Click here to switch to the map view.

The map label for this gene is pilQ [H]

Identifier: 237814100

GI number: 237814100

Start: 3737394

End: 3739052

Strand: Reverse

Name: pilQ [H]

Synonym: GBP346_A3886

Alternate gene names: 237814100

Gene position: 3739052-3737394 (Counterclockwise)

Preceding gene: 237814101

Following gene: 237814099

Centisome position: 91.23

GC content: 71.37

Gene sequence:

>1659_bases
TTGCCGCCGCTGCCCGTCGGCGCCCCGTCCGGTTGGTCGGCGTCCGCTTCGGTCGGCGCAGCGGGGCGTGCGCCGTTGCC
GGAGGCGGCCGCGCCGCAATGGCGATTCGATTCGGCGCGCGACCCGGTTGCCGGCGCACCTTCGCCGGATGTGGACGGCG
GGGCGCCAGCGGCTGAATTCGCCGGCGAGGCCACGCCCGAACGCATGCCGGCGGCCCCAACGGCGGAACCGGCCCGCTCG
ACGTCCGCCGACGCCGGAACGTCGAGCGCAGTGGCATCGGCGGGGTTGCAAGCGCAGGAGGCCGCGCTGGAGGGGCCGCC
CGTGCCGCTCGCGCCGGCGCAACGCATGAGCGACGAGAGCGACGAGCATCGTTCGTCGCCGCCGGCCGCCGGCGCCGTAT
CGACCGCGAGCGTCGCCGGCACCGGCACCGAGACGGGCGATCCATCCGGCGACAATCGCCCGATCTCCATCAATCTGCAA
CAGGCGAGCCTCGCCGCGGTCTTCGATGCATTCGCGCGTTTCACGGGCCTCAATATCGTGGTCAGCGAGCGGGTGCGCGG
CACGGTGTCGTTGCGTCTGAACAATGTCCGCTGGCGCAGTGCGTTCGATGCGCTGCTGGACGCCCACGGCCTCGCGATGG
CGCGGCGCGGCAGCGTGATATGGGTGGCGCCCGTCGCGGAACTCGCCGAGCGCGAGCGCCAGCGTTTCGATGCGCATGCG
CGCGCCGCCCAGCTCGAGCCGCTCGCGAGCCGCGGCTTCGTGCTGCGCTACGCGCGCGCGGCCGACGTGCAGCGTCTGCT
CGCAGGCTCGGCCGGCCAGCGCATCCTGTCCAAGCGCGGCTCGGTGTTGGCCGATCCTCGGACGAATCTGCTGTTCGTCA
CCGATCTGTCCGGACGCCTCGCGCAGATCGCCGATCTGATCGGCAAGCTCGATACGCCGTCGCGGCAGGTATTGATCGAA
GCGAGGATCGTCGAGGGGGATCGCGGGTTCTCGCGCAATCTCGGCGCGCGCCTCGCGCTGCGCGCGCCCGATGCGGGCGA
ACGCGCGACGGGCATCGTCGCCGGCCGCAACGGCACGCTGGCGGAGCTCGCCGCCAGGCCGATCAGCGGCTTCGACGCGG
CGACGGCCGGCCTCACGCTGTTCGCCGCGCGCGCGAGCCGCCTGCTCGACGTCGAGTTGAGCGCGCTCGAGGCCGAGGGC
CGGGGCCAGATCGTGTCGAGCCCGCGCGTCGTGACGGCGGACCGGACCAAGGCCGTCGTCGAGCAGGGCGCCGAGCTGCC
GTACCAGGCGAAGGTCGGCAACGGCGTATCCGGCGTCCAGTTCCGGCGCGCGACCTTGAAGCTCGAGGTCGAGCCGCAGA
TCACGCCCGACGGGCGTGTGATTCTCGATCTCGATGTCGCGAAGGATAGCGTCGGCGAGGAAACCGCGTCCGGCCCCGCG
ATTCATACGAAGCATGTGCAGACGCGAGTGGAAGTCGAAAACGGCGGAACGGTGTCGATCGGCGGGATTTTCGAGAGCGA
CGACCGCGACGATGTGACTCGCGTGCCGCTCTTGGGCAAAATACCGGTGTTGGGCGCGCTTTTCAGGCATCGTGCGCAGC
GTGCGCAGCGCAGCGAGCTCGTCGTCTACATCACGCCGACCGTCGTGATCGGGCCCTGA

