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The map label for this gene is aroK [H]

Identifier: 237814099

GI number: 237814099

Start: 3736759

End: 3737388

Strand: Reverse

Name: aroK [H]

Synonym: GBP346_A3885

Alternate gene names: 237814099

Gene position: 3737388-3736759 (Counterclockwise)

Preceding gene: 237814100

Following gene: 237814098

Centisome position: 91.19

GC content: 65.08

Gene sequence:

>630_bases
GTGGGAGCCAGGCTCGACAAGGCGGGCGCTTTGCCAGTAAGCTGCGCGACACACTCACTGAAGCAGAGGAAGCCGTTGCA
AGCGCGGGACCCACACGTGAACGTAATTTTCGTCGGGCTCATGGGGGCGGGTAAGACCACCGTGGGCCGGGCGGTCGCGC
GCCGGCTCGACAGACCCTTCTTCGATTCGGATCATGAGATCGAGGCGCGCACCGGCGCGCGCATTCCGGTCATCTTCGAA
CTCGAGGGCGAAGCGGGCTTCCGTGACCGCGAGGCGCAGATGATCGCCGAGCTCACGCAGCGCGAGAACATCGTGCTGGC
GACGGGCGGCGGCGCGATCCTGCGCCCCGAGAACCGCAAGCTGCTTCACGAACGGGGCCTCGTCGTCTATCTGCGCGCGA
ATCCGCACGATCTCTGGCTGCGCACCCGCAAGGACAAGAATCGCCCGCTGTTGCAGACCGACGATCCGAAAGCCAAGCTC
GAAGCGCTGTACGAAGCGCGCGATCCGCTCTACCGCGAATGCGCGCACTTCGTCATCGAAACCGGGCGGCCGTCCGTCAA
CGGGCTCGTCAACATGGTGCTGATGCAGCTCGAAATGGCGGGCATCGTCGCCAAGCCACTCCAAGCATGA

Upstream 100 bases:

>100_bases
CGGTGTTGGGCGCGCTTTTCAGGCATCGTGCGCAGCGTGCGCAGCGCAGCGAGCTCGTCGTCTACATCACGCCGACCGTC
GTGATCGGGCCCTGACGCCC

Downstream 100 bases:

>100_bases
TTACCGTCAACGTCGACCTGGGCGAGCGCGCCTATCCGATCCACATCGGCGCCGATCTGATCGGCCGCACCGAGCTTTTC
GCGCCGCACATCGCGGGCGC

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MGARLDKAGALPVSCATHSLKQRKPLQARDPHVNVIFVGLMGAGKTTVGRAVARRLDRPFFDSDHEIEARTGARIPVIFE
LEGEAGFRDREAQMIAELTQRENIVLATGGGAILRPENRKLLHERGLVVYLRANPHDLWLRTRKDKNRPLLQTDDPKAKL
EALYEARDPLYRECAHFVIETGRPSVNGLVNMVLMQLEMAGIVAKPLQA

Sequences:

>Translated_209_residues
MGARLDKAGALPVSCATHSLKQRKPLQARDPHVNVIFVGLMGAGKTTVGRAVARRLDRPFFDSDHEIEARTGARIPVIFE
LEGEAGFRDREAQMIAELTQRENIVLATGGGAILRPENRKLLHERGLVVYLRANPHDLWLRTRKDKNRPLLQTDDPKAKL
EALYEARDPLYRECAHFVIETGRPSVNGLVNMVLMQLEMAGIVAKPLQA
>Mature_208_residues
GARLDKAGALPVSCATHSLKQRKPLQARDPHVNVIFVGLMGAGKTTVGRAVARRLDRPFFDSDHEIEARTGARIPVIFEL
EGEAGFRDREAQMIAELTQRENIVLATGGGAILRPENRKLLHERGLVVYLRANPHDLWLRTRKDKNRPLLQTDDPKAKLE
ALYEARDPLYRECAHFVIETGRPSVNGLVNMVLMQLEMAGIVAKPLQA

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=166, Percent_Identity=48.7951807228916, Blast_Score=158, Evalue=2e-40,
Organism=Escherichia coli, GI1786587, Length=155, Percent_Identity=38.0645161290323, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 23315; Mature: 23184

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS01128 SHIKIMATE_KINASE ; PS00267 TACHYKININ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGARLDKAGALPVSCATHSLKQRKPLQARDPHVNVIFVGLMGAGKTTVGRAVARRLDRPF
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCC
FDSDHEIEARTGARIPVIFELEGEAGFRDREAQMIAELTQRENIVLATGGGAILRPENRK
CCCCCCEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCEEECCCCHH
LLHERGLVVYLRANPHDLWLRTRKDKNRPLLQTDDPKAKLEALYEARDPLYRECAHFVIE
HHHHCCEEEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
TGRPSVNGLVNMVLMQLEMAGIVAKPLQA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GARLDKAGALPVSCATHSLKQRKPLQARDPHVNVIFVGLMGAGKTTVGRAVARRLDRPF
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCC
FDSDHEIEARTGARIPVIFELEGEAGFRDREAQMIAELTQRENIVLATGGGAILRPENRK
CCCCCCEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCEEECCCCHH
LLHERGLVVYLRANPHDLWLRTRKDKNRPLLQTDDPKAKLEALYEARDPLYRECAHFVIE
HHHHCCEEEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
TGRPSVNGLVNMVLMQLEMAGIVAKPLQA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA