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The map label for this gene is ruvC

Identifier: 237813763

GI number: 237813763

Start: 3426647

End: 3427189

Strand: Direct

Name: ruvC

Synonym: GBP346_A3540

Alternate gene names: 237813763

Gene position: 3426647-3427189 (Clockwise)

Preceding gene: 237813761

Following gene: 237813764

Centisome position: 83.61

GC content: 70.72

Gene sequence:

>543_bases
ATGCGAATCCTCGGCATCGACCCCGGCTTGCGCGTCACGGGCTTCGGCGTGATCGACGTCAGCGGCCACCAGCTCGCGTA
CGTCGCGAGCGGCGTGATCAAGACGCCCACCGCCGATCTGCCCACGCGGCTCGGCACGATCTACGACGGCGTCTCGACGC
TGATCCGCGAGCATACGCCCGATCAGGCGGCGATCGAGAAAGTGTTCGTCAACGTCAATCCGCAATCGACGCTGCTCCTC
GGCCAGGCGCGCGGCGCCGCGATCTGCGGGCTCGTATCGGGCGGCCTGCCCGTCGCCGAGTACACGGCGCTGCAGCTCAA
GCAGGCGGTGGTCGGCTACGGCCGCGCGACGAAAGAGCAGATGCAGGAGATGGTCGCCCGGCTGCTGAGCCTGTCCGGGC
GGCCCGGCACCGACGCGGCCGACGCGCTCGGCATGGCGATCTGCCACGCGCACGGCGGCAACACGCTGAACACGCTCGGC
GGCATCGCGCCCGCGCTCGCGAAAAAGGGGCTGCGCGTGCGGCGCGGGCGGCTCGTCGGATAA

Upstream 100 bases:

>100_bases
GCCGCCGCGCCCGATGCGCCCGGCCCCGCTCTCGCATTGCCGGAATCCAGCCGCGTTCGCTTCGTGTAGTATCGGTCGCA
ATCAGCTTTTCCGTTTCTCC

Downstream 100 bases:

>100_bases
CGCGCGACGCACGCCGACGCGCGCGCACCGCGGTGCGCTACACTCGCGCTTTCCGTTCCGTCCCGCACTCGCCATGATCG
GTCGCATCGCCGGCACCCTC

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MRILGIDPGLRVTGFGVIDVSGHQLAYVASGVIKTPTADLPTRLGTIYDGVSTLIREHTPDQAAIEKVFVNVNPQSTLLL
GQARGAAICGLVSGGLPVAEYTALQLKQAVVGYGRATKEQMQEMVARLLSLSGRPGTDAADALGMAICHAHGGNTLNTLG
GIAPALAKKGLRVRRGRLVG

Sequences:

>Translated_180_residues
MRILGIDPGLRVTGFGVIDVSGHQLAYVASGVIKTPTADLPTRLGTIYDGVSTLIREHTPDQAAIEKVFVNVNPQSTLLL
GQARGAAICGLVSGGLPVAEYTALQLKQAVVGYGRATKEQMQEMVARLLSLSGRPGTDAADALGMAICHAHGGNTLNTLG
GIAPALAKKGLRVRRGRLVG
>Mature_180_residues
MRILGIDPGLRVTGFGVIDVSGHQLAYVASGVIKTPTADLPTRLGTIYDGVSTLIREHTPDQAAIEKVFVNVNPQSTLLL
GQARGAAICGLVSGGLPVAEYTALQLKQAVVGYGRATKEQMQEMVARLLSLSGRPGTDAADALGMAICHAHGGNTLNTLG
GIAPALAKKGLRVRRGRLVG

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=176, Percent_Identity=51.1363636363636, Blast_Score=142, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_BURM7 (A3MP74)

Other databases:

- EMBL:   CP000548
- RefSeq:   YP_001082060.1
- ProteinModelPortal:   A3MP74
- SMR:   A3MP74
- GeneID:   4894519
- GenomeReviews:   CP000548_GR
- KEGG:   bmn:BMA10247_2534
- TIGR:   BMA10247_2534
- HOGENOM:   HBG437552
- OMA:   DCAAIEK
- ProtClustDB:   PRK00039
- BioCyc:   BMAL320389:BMA10247_2534-MONOMER
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 18648; Mature: 18648

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILGIDPGLRVTGFGVIDVSGHQLAYVASGVIKTPTADLPTRLGTIYDGVSTLIREHTP
CEEECCCCCCEEEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
DQAAIEKVFVNVNPQSTLLLGQARGAAICGLVSGGLPVAEYTALQLKQAVVGYGRATKEQ
CHHHHHHHHEECCCCCEEEEECCCCCEEEEHHCCCCCHHHHHHHHHHHHHHHCCCCCHHH
MQEMVARLLSLSGRPGTDAADALGMAICHAHGGNTLNTLGGIAPALAKKGLRVRRGRLVG
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCC
>Mature Secondary Structure
MRILGIDPGLRVTGFGVIDVSGHQLAYVASGVIKTPTADLPTRLGTIYDGVSTLIREHTP
CEEECCCCCCEEEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
DQAAIEKVFVNVNPQSTLLLGQARGAAICGLVSGGLPVAEYTALQLKQAVVGYGRATKEQ
CHHHHHHHHEECCCCCEEEEECCCCCEEEEHHCCCCCHHHHHHHHHHHHHHHCCCCCHHH
MQEMVARLLSLSGRPGTDAADALGMAICHAHGGNTLNTLGGIAPALAKKGLRVRRGRLVG
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA