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The map label for this gene is ruvA [H]

Identifier: 237813764

GI number: 237813764

Start: 3427263

End: 3427844

Strand: Direct

Name: ruvA [H]

Synonym: GBP346_A3541

Alternate gene names: 237813764

Gene position: 3427263-3427844 (Clockwise)

Preceding gene: 237813763

Following gene: 237813765

Centisome position: 83.62

GC content: 67.01

Gene sequence:

>582_bases
ATGATCGGTCGCATCGCCGGCACCCTCCTCGAAAAAAATCCGCCGCACATCCTCGTCGACTGCAACGGCGTCGGCTACGA
AGTCGACGTGCCGATGAGCACGTTCTACAACCTGCCGCACACGGGCGAGAAGGTCGTGCTGCTGACCCAGTTGATCGTCC
GCGAGGACGCGCACCTGCTGTACGGCTTTCTCACGCCGCCGGAGCGCTCGACGTTCCGCGAGTTGCTCAAGATCACGGGC
GTCGGCGCGCGGATGGCGCTTGCCGTGCTGTCCGGCATGAGCGTCGCGGAACTGTCGCAAGCGGTCACGCTGCAGGACGC
CGCGCGCCTCACCCGCGTGCCCGGCATCGGCAAGAAAACGGCCGAGCGCCTGCTCCTCGAGCTGAAAGGCAAGCTCGGCG
CCGATCTCGGCCCGCTCGCCGGCGCGGCATCGCCCTCCGACCATGCGACCGACATCCTCAACGCGCTCGTCGCGCTCGGC
TACTCGGAAAAGGAGGCGCTTGCCGCGATCAAGAACGTGCCGGCCGGCACCGGCGTGTCCGAAGGCATCAAGCTGTCGCT
CAAGGCGCTGTCGAAGGCGTAA

Upstream 100 bases:

>100_bases
GTGCGGCGCGGGCGGCTCGTCGGATAACGCGCGACGCACGCCGACGCGCGCGCACCGCGGTGCGCTACACTCGCGCTTTC
CGTTCCGTCCCGCACTCGCC

Downstream 100 bases:

>100_bases
CGGGCCGTGTGCAACGGGGCTGGTGCGTCACGGGCCGTATAACGGGCACGCGTAGCGGGCACGCGTAACGGCGCGTCGTC
GAAGACAGCTTCGCACGCCG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MIGRIAGTLLEKNPPHILVDCNGVGYEVDVPMSTFYNLPHTGEKVVLLTQLIVREDAHLLYGFLTPPERSTFRELLKITG
VGARMALAVLSGMSVAELSQAVTLQDAARLTRVPGIGKKTAERLLLELKGKLGADLGPLAGAASPSDHATDILNALVALG
YSEKEALAAIKNVPAGTGVSEGIKLSLKALSKA

Sequences:

>Translated_193_residues
MIGRIAGTLLEKNPPHILVDCNGVGYEVDVPMSTFYNLPHTGEKVVLLTQLIVREDAHLLYGFLTPPERSTFRELLKITG
VGARMALAVLSGMSVAELSQAVTLQDAARLTRVPGIGKKTAERLLLELKGKLGADLGPLAGAASPSDHATDILNALVALG
YSEKEALAAIKNVPAGTGVSEGIKLSLKALSKA
>Mature_193_residues
MIGRIAGTLLEKNPPHILVDCNGVGYEVDVPMSTFYNLPHTGEKVVLLTQLIVREDAHLLYGFLTPPERSTFRELLKITG
VGARMALAVLSGMSVAELSQAVTLQDAARLTRVPGIGKKTAERLLLELKGKLGADLGPLAGAASPSDHATDILNALVALG
YSEKEALAAIKNVPAGTGVSEGIKLSLKALSKA

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=201, Percent_Identity=44.2786069651741, Blast_Score=165, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 20261; Mature: 20261

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRIAGTLLEKNPPHILVDCNGVGYEVDVPMSTFYNLPHTGEKVVLLTQLIVREDAHLL
CCCHHHHHHHCCCCCEEEEECCCCCEEEECCHHHHCCCCCCCCHHHHHHHHHHHCCCCEE
YGFLTPPERSTFRELLKITGVGARMALAVLSGMSVAELSQAVTLQDAARLTRVPGIGKKT
EEECCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
AERLLLELKGKLGADLGPLAGAASPSDHATDILNALVALGYSEKEALAAIKNVPAGTGVS
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCC
EGIKLSLKALSKA
CCHHHHHHHHCCC
>Mature Secondary Structure
MIGRIAGTLLEKNPPHILVDCNGVGYEVDVPMSTFYNLPHTGEKVVLLTQLIVREDAHLL
CCCHHHHHHHCCCCCEEEEECCCCCEEEECCHHHHCCCCCCCCHHHHHHHHHHHCCCCEE
YGFLTPPERSTFRELLKITGVGARMALAVLSGMSVAELSQAVTLQDAARLTRVPGIGKKT
EEECCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
AERLLLELKGKLGADLGPLAGAASPSDHATDILNALVALGYSEKEALAAIKNVPAGTGVS
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCC
EGIKLSLKALSKA
CCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA