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The map label for this gene is dtd [H]

Identifier: 237813769

GI number: 237813769

Start: 3432191

End: 3432724

Strand: Reverse

Name: dtd [H]

Synonym: GBP346_A3546

Alternate gene names: 237813769

Gene position: 3432724-3432191 (Counterclockwise)

Preceding gene: 237813770

Following gene: 237813768

Centisome position: 83.75

GC content: 74.16

Gene sequence:

>534_bases
TTGGCCGGGCATGCCGCGCGCGGTGCGCGGCGCCGCGCGTGGCCGCCGCGCCGCGTGCGTGACGCGGACGCGCGCATGAT
CGCCTTGATCCAGCGCGTGAAGCGCGCCGACGTGCGCGTGGGCGAGCGCGTGACGGGCGAGATCGGCCCCGGCCTGCTCG
CGCTCGTGTGCGCGGAGCGCGGCGACACCGAGGCGGCCGCCGACAAGCTGCTCGCGAAGGTGCTCGGCTACCGCGTGTTC
AGTGACGCGGCGGGCAAGATGAACCTGCCCGTGTCGAACCTCGACGGCGCGGGACGCGCGGGCGGGCTGTTGCTCGTGTC
GCAGTTCACGCTCGCCGCCGACACGAACAGCGGCCTGCGCCCGAGCTTCACGCCCGCCGCGCCACCCGACGAGGGCGAGC
GCCTGTTCGACTACTTCGTGCGTCGGGCCCGCGAGCGCCATCCGATCGTCGCGACGGGAGAGTTCGGCGCCGACATGCAG
GTGTCGCTCGTCAACGACGGCCCCGTGACGTTCTGGCTGCAGACGCGCGCCTGA

Upstream 100 bases:

>100_bases
GACAAGGCGCTGAAAGTCGACGCGGGCGAGTTCGTCGTGCAGGTCGGCAAGCGCCGCTTCGCGCGCGTGACGCTTACCGC
ATGAGCGCGCGCATCGCCGC

Downstream 100 bases:

>100_bases
TGCGCCCTTGACGCTCCGATTCGAGACCGCACCGATGCCCACGACGCAGATTCTCTTCATTCGCCATGGCGAGACGGCCT
GGAACCGCATCAAGCGGATT

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MAGHAARGARRRAWPPRRVRDADARMIALIQRVKRADVRVGERVTGEIGPGLLALVCAERGDTEAAADKLLAKVLGYRVF
SDAAGKMNLPVSNLDGAGRAGGLLLVSQFTLAADTNSGLRPSFTPAAPPDEGERLFDYFVRRARERHPIVATGEFGADMQ
VSLVNDGPVTFWLQTRA

Sequences:

>Translated_177_residues
MAGHAARGARRRAWPPRRVRDADARMIALIQRVKRADVRVGERVTGEIGPGLLALVCAERGDTEAAADKLLAKVLGYRVF
SDAAGKMNLPVSNLDGAGRAGGLLLVSQFTLAADTNSGLRPSFTPAAPPDEGERLFDYFVRRARERHPIVATGEFGADMQ
VSLVNDGPVTFWLQTRA
>Mature_176_residues
AGHAARGARRRAWPPRRVRDADARMIALIQRVKRADVRVGERVTGEIGPGLLALVCAERGDTEAAADKLLAKVLGYRVFS
DAAGKMNLPVSNLDGAGRAGGLLLVSQFTLAADTNSGLRPSFTPAAPPDEGERLFDYFVRRARERHPIVATGEFGADMQV
SLVNDGPVTFWLQTRA

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=154, Percent_Identity=37.012987012987, Blast_Score=91, Evalue=5e-19,
Organism=Escherichia coli, GI1790320, Length=149, Percent_Identity=62.4161073825503, Blast_Score=180, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI115533292, Length=154, Percent_Identity=35.7142857142857, Blast_Score=79, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6319982, Length=152, Percent_Identity=38.1578947368421, Blast_Score=89, Evalue=5e-19,
Organism=Drosophila melanogaster, GI281361569, Length=152, Percent_Identity=36.8421052631579, Blast_Score=87, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 19093; Mature: 18962

Theoretical pI: Translated: 10.78; Mature: 10.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGHAARGARRRAWPPRRVRDADARMIALIQRVKRADVRVGERVTGEIGPGLLALVCAER
CCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHCC
GDTEAAADKLLAKVLGYRVFSDAAGKMNLPVSNLDGAGRAGGLLLVSQFTLAADTNSGLR
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCC
PSFTPAAPPDEGERLFDYFVRRARERHPIVATGEFGADMQVSLVNDGPVTFWLQTRA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEECCCCEEEEEEECC
>Mature Secondary Structure 
AGHAARGARRRAWPPRRVRDADARMIALIQRVKRADVRVGERVTGEIGPGLLALVCAER
CCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHCC
GDTEAAADKLLAKVLGYRVFSDAAGKMNLPVSNLDGAGRAGGLLLVSQFTLAADTNSGLR
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCC
PSFTPAAPPDEGERLFDYFVRRARERHPIVATGEFGADMQVSLVNDGPVTFWLQTRA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA