast_Score=111, Evalue=2e-24,
Organism=Escherichia coli, GI1790797, Length=487, Percent_Identity=28.7474332648871, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1787710, Length=291, Percent_Identity=28.1786941580756, Blast_Score=113, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6321236, Length=352, Percent_Identity=22.1590909090909, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21356535, Length=314, Percent_Identity=22.6114649681529, Blast_Score=74, Evalue=4e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 56468; Mature: 56468

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRASMLSDWLAQRLVRGGGAQPIYRQLHRLLQQAILSRELPAGTRVPSSRLLAAELGIAR
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
NTVTQVYEQLVLEGYVTSATGRGTFVADSSPDEIVGAAERDEAGGGASGKGGRARRPAGA
HHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
GTADAAAGPGGAGGPPAHSAGGALSARGARLVAGAGVSKRQGGAFMPGVPDVSRFPARVW
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHH
MRLHNKYWRRLRPDLLTYAPGGGLASLREALADYLRTSRSVRCTPEQIVITTGIHQSIDL
HHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHH
AVRLLTDPGDAIWTEDPCYWGMRSVLQVSGLTTRPIAVDDEGIAPDAADLAVPPKLMLVT
EEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEC
PSHQYPLGMVMSLARRRMLLEYARQHGAWIIEDDYDSEFRYGSRPLASLQGLDTSGQVIY
CCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHCCCCCCCCEEE
VGSFGKTLFPGLRVGYLVAPEPLAGSFATASAELYREGQLLQQAVLAEFIAEGHFVSHIR
EECCCHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
KMRALYGLRRQTLLDVLARRYGDALPAVGGDAGLHLVMRLPDGADDQALARAALERNIVV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
RALSGYYADASRAAPGLLLGYACVHEDEIGAAFDTLAQAIDAVVFARRAG
HHHHCHHCCHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRASMLSDWLAQRLVRGGGAQPIYRQLHRLLQQAILSRELPAGTRVPSSRLLAAELGIAR
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
NTVTQVYEQLVLEGYVTSATGRGTFVADSSPDEIVGAAERDEAGGGASGKGGRARRPAGA
HHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
GTADAAAGPGGAGGPPAHSAGGALSARGARLVAGAGVSKRQGGAFMPGVPDVSRFPARVW
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHH
MRLHNKYWRRLRPDLLTYAPGGGLASLREALADYLRTSRSVRCTPEQIVITTGIHQSIDL
HHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHH
AVRLLTDPGDAIWTEDPCYWGMRSVLQVSGLTTRPIAVDDEGIAPDAADLAVPPKLMLVT
EEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEC
PSHQYPLGMVMSLARRRMLLEYARQHGAWIIEDDYDSEFRYGSRPLASLQGLDTSGQVIY
CCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHCCCCCCCCEEE
VGSFGKTLFPGLRVGYLVAPEPLAGSFATASAELYREGQLLQQAVLAEFIAEGHFVSHIR
EECCCHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
KMRALYGLRRQTLLDVLARRYGDALPAVGGDAGLHLVMRLPDGADDQALARAALERNIVV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
RALSGYYADASRAAPGLLLGYACVHEDEIGAAFDTLAQAIDAVVFARRAG
HHHHCHHCCHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]