Upstream 100 bases:

>100_bases
GGCGCGTGATGACCGTCGGGGAAGCGACGGGATGAGGCGCGGGCTCGTTCGATTCTTGCTGGGATGCGCGCTCGGAGCGG
CGGGCGAGGCAGTTGCATCG

Downstream 100 bases:

>100_bases
CGCCCGTGGGAGCCAGGCTCGACAAGGCGGGCGCTTTGCCAGTAAGCTGCGCGACACACTCACTGAAGCAGAGGAAGCCG
TTGCAAGCGCGGGACCCACA

Product: type IV pilus secretin PilQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 552; Mature: 551

Protein sequence:

>552_residues
MPPLPVGAPSGWSASASVGAAGRAPLPEAAAPQWRFDSARDPVAGAPSPDVDGGAPAAEFAGEATPERMPAAPTAEPARS
TSADAGTSSAVASAGLQAQEAALEGPPVPLAPAQRMSDESDEHRSSPPAAGAVSTASVAGTGTETGDPSGDNRPISINLQ
QASLAAVFDAFARFTGLNIVVSERVRGTVSLRLNNVRWRSAFDALLDAHGLAMARRGSVIWVAPVAELAERERQRFDAHA
RAAQLEPLASRGFVLRYARAADVQRLLAGSAGQRILSKRGSVLADPRTNLLFVTDLSGRLAQIADLIGKLDTPSRQVLIE
ARIVEGDRGFSRNLGARLALRAPDAGERATGIVAGRNGTLAELAARPISGFDAATAGLTLFAARASRLLDVELSALEAEG
RGQIVSSPRVVTADRTKAVVEQGAELPYQAKVGNGVSGVQFRRATLKLEVEPQITPDGRVILDLDVAKDSVGEETASGPA
IHTKHVQTRVEVENGGTVSIGGIFESDDRDDVTRVPLLGKIPVLGALFRHRAQRAQRSELVVYITPTVVIGP

Sequences:

>Translated_552_residues
MPPLPVGAPSGWSASASVGAAGRAPLPEAAAPQWRFDSARDPVAGAPSPDVDGGAPAAEFAGEATPERMPAAPTAEPARS
TSADAGTSSAVASAGLQAQEAALEGPPVPLAPAQRMSDESDEHRSSPPAAGAVSTASVAGTGTETGDPSGDNRPISINLQ
QASLAAVFDAFARFTGLNIVVSERVRGTVSLRLNNVRWRSAFDALLDAHGLAMARRGSVIWVAPVAELAERERQRFDAHA
RAAQLEPLASRGFVLRYARAADVQRLLAGSAGQRILSKRGSVLADPRTNLLFVTDLSGRLAQIADLIGKLDTPSRQVLIE
ARIVEGDRGFSRNLGARLALRAPDAGERATGIVAGRNGTLAELAARPISGFDAATAGLTLFAARASRLLDVELSALEAEG
RGQIVSSPRVVTADRTKAVVEQGAELPYQAKVGNGVSGVQFRRATLKLEVEPQITPDGRVILDLDVAKDSVGEETASGPA
IHTKHVQTRVEVENGGTVSIGGIFESDDRDDVTRVPLLGKIPVLGALFRHRAQRAQRSELVVYITPTVVIGP
>Mature_551_residues
PPLPVGAPSGWSASASVGAAGRAPLPEAAAPQWRFDSARDPVAGAPSPDVDGGAPAAEFAGEATPERMPAAPTAEPARST
SADAGTSSAVASAGLQAQEAALEGPPVPLAPAQRMSDESDEHRSSPPAAGAVSTASVAGTGTETGDPSGDNRPISINLQQ
ASLAAVFDAFARFTGLNIVVSERVRGTVSLRLNNVRWRSAFDALLDAHGLAMARRGSVIWVAPVAELAERERQRFDAHAR
AAQLEPLASRGFVLRYARAADVQRLLAGSAGQRILSKRGSVLADPRTNLLFVTDLSGRLAQIADLIGKLDTPSRQVLIEA
RIVEGDRGFSRNLGARLALRAPDAGERATGIVAGRNGTLAELAARPISGFDAATAGLTLFAARASRLLDVELSALEAEGR
GQIVSSPRVVTADRTKAVVEQGAELPYQAKVGNGVSGVQFRRATLKLEVEPQITPDGRVILDLDVAKDSVGEETASGPAI
HTKHVQTRVEVENGGTVSIGGIFESDDRDDVTRVPLLGKIPVLGALFRHRAQRAQRSELVVYITPTVVIGP

Specific function: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=403, Percent_Identity=33.9950372208437, Blast_Score=205, Evalue=6e-54,
Organism=Escherichia coli, GI87082242, Length=382, Percent_Identity=27.4869109947644, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 57481; Mature: 57350

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPLPVGAPSGWSASASVGAAGRAPLPEAAAPQWRFDSARDPVAGAPSPDVDGGAPAAEF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
AGEATPERMPAAPTAEPARSTSADAGTSSAVASAGLQAQEAALEGPPVPLAPAQRMSDES
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHCCCCCCCCCCHHHCCCCC
DEHRSSPPAAGAVSTASVAGTGTETGDPSGDNRPISINLQQASLAAVFDAFARFTGLNIV
HHHCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCEEE
VSERVRGTVSLRLNNVRWRSAFDALLDAHGLAMARRGSVIWVAPVAELAERERQRFDAHA
EECCCCEEEEEEEECEEHHHHHHHHHHHHHHHEECCCCEEEEECHHHHHHHHHHHHHHHH
RAAQLEPLASRGFVLRYARAADVQRLLAGSAGQRILSKRGSVLADPRTNLLFVTDLSGRL
HHHHCCHHHHCCEEEEEHHHHHHHHHHHCCHHHHHHHHCCCEEECCCCCEEEEECCCCHH
AQIADLIGKLDTPSRQVLIEARIVEGDRGFSRNLGARLALRAPDAGERATGIVAGRNGTL
HHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCH
AELAARPISGFDAATAGLTLFAARASRLLDVELSALEAEGRGQIVSSPRVVTADRTKAVV
HHHHCCCCCCCCHHHHHHHHHHHHHHHEEEEEHEEECCCCCCCEECCCEEEECCHHHHHH
EQGAELPYQAKVGNGVSGVQFRRATLKLEVEPQITPDGRVILDLDVAKDSVGEETASGPA
HCCCCCCEEEECCCCCCCCEEEEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCC
IHTKHVQTRVEVENGGTVSIGGIFESDDRDDVTRVPLLGKIPVLGALFRHRAQRAQRSEL
EEEEEEEEEEEECCCCEEEECCEECCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCE
VVYITPTVVIGP
EEEEECEEEECC
>Mature Secondary Structure 
PPLPVGAPSGWSASASVGAAGRAPLPEAAAPQWRFDSARDPVAGAPSPDVDGGAPAAEF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
AGEATPERMPAAPTAEPARSTSADAGTSSAVASAGLQAQEAALEGPPVPLAPAQRMSDES
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHCCCCCCCCCCHHHCCCCC
DEHRSSPPAAGAVSTASVAGTGTETGDPSGDNRPISINLQQASLAAVFDAFARFTGLNIV
HHHCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCEEE
VSERVRGTVSLRLNNVRWRSAFDALLDAHGLAMARRGSVIWVAPVAELAERERQRFDAHA
EECCCCEEEEEEEECEEHHHHHHHHHHHHHHHEECCCCEEEEECHHHHHHHHHHHHHHHH
RAAQLEPLASRGFVLRYARAADVQRLLAGSAGQRILSKRGSVLADPRTNLLFVTDLSGRL
HHHHCCHHHHCCEEEEEHHHHHHHHHHHCCHHHHHHHHCCCEEECCCCCEEEEECCCCHH
AQIADLIGKLDTPSRQVLIEARIVEGDRGFSRNLGARLALRAPDAGERATGIVAGRNGTL
HHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCH
AELAARPISGFDAATAGLTLFAARASRLLDVELSALEAEGRGQIVSSPRVVTADRTKAVV
HHHHCCCCCCCCHHHHHHHHHHHHHHHEEEEEHEEECCCCCCCEECCCEEEECCHHHHHH
EQGAELPYQAKVGNGVSGVQFRRATLKLEVEPQITPDGRVILDLDVAKDSVGEETASGPA
HCCCCCCEEEECCCCCCCCEEEEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCC
IHTKHVQTRVEVENGGTVSIGGIFESDDRDDVTRVPLLGKIPVLGALFRHRAQRAQRSEL
EEEEEEEEEEEECCCCEEEECCEECCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCE
VVYITPTVVIGP
EEEEECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]