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The map label for this gene is aer [H]

Identifier: 238023800

GI number: 238023800

Start: 396692

End: 398236

Strand: Direct

Name: aer [H]

Synonym: bglu_2g03360

Alternate gene names: 238023800

Gene position: 396692-398236 (Clockwise)

Preceding gene: 238023799

Following gene: 238023803

Centisome position: 14.03

GC content: 71.84

Gene sequence:

>1545_bases
ATGCGCAATAACCAGCCCGTCACGCAGCACGAATACGAATTCCCGGAAGACTCGACCCTGATGTCGACGACCACGGCCAA
CGGCACGATCACCTATGCGAACGCGACGTTCGTGCAGGTCAGCGGCTACTCGTCCGAGGAGATCGTCGGCGCGCCGCACA
ACGTCGTCCGCCACCCGGACATGCCGCGCGAGGCGTTCGCGGACATGTGGGCCACCATCCAGGGCGGCGAGCCGTGGATG
GCGCTGGTCAAGAACCGCCGCAAGAACGGCGACCACTATTGGGTGCGCGCGAACGCGGTGCCGCTGATGCGCGGCGGCCG
GCCGGTCGGCTACATGTCGGTGCGCACCCGGCCGGCGCGCGAGGAGATCCAGGCGGCCGAGGCGCTCTACGCCGATTTCC
GCGAGGGCCGCGCGCGCGGCCGGCGCTTCTACAAGGGGCTGGTGGTGCGCGACGGAATCGGGCGCCTGGGCTCGCTGATG
AAGACGATGTCGGTGCGCACGCGGATGGTTGCGCCGCTGGCCGCGCTGGTGCCGGTGGTGGCAGCCGGCGCGTGGGCGTG
CGGCGTGACGGGCGCGGCGCTCGCAGGCGTGGCGGGCACCGCGGCGGTGGCCGCGGGCCTCGTCGCCGCCTGGCTCGACG
TGCAGATCGCGCAGCCGCTGCGCGCGGTGCGGCAGCGCGCGCTGGACGTGGCCACGGGCGAGAATCGCAGCGGCCCGGCC
GTCACGCGCGTCGACGAGATCGGCATGACGCTGCGCACGATCGACCAGCTCGGGCTGATGTTCCGCTGGCTGGTGGACGA
CGTCAGCGAGCAGGTGCTCAACGTGCAGCGCGCGAGCAGCGAGATCGCGCAGGGCAACAACGACCTGAGCGCGCGCACCG
AGCAGGCGGCCACCGCCGTGCAGCAGACCGCCTCGTCGATGGCCCAGATGACGGCCACGGTGTCGAACAACGCGGCCACC
GCCTCGCAGGCGAACCAGCTCGCGGTGTCGGCCAGCGACGCGGCGGCGCGCGGCGGCCATACGGTGGGCGAGATCGTCGG
CACCATGAACGACATCACCGACAGCTCGCGGCGCATCGCCGACATCATCGGCGTGATCGACGGCATCGCGTTCCAGACCA
ACATCCTGGCGCTGAACGCCGCGGTGGAGGCCGCGCGGGCCGGCGAGCAGGGGCGCGGCTTCGCGGTGGTGGCCGGCGAG
GTGCGCGCGCTCGCGCAGCGCAGCGCGAACGCGGCCAAGGAAATCAAGACGCTGATCGAGAACAGCGTCGAGCGCGTGGC
ATCGGGCGCGCGGCGCGTGGACGACGCGGGCCGCGCGATGGACGACCTCGTCGTGCAGGTCAAGCGCGTGGCGGACCTGA
TCGCCGAGATCAGCTCGTCCACCTCCGAGCAGAGCGTGGGCGTGGAGCAGGTCGATCGGGCGGTGGTCGATCTCGACAAC
ATCACGCAGCAGAACGCGGCGCTCGTCGAGCAGAGCGCGGCCGCCTCCGAGAGCCTGCGCCAGCAGGCCACTTCGCTGGT
CGACGCGGTCGGCGTGTTCCGCTGA

Upstream 100 bases:

>100_bases
GCCCGAGGCTGTTGCCGCGCGATGAGGCGCGCGGGCGGCCGATCCAATACCGACCCAAGAGAGCAGACACGGCCGCCCGC
GCCGTGCCCCGGAGCAGCGA

Downstream 100 bases:

>100_bases
ACAACACGGCGTGCGGCTGCGCGTGGCGGCCGCCGAGGCGGCCCATGAGGCGGCCCATGAGGCGGCCCATGAAGCGGGCG
CGGCGCGCGCCATGAAGAAA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MRNNQPVTQHEYEFPEDSTLMSTTTANGTITYANATFVQVSGYSSEEIVGAPHNVVRHPDMPREAFADMWATIQGGEPWM
ALVKNRRKNGDHYWVRANAVPLMRGGRPVGYMSVRTRPAREEIQAAEALYADFREGRARGRRFYKGLVVRDGIGRLGSLM
KTMSVRTRMVAPLAALVPVVAAGAWACGVTGAALAGVAGTAAVAAGLVAAWLDVQIAQPLRAVRQRALDVATGENRSGPA
VTRVDEIGMTLRTIDQLGLMFRWLVDDVSEQVLNVQRASSEIAQGNNDLSARTEQAATAVQQTASSMAQMTATVSNNAAT
ASQANQLAVSASDAAARGGHTVGEIVGTMNDITDSSRRIADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGE
VRALAQRSANAAKEIKTLIENSVERVASGARRVDDAGRAMDDLVVQVKRVADLIAEISSSTSEQSVGVEQVDRAVVDLDN
ITQQNAALVEQSAAASESLRQQATSLVDAVGVFR

Sequences:

>Translated_514_residues
MRNNQPVTQHEYEFPEDSTLMSTTTANGTITYANATFVQVSGYSSEEIVGAPHNVVRHPDMPREAFADMWATIQGGEPWM
ALVKNRRKNGDHYWVRANAVPLMRGGRPVGYMSVRTRPAREEIQAAEALYADFREGRARGRRFYKGLVVRDGIGRLGSLM
KTMSVRTRMVAPLAALVPVVAAGAWACGVTGAALAGVAGTAAVAAGLVAAWLDVQIAQPLRAVRQRALDVATGENRSGPA
VTRVDEIGMTLRTIDQLGLMFRWLVDDVSEQVLNVQRASSEIAQGNNDLSARTEQAATAVQQTASSMAQMTATVSNNAAT
ASQANQLAVSASDAAARGGHTVGEIVGTMNDITDSSRRIADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGE
VRALAQRSANAAKEIKTLIENSVERVASGARRVDDAGRAMDDLVVQVKRVADLIAEISSSTSEQSVGVEQVDRAVVDLDN
ITQQNAALVEQSAAASESLRQQATSLVDAVGVFR
>Mature_514_residues
MRNNQPVTQHEYEFPEDSTLMSTTTANGTITYANATFVQVSGYSSEEIVGAPHNVVRHPDMPREAFADMWATIQGGEPWM
ALVKNRRKNGDHYWVRANAVPLMRGGRPVGYMSVRTRPAREEIQAAEALYADFREGRARGRRFYKGLVVRDGIGRLGSLM
KTMSVRTRMVAPLAALVPVVAAGAWACGVTGAALAGVAGTAAVAAGLVAAWLDVQIAQPLRAVRQRALDVATGENRSGPA
VTRVDEIGMTLRTIDQLGLMFRWLVDDVSEQVLNVQRASSEIAQGNNDLSARTEQAATAVQQTASSMAQMTATVSNNAAT
ASQANQLAVSASDAAARGGHTVGEIVGTMNDITDSSRRIADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGE
VRALAQRSANAAKEIKTLIENSVERVASGARRVDDAGRAMDDLVVQVKRVADLIAEISSSTSEQSVGVEQVDRAVVDLDN
ITQQNAALVEQSAAASESLRQQATSLVDAVGVFR

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=518, Percent_Identity=52.1235521235521, Blast_Score=502, Evalue=1e-143,
Organism=Escherichia coli, GI1788194, Length=303, Percent_Identity=51.1551155115512, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI1788195, Length=234, Percent_Identity=63.2478632478632, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI2367378, Length=314, Percent_Identity=51.9108280254777, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1787690, Length=299, Percent_Identity=48.494983277592, Blast_Score=247, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 54552; Mature: 54552

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNNQPVTQHEYEFPEDSTLMSTTTANGTITYANATFVQVSGYSSEEIVGAPHNVVRHPD
CCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEECEEEEEEECCCCCCCCCCCHHHHCCCC
MPREAFADMWATIQGGEPWMALVKNRRKNGDHYWVRANAVPLMRGGRPVGYMSVRTRPAR
CCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEECCEEECCCCCCCEEEEECCCCHH
EEIQAAEALYADFREGRARGRRFYKGLVVRDGIGRLGSLMKTMSVRTRMVAPLAALVPVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGAWACGVTGAALAGVAGTAAVAAGLVAAWLDVQIAQPLRAVRQRALDVATGENRSGPA
HHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VTRVDEIGMTLRTIDQLGLMFRWLVDDVSEQVLNVQRASSEIAQGNNDLSARTEQAATAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
QQTASSMAQMTATVSNNAATASQANQLAVSASDAAARGGHTVGEIVGTMNDITDSSRRIA
HHHHHHHHHHHHHHCCCCCHHHHHHHEEEECCHHHHCCCCHHHHHHHHHHHHCHHHHHHH
DIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRALAQRSANAAKEIKTLIE
HHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
NSVERVASGARRVDDAGRAMDDLVVQVKRVADLIAEISSSTSEQSVGVEQVDRAVVDLDN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHH
ITQQNAALVEQSAAASESLRQQATSLVDAVGVFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRNNQPVTQHEYEFPEDSTLMSTTTANGTITYANATFVQVSGYSSEEIVGAPHNVVRHPD
CCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEECEEEEEEECCCCCCCCCCCHHHHCCCC
MPREAFADMWATIQGGEPWMALVKNRRKNGDHYWVRANAVPLMRGGRPVGYMSVRTRPAR
CCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEECCEEECCCCCCCEEEEECCCCHH
EEIQAAEALYADFREGRARGRRFYKGLVVRDGIGRLGSLMKTMSVRTRMVAPLAALVPVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGAWACGVTGAALAGVAGTAAVAAGLVAAWLDVQIAQPLRAVRQRALDVATGENRSGPA
HHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VTRVDEIGMTLRTIDQLGLMFRWLVDDVSEQVLNVQRASSEIAQGNNDLSARTEQAATAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
QQTASSMAQMTATVSNNAATASQANQLAVSASDAAARGGHTVGEIVGTMNDITDSSRRIA
HHHHHHHHHHHHHHCCCCCHHHHHHHEEEECCHHHHCCCCHHHHHHHHHHHHCHHHHHHH
DIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRALAQRSANAAKEIKTLIE
HHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
NSVERVASGARRVDDAGRAMDDLVVQVKRVADLIAEISSSTSEQSVGVEQVDRAVVDLDN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHH
ITQQNAALVEQSAAASESLRQQATSLVDAVGVFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